Annotation Summary for Cell Line: CAS-1  

Cell line primary name: CAS-1
Cell line aliases:
Gender: M
Site Primary: central_nervous_system
Histology: glioma
Hist Subtype1: astrocytoma_Grade_IV
Notes:
Source: ICLC
Expression arrays: BUNDS_p_NCLE_RNA5_HG-U133_Plus_2_H09_419838
SNP arrays: FIEFS_p_NCLE_DNA_Affy5_GenomeWideSNP_6_E02_411008
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in CAS-1

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ACACA 17 35766564 35766564 CAS1_CENTRAL_NE... 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM17 2 9630245 9630245 CAS1_CENTRAL_NE... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 CAS1_CENTRAL_NE... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS18 16 77326943 77326943 CAS1_CENTRAL_NE... 37 Intron SNP C A uc002ffc.3 ADAMTS18_uc010c... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 CAS1_CENTRAL_NE... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 CAS1_CENTRAL_NE... 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 CAS1_CENTRAL_NE... 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
BIRC6 2 32843085 32843085 CAS1_CENTRAL_NE... 37 3'UTR SNP T C uc010ezu.2 Hybrid_Cap... view
BMP4 14 54416601 54416602 CAS1_CENTRAL_NE... 37 3'UTR Ins - A rs74495140;rs76335800 uc001xal.3 BMP4_uc010aoh.2... Hybrid_Cap...
CACNB2 10 18828721 18828722 CAS1_CENTRAL_NE... 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CAMK1D p.A83V 10 12708758 12708758 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP C T uc001ilo.2 CAMK1D_uc001iln... Hybrid_Cap... view
CDK11B 1 1654066 1654068 CAS1_CENTRAL_NE... 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 CAS1_CENTRAL_NE... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CSPG4 p.G150D 15 75982957 75982957 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP C T uc002baw.2 Hybrid_Cap... view
CTBP2 p.K974fs 10 126678123 126678123 CAS1_CENTRAL_NE... 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
DNAH8 p.A4024T 6 38942192 38942192 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP G A uc003ooe.1 DNAH8_uc003oog.... Hybrid_Cap... view
DNAH8 6 38952247 38952250 CAS1_CENTRAL_NE... 37 Intron Del CACA - uc003ooe.1 DNAH8_uc003oog.... Hybrid_Cap...
DYRK1A 21 38884966 38884967 CAS1_CENTRAL_NE... 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EIF4B 12 53400266 53400266 CAS1_CENTRAL_NE... 37 5'UTR SNP A G uc010snu.1 EIF4B_uc009zmp.... Hybrid_Cap... view
EP300 22 41574970 41574972 CAS1_CENTRAL_NE... 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA5 4 66189753 66189754 CAS1_CENTRAL_NE... 37 3'UTR Ins - T rs67487372 uc011cah.1 EPHA5_uc003hcx.... Hybrid_Cap...
EPHA6 3 97367230 97367231 CAS1_CENTRAL_NE... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 CAS1_CENTRAL_NE... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLT4 5 180035183 180035185 CAS1_CENTRAL_NE... 37 Intron Del AGT - uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap...
FN1 2 216244182 216244185 CAS1_CENTRAL_NE... 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GPR141 p.H19Q 7 37780052 37780052 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP C A uc003tfm.1 Hybrid_Cap... view
GRIA3 X 122318386 122318387 CAS1_CENTRAL_NE... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 CAS1_CENTRAL_NE... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HERC2 p.E1434K 15 28478861 28478861 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP C T uc001zbj.2 Hybrid_Cap... view
HNF1A 12 121434630 121434631 CAS1_CENTRAL_NE... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 CAS1_CENTRAL_NE... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
IRS2 p.C1306W 13 110434483 110434483 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP G C uc001vqv.2 Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 CAS1_CENTRAL_NE... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KDM5A 12 498276 498277 CAS1_CENTRAL_NE... 37 5'UTR Ins - A rs3043226 uc001qif.1 KDM5A_uc001qie.... Hybrid_Cap...
KLK7 19 51480672 51480675 CAS1_CENTRAL_NE... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LRP2 p.L2170Q 2 170063721 170063721 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP A T uc002ues.2 Hybrid_Cap... view
MAF 16 79628537 79628537 CAS1_CENTRAL_NE... 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAF 16 79628325 79628325 CAS1_CENTRAL_NE... 37 3'UTR Del A - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 CAS1_CENTRAL_NE... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 CAS1_CENTRAL_NE... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 CAS1_CENTRAL_NE... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MFSD4 1 205569596 205569596 CAS1_CENTRAL_NE... 37 3'UTR SNP G A uc001hcv.3 MFSD4_uc010prk.... Hybrid_Cap... view
MYLK p.G468D 3 123451856 123451856 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP C T uc003ego.2 MYLK_uc011bjw.1... Hybrid_Cap... view
MYST4 p.1104_1105insE 10 76781905 76781906 CAS1_CENTRAL_NE... 37 In_Frame_Ins Ins - GAA rs111976843 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NACA p.P1225L 12 57111640 57111640 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP G A uc009zoy.1 NACA_uc001slz.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 CAS1_CENTRAL_NE... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 CAS1_CENTRAL_NE... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 CAS1_CENTRAL_NE... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NPM1 5 170837734 170837734 CAS1_CENTRAL_NE... 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 CAS1_CENTRAL_NE... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 CAS1_CENTRAL_NE... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR3C1 5 142659146 142659148 CAS1_CENTRAL_NE... 37 3'UTR Del TTG - uc003lmy.2 NR3C1_uc003lmz.... Hybrid_Cap...
OBSCN p.R3140W 1 228474614 228474614 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP C T uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
ODZ1 p.W1883* X 123525942 123525942 CAS1_CENTRAL_NE... 37 Nonsense_Mutation SNP C T uc010nqy.2 ODZ1_uc011muj.1... Hybrid_Cap... view
PDE4DIP p.Q1665fs 1 144873963 144873963 CAS1_CENTRAL_NE... 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDGFRA 4 55131002 55131002 CAS1_CENTRAL_NE... 37 Intron Del A - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PDK4 7 95221928 95221928 CAS1_CENTRAL_NE... 37 Intron Del A - uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap...
PGGT1B 5 114548071 114548072 CAS1_CENTRAL_NE... 37 3'UTR Ins - C uc003kqw.3 PGGT1B_uc003kqx... Hybrid_Cap...
PHKG2 p.Q277R 16 30767927 30767927 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP A G uc002dzi.1 PHKG2_uc002dzj.... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 CAS1_CENTRAL_NE... 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIP5K1A p.S179I 1 151205076 151205076 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP G T uc001exj.2 PIP5K1A_uc001ex... Hybrid_Cap... view
PKN1 p.A250V 19 14561250 14561250 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP C T uc002myq.2 PKN1_uc002myp.2... Hybrid_Cap... view
PMS2 p.N335S 7 6029571 6029571 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP T C uc003spl.2 PMS2_uc003spj.2... Hybrid_Cap... view
PRAME p.E38A 22 22893420 22893420 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP T G uc002zwf.2 LOC96610_uc011a... Hybrid_Cap... view
PRKCA 17 64298959 64298960 CAS1_CENTRAL_NE... 37 5'UTR Ins - G rs71160558 uc002jfp.1 PRKCA_uc002jfo.... Hybrid_Cap...
PRKD3 2 37480319 37480320 CAS1_CENTRAL_NE... 37 Stop_Codon_Ins Ins - T rs79875666 uc002rqd.2 Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 CAS1_CENTRAL_NE... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTEN p.T286fs 10 89720706 89720706 CAS1_CENTRAL_NE... 37 Frame_Shift_Del Del C - uc001kfb.2 Hybrid_Cap...
RBL1 p.L30M 20 35724244 35724244 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP G T uc002xgi.2 RBL1_uc010zvt.1... Hybrid_Cap... view
RHPN2 19 33470869 33470869 CAS1_CENTRAL_NE... 37 3'UTR SNP T C uc002nuf.2 RHPN2_uc010xro.... Hybrid_Cap... view
RIF1 p.A181T 2 152276741 152276741 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP G A uc002txm.2 RIF1_uc002txl.2... Hybrid_Cap... view
RIOK1 p.L331_splice 6 7404789 7404789 CAS1_CENTRAL_NE... 37 Splice_Site_SNP SNP G A uc003mxn.2 RIOK1_uc003mxo.... Hybrid_Cap... view
RIOK1 p.Q417* 6 7410664 7410664 CAS1_CENTRAL_NE... 37 Nonsense_Mutation SNP C T uc003mxn.2 RIOK1_uc003mxo.... Hybrid_Cap... view
RPS6KA2 6 167275731 167275731 CAS1_CENTRAL_NE... 37 5'UTR SNP C G uc003qvd.1 RPS6KA2_uc003qv... Hybrid_Cap... view
SET p.D223V 9 131456053 131456053 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP A T uc004bvt.3 SET_uc004bvu.3_... Hybrid_Cap... view
SIK1 21 44846060 44846060 CAS1_CENTRAL_NE... 37 5'UTR SNP G A uc002zdf.2 Hybrid_Cap... view
SOX11 p.K88Q 2 5833115 5833115 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP A C uc002qyj.2 Hybrid_Cap... view
STK31 7 23872024 23872025 CAS1_CENTRAL_NE... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TLK1 2 171850178 171850179 CAS1_CENTRAL_NE... 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TMEM123 11 102269398 102269398 CAS1_CENTRAL_NE... 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TOX p.R159G 8 59764301 59764301 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP T C uc003xtw.1 Hybrid_Cap... view
TP53 p.R248W 17 7577539 7577539 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP G A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 CAS1_CENTRAL_NE... 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRPS1 8 116635872 116635873 CAS1_CENTRAL_NE... 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN p.T8924M 2 179566903 179566903 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 CAS1_CENTRAL_NE... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
ZAK p.F253S 2 174074470 174074470 CAS1_CENTRAL_NE... 37 Missense_Mutation SNP T C uc002uhz.2 ZAK_uc002uhx.2_... Hybrid_Cap... view