Annotation Summary for Cell Line: ALL-SIL  

Cell line primary name: ALL-SIL
Cell line aliases:
Gender: M
Site Primary: haematopoietic_and_lymphoid_tissue
Histology: lymphoid_neoplasm
Hist Subtype1: acute_lymphoblastic_T_cell_leukaemia
Notes:
Source: DSMZ
Expression arrays: SILOS_p_NCLE_RNA9_HG-U133_Plus_2_C02_523526
SNP arrays: EPHOR_p_NCLE_Achilles_DNAAffy15_GenomeWideSNP_6_C09_780208
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in ALL-SIL

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AATK p.E143V 17 79101697 79101697 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP T A uc010dia.2 MIR657_hsa-mir-... Hybrid_Cap... view
ADAM17 2 9630245 9630245 ALLSIL_HAEMATOP... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 ALLSIL_HAEMATOP... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAM29 p.Q796P 4 175899063 175899063 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP A C uc003iuc.2 ADAM29_uc003iud... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 ALLSIL_HAEMATOP... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK2 p.1388_1389FF>F 18 56203253 56203255 ALLSIL_HAEMATOP... 37 In_Frame_Del Del AAG - uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ARID1A 1 27107263 27107264 ALLSIL_HAEMATOP... 37 3'UTR Ins - C rs3841356 uc001bmv.1 ARID1A_uc001bmu... Hybrid_Cap...
BCR 22 23631813 23631814 ALLSIL_HAEMATOP... 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BCR 22 23632777 23632778 ALLSIL_HAEMATOP... 37 Intron Ins - T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
CAD p.V1596M 2 27460981 27460981 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP G A uc002rji.2 CAD_uc010eyw.2_... Hybrid_Cap... view
CAMK2A p.V73I 5 149644519 149644519 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP C T uc003lrt.2 CAMK2A_uc003lru... Hybrid_Cap... view
CDC42BPA p.G292R 1 227335080 227335080 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP C T uc001hqr.2 CDC42BPA_uc001h... Hybrid_Cap... view
CHD9 p.2164_2165SS>S 16 53338410 53338412 ALLSIL_HAEMATOP... 37 In_Frame_Del Del TTC - uc002ehb.2 CHD9_uc002egy.2... Hybrid_Cap...
CIT 12 120125896 120125896 ALLSIL_HAEMATOP... 37 3'UTR SNP C T uc001txj.1 CIT_uc001txh.1_... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 ALLSIL_HAEMATOP... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 ALLSIL_HAEMATOP... 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CTDSPL p.L251R 3 38022279 38022279 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP T G uc003chg.2 CTDSPL_uc003chh... Hybrid_Cap... view
DYRK1A 21 38884966 38884967 ALLSIL_HAEMATOP... 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EIF4E 4 99808137 99808141 ALLSIL_HAEMATOP... 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
EPHA6 3 97367230 97367231 ALLSIL_HAEMATOP... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ERBB3 12 56492422 56492423 ALLSIL_HAEMATOP... 37 Intron Ins - C uc001sjh.2 ERBB3_uc009zoj.... Hybrid_Cap...
ERBB4 p.A17V 2 213403205 213403205 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP G A uc002veg.1 ERBB4_uc002veh.... Hybrid_Cap... view
ETV1 7 14028708 14028708 ALLSIL_HAEMATOP... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FAM132A 1 1177919 1177919 ALLSIL_HAEMATOP... 37 3'UTR Del T - uc001adl.1 Hybrid_Cap...
FANCC 9 97863891 97863892 ALLSIL_HAEMATOP... 37 3'UTR Ins - C uc004avh.2 Hybrid_Cap...
FANCD2 p.R1097Q 3 10127561 10127561 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP G A uc003buw.2 FANCD2_uc003bux... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 ALLSIL_HAEMATOP... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 ALLSIL_HAEMATOP... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 ALLSIL_HAEMATOP... 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GRIA3 X 122318386 122318387 ALLSIL_HAEMATOP... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GSK3A 19 42744353 42744353 ALLSIL_HAEMATOP... 37 Intron SNP C T uc002otb.1 GSK3A_uc002ota.... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 ALLSIL_HAEMATOP... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HNF1A 12 121434630 121434631 ALLSIL_HAEMATOP... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
IGF1R 15 99192755 99192762 ALLSIL_HAEMATOP... 37 5'UTR Del TTTTT... - uc002bul.2 IGF1R_uc010urq.... Hybrid_Cap...
ILK 11 6630029 6630029 ALLSIL_HAEMATOP... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 ALLSIL_HAEMATOP... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KALRN p.R907C 3 124149518 124149518 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP C T uc003ehg.2 KALRN_uc010hrv.... Hybrid_Cap... view
KIAA1549 7 138604289 138604289 ALLSIL_HAEMATOP... 37 Intron SNP C T uc011kql.1 KIAA1549_uc003v... Hybrid_Cap... view
KLK7 19 51480672 51480675 ALLSIL_HAEMATOP... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LRRC7 p.R915C 1 70504364 70504364 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP C T uc001dep.2 LRRC7_uc009wbg.... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 ALLSIL_HAEMATOP... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 ALLSIL_HAEMATOP... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K11 p.M289V 11 65375794 65375794 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP T C uc001oew.2 MAP3K11_uc001oe... Hybrid_Cap... view
MAP3K14 p.R218_splice 17 43364293 43364294 ALLSIL_HAEMATOP... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP4K1 19 39078374 39078375 ALLSIL_HAEMATOP... 37 3'UTR Ins - C uc002oix.1 MAP4K1_uc002oiw... Hybrid_Cap...
MAPK14 6 36076345 36076354 ALLSIL_HAEMATOP... 37 3'UTR Del GTGTG... - rs80147786 uc003olp.2 MAPK14_uc003olq... Hybrid_Cap...
MAPKAPK3 3 50685575 50685575 ALLSIL_HAEMATOP... 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MAPKBP1 15 42111727 42111727 ALLSIL_HAEMATOP... 37 Intron SNP G A uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap... view
MAPKBP1 15 42111753 42111754 ALLSIL_HAEMATOP... 37 Intron Ins - C rs3034891 uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap...
MGA p.K1978R 15 42041738 42041738 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP A G uc010ucy.1 MGA_uc010ucz.1_... Hybrid_Cap... view
MLLT3 9 20346378 20346378 ALLSIL_HAEMATOP... 37 3'UTR Del A - uc003zoe.2 MLLT3_uc011lne.... Hybrid_Cap...
NCAM1 11 112832307 112832308 ALLSIL_HAEMATOP... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 ALLSIL_HAEMATOP... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 ALLSIL_HAEMATOP... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NOTCH1 p.V2473fs 9 139390772 139390773 ALLSIL_HAEMATOP... 37 Frame_Shift_Ins Ins - CC uc004chz.2 Hybrid_Cap...
NOTCH1 p.L2457V 9 139390822 139390822 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP G C rs61755043 uc004chz.2 Hybrid_Cap... view
NOTCH1 p.L1593P 9 139399365 139399365 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP A G uc004chz.2 NOTCH1_uc004cia... Hybrid_Cap... view
NPR1 1 153665919 153665920 ALLSIL_HAEMATOP... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 ALLSIL_HAEMATOP... 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PAX5 9 37034095 37034095 ALLSIL_HAEMATOP... 37 5'UTR Del C - uc003zzo.1 PAX5_uc011lpw.1... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 ALLSIL_HAEMATOP... 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PLD1 p.I668F 3 171394618 171394618 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP T A uc003fhs.2 PLD1_uc003fht.2... Hybrid_Cap... view
PPP3R1 p.F15_splice 2 68415824 68415824 ALLSIL_HAEMATOP... 37 Splice_Site_SNP SNP T A uc002sei.1 Hybrid_Cap... view
PRKAA2 p.I32_splice 1 57140052 57140052 ALLSIL_HAEMATOP... 37 Splice_Site_SNP SNP A T uc001cyk.3 Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 ALLSIL_HAEMATOP... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PSKH1 p.P229L 16 67943338 67943338 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP C T uc002euv.2 PSKH1_uc010cet.... Hybrid_Cap... view
ROBO2 p.V649L 3 77617547 77617547 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP G C uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap... view
SMURF2 p.Q63Q 17 62594511 62594511 ALLSIL_HAEMATOP... 37 Silent SNP C T uc002jep.1 SMURF2_uc002jeq... Hybrid_Cap... view
SPEN p.T1258S 1 16256507 16256507 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP A T uc001axk.1 SPEN_uc010obp.1... Hybrid_Cap... view
TAF1L p.P516H 9 32634031 32634031 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP G T uc003zrg.1 Hybrid_Cap... view
TCF21 6 134210497 134210498 ALLSIL_HAEMATOP... 37 5'UTR Ins - TCTC rs35199378 uc003qei.3 TCF21_uc003qej.... Hybrid_Cap...
TP63 3 189507518 189507519 ALLSIL_HAEMATOP... 37 Intron Ins - AG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TPM3 1 154164530 154164530 ALLSIL_HAEMATOP... 37 5'UTR SNP T C uc001fec.1 Hybrid_Cap... view
TSC2 16 2138671 2138672 ALLSIL_HAEMATOP... 37 3'UTR Del AA - uc002con.2 TSC2_uc010bsd.2... Hybrid_Cap...
TTN 2 179391639 179391640 ALLSIL_HAEMATOP... 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.F32806Y 2 179395221 179395221 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP A T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.P19277L 2 179448375 179448375 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.P17706L 2 179455631 179455631 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP G A rs72646845 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 ALLSIL_HAEMATOP... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WNK1 p.Q201E 12 863332 863332 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP C G uc001qio.3 WNK1_uc001qin.2... Hybrid_Cap... view
YES1 p.Y32C 18 756733 756733 ALLSIL_HAEMATOP... 37 Missense_Mutation SNP T C uc002kky.2 YES1_uc002kkz.2... Hybrid_Cap... view