Annotation Summary for Cell Line: A549  

Cell line primary name: A549
Cell line aliases:
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: non_small_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: METIS_p_NCLE_RNA1_Human_U133_Plus_2.0_H01_241018
SNP arrays: ARLES_p_NCLE_DNAAffy2_S_GenomeWideSNP_6_B06_256036
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in A549

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ACOXL 2 111851275 111851275 A549_LUNG 37 Intron SNP A G uc010yxk.1 ACOXL_uc010fkc.... Hybrid_Cap... view
ADAM17 2 9630245 9630245 A549_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 A549_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS19 p.E398D 5 128864254 128864254 A549_LUNG 37 Missense_Mutation SNP G T uc003kvb.1 ADAMTS19_uc003k... Hybrid_Cap... view
AIM1 p.K782T 6 106968652 106968652 A549_LUNG 37 Missense_Mutation SNP A C rs61739377 uc003prh.2 Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 A549_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 A549_LUNG 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ATR p.R878_splice 3 142272241 142272241 A549_LUNG 37 Splice_Site_SNP SNP C T uc003eux.3 Hybrid_Cap... view
BCL3 19 45262965 45262968 A549_LUNG 37 3'UTR Del CCCC - uc010xxe.1 Hybrid_Cap...
BCR 22 23631813 23631814 A549_LUNG 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BCR 22 23657903 23657903 A549_LUNG 37 3'UTR SNP G T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap... view
BRD3 p.E509del 9 136905272 136905274 A549_LUNG 37 In_Frame_Del Del CTC - uc004cew.2 BRD3_uc004cex.2... Hybrid_Cap...
BTG1 12 92537706 92537707 A549_LUNG 37 3'UTR Ins - T rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
CARD11 p.M1124I 7 2946365 2946365 A549_LUNG 37 Missense_Mutation SNP C T uc003smv.2 Hybrid_Cap... view
CBL p.R585C 11 119156088 119156088 A549_LUNG 37 Missense_Mutation SNP C T uc001pwe.2 Hybrid_Cap... view
CCNB1 5 68462940 68462940 A549_LUNG 37 5'UTR SNP T A uc003jvm.2 CCNB1_uc011crd.... Hybrid_Cap... view
CCNT1 12 49110521 49110521 A549_LUNG 37 5'UTR SNP G A uc001rse.1 CCNT1_uc009zkz.... Hybrid_Cap... view
CHRNB4 p.H339Q 15 78921630 78921630 A549_LUNG 37 Missense_Mutation SNP G T uc002bed.1 CHRNB4_uc002bee... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 A549_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 A549_LUNG 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSF1R 5 149433400 149433401 A549_LUNG 37 3'UTR Ins - C rs66970099;rs78449650 uc003lrl.2 CSF1R_uc011dcd.... Hybrid_Cap...
CYP27B1 12 58156741 58156741 A549_LUNG 37 3'UTR SNP C T uc001spz.1 CYP27B1_uc001sq... Hybrid_Cap... view
DACH1 13 72014625 72014626 A549_LUNG 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DCLK3 p.L43M 3 36780024 36780024 A549_LUNG 37 Missense_Mutation SNP G T uc003cgi.2 Hybrid_Cap... view
EIF4E 4 99808137 99808141 A549_LUNG 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
EPHA1 p.A674G 7 143092474 143092474 A549_LUNG 37 Missense_Mutation SNP G C uc003wcz.2 Hybrid_Cap... view
EPHA6 3 97367230 97367231 A549_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHB6 7 142568771 142568771 A549_LUNG 37 3'UTR Del C - uc011kst.1 EPHB6_uc011ksu.... Hybrid_Cap...
ERC1 p.T1032T 12 1553799 1553799 A549_LUNG 37 Silent SNP C A uc001qjb.2 ERC1_uc001qiz.2... Hybrid_Cap... view
F12 p.V502L 5 176830282 176830282 A549_LUNG 37 Missense_Mutation SNP C G uc003mgo.3 PFN3_uc003mgl.2... Hybrid_Cap... view
FBN2 5 127595063 127595063 A549_LUNG 37 3'UTR SNP C A uc003kuu.2 Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 A549_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 A549_LUNG 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FH p.G464V 1 241661270 241661270 A549_LUNG 37 Missense_Mutation SNP C A uc001hyx.2 Hybrid_Cap... view
FLI1 11 128638217 128638217 A549_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLT3 p.N323K 13 28623588 28623588 A549_LUNG 37 Missense_Mutation SNP G T uc001urw.2 FLT3_uc010aao.2... Hybrid_Cap... view
FLT4 5 180035183 180035185 A549_LUNG 37 Intron Del AGT - uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap...
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 A549_LUNG 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FUS p.R384H 16 31201442 31201442 A549_LUNG 37 Missense_Mutation SNP G A uc002ebi.2 FUS_uc002ebf.2_... Hybrid_Cap... view
GRIA3 X 122318386 122318387 A549_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 A549_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 A549_LUNG 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HIP1 p.S277N 7 75192541 75192541 A549_LUNG 37 Missense_Mutation SNP C T uc003uds.1 HIP1_uc011kfz.1... Hybrid_Cap... view
HIPK3 p.D713G 11 33369293 33369293 A549_LUNG 37 Missense_Mutation SNP A G uc001mul.1 HIPK3_uc001mum.... Hybrid_Cap... view
HNF1A 12 121434630 121434631 A549_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 A549_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 A549_LUNG 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KIAA1549 p.R1603W 7 138552843 138552843 A549_LUNG 37 Missense_Mutation SNP G A uc011kql.1 KIAA1549_uc011k... Hybrid_Cap... view
KLK7 19 51480672 51480675 A549_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KRAS p.G12S 12 25398285 25398285 A549_LUNG 37 Missense_Mutation SNP C T uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
LRP1 p.R678Q 12 57554729 57554729 A549_LUNG 37 Missense_Mutation SNP G A uc001snd.2 Hybrid_Cap... view
LRP2 p.R437I 2 170136891 170136891 A549_LUNG 37 Missense_Mutation SNP C A uc002ues.2 LRP2_uc010zdf.1... Hybrid_Cap... view
MAF 16 79628537 79628537 A549_LUNG 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAGEB16 p.Q23K X 35820380 35820380 A549_LUNG 37 Missense_Mutation SNP C A uc010ngt.1 Hybrid_Cap... view
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 A549_LUNG 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 A549_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 A549_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPKBP1 15 42111753 42111754 A549_LUNG 37 Intron Ins - C rs3034891 uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap...
MCM3APAS 21 47671275 47671276 A549_LUNG 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MLLT3 9 20346377 20346378 A549_LUNG 37 3'UTR Ins - A rs66943046 uc003zoe.2 MLLT3_uc011lne.... Hybrid_Cap...
MSH3 p.PPA66del 5 79950742 79950750 A549_LUNG 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MYO18B p.R2381H 22 26423082 26423082 A549_LUNG 37 Missense_Mutation SNP G A uc003abz.1 MYO18B_uc003aca... Hybrid_Cap... view
NCAM1 11 112832307 112832308 A549_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 A549_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 A549_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFATC1 18 77287653 77287654 A549_LUNG 37 3'UTR Del AA - uc010xfg.1 NFATC1_uc002lnd... Hybrid_Cap...
NIN 14 51190065 51190065 A549_LUNG 37 3'UTR SNP A T uc001wyi.2 NIN_uc001wyj.2_... Hybrid_Cap... view
NPR1 1 153665919 153665920 A549_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 A549_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PAK7 p.K149N 20 9561335 9561335 A549_LUNG 37 Missense_Mutation SNP C A uc002wnl.2 PAK7_uc002wnk.2... Hybrid_Cap... view
PAX3 2 223158653 223158653 A549_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX5 9 37034094 37034095 A549_LUNG 37 5'UTR Del TC - uc003zzo.1 PAX5_uc011lpw.1... Hybrid_Cap...
PGR 11 100933598 100933599 A549_LUNG 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 A549_LUNG 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIP4K2A 10 22825895 22825897 A549_LUNG 37 3'UTR Del CAA - rs117970263;rs34780922;rs117497219 uc001irl.3 PIP4K2A_uc010qc... Hybrid_Cap...
PLK1 p.S595L 16 23701356 23701356 A549_LUNG 37 Missense_Mutation SNP C T rs34001032 uc002dlz.1 Hybrid_Cap... view
POU5F1B p.K195T 8 128428695 128428695 A549_LUNG 37 Missense_Mutation SNP A C uc003ysf.2 LOC727677_uc003... Hybrid_Cap... view
PRKCH 14 61788636 61788636 A549_LUNG 37 5'UTR SNP A G uc001xfn.2 PRKCH_uc010tsa.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 A549_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RASGRF1 15 79277150 79277151 A549_LUNG 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 A549_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROR1 1 64644707 64644707 A549_LUNG 37 3'UTR Del G - rs67076304 uc001dbj.2 Hybrid_Cap...
RPS6KB1 17 58024224 58024225 A549_LUNG 37 3'UTR Ins - AA rs67846207 uc002ixy.2 RPS6KB1_uc010dd... Hybrid_Cap...
SEPT9 17 75494787 75494788 A549_LUNG 37 3'UTR Ins - C rs5822173 uc002jts.3 SEPT9_uc010wtk.... Hybrid_Cap...
SGK269 p.P867Q 15 77471669 77471669 A549_LUNG 37 Missense_Mutation SNP G T uc002bcm.2 SGK269_uc002bcn... Hybrid_Cap... view
SLC6A8 X 152957656 152957657 A549_LUNG 37 Intron Ins - A uc004fib.3 SLC6A8_uc004fic... Hybrid_Cap...
SMARCA4 p.L728fs 19 11121117 11121139 A549_LUNG 37 Frame_Shift_Del Del GCAGT... - uc010dxo.2 SMARCA4_uc002mq... Hybrid_Cap...
STAT5B 17 40353573 40353573 A549_LUNG 37 3'UTR SNP A C uc002hzh.2 Hybrid_Cap... view
STK31 7 23872024 23872025 A549_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
STK32A p.Q138K 5 146703612 146703612 A549_LUNG 37 Missense_Mutation SNP C A uc011dbw.1 STK32A_uc003lol... Hybrid_Cap... view
SUFU p.T411M 10 104377121 104377121 A549_LUNG 37 Missense_Mutation SNP C T uc001kvy.1 SUFU_uc001kvw.1... Hybrid_Cap... view
TEC 4 48139307 48139310 A549_LUNG 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TGFB2 1 218519928 218519929 A549_LUNG 37 5'UTR Ins - AAAC uc001hln.2 TGFB2_uc001hll.... Hybrid_Cap...
TMEM123 11 102269398 102269398 A549_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNN p.V353M 1 175052894 175052894 A549_LUNG 37 Missense_Mutation SNP G A uc001gkl.1 TNN_uc010pmx.1_... Hybrid_Cap... view
TNRC6B p.Q1328del 22 40697177 40697179 A549_LUNG 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TP63 3 189507518 189507519 A549_LUNG 37 Intron Ins - AG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIM33 1 114940212 114940212 A549_LUNG 37 3'UTR Del T - uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TTBK1 p.E771del 6 43250726 43250728 A549_LUNG 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
TTN 2 179391639 179391640 A549_LUNG 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.P25033T 2 179428058 179428058 A549_LUNG 37 Missense_Mutation SNP G T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
USP6 p.P31T 17 5033915 5033915 A549_LUNG 37 Missense_Mutation SNP C A uc002gau.1 USP6_uc002gav.1... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 A549_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
ZAP70 2 98351655 98351655 A549_LUNG 37 Intron Del G - uc002syd.1 ZAP70_uc010yvf.... Hybrid_Cap...