Annotation Summary for Cell Line: C3A  

Cell line primary name: C3A
Cell line aliases:
Gender: M
Site Primary: liver
Histology: carcinoma
Hist Subtype1: hepatocellular_carcinoma
Notes: Identical lines: Hep G2 and C3A share high SNP identity
Source: ATCC
Expression arrays: AGENT_p_NCLE_RNA6_HG-U133_Plus_2_E07_436554
SNP arrays: FASTS_p_NCLE_DNAAffy4_S_GenomeWideSNP_6_E10_335302
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in C3A

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABL2 1 179086419 179086420 C3A_LIVER 37 Intron Ins - A rs72207641 uc001gmj.3 ABL2_uc010pnf.1... Hybrid_Cap...
ADAM17 2 9630245 9630245 C3A_LIVER 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24193348 24193348 C3A_LIVER 37 Intron SNP C T uc003xdy.2 ADAM28_uc003xdx... Hybrid_Cap... view
ADAM28 8 24211994 24211997 C3A_LIVER 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTSL3 p.S1189L 15 84651946 84651946 C3A_LIVER 37 Missense_Mutation SNP C T uc002bjz.3 ADAMTSL3_uc010b... Hybrid_Cap... view
ALPK1 p.A484S 4 113352153 113352153 C3A_LIVER 37 Missense_Mutation SNP G T uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap... view
ATM p.V2906I 11 108224537 108224537 C3A_LIVER 37 Missense_Mutation SNP G A uc001pkb.1 ATM_uc009yxr.1_... Hybrid_Cap... view
BCAR1 p.P186T 16 75276583 75276583 C3A_LIVER 37 Missense_Mutation SNP G T uc010vnb.1 BCAR1_uc010cgu.... Hybrid_Cap... view
BMPR1A p.I517V 10 88683426 88683426 C3A_LIVER 37 Missense_Mutation SNP A G uc001kdy.2 BMPR1A_uc001kdz... Hybrid_Cap... view
C1ORF86 1 2116330 2116330 C3A_LIVER 37 3'UTR SNP C A uc001aix.1 PRKCZ_uc001aiq.... Hybrid_Cap... view
CACNB2 10 18828721 18828722 C3A_LIVER 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDC73 1 193091171 193091171 C3A_LIVER 37 5'UTR SNP C T uc001gtb.2 Hybrid_Cap... view
CDH2 p.R748G 18 25563015 25563015 C3A_LIVER 37 Missense_Mutation SNP G C uc002kwg.2 CDH2_uc010xbn.1... Hybrid_Cap... view
CDK11B 1 1654066 1654068 C3A_LIVER 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CDK18 1 205495890 205495891 C3A_LIVER 37 Intron Del CT - uc001hcr.2 CDK18_uc010pri.... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 C3A_LIVER 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 p.D291Y 3 1363443 1363443 C3A_LIVER 37 Missense_Mutation SNP G T uc003boz.2 CNTN6_uc011asj.... Hybrid_Cap... view
COL14A1 p.S1734Y 8 121381614 121381614 C3A_LIVER 37 Missense_Mutation SNP C A uc003yox.2 COL14A1_uc003yo... Hybrid_Cap... view
CUBN p.S3050N 10 16916460 16916460 C3A_LIVER 37 Missense_Mutation SNP C T uc001ioo.2 CUBN_uc009xjq.1... Hybrid_Cap... view
DNAH8 6 38952247 38952250 C3A_LIVER 37 Intron Del CACA - uc003ooe.1 DNAH8_uc003oog.... Hybrid_Cap...
DVL1 p.R27C 1 1284367 1284367 C3A_LIVER 37 Missense_Mutation SNP G A uc001aer.3 Hybrid_Cap... view
EIF4B p.R251G 12 53421649 53421649 C3A_LIVER 37 Missense_Mutation SNP C G uc010snu.1 EIF4B_uc009zmp.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 C3A_LIVER 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ETV1 7 14028708 14028708 C3A_LIVER 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FANCI 15 89859932 89859933 C3A_LIVER 37 3'UTR Ins - C rs71672837 uc010bnp.1 FANCI_uc002bnm.... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 C3A_LIVER 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 C3A_LIVER 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 C3A_LIVER 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FMO4 p.W490* 1 171310770 171310770 C3A_LIVER 37 Nonsense_Mutation SNP G A uc001gho.2 Hybrid_Cap... view
FN1 2 216244182 216244185 C3A_LIVER 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 C3A_LIVER 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 C3A_LIVER 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 C3A_LIVER 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 C3A_LIVER 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HSP90B1 p.E791del 12 104341188 104341190 C3A_LIVER 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 C3A_LIVER 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INHBA 7 41729121 41729122 C3A_LIVER 37 3'UTR Ins - T uc003thq.2 INHBA_uc003thr.... Hybrid_Cap...
INSRR p.T107M 1 156823861 156823861 C3A_LIVER 37 Missense_Mutation SNP G A uc010pht.1 NTRK1_uc001fqf.... Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 C3A_LIVER 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KDSR p.R236* 18 61006104 61006104 C3A_LIVER 37 Nonsense_Mutation SNP G A uc010dpw.2 KDSR_uc010xem.1... Hybrid_Cap... view
KLK7 19 51480672 51480675 C3A_LIVER 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KRAS 12 25398327 25398327 C3A_LIVER 37 5'UTR SNP G A uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
LAMP1 p.R409S 13 113976709 113976709 C3A_LIVER 37 Missense_Mutation SNP G C uc001vtm.1 LAMP1_uc010tka.... Hybrid_Cap... view
LATS2 13 21620222 21620223 C3A_LIVER 37 5'UTR Ins - A rs61240127;rs115723063 uc009zzs.2 LATS2_uc001unr.... Hybrid_Cap...
LIMK1 p.G480R 7 73530159 73530159 C3A_LIVER 37 Missense_Mutation SNP G A uc003uaa.1 RFC2_uc011kfa.1... Hybrid_Cap... view
LRP2 p.E4270K 2 170003252 170003252 C3A_LIVER 37 Missense_Mutation SNP C T uc002ues.2 Hybrid_Cap... view
MAF 16 79628537 79628537 C3A_LIVER 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAMDC4 p.P1130L 9 139755030 139755030 C3A_LIVER 37 Missense_Mutation SNP C T uc004cjs.2 MAMDC4_uc011mej... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 C3A_LIVER 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 C3A_LIVER 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K13 p.G693S 3 185191196 185191196 C3A_LIVER 37 Missense_Mutation SNP G A uc010hyf.2 MAP3K13_uc011br... Hybrid_Cap... view
MAP3K14 p.R218_splice 17 43364293 43364294 C3A_LIVER 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP4K3 p.P772S 2 39485723 39485723 C3A_LIVER 37 Missense_Mutation SNP G A uc002rro.2 MAP4K3_uc002rrp... Hybrid_Cap... view
MAPK10 p.F318Y 4 86988958 86988958 C3A_LIVER 37 Missense_Mutation SNP A T uc003hpq.2 MAPK10_uc010ikg... Hybrid_Cap... view
MAPK4 p.S265R 18 48248409 48248409 C3A_LIVER 37 Missense_Mutation SNP A C uc002lev.2 MAPK4_uc010xdm.... Hybrid_Cap... view
MET p.S244Y 7 116339869 116339869 C3A_LIVER 37 Missense_Mutation SNP C A uc010lkh.2 MET_uc003vij.2_... Hybrid_Cap... view
MLL3 p.Y816fs 7 151945071 151945072 C3A_LIVER 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
MSH3 p.PPA66del 5 79950742 79950750 C3A_LIVER 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MYH9 p.G707D 22 36702015 36702015 C3A_LIVER 37 Missense_Mutation SNP C T uc003apg.2 MYH9_uc003aph.1... Hybrid_Cap... view
NCAM1 11 112832307 112832308 C3A_LIVER 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 C3A_LIVER 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 C3A_LIVER 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 C3A_LIVER 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NIPBL p.V2425M 5 37057297 37057297 C3A_LIVER 37 Missense_Mutation SNP G A uc003jkl.3 NIPBL_uc003jkk.... Hybrid_Cap... view
NOVA1 14 26939424 26939424 C3A_LIVER 37 Intron SNP C G uc001wpy.2 NOVA1_uc001wpz.... Hybrid_Cap... view
NPM1 5 170837734 170837734 C3A_LIVER 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 C3A_LIVER 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NPRL2 3 50384978 50384978 C3A_LIVER 37 3'UTR Del C - rs75013672 uc003daj.1 ZMYND10_uc003da... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 C3A_LIVER 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NRAS p.Q61L 1 115256529 115256529 C3A_LIVER 37 Missense_Mutation SNP T A rs11554290 uc009wgu.2 Hybrid_Cap... view
PAX3 2 223066017 223066018 C3A_LIVER 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 C3A_LIVER 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PCM1 8 17885407 17885408 C3A_LIVER 37 3'UTR Ins - T rs117750062 uc003wyi.3 PCM1_uc011kyh.1... Hybrid_Cap...
PDE4DIP 1 144892109 144892109 C3A_LIVER 37 Intron SNP C T uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PDGFRA 4 55131002 55131002 C3A_LIVER 37 Intron Del A - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PGR 11 100933598 100933599 C3A_LIVER 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PPP2CA 5 133561635 133561635 C3A_LIVER 37 5'UTR SNP G T uc003kze.2 CDKL3_uc011cxm.... Hybrid_Cap... view
PREX2 p.L50V 8 68930087 68930087 C3A_LIVER 37 Missense_Mutation SNP T G uc003xxv.1 PREX2_uc003xxu.... Hybrid_Cap... view
PRKCE 2 45879188 45879188 C3A_LIVER 37 5'UTR SNP C T uc002rut.2 Hybrid_Cap... view
RBL1 p.C807Y 20 35651192 35651192 C3A_LIVER 37 Missense_Mutation SNP C T uc002xgi.2 RBL1_uc010zvt.1... Hybrid_Cap... view
RBL1 20 35724337 35724337 C3A_LIVER 37 5'UTR SNP C T uc002xgi.2 RBL1_uc010zvt.1... Hybrid_Cap... view
RCBTB2 13 49064052 49064052 C3A_LIVER 37 3'UTR SNP C A uc010tgg.1 RCBTB2_uc001vcg... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 C3A_LIVER 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RECQL4 p.A413R 8 145741168 145741169 C3A_LIVER 37 Missense_Mutation DNP GC CT uc003zdj.2 LRRC14_uc003zdk... Hybrid_Cap...
RET p.D567N 10 43608351 43608351 C3A_LIVER 37 Missense_Mutation SNP G A uc001jal.2 RET_uc001jak.1_... Hybrid_Cap... view
ROBO2 3 77666937 77666937 C3A_LIVER 37 Intron Del A - rs78745603 uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap...
SORL1 11 121500400 121500401 C3A_LIVER 37 3'UTR Ins - A rs73020651 uc001pxx.2 SORL1_uc010rzp.... Hybrid_Cap...
SSU72 1 1477324 1477325 C3A_LIVER 37 3'UTR Del CA - rs72502747 uc001agd.2 C1orf70_uc009vk... Hybrid_Cap...
STK31 7 23872024 23872025 C3A_LIVER 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TEC 4 48139307 48139310 C3A_LIVER 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TFEB p.E8K 6 41658972 41658972 C3A_LIVER 37 Missense_Mutation SNP C T uc003oqu.1 TFEB_uc003oqs.1... Hybrid_Cap... view
TGS1 p.V715_splice 8 56723438 56723438 C3A_LIVER 37 Splice_Site_SNP SNP A G uc003xsj.3 TGS1_uc010lyh.2... Hybrid_Cap... view
TNFSF11 p.R284Q 13 43180951 43180951 C3A_LIVER 37 Missense_Mutation SNP G A rs61761332 uc001uyu.2 TNFSF11_uc001uy... Hybrid_Cap... view
TRPS1 8 116635872 116635873 C3A_LIVER 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTBK1 p.E771del 6 43250726 43250728 C3A_LIVER 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
TTN p.F6290L 2 179586788 179586788 C3A_LIVER 37 Missense_Mutation SNP A C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN 2 179611154 179611154 C3A_LIVER 37 Intron SNP C A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN 2 179622616 179622616 C3A_LIVER 37 Intron SNP G T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
UBE3B 12 109947357 109947358 C3A_LIVER 37 Intron Ins - T uc001top.2 UBE3B_uc001toq.... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 C3A_LIVER 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...