Annotation Summary for Cell Line: 8305C  

Cell line primary name: 8305C
Cell line aliases:
Gender: F
Site Primary: thyroid
Histology: carcinoma
Hist Subtype1: anaplastic_carcinoma
Notes:
Source: DSMZ
Expression arrays: SILOS_p_NCLE_RNA9_HG-U133_Plus_2_B12_523504
SNP arrays: VAULT_p_NCLE_DNAAffy14_GenomeWideSNP_6_B05_698562
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in 8305C

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 8305C_THYROID 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ABCC3 17 48745203 48745203 8305C_THYROID 37 Intron Del C - uc002isl.2 ABCC3_uc002isk.... Hybrid_Cap...
ADAM28 8 24211994 24211997 8305C_THYROID 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADCK1 14 78390632 78390637 8305C_THYROID 37 Intron Del AAACT... - rs78274857;rs74969652 uc001xui.2 ADCK1_uc010tvo.... Hybrid_Cap...
ALPK1 4 113347609 113347610 8305C_THYROID 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ASTN1 p.L1183V 1 176838080 176838080 8305C_THYROID 37 Missense_Mutation SNP G C uc001glc.2 ASTN1_uc001glb.... Hybrid_Cap... view
ATM p.Q2800* 11 108214078 108214078 8305C_THYROID 37 Nonsense_Mutation SNP C T uc001pkb.1 ATM_uc009yxr.1_... Hybrid_Cap... view
AURKC 19 57742494 57742507 8305C_THYROID 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BRAF p.V600E 7 140453136 140453136 8305C_THYROID 37 Missense_Mutation SNP A T rs113488022 uc003vwc.3 Hybrid_Cap... view
BUB1 p.N534D 2 111415139 111415139 8305C_THYROID 37 Missense_Mutation SNP T C rs36109304 uc002tgc.2 BUB1_uc010yxh.1... Hybrid_Cap... view
CABC1 1 227174571 227174572 8305C_THYROID 37 3'UTR Ins - T uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CACNA1F p.822_825EEEE>E X 49076195 49076203 8305C_THYROID 37 In_Frame_Del Del TCTTC... - rs72212161 uc004dnb.2 CACNA1F_uc010ni... Hybrid_Cap...
CACNA1F p.R83L X 49088167 49088167 8305C_THYROID 37 Missense_Mutation SNP C A uc004dnb.2 CACNA1F_uc010ni... Hybrid_Cap... view
CAD p.I681T 2 27449403 27449403 8305C_THYROID 37 Missense_Mutation SNP T C uc002rji.2 CAD_uc010eyw.2_... Hybrid_Cap... view
CDKN2A 9 21970953 21970953 8305C_THYROID 37 3'UTR SNP C T uc003zpl.2 MTAP_uc003zpi.1... Hybrid_Cap... view
CHD1 5 98192031 98192031 8305C_THYROID 37 3'UTR SNP T C uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 8305C_THYROID 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHRNA5 15 78885615 78885616 8305C_THYROID 37 3'UTR Ins - TA rs72534078 uc002bdy.2 CHRNA3_uc002bea... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 8305C_THYROID 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 8305C_THYROID 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CTBP2 p.K974fs 10 126678123 126678123 8305C_THYROID 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
CYFIP1 p.R190_splice 15 22933559 22933559 8305C_THYROID 37 Splice_Site_SNP SNP A G uc001yus.2 CYFIP1_uc001yut... Hybrid_Cap... view
DACH1 13 72014625 72014626 8305C_THYROID 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DDR2 1 162750211 162750212 8305C_THYROID 37 3'UTR Del TT - uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap...
DGKB 7 14216330 14216332 8305C_THYROID 37 Intron Del AAC - uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap...
EGF p.R394Q 4 110882137 110882137 8305C_THYROID 37 Missense_Mutation SNP G A uc003hzy.3 EGF_uc011cfu.1_... Hybrid_Cap... view
EHBP1 2 63053505 63053505 8305C_THYROID 37 Intron SNP A G uc002sby.2 EHBP1_uc010fcp.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 8305C_THYROID 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
FBN2 p.D548A 5 127714544 127714544 8305C_THYROID 37 Missense_Mutation SNP T G uc003kuu.2 FBN2_uc003kuv.2... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 8305C_THYROID 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 8305C_THYROID 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLT4 5 180035183 180035185 8305C_THYROID 37 Intron Del AGT - uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap...
FN1 2 216244182 216244185 8305C_THYROID 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GLI2 p.N262K 2 121726432 121726432 8305C_THYROID 37 Missense_Mutation SNP C A uc010flp.2 GLI2_uc002tmq.1... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 8305C_THYROID 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318245 122318245 8305C_THYROID 37 5'UTR SNP G C uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap... view
GRIA3 X 122318386 122318387 8305C_THYROID 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 8305C_THYROID 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 8305C_THYROID 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 8305C_THYROID 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSPB1 7 75933564 75933565 8305C_THYROID 37 3'UTR Ins - A uc003uew.2 HSPB1_uc010ldj.... Hybrid_Cap...
IL1R2 p.G366E 2 102644754 102644754 8305C_THYROID 37 Missense_Mutation SNP G A uc002tbm.2 IL1R2_uc002tbn.... Hybrid_Cap... view
ILK 11 6630029 6630029 8305C_THYROID 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 8305C_THYROID 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KALRN p.A2382V 3 124393413 124393413 8305C_THYROID 37 Missense_Mutation SNP C T uc003ehg.2 KALRN_uc003ehi.... Hybrid_Cap... view
LAMA1 p.Y2753H 18 6950921 6950921 8305C_THYROID 37 Missense_Mutation SNP A G uc002knm.2 LAMA1_uc002knk.... Hybrid_Cap... view
LATS2 13 21620223 21620223 8305C_THYROID 37 5'UTR Del A - rs115723063 uc009zzs.2 LATS2_uc001unr.... Hybrid_Cap...
LMNA 1 156106567 156106567 8305C_THYROID 37 Intron SNP C T uc001fni.2 LMNA_uc001fnf.1... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 8305C_THYROID 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K1 15 66679649 66679650 8305C_THYROID 37 5'UTR Ins - C rs67229745 uc010bhq.2 Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 8305C_THYROID 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 8305C_THYROID 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MECOM 3 169381200 169381201 8305C_THYROID 37 5'UTR Ins - T uc011bpj.1 MECOM_uc011bpk.... Hybrid_Cap...
MLLT3 9 20346377 20346378 8305C_THYROID 37 3'UTR Ins - A rs66943046 uc003zoe.2 MLLT3_uc011lne.... Hybrid_Cap...
MMP20 p.L407F 11 102464198 102464198 8305C_THYROID 37 Missense_Mutation SNP G A uc001phc.2 Hybrid_Cap... view
MYST4 p.EEEE1083del 10 76781852 76781863 8305C_THYROID 37 In_Frame_Del Del GAGGA... - rs11001248 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NCAM1 11 112832307 112832308 8305C_THYROID 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 8305C_THYROID 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 8305C_THYROID 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFATC1 p.S299L 18 77171171 77171171 8305C_THYROID 37 Missense_Mutation SNP C T uc010xfg.1 NFATC1_uc002lnc... Hybrid_Cap... view
NFIA 1 61921185 61921186 8305C_THYROID 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NLRP10 p.S325I 11 7982185 7982185 8305C_THYROID 37 Missense_Mutation SNP C A uc001mfv.1 Hybrid_Cap... view
NPM1 5 170837734 170837734 8305C_THYROID 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 8305C_THYROID 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NPRL2 3 50384978 50384978 8305C_THYROID 37 3'UTR Del C - rs75013672 uc003daj.1 ZMYND10_uc003da... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 8305C_THYROID 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NRBP2 p.D481N 8 144917897 144917897 8305C_THYROID 37 Missense_Mutation SNP C T uc011lkt.1 NRBP2_uc003yzv.... Hybrid_Cap... view
NUP214 9 134067556 134067557 8305C_THYROID 37 Intron Ins - T rs66652901 uc004cag.2 NUP214_uc004cah... Hybrid_Cap...
NUP98 11 3697276 3697276 8305C_THYROID 37 3'UTR SNP G A uc001lyh.2 NUP98_uc001lyi.... Hybrid_Cap... view
OBSCN p.F2783L 1 228469785 228469785 8305C_THYROID 37 Missense_Mutation SNP C A uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
PALB2 p.E837K 16 23640966 23640966 8305C_THYROID 37 Missense_Mutation SNP C T uc002dlx.1 Hybrid_Cap... view
PAX3 2 223066017 223066018 8305C_THYROID 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 8305C_THYROID 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PCM1 8 17885407 17885408 8305C_THYROID 37 3'UTR Ins - T rs117750062 uc003wyi.3 PCM1_uc011kyh.1... Hybrid_Cap...
PDE4DIP p.Q432fs 1 144918891 144918892 8305C_THYROID 37 Frame_Shift_Del Del TG - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDK4 7 95221928 95221928 8305C_THYROID 37 Intron Del A - uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap...
PGR 11 100933598 100933599 8305C_THYROID 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PI4K2A 10 99433538 99433538 8305C_THYROID 37 3'UTR SNP T G rs28364829 uc001kog.1 PI4K2A_uc010qoy... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 8305C_THYROID 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PLCG1 p.P284L 20 39792079 39792079 8305C_THYROID 37 Missense_Mutation SNP C T uc002xjo.1 PLCG1_uc002xjp.... Hybrid_Cap... view
PMS1 2 190670539 190670540 8305C_THYROID 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PRKCA 17 64298959 64298960 8305C_THYROID 37 5'UTR Ins - G rs71160558 uc002jfp.1 PRKCA_uc002jfo.... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 8305C_THYROID 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RASGRF1 15 79277150 79277151 8305C_THYROID 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 8305C_THYROID 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RGL2 6 33259806 33259806 8305C_THYROID 37 3'UTR SNP T G uc003odv.2 WDR46_uc003ods.... Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 8305C_THYROID 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SORL1 p.V1899I 11 121489573 121489573 8305C_THYROID 37 Missense_Mutation SNP G A uc001pxx.2 SORL1_uc010rzp.... Hybrid_Cap... view
SSU72 1 1477324 1477325 8305C_THYROID 37 3'UTR Del CA - rs72502747 uc001agd.2 C1orf70_uc009vk... Hybrid_Cap...
STAT1 2 191840353 191840353 8305C_THYROID 37 Intron Del T - uc002usj.2 STAT1_uc010fse.... Hybrid_Cap...
STRN4 p.T479M 19 47228739 47228739 8305C_THYROID 37 Missense_Mutation SNP G A uc002pfm.2 STRN4_uc002pfl.... Hybrid_Cap... view
TEC 4 48139307 48139310 8305C_THYROID 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TERT 5 1282918 1282918 8305C_THYROID 37 Intron SNP G T uc003jcb.1 TERT_uc003jbz.1... Hybrid_Cap... view
TGS1 p.V114_splice 8 56698796 56698796 8305C_THYROID 37 Splice_Site_SNP SNP G C uc003xsj.3 TGS1_uc010lyh.2... Hybrid_Cap... view
TMEM123 11 102269398 102269398 8305C_THYROID 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNKS2 p.P872L 10 93609272 93609272 8305C_THYROID 37 Missense_Mutation SNP C T uc001khp.2 Hybrid_Cap... view
TP53 p.R273C 17 7577121 7577121 8305C_THYROID 37 Missense_Mutation SNP G A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 8305C_THYROID 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIM33 1 114940212 114940212 8305C_THYROID 37 3'UTR Del T - uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRPS1 8 116635872 116635873 8305C_THYROID 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTBK1 p.E771del 6 43250726 43250728 8305C_THYROID 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
TTN 2 179391639 179391640 8305C_THYROID 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.S33249L 2 179392403 179392403 8305C_THYROID 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 8305C_THYROID 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
ZNF423 p.A1283L 16 49525193 49525194 8305C_THYROID 37 Missense_Mutation DNP GC AA uc002efs.2 ZNF423_uc010vgn... Hybrid_Cap...