Annotation Summary for Cell Line: 8505C  

Cell line primary name: 8505C
Cell line aliases:
Gender: F
Site Primary: thyroid
Histology: carcinoma
Hist Subtype1: anaplastic_carcinoma
Notes:
Source: HSRRB
Expression arrays: WATCH_p_NCLE_RNA8_HG-U133_Plus_2_D05_474716
SNP arrays: BOWER_p_NCLE_DNAAffy8_GenomeWideSNP_6_E06_464702
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in 8505C

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 8505C_THYROID 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM28 8 24211994 24211997 8505C_THYROID 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS20 p.L310* 12 43886995 43886995 8505C_THYROID 37 Nonsense_Mutation SNP A C uc010skx.1 Hybrid_Cap... view
AFF1 p.S805N 4 88036399 88036399 8505C_THYROID 37 Missense_Mutation SNP G A uc011ccz.1 AFF1_uc003hqj.3... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 8505C_THYROID 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ASPH p.A264_splice 8 62550924 62550925 8505C_THYROID 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
AURKC 19 57742494 57742507 8505C_THYROID 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BIK p.G153R 22 43525285 43525285 8505C_THYROID 37 Missense_Mutation SNP G A uc003bdk.2 Hybrid_Cap... view
BRAF p.V600E 7 140453136 140453136 8505C_THYROID 37 Missense_Mutation SNP A T rs113488022 uc003vwc.3 Hybrid_Cap... view
CACNB2 10 18828721 18828722 8505C_THYROID 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CAMK2G p.D479N 10 75576760 75576760 8505C_THYROID 37 Missense_Mutation SNP C T uc001jvv.1 CAMK2G_uc001jvm... Hybrid_Cap... view
CARD10 p.KE272del 22 37906309 37906314 8505C_THYROID 37 In_Frame_Del Del CTCCT... - uc003asx.1 CARD10_uc003ast... Hybrid_Cap...
CHD9 p.R178L 16 53190534 53190534 8505C_THYROID 37 Missense_Mutation SNP G T uc002ehb.2 CHD9_uc002egy.2... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 8505C_THYROID 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
COL3A1 p.P126T 2 189850433 189850433 8505C_THYROID 37 Missense_Mutation SNP C A uc002uqj.1 Hybrid_Cap... view
CTBP2 p.K974fs 10 126678123 126678123 8505C_THYROID 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
DDR1 p.P493P 6 30862414 30862414 8505C_THYROID 37 Silent SNP G A uc003nrv.2 DDR1_uc010jse.2... Hybrid_Cap... view
DST 6 56472343 56472344 8505C_THYROID 37 Intron DNP GT AA uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap...
EPHA6 3 97367230 97367231 8505C_THYROID 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ERBB3 p.T618T 12 56488335 56488335 8505C_THYROID 37 Silent SNP C G uc001sjh.2 ERBB3_uc009zoj.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 8505C_THYROID 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 8505C_THYROID 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FOXP1 3 71008341 71008342 8505C_THYROID 37 3'UTR Ins - T rs11433724;rs114233617 uc003dol.2 FOXP1_uc003dom.... Hybrid_Cap...
GPC3 p.T326I X 132887564 132887564 8505C_THYROID 37 Missense_Mutation SNP G A uc010nrn.1 GPC3_uc004exd.1... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 8505C_THYROID 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HSP90B1 p.E791del 12 104341188 104341190 8505C_THYROID 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 8505C_THYROID 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGB4 p.G507S 17 73729635 73729635 8505C_THYROID 37 Missense_Mutation SNP G A uc002jpg.2 ITGB4_uc002jph.... Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 8505C_THYROID 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
LATS2 13 21620222 21620223 8505C_THYROID 37 5'UTR Ins - A rs61240127;rs115723063 uc009zzs.2 LATS2_uc001unr.... Hybrid_Cap...
LMO1 11 8246115 8246115 8505C_THYROID 37 3'UTR SNP G T uc001mgg.1 LMO1_uc009yfo.1... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 8505C_THYROID 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 8505C_THYROID 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K5 6 136878752 136878752 8505C_THYROID 37 3'UTR Del T - rs79903899 uc003qhc.2 MAP3K5_uc011edj... Hybrid_Cap...
MDM2 12 69233761 69233761 8505C_THYROID 37 3'UTR SNP A G uc001sui.2 MDM2_uc009zri.2... Hybrid_Cap... view
MED13L p.E270K 12 116457595 116457595 8505C_THYROID 37 Missense_Mutation SNP C T uc001tvw.2 Hybrid_Cap... view
MGA p.S1629C 15 42035044 42035044 8505C_THYROID 37 Missense_Mutation SNP C G uc010ucy.1 MGA_uc010ucz.1_... Hybrid_Cap... view
MLF1 p.S292L 3 158322966 158322966 8505C_THYROID 37 Missense_Mutation SNP C T uc003fcc.2 MLF1_uc003fbz.2... Hybrid_Cap... view
MTUS2 p.N990H 13 29933431 29933431 8505C_THYROID 37 Missense_Mutation SNP A C uc001usl.3 Hybrid_Cap... view
NCAM1 11 112832307 112832308 8505C_THYROID 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 8505C_THYROID 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK10 p.H418Y 3 27161296 27161296 8505C_THYROID 37 Missense_Mutation SNP G A uc010hfk.2 NEK10_uc010hfj.... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 8505C_THYROID 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NF2 p.E129* 22 30038212 30038212 8505C_THYROID 37 Nonsense_Mutation SNP G T uc003age.3 NF2_uc003afy.3_... Hybrid_Cap... view
NFATC1 18 77287653 77287654 8505C_THYROID 37 3'UTR Del AA - uc010xfg.1 NFATC1_uc002lnd... Hybrid_Cap...
NPR1 1 153665919 153665920 8505C_THYROID 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 8505C_THYROID 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PAX3 2 223158653 223158653 8505C_THYROID 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP p.L601fs 1 144915624 144915624 8505C_THYROID 37 Frame_Shift_Del Del G - rs1778112 uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.E243fs 1 144923729 144923729 8505C_THYROID 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDGFRB p.V221M 5 149513542 149513542 8505C_THYROID 37 Missense_Mutation SNP C T uc003lro.2 PDGFRB_uc010jhd... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 8505C_THYROID 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3C2G 12 18800990 18800990 8505C_THYROID 37 3'UTR Del A - rs16914368 uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 8505C_THYROID 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTK6 p.D224_splice 20 62164902 62164902 8505C_THYROID 37 Splice_Site_SNP SNP A G uc002yfg.2 PTK6_uc011aay.1... Hybrid_Cap... view
RASGRF1 15 79277150 79277151 8505C_THYROID 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RASGRF2 p.R969_splice 5 80497262 80497262 8505C_THYROID 37 Splice_Site_SNP SNP G A uc003kha.1 RASGRF2_uc011ct... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 8505C_THYROID 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RFC4 p.M167T 3 186510647 186510647 8505C_THYROID 37 Missense_Mutation SNP A G uc003fqz.2 RFC4_uc011bsc.1... Hybrid_Cap... view
SIK1 p.C353R 21 44839801 44839801 8505C_THYROID 37 Missense_Mutation SNP A G uc002zdf.2 Hybrid_Cap... view
SMARCA4 p.D694E 19 11118658 11118658 8505C_THYROID 37 Missense_Mutation SNP C G uc010dxo.2 SMARCA4_uc002mq... Hybrid_Cap... view
STK25 2 242435659 242435662 8505C_THYROID 37 Intron Del AAGG - rs3215138;rs75497042 uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap...
STK31 7 23872024 23872025 8505C_THYROID 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TEC 4 48139307 48139310 8505C_THYROID 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TMEM123 11 102269398 102269398 8505C_THYROID 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.R248G 17 7577539 7577539 8505C_THYROID 37 Missense_Mutation SNP G C uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 8505C_THYROID 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIP13 p.E115Q 5 896864 896864 8505C_THYROID 37 Missense_Mutation SNP G C uc003jbr.2 TRIP13_uc010ite... Hybrid_Cap... view
TTN 2 179391639 179391640 8505C_THYROID 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 8505C_THYROID 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
XPO4 p.L499F 13 21382717 21382717 8505C_THYROID 37 Missense_Mutation SNP T A uc001unq.3 Hybrid_Cap... view