Annotation Summary for Cell Line: CAL-62  

Cell line primary name: CAL-62
Cell line aliases:
Gender: F
Site Primary: thyroid
Histology: carcinoma
Hist Subtype1: anaplastic_carcinoma
Notes:
Source: DSMZ
Expression arrays: WATCH_p_NCLE_RNA8_HG-U133_Plus_2_E01_474604
SNP arrays: CHARY_p_NCLE_DNAAffy9_GenomeWideSNP_6_H01_490514
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in CAL-62

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM28 8 24211994 24211997 CAL62_THYROID 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 CAL62_THYROID 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 CAL62_THYROID 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
AR p.F827L X 66942700 66942700 CAL62_THYROID 37 Missense_Mutation SNP C A uc004dwu.1 AR_uc004dwv.1_M... Hybrid_Cap... view
ASPH p.A264_splice 8 62550924 62550925 CAL62_THYROID 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
BTG1 12 92537706 92537707 CAL62_THYROID 37 3'UTR Ins - T rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
C17ORF37 17 37885533 37885533 CAL62_THYROID 37 3'UTR SNP C T uc002hsq.2 Hybrid_Cap... view
CACNB2 10 18828721 18828722 CAL62_THYROID 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDC25C p.K218E 5 137661545 137661545 CAL62_THYROID 37 Missense_Mutation SNP T C uc003lcs.1 CDC25C_uc003lcp... Hybrid_Cap... view
CDK11B 1 1654066 1654068 CAL62_THYROID 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CHD1 p.P1684del 5 98192165 98192167 CAL62_THYROID 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 CAL62_THYROID 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CLTCL1 22 19196673 19196674 CAL62_THYROID 37 Intron Ins - A uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 CAL62_THYROID 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CREBBP p.E1541* 16 3786144 3786144 CAL62_THYROID 37 Nonsense_Mutation SNP C A uc002cvv.2 CREBBP_uc002cvw... Hybrid_Cap... view
CXCL12 10 44873992 44873993 CAL62_THYROID 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
DST p.K2455_splice 6 56434811 56434811 CAL62_THYROID 37 Splice_Site_SNP SNP C A uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
DVL1 p.R164G 1 1277162 1277162 CAL62_THYROID 37 Missense_Mutation SNP T C uc001aer.3 DVL1_uc002quu.2... Hybrid_Cap... view
EP300 p.D1485fs 22 41568504 41568504 CAL62_THYROID 37 Frame_Shift_Del Del A - uc003azl.3 Hybrid_Cap...
EP300 22 41574970 41574972 CAL62_THYROID 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA3 p.N232D 3 89259550 89259550 CAL62_THYROID 37 Missense_Mutation SNP A G uc003dqy.2 EPHA3_uc003dqx.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 CAL62_THYROID 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ETV1 7 14028708 14028708 CAL62_THYROID 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FLI1 11 128638217 128638217 CAL62_THYROID 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLT4 p.T1254I 5 180036951 180036951 CAL62_THYROID 37 Missense_Mutation SNP G A uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap... view
FN1 2 216244182 216244185 CAL62_THYROID 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GLTSCR1 p.D905N 19 48197801 48197801 CAL62_THYROID 37 Missense_Mutation SNP G A uc002phh.3 GLTSCR1_uc002ph... Hybrid_Cap... view
GPR87 p.S329T 3 151012049 151012049 CAL62_THYROID 37 Missense_Mutation SNP A T rs71796305 uc003eyt.2 MED12L_uc011bnz... Hybrid_Cap... view
GRIA3 X 122318386 122318387 CAL62_THYROID 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
HNF1A 12 121434630 121434631 CAL62_THYROID 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
IL1RN 2 113890607 113890609 CAL62_THYROID 37 3'UTR Del CCT - uc002tiz.2 IL1RN_uc002tix.... Hybrid_Cap...
ILK 11 6630029 6630029 CAL62_THYROID 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INHBA p.R309W 7 41729604 41729604 CAL62_THYROID 37 Missense_Mutation SNP G A uc003thq.2 INHBA_uc003thr.... Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 CAL62_THYROID 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KLF6 p.W239fs 10 3822362 3822381 CAL62_THYROID 37 Frame_Shift_Del Del CATCA... - uc001iha.2 KLF6_uc010qaj.1... Hybrid_Cap...
KLK7 19 51480672 51480675 CAL62_THYROID 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KRAS p.G12R 12 25398285 25398285 CAL62_THYROID 37 Missense_Mutation SNP C G uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
LRRK2 p.T149S 12 40631780 40631780 CAL62_THYROID 37 Missense_Mutation SNP C G uc001rmg.3 Hybrid_Cap... view
MAF 16 79628325 79628325 CAL62_THYROID 37 3'UTR Del A - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 CAL62_THYROID 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 CAL62_THYROID 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 CAL62_THYROID 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MEF2A p.M251I 15 100230522 100230522 CAL62_THYROID 37 Missense_Mutation SNP G A uc010urw.1 MEF2A_uc010urv.... Hybrid_Cap... view
MERTK p.E540Q 2 112758791 112758791 CAL62_THYROID 37 Missense_Mutation SNP G C rs113485015 uc002thk.1 MERTK_uc002thl.... Hybrid_Cap... view
MGA p.R866* 15 42003059 42003059 CAL62_THYROID 37 Nonsense_Mutation SNP C T uc010ucy.1 MGA_uc001zog.1_... Hybrid_Cap... view
MLLT10 p.Q248* 10 21940644 21940644 CAL62_THYROID 37 Nonsense_Mutation SNP C T uc001iqs.2 MLLT10_uc001iqt... Hybrid_Cap... view
NCAM1 11 112832307 112832308 CAL62_THYROID 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 CAL62_THYROID 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 CAL62_THYROID 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NEK9 14 75573065 75573065 CAL62_THYROID 37 Intron Del A - uc001xrl.2 NEK9_uc001xrk.2... Hybrid_Cap...
NF2 p.E215* 22 30054221 30054221 CAL62_THYROID 37 Nonsense_Mutation SNP G T uc003age.3 NF2_uc003afy.3_... Hybrid_Cap... view
NFIA 1 61921185 61921186 CAL62_THYROID 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NFKB1 p.D917_splice 4 103534740 103534741 CAL62_THYROID 37 Splice_Site_Ins Ins - A rs35795162 uc011cep.1 NFKB1_uc011ceq.... Hybrid_Cap...
NPR1 1 153665919 153665920 CAL62_THYROID 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 CAL62_THYROID 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PAX3 2 223158653 223158653 CAL62_THYROID 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP p.Q1665fs 1 144873963 144873963 CAL62_THYROID 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.V486fs 1 144917828 144917828 CAL62_THYROID 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PGGT1B 5 114548071 114548072 CAL62_THYROID 37 3'UTR Ins - C uc003kqw.3 PGGT1B_uc003kqx... Hybrid_Cap...
PGR 11 100933598 100933599 CAL62_THYROID 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PRKD1 14 30046424 30046424 CAL62_THYROID 37 3'UTR SNP C T uc001wqh.2 Hybrid_Cap... view
PRKDC p.G1599S 8 48794640 48794640 CAL62_THYROID 37 Missense_Mutation SNP C T uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 CAL62_THYROID 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 CAL62_THYROID 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
SLC6A8 X 152957656 152957657 CAL62_THYROID 37 Intron Ins - A uc004fib.3 SLC6A8_uc004fic... Hybrid_Cap...
STAG3 p.E466fs 7 99796511 99796515 CAL62_THYROID 37 Frame_Shift_Del Del GCAAC - uc003utx.1 STAG3_uc010lgs.... Hybrid_Cap...
TGFB2 1 218519928 218519929 CAL62_THYROID 37 5'UTR Ins - AAAC uc001hln.2 TGFB2_uc001hll.... Hybrid_Cap...
THRAP3 p.Y476C 1 36755047 36755047 CAL62_THYROID 37 Missense_Mutation SNP A G uc001cae.3 THRAP3_uc001caf... Hybrid_Cap... view
TLE1 9 84202837 84202838 CAL62_THYROID 37 Intron Ins - TGTCATCCCGCC rs5898748 uc004alz.2 TLE1_uc004aly.2... Hybrid_Cap...
TMEM123 11 102269461 102269461 CAL62_THYROID 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.A161D 17 7578448 7578448 CAL62_THYROID 37 Missense_Mutation SNP G T uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 CAL62_THYROID 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRPM8 2 234851403 234851403 CAL62_THYROID 37 Intron SNP G A uc002vvh.2 TRPM8_uc010fyj.... Hybrid_Cap... view
TRPM8 p.P958T 2 234894442 234894442 CAL62_THYROID 37 Missense_Mutation SNP C A uc002vvh.2 TRPM8_uc010fyj.... Hybrid_Cap... view
TRPS1 8 116635872 116635873 CAL62_THYROID 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 CAL62_THYROID 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...