Annotation Summary for Cell Line: A172  

Cell line primary name: A172
Cell line aliases:
Gender: M
Site Primary: central_nervous_system
Histology: glioma
Hist Subtype1: astrocytoma_Grade_IV
Notes:
Source: ATCC
Expression arrays: METIS_p_NCLE_RNA1_Human_U133_Plus_2.0_H02_241020
SNP arrays: LOBBY_p_NCLE_DNAAffy6_GenomeWideSNP_6_A01_437348
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in A172

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ACACA 17 35766564 35766564 A172_CENTRAL_NE... 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM28 8 24211994 24211997 A172_CENTRAL_NE... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 A172_CENTRAL_NE... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 A172_CENTRAL_NE... 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.1388_1389FF>F 18 56203253 56203255 A172_CENTRAL_NE... 37 In_Frame_Del Del AAG - uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ARHGAP26 p.E355* 5 142311646 142311646 A172_CENTRAL_NE... 37 Nonsense_Mutation SNP G T uc011dbj.1 ARHGAP26_uc003l... Hybrid_Cap... view
ASPH p.A264_splice 8 62550924 62550925 A172_CENTRAL_NE... 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
ASTN1 p.E886K 1 176903303 176903303 A172_CENTRAL_NE... 37 Missense_Mutation SNP C T uc001glc.2 ASTN1_uc001glb.... Hybrid_Cap... view
BCR 22 23631813 23631814 A172_CENTRAL_NE... 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BTG1 12 92537706 92537707 A172_CENTRAL_NE... 37 3'UTR Ins - T rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
CABC1 1 227171585 227171585 A172_CENTRAL_NE... 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CDK11B 1 1654066 1654068 A172_CENTRAL_NE... 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CDK14 p.S123_splice 7 90356126 90356127 A172_CENTRAL_NE... 37 Splice_Site_Ins Ins - C rs55722725 uc003uky.2 CDK14_uc003ukt.... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 A172_CENTRAL_NE... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CPAMD8 p.P1547L 19 17013645 17013645 A172_CENTRAL_NE... 37 Missense_Mutation SNP G A uc002nfb.2 CPAMD8_uc002nfd... Hybrid_Cap... view
CTBP2 p.K974fs 10 126678123 126678123 A172_CENTRAL_NE... 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
CUBN 10 16866766 16866766 A172_CENTRAL_NE... 37 3'UTR SNP G A uc001ioo.2 Hybrid_Cap... view
DNAH8 p.A1179G 6 38796063 38796063 A172_CENTRAL_NE... 37 Missense_Mutation SNP C G uc003ooe.1 Hybrid_Cap... view
EPHA6 3 97367230 97367231 A172_CENTRAL_NE... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ETV4 p.S457F 17 41605972 41605972 A172_CENTRAL_NE... 37 Missense_Mutation SNP G A uc002idw.2 ETV4_uc002idv.2... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 A172_CENTRAL_NE... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 A172_CENTRAL_NE... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 A172_CENTRAL_NE... 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 A172_CENTRAL_NE... 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 A172_CENTRAL_NE... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
HIPK2 p.S1002Y 7 139259995 139259995 A172_CENTRAL_NE... 37 Missense_Mutation SNP G T uc003vvf.3 HIPK2_uc003vvd.... Hybrid_Cap... view
HNF1A 12 121434630 121434631 A172_CENTRAL_NE... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSP90B1 p.I673N 12 104337643 104337643 A172_CENTRAL_NE... 37 Missense_Mutation SNP T A uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap... view
ILK 11 6630029 6630029 A172_CENTRAL_NE... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGA10 p.R1076_splice 1 145539797 145539797 A172_CENTRAL_NE... 37 Splice_Site_SNP SNP G T uc001eoa.2 NBPF10_uc001emp... Hybrid_Cap... view
ITPR2 p.S700G 12 26810734 26810734 A172_CENTRAL_NE... 37 Missense_Mutation SNP T C uc001rhg.2 Hybrid_Cap... view
JAK3 p.Q228R 19 17953303 17953303 A172_CENTRAL_NE... 37 Missense_Mutation SNP T C uc002nhn.3 JAK3_uc010ebh.2... Hybrid_Cap... view
KLK7 19 51480672 51480675 A172_CENTRAL_NE... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KTN1 p.L605* 14 56105931 56105931 A172_CENTRAL_NE... 37 Nonsense_Mutation SNP T A uc001xcb.2 KTN1_uc001xce.2... Hybrid_Cap... view
LAMA1 p.F2353I 18 6965425 6965425 A172_CENTRAL_NE... 37 Missense_Mutation SNP A T uc002knm.2 LAMA1_uc002knl.... Hybrid_Cap... view
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 A172_CENTRAL_NE... 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 A172_CENTRAL_NE... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K4 p.A1199del 6 161519351 161519353 A172_CENTRAL_NE... 37 In_Frame_Del Del CTG - uc003qtn.2 MAP3K4_uc010kkc... Hybrid_Cap...
MAPKAPK3 3 50685575 50685575 A172_CENTRAL_NE... 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MBIP 14 36768234 36768234 A172_CENTRAL_NE... 37 3'UTR SNP G T uc001wtm.2 MBIP_uc001wto.2... Hybrid_Cap... view
MCF2 p.A406S X 138698596 138698596 A172_CENTRAL_NE... 37 Missense_Mutation SNP C A uc011mwo.1 MCF2_uc004fau.2... Hybrid_Cap... view
MUSK p.G226R 9 113496578 113496578 A172_CENTRAL_NE... 37 Missense_Mutation SNP G C uc004bey.2 MUSK_uc004bex.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 A172_CENTRAL_NE... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 A172_CENTRAL_NE... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 p.V76V 11 113146055 113146055 A172_CENTRAL_NE... 37 Silent SNP C A uc001pnt.2 NCAM1_uc001pns.... Hybrid_Cap... view
NCOA3 p.QQQ1272del 20 46279815 46279823 A172_CENTRAL_NE... 37 In_Frame_Del Del GCAGC... - uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 A172_CENTRAL_NE... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NPM1 5 170837734 170837734 A172_CENTRAL_NE... 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 A172_CENTRAL_NE... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 A172_CENTRAL_NE... 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUMA1 p.A1841T 11 71717252 71717252 A172_CENTRAL_NE... 37 Missense_Mutation SNP C T uc001orl.1 NUMA1_uc001orj.... Hybrid_Cap... view
PAX3 2 223158653 223158653 A172_CENTRAL_NE... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PGR 11 100933598 100933599 A172_CENTRAL_NE... 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3CB p.R153C 3 138461564 138461564 A172_CENTRAL_NE... 37 Missense_Mutation SNP G A uc011bmq.1 Hybrid_Cap... view
PKN2 p.L384del 1 89250482 89250484 A172_CENTRAL_NE... 37 In_Frame_Del Del TCT - uc001dmn.2 PKN2_uc001dmm.1... Hybrid_Cap...
PLEKHA5 p.R1108T 12 19511361 19511361 A172_CENTRAL_NE... 37 Missense_Mutation SNP G C uc010sie.1 PLEKHA5_uc001re... Hybrid_Cap... view
PPM1E p.43_44insEP 17 56833457 56833458 A172_CENTRAL_NE... 37 In_Frame_Ins Ins - GAACCC rs74256772 uc002iwx.2 PPM1E_uc010ddd.... Hybrid_Cap...
PRKCB p.M137I 16 24046750 24046750 A172_CENTRAL_NE... 37 Missense_Mutation SNP G T uc002dme.2 PRKCB_uc002dmd.... Hybrid_Cap... view
PRKD3 2 37480134 37480134 A172_CENTRAL_NE... 37 3'UTR Del C - uc002rqd.2 Hybrid_Cap...
PRKG2 p.L582* 4 82056340 82056340 A172_CENTRAL_NE... 37 Nonsense_Mutation SNP A T uc003hmh.2 PRKG2_uc011ccf.... Hybrid_Cap... view
PTCH1 p.G492R 9 98239858 98239858 A172_CENTRAL_NE... 37 Missense_Mutation SNP C T uc004avk.3 PTCH1_uc010mro.... Hybrid_Cap... view
RB1 p.V852L 13 49050870 49050870 A172_CENTRAL_NE... 37 Missense_Mutation SNP G C uc001vcb.2 Hybrid_Cap... view
RIOK2 p.L168* 5 96508963 96508963 A172_CENTRAL_NE... 37 Nonsense_Mutation SNP A T uc003kmz.2 RIOK2_uc003kna.... Hybrid_Cap... view
RIPK2 p.I418L 8 90801677 90801677 A172_CENTRAL_NE... 37 Missense_Mutation SNP A T uc003yee.2 RIPK2_uc003yef.... Hybrid_Cap... view
SIX4 p.A638V 14 61180558 61180558 A172_CENTRAL_NE... 37 Missense_Mutation SNP G A uc001xfc.2 Hybrid_Cap... view
SPEG p.S1924Y 2 220347956 220347956 A172_CENTRAL_NE... 37 Missense_Mutation SNP C A uc010fwg.2 Hybrid_Cap... view
STK31 7 23872024 23872025 A172_CENTRAL_NE... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TAF1 p.P215L X 70596911 70596911 A172_CENTRAL_NE... 37 Missense_Mutation SNP C T uc004dzt.3 BCYRN1_uc011mpt... Hybrid_Cap... view
TEC 4 48139307 48139310 A172_CENTRAL_NE... 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TNIK 3 170800194 170800194 A172_CENTRAL_NE... 37 Intron SNP A G uc003fhh.2 TNIK_uc003fhi.2... Hybrid_Cap... view
TNRC6B p.Q1328del 22 40697177 40697179 A172_CENTRAL_NE... 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TRIM36 p.R602C 5 114466317 114466317 A172_CENTRAL_NE... 37 Missense_Mutation SNP G A uc003kqs.2 TRIM36_uc011cwc... Hybrid_Cap... view
TRPS1 8 116635872 116635873 A172_CENTRAL_NE... 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN p.R15050C 2 179472662 179472662 A172_CENTRAL_NE... 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.E10139A 2 179542491 179542491 A172_CENTRAL_NE... 37 Missense_Mutation SNP T G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 A172_CENTRAL_NE... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
VEGFC p.S402I 4 177605135 177605135 A172_CENTRAL_NE... 37 Missense_Mutation SNP C A uc003ius.1 Hybrid_Cap... view
WRN p.D844Y 8 30977840 30977840 A172_CENTRAL_NE... 37 Missense_Mutation SNP G T uc003xio.3 WRN_uc010lvk.2_... Hybrid_Cap... view
XPO5 p.C37S 6 43541334 43541334 A172_CENTRAL_NE... 37 Missense_Mutation SNP C G uc003ovp.2 POLH_uc010jyu.2... Hybrid_Cap... view