Annotation Summary for Cell Line: CAL-33  

Cell line primary name: CAL-33
Cell line aliases:
Gender: M
Site Primary: upper_aerodigestive_tract
Histology: carcinoma
Hist Subtype1: squamous_cell_carcinoma
Notes:
Source: DSMZ
Expression arrays: GAZER_p_NCLE_Expr_P13_HG-U133_Plus_2_B05_779738
SNP arrays: AWASH_p_NCLE_DNAAffy10_GenomeWideSNP_6_A09_542966
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in CAL-33

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ACACA 17 35766564 35766564 CAL33_UPPER_AER... 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ACACB p.E1575K 12 109677695 109677695 CAL33_UPPER_AER... 37 Missense_Mutation SNP G A uc001tob.2 ACACB_uc001toc.... Hybrid_Cap... view
ADAM17 2 9630245 9630245 CAL33_UPPER_AER... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM17 p.G242E 2 9666268 9666268 CAL33_UPPER_AER... 37 Missense_Mutation SNP C T uc002qzu.2 ADAM17_uc010ewy... Hybrid_Cap... view
ADAM28 8 24211994 24211997 CAL33_UPPER_AER... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 CAL33_UPPER_AER... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 CAL33_UPPER_AER... 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
APC p.N1118K 5 112174645 112174645 CAL33_UPPER_AER... 37 Missense_Mutation SNP T A uc010jby.2 APC_uc011cvt.1_... Hybrid_Cap... view
BAX 19 49464508 49464508 CAL33_UPPER_AER... 37 3'UTR Del T - uc002plf.1 BAX_uc002plg.1_... Hybrid_Cap...
BCL3 19 45262965 45262967 CAL33_UPPER_AER... 37 3'UTR Del CCC - uc010xxe.1 Hybrid_Cap...
BIK p.G153E 22 43525286 43525286 CAL33_UPPER_AER... 37 Missense_Mutation SNP G A uc003bdk.2 Hybrid_Cap... view
BIRC5 17 76219784 76219785 CAL33_UPPER_AER... 37 3'UTR Ins - AA uc002jvf.2 BIRC5_uc002jvg.... Hybrid_Cap...
BMP2K p.QQQQ482del 4 79792137 79792148 CAL33_UPPER_AER... 37 In_Frame_Del Del CAGCA... - rs17855588 uc003hlk.2 BMP2K_uc010ijl.... Hybrid_Cap...
BRD2 6 32948599 32948599 CAL33_UPPER_AER... 37 3'UTR Del C - uc010juh.2 BRD2_uc003ocn.3... Hybrid_Cap...
CACNB2 10 18828721 18828722 CAL33_UPPER_AER... 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CAD p.N154S 2 27445170 27445170 CAL33_UPPER_AER... 37 Missense_Mutation SNP A G uc002rji.2 CAD_uc010eyw.2_... Hybrid_Cap... view
CASK p.M122L X 41598702 41598702 CAL33_UPPER_AER... 37 Missense_Mutation SNP T A uc004dfl.3 CASK_uc004dfm.3... Hybrid_Cap... view
CASP8 p.R472* 2 202149973 202149973 CAL33_UPPER_AER... 37 Nonsense_Mutation SNP C T uc002uxt.1 CASP8_uc002uxp.... Hybrid_Cap... view
CDK11B 1 1654066 1654068 CAL33_UPPER_AER... 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CHD1 p.P1684del 5 98192165 98192167 CAL33_UPPER_AER... 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CIT p.V2053M 12 120127985 120127985 CAL33_UPPER_AER... 37 Missense_Mutation SNP C T uc001txj.1 CIT_uc001txh.1_... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 CAL33_UPPER_AER... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 CAL33_UPPER_AER... 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
COL18A1 p.GPP1406del 21 46925141 46925149 CAL33_UPPER_AER... 37 In_Frame_Del Del GGCCC... - uc011afs.1 COL18A1_uc002zh... Hybrid_Cap...
CSNK1D p.R160S 17 80210979 80210979 CAL33_UPPER_AER... 37 Missense_Mutation SNP G T uc002kef.2 SLC16A3_uc002ke... Hybrid_Cap... view
CYP17A1 10 104590394 104590394 CAL33_UPPER_AER... 37 3'UTR SNP G T uc001kwg.2 C10orf26_uc009x... Hybrid_Cap... view
CYP1B1 2 38297654 38297655 CAL33_UPPER_AER... 37 3'UTR Ins - A rs9341258 uc002rqo.2 Hybrid_Cap...
DFNA5 7 24783982 24783982 CAL33_UPPER_AER... 37 Intron Del C - uc010kus.1 DFNA5_uc003swz.... Hybrid_Cap...
DST 6 56483176 56483176 CAL33_UPPER_AER... 37 Intron SNP C T uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
DYRK1A 21 38884966 38884967 CAL33_UPPER_AER... 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EIF2AK1 p.K400M 7 6078223 6078223 CAL33_UPPER_AER... 37 Missense_Mutation SNP T A uc003spp.2 EIF2AK1_uc003sp... Hybrid_Cap... view
EP300 22 41574970 41574972 CAL33_UPPER_AER... 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 CAL33_UPPER_AER... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ERG p.I402N 21 39755581 39755581 CAL33_UPPER_AER... 37 Missense_Mutation SNP A T uc010gnw.2 ERG_uc002yxa.2_... Hybrid_Cap... view
EXT1 8 118811807 118811807 CAL33_UPPER_AER... 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
FGFR1OP 6 167453519 167453520 CAL33_UPPER_AER... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 CAL33_UPPER_AER... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 CAL33_UPPER_AER... 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 CAL33_UPPER_AER... 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 CAL33_UPPER_AER... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRK7 p.T262N 3 141499388 141499388 CAL33_UPPER_AER... 37 Missense_Mutation SNP C A uc011bnd.1 Hybrid_Cap... view
GUCY2C 12 14827464 14827466 CAL33_UPPER_AER... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HNF1A 12 121434630 121434631 CAL33_UPPER_AER... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HNRNPH1 5 179050268 179050268 CAL33_UPPER_AER... 37 Intron SNP G A uc003mkf.3 HNRNPH1_uc003mk... Hybrid_Cap... view
HSP90B1 p.D368G 12 104335198 104335198 CAL33_UPPER_AER... 37 Missense_Mutation SNP A G uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap... view
ILK 11 6630029 6630029 CAL33_UPPER_AER... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INSRR p.W728R 1 156815198 156815198 CAL33_UPPER_AER... 37 Missense_Mutation SNP A G uc010pht.1 NTRK1_uc001fqf.... Hybrid_Cap... view
ITGAV p.G211_splice 2 187498103 187498103 CAL33_UPPER_AER... 37 Splice_Site_SNP SNP T C uc002upq.2 ITGAV_uc010frs.... Hybrid_Cap... view
ITGB1 10 33197131 33197134 CAL33_UPPER_AER... 37 Intron Del CTTT - rs116966876 uc001iwq.3 ITGB1_uc001iwp.... Hybrid_Cap...
LRP6 12 12274019 12274019 CAL33_UPPER_AER... 37 3'UTR SNP C T uc001rah.3 BCL2L14_uc001ra... Hybrid_Cap... view
MAF 16 79628537 79628537 CAL33_UPPER_AER... 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML1 5 179202079 179202079 CAL33_UPPER_AER... 37 3'UTR Del C - uc003mkm.2 MAML1_uc003mkn.... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 CAL33_UPPER_AER... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 CAL33_UPPER_AER... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 CAL33_UPPER_AER... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPKAPK3 3 50685575 50685575 CAL33_UPPER_AER... 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MAST4 p.K1269R 5 66459380 66459380 CAL33_UPPER_AER... 37 Missense_Mutation SNP A G uc003jut.1 MAST4_uc003juw.... Hybrid_Cap... view
MASTL p.A349P 10 27458933 27458933 CAL33_UPPER_AER... 37 Missense_Mutation SNP G C uc001itm.2 MASTL_uc001itl.... Hybrid_Cap... view
MED13L p.D714E 12 116445312 116445312 CAL33_UPPER_AER... 37 Missense_Mutation SNP G C uc001tvw.2 Hybrid_Cap... view
MLL p.A1286A 11 118352653 118352653 CAL33_UPPER_AER... 37 Silent SNP C T uc001ptb.2 MLL_uc001pta.2_... Hybrid_Cap... view
MLLT10 p.R704fs 10 22016857 22016857 CAL33_UPPER_AER... 37 Frame_Shift_Del Del G - uc001iqs.2 MLLT10_uc001iqt... Hybrid_Cap...
MMP8 11 102584030 102584030 CAL33_UPPER_AER... 37 3'UTR SNP A G uc001phe.2 MMP8_uc010rut.1... Hybrid_Cap... view
MSH3 p.L1006fs 5 80160647 80160648 CAL33_UPPER_AER... 37 Frame_Shift_Del Del CT - uc003kgz.2 Hybrid_Cap...
MSH5 p.P181R 6 31711920 31711920 CAL33_UPPER_AER... 37 Missense_Mutation SNP C G uc003nwt.1 MSH5_uc003nwu.1... Hybrid_Cap... view
MTMR11 1 149900897 149900897 CAL33_UPPER_AER... 37 3'UTR SNP G C uc001etl.3 SF3B4_uc001eti.... Hybrid_Cap... view
MYLK p.V1522A 3 123366125 123366125 CAL33_UPPER_AER... 37 Missense_Mutation SNP A G uc003ego.2 MYLK_uc010hrr.2... Hybrid_Cap... view
MYLK p.E1430_splice 3 123368043 123368044 CAL33_UPPER_AER... 37 Splice_Site_Ins Ins - G rs41431347 uc003ego.2 MYLK_uc010hrr.2... Hybrid_Cap...
MYST2 17 47904897 47904897 CAL33_UPPER_AER... 37 3'UTR SNP G A uc002ipm.2 MYST2_uc010wma.... Hybrid_Cap... view
MYST4 p.E1104del 10 76781906 76781908 CAL33_UPPER_AER... 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NCAM1 11 112832307 112832308 CAL33_UPPER_AER... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 CAL33_UPPER_AER... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.QQQ1272del 20 46279815 46279823 CAL33_UPPER_AER... 37 In_Frame_Del Del GCAGC... - uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 CAL33_UPPER_AER... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NEK9 14 75572824 75572824 CAL33_UPPER_AER... 37 Intron SNP C T uc001xrl.2 NEK9_uc001xrk.2... Hybrid_Cap... view
NPR1 1 153665919 153665920 CAL33_UPPER_AER... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 CAL33_UPPER_AER... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
OBSCN p.W3833* 1 228482583 228482583 CAL33_UPPER_AER... 37 Nonsense_Mutation SNP G A uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
PAX3 2 223158653 223158653 CAL33_UPPER_AER... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX5 9 37034103 37034104 CAL33_UPPER_AER... 37 5'UTR Ins - TC rs112221838 uc003zzo.1 PAX5_uc011lpw.1... Hybrid_Cap...
PCDH15 10 55581364 55581364 CAL33_UPPER_AER... 37 3'UTR SNP A C uc010qhy.1 PCDH15_uc010qhq... Hybrid_Cap... view
PDE4DIP p.E139K 1 144952304 144952304 CAL33_UPPER_AER... 37 Missense_Mutation SNP C T uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PDGFB 22 39640018 39640018 CAL33_UPPER_AER... 37 5'UTR SNP C T uc003axf.2 Hybrid_Cap... view
PDK4 7 95214899 95214899 CAL33_UPPER_AER... 37 3'UTR SNP G A uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap... view
PGR 11 100933598 100933599 CAL33_UPPER_AER... 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3CA p.H1047R 3 178952085 178952085 CAL33_UPPER_AER... 37 Missense_Mutation SNP A G uc003fjk.2 Hybrid_Cap... view
PRKCE p.D505N 2 46313422 46313422 CAL33_UPPER_AER... 37 Missense_Mutation SNP G A uc002rut.2 Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 CAL33_UPPER_AER... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTCH1 p.F1207F 9 98211534 98211534 CAL33_UPPER_AER... 37 Silent SNP G A uc004avk.3 PTCH1_uc010mrn.... Hybrid_Cap... view
RAC1 7 6442142 6442143 CAL33_UPPER_AER... 37 3'UTR Del AC - rs59685280;rs2303366 uc003spw.2 RAC1_uc003spx.2... Hybrid_Cap...
RAPGEF2 4 160189200 160189201 CAL33_UPPER_AER... 37 5'UTR Ins - T rs72011511 uc003iqg.3 Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 CAL33_UPPER_AER... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RNASEL p.A66T 1 182555746 182555746 CAL33_UPPER_AER... 37 Missense_Mutation SNP C T uc001gpj.1 RNASEL_uc009wxz... Hybrid_Cap... view
RPS6KA1 p.A178V 1 26879919 26879920 CAL33_UPPER_AER... 37 Missense_Mutation DNP CT TC rs4970490 uc001bms.1 RPS6KA1_uc001bm... Hybrid_Cap...
SCARA5 8 27729298 27729298 CAL33_UPPER_AER... 37 3'UTR SNP G C uc003xgj.2 SCARA5_uc010luz... Hybrid_Cap... view
SMAD4 p.Q256* 18 48584593 48584593 CAL33_UPPER_AER... 37 Nonsense_Mutation SNP C T uc010xdp.1 SMAD4_uc010xdo.... Hybrid_Cap... view
SMC2 p.A385S 9 106873994 106873994 CAL33_UPPER_AER... 37 Missense_Mutation SNP G T uc004bbv.2 SMC2_uc004bbu.1... Hybrid_Cap... view
STK31 7 23872024 23872025 CAL33_UPPER_AER... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TEC 4 48139307 48139310 CAL33_UPPER_AER... 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TESK2 1 45810378 45810378 CAL33_UPPER_AER... 37 3'UTR SNP C A uc001cns.1 TESK2_uc009vxr.... Hybrid_Cap... view
TESK2 1 45810380 45810380 CAL33_UPPER_AER... 37 3'UTR SNP A G uc001cns.1 TESK2_uc009vxr.... Hybrid_Cap... view
TLK1 2 171902652 171902652 CAL33_UPPER_AER... 37 Intron SNP T G uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap... view
TMEM123 11 102269398 102269398 CAL33_UPPER_AER... 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.R175H 17 7578406 7578406 CAL33_UPPER_AER... 37 Missense_Mutation SNP C T rs28934578 uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 CAL33_UPPER_AER... 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIM33 1 114940215 114940216 CAL33_UPPER_AER... 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRIO p.L853del 5 14364002 14364004 CAL33_UPPER_AER... 37 In_Frame_Del Del TCT - uc003jff.2 TRIO_uc003jfg.2... Hybrid_Cap...
TRPS1 8 116635872 116635873 CAL33_UPPER_AER... 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TSC2 16 2138671 2138672 CAL33_UPPER_AER... 37 3'UTR Del AA - uc002con.2 TSC2_uc010bsd.2... Hybrid_Cap...
TTN p.N25204I 2 179427544 179427544 CAL33_UPPER_AER... 37 Missense_Mutation SNP T A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.R19706C 2 179445286 179445286 CAL33_UPPER_AER... 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
UBR5 p.H1013P 8 103312296 103312296 CAL33_UPPER_AER... 37 Missense_Mutation SNP T G uc003ykr.1 UBR5_uc003yks.1... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 CAL33_UPPER_AER... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WEE1 11 9610239 9610239 CAL33_UPPER_AER... 37 3'UTR SNP C T uc001mhs.2 WEE1_uc001mht.2... Hybrid_Cap... view
ZAP70 p.S497L 2 98354227 98354227 CAL33_UPPER_AER... 37 Missense_Mutation SNP C T uc002syd.1 ZAP70_uc002sye.... Hybrid_Cap... view