Annotation Summary for Cell Line: BxPC-3  

Cell line primary name: BxPC-3
Cell line aliases:
Gender: F
Site Primary: pancreas
Histology: carcinoma
Hist Subtype1: ductal_carcinoma
Notes:
Source: ATCC
Expression arrays: CASED_p_NCLE_RNA4_HG-U133_Plus_2_H08_383778
SNP arrays: LIMPS_p_NCLE_DNA2N_GenomeWideSNP_6_G02_246756
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in BxPC-3

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 BXPC3_PANCREAS 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM17 2 9630245 9630245 BXPC3_PANCREAS 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 BXPC3_PANCREAS 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 BXPC3_PANCREAS 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP6 p.T80S 14 32902937 32902937 BXPC3_PANCREAS 37 Missense_Mutation SNP A T uc001wrq.2 AKAP6_uc010aml.... Hybrid_Cap... view
ALPK2 p.EDTST1006del 18 56204388 56204402 BXPC3_PANCREAS 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
BCL11B 14 99640466 99640466 BXPC3_PANCREAS 37 3'UTR SNP C G uc001yga.2 BCL11B_uc001ygb... Hybrid_Cap... view
BMP4 14 54416601 54416602 BXPC3_PANCREAS 37 3'UTR Ins - AT rs74495140;rs76335800 uc001xal.3 BMP4_uc010aoh.2... Hybrid_Cap...
CACNB2 p.S293L 16 89761424 89761424 BXPC3_PANCREAS 37 Missense_Mutation SNP C T uc010cio.2 CDK10_uc002fod.... Hybrid_Cap... view
CACNB2 10 18828669 18828670 BXPC3_PANCREAS 37 3'UTR Ins - C rs34022725;rs58830289 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDC73 p.V1201_splice 22 19189003 19189004 BXPC3_PANCREAS 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CDK11B 3 1339681 1339686 BXPC3_PANCREAS 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CDK18 1 205495890 205495891 BXPC3_PANCREAS 37 Intron Del CT - uc001hcr.2 CDK18_uc010pri.... Hybrid_Cap...
CHD1 p.P1684del 5 98192165 98192167 BXPC3_PANCREAS 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 BXPC3_PANCREAS 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CTBP2 p.R397* 22 41525914 41525914 BXPC3_PANCREAS 37 Nonsense_Mutation SNP C T uc003azl.3 Hybrid_Cap... view
DBF4 p.D82G 7 87514319 87514319 BXPC3_PANCREAS 37 Missense_Mutation SNP A G uc003ujf.1 DBF4_uc003ujh.1... Hybrid_Cap... view
DMPK p.V173I 19 46281893 46281893 BXPC3_PANCREAS 37 Missense_Mutation SNP C T uc002pdi.1 DMPK_uc010xxs.1... Hybrid_Cap... view
DYRK1A 21 38884966 38884967 BXPC3_PANCREAS 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EDN1 6 12290729 12290729 BXPC3_PANCREAS 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EIF4B 7 14028708 14028708 BXPC3_PANCREAS 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
EPHA6 3 97367230 97367231 BXPC3_PANCREAS 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ERCC6 p.I422F 10 50732212 50732212 BXPC3_PANCREAS 37 Missense_Mutation SNP T A uc001jhs.3 PGBD3_uc001jht.... Hybrid_Cap... view
EXT1 8 118811807 118811807 BXPC3_PANCREAS 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
FBN1 p.A979T 15 48782195 48782195 BXPC3_PANCREAS 37 Missense_Mutation SNP C T uc001zwx.1 Hybrid_Cap... view
FGFR3 4 1809128 1809129 BXPC3_PANCREAS 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 BXPC3_PANCREAS 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLI1 p.D2657del X 135474445 135474447 BXPC3_PANCREAS 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 BXPC3_PANCREAS 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 BXPC3_PANCREAS 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 12 121434630 121434631 BXPC3_PANCREAS 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HNF1A 5 179050364 179050364 BXPC3_PANCREAS 37 Intron SNP G C uc003mkf.3 HNRNPH1_uc003mk... Hybrid_Cap... view
ILK 11 6630029 6630029 BXPC3_PANCREAS 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ILK p.Y404S 7 41729318 41729318 BXPC3_PANCREAS 37 Missense_Mutation SNP T G rs113772875 uc003thq.2 INHBA_uc003thr.... Hybrid_Cap... view
INSRR p.G331V 1 156821530 156821530 BXPC3_PANCREAS 37 Missense_Mutation SNP C A uc010pht.1 NTRK1_uc001fqf.... Hybrid_Cap... view
IRAK3 p.K240E 6 15487585 15487585 BXPC3_PANCREAS 37 Missense_Mutation SNP A G uc003nbj.2 JARID2_uc011diu... Hybrid_Cap... view
ITPR2 19 51480672 51480675 BXPC3_PANCREAS 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 BXPC3_PANCREAS 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KRAS p.R218_splice 17 43364293 43364294 BXPC3_PANCREAS 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
LRRK2 p.R393L 20 62839727 62839727 BXPC3_PANCREAS 37 Missense_Mutation SNP G T uc002yii.2 MYT1_uc002yih.2... Hybrid_Cap... view
MAF 16 79628325 79628325 BXPC3_PANCREAS 37 3'UTR Del A - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 BXPC3_PANCREAS 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 BXPC3_PANCREAS 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MEN1 9 134067556 134067557 BXPC3_PANCREAS 37 Intron Ins - T rs66652901 uc004cag.2 NUP214_uc004cah... Hybrid_Cap...
NCAM1 11 112832307 112832308 BXPC3_PANCREAS 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 BXPC3_PANCREAS 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 p.K161E 11 113078643 113078643 BXPC3_PANCREAS 37 Missense_Mutation SNP A G uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap... view
NCAM1 p.V486fs 1 144917828 144917828 BXPC3_PANCREAS 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
NCAM1 1 144931366 144931367 BXPC3_PANCREAS 37 Intron DNP CC TA uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
NCOA3 p.QQQ1272del 20 46279815 46279823 BXPC3_PANCREAS 37 In_Frame_Del Del GCAGC... - uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK3 p.P129del 12 18435399 18435401 BXPC3_PANCREAS 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
NEK9 12 18800990 18800990 BXPC3_PANCREAS 37 3'UTR Del A - rs16914368 uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
NFIA 5 57754052 57754052 BXPC3_PANCREAS 37 Intron SNP A G uc003jrn.2 PLK2_uc011cql.1... Hybrid_Cap... view
NPR1 1 153665919 153665920 BXPC3_PANCREAS 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NPR1 p.L1244fs 8 48805816 48805817 BXPC3_PANCREAS 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 BXPC3_PANCREAS 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR3C1 5 142780419 142780419 BXPC3_PANCREAS 37 Splice_Site_SNP SNP T A uc003lmy.2 NR3C1_uc003lmz.... Hybrid_Cap... view
PAX3 2 223158653 223158653 BXPC3_PANCREAS 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP p.Y220C 17 7578190 7578190 BXPC3_PANCREAS 37 Missense_Mutation SNP T C uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
PDE4DIP p.Q1665fs 1 144873963 144873963 BXPC3_PANCREAS 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PGR p.R14123T 2 179477180 179477180 BXPC3_PANCREAS 37 Missense_Mutation SNP C G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
PMS1 2 190670539 190670540 BXPC3_PANCREAS 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PPP3R1 p.F15_splice 2 68415824 68415824 BXPC3_PANCREAS 37 Splice_Site_SNP SNP T A uc002sei.1 Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 BXPC3_PANCREAS 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
REM1 20 30064232 30064233 BXPC3_PANCREAS 37 5'UTR Ins - C uc002wwa.2 Hybrid_Cap...
RGL1 p.L212L 2 135745806 135745806 BXPC3_PANCREAS 37 Silent SNP C T uc002tue.1 YSK4_uc002tuf.1... Hybrid_Cap... view
RNASEL p.M641T 1 182545508 182545508 BXPC3_PANCREAS 37 Missense_Mutation SNP A G uc001gpj.1 RNASEL_uc009wxz... Hybrid_Cap... view
SLC45A3 p.D547N 1 205628385 205628385 BXPC3_PANCREAS 37 Missense_Mutation SNP C T uc001hda.1 SLC45A3_uc010pr... Hybrid_Cap... view
TEC 4 48139307 48139310 BXPC3_PANCREAS 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TRPS1 8 116635872 116635873 BXPC3_PANCREAS 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN 2 179391639 179391640 BXPC3_PANCREAS 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.T799M 2 179650444 179650444 BXPC3_PANCREAS 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 BXPC3_PANCREAS 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
VPS13B 8 100887922 100887923 BXPC3_PANCREAS 37 3'UTR Del TG - uc003yiv.2 VPS13B_uc003yiw... Hybrid_Cap...