Annotation Summary for Cell Line: CL-11  

Cell line primary name: CL-11
Cell line aliases:
Gender:
Site Primary: large_intestine
Histology: carcinoma
Hist Subtype1: adenocarcinoma
Notes:
Source: DSMZ
Expression arrays: WATCH_p_NCLE_RNA8_HG-U133_Plus_2_G07_474626
SNP arrays: CHARY_p_NCLE_DNAAffy9_GenomeWideSNP_6_D07_490364
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in CL-11

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM22 p.R565C 7 87778343 87778343 CL11_LARGE_INTE... 37 Missense_Mutation SNP C T uc003ujp.1 ADAM22_uc003ujk... Hybrid_Cap... view
ADAM28 8 24211994 24211997 CL11_LARGE_INTE... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS20 p.R585C 12 43847717 43847717 CL11_LARGE_INTE... 37 Missense_Mutation SNP G A uc010skx.1 Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 CL11_LARGE_INTE... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP12 p.H1627R 6 151674406 151674406 CL11_LARGE_INTE... 37 Missense_Mutation SNP A G uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap... view
AKAP9 p.1335_1336insQ 7 91652178 91652179 CL11_LARGE_INTE... 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 CL11_LARGE_INTE... 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ALS2 2 202566487 202566487 CL11_LARGE_INTE... 37 3'UTR SNP C T uc002uyo.2 ALS2_uc010ftl.2... Hybrid_Cap... view
APC p.S1344* 5 112175322 112175322 CL11_LARGE_INTE... 37 Nonsense_Mutation SNP C A uc010jby.2 APC_uc011cvt.1_... Hybrid_Cap... view
CABC1 1 227171585 227171585 CL11_LARGE_INTE... 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CHD1 p.P1684del 5 98192165 98192167 CL11_LARGE_INTE... 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHD8 14 21853630 21853630 CL11_LARGE_INTE... 37 3'UTR Del T - rs78520772 uc001was.1 CHD8_uc001war.1... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 CL11_LARGE_INTE... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 CL11_LARGE_INTE... 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
DYRK4 p.H343Q 12 4708317 4708317 CL11_LARGE_INTE... 37 Missense_Mutation SNP C G uc009zeh.1 DYRK4_uc001qmx.... Hybrid_Cap... view
EP300 22 41574970 41574972 CL11_LARGE_INTE... 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 CL11_LARGE_INTE... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHB1 p.M447I 3 134873037 134873037 CL11_LARGE_INTE... 37 Missense_Mutation SNP G C uc003eqt.2 EPHB1_uc003equ.... Hybrid_Cap... view
EPHB6 7 142568771 142568771 CL11_LARGE_INTE... 37 3'UTR Del C - uc011kst.1 EPHB6_uc011ksu.... Hybrid_Cap...
ETV1 7 14028708 14028708 CL11_LARGE_INTE... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
ETV5 p.R167G 3 185797883 185797883 CL11_LARGE_INTE... 37 Missense_Mutation SNP T C uc003fpy.2 ETV5_uc003fpz.2... Hybrid_Cap... view
FBXW7 p.R479Q 4 153247366 153247366 CL11_LARGE_INTE... 37 Missense_Mutation SNP C T uc003ims.2 FBXW7_uc011cii.... Hybrid_Cap... view
FGFR3 4 1809128 1809129 CL11_LARGE_INTE... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLCN 17 17124804 17124804 CL11_LARGE_INTE... 37 Intron SNP C T uc002gra.3 PLD6_uc010cpn.2... Hybrid_Cap... view
FLI1 11 128638217 128638217 CL11_LARGE_INTE... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FMN2 p.PGAGIPPPPPL1096del 1 240371023 240371055 CL11_LARGE_INTE... 37 In_Frame_Del Del CCCGG... - uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FUS p.S361F 16 31201373 31201373 CL11_LARGE_INTE... 37 Missense_Mutation SNP C T uc002ebi.2 FUS_uc002ebf.2_... Hybrid_Cap... view
GNAS p.R595L 20 57430104 57430104 CL11_LARGE_INTE... 37 Missense_Mutation SNP G T uc002xzw.2 GNAS_uc002xzt.2... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 CL11_LARGE_INTE... 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 CL11_LARGE_INTE... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 CL11_LARGE_INTE... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HEPH p.D1090Y X 65486296 65486296 CL11_LARGE_INTE... 37 Missense_Mutation SNP G T uc011moz.1 HEPH_uc004dwn.2... Hybrid_Cap... view
HNF1A 12 121434630 121434631 CL11_LARGE_INTE... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
IGF1R 15 99192755 99192763 CL11_LARGE_INTE... 37 5'UTR Del TTTTT... - uc002bul.2 IGF1R_uc010urq.... Hybrid_Cap...
ILK 11 6630029 6630029 CL11_LARGE_INTE... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGA7 p.Y530C 12 56090843 56090843 CL11_LARGE_INTE... 37 Missense_Mutation SNP T C uc001shh.2 ITGA7_uc001shg.... Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 CL11_LARGE_INTE... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KLK7 19 51480672 51480675 CL11_LARGE_INTE... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KRAS p.Q61H 12 25380275 25380275 CL11_LARGE_INTE... 37 Missense_Mutation SNP T G rs17851045 uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
KRAS p.V14I 12 25398279 25398279 CL11_LARGE_INTE... 37 Missense_Mutation SNP C T rs104894365 uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 CL11_LARGE_INTE... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 CL11_LARGE_INTE... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K11 11 65365660 65365660 CL11_LARGE_INTE... 37 3'UTR SNP G A uc001oew.2 KCNK7_uc001oeq.... Hybrid_Cap... view
MAP3K14 p.R218_splice 17 43364293 43364294 CL11_LARGE_INTE... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
NCAM1 11 112832307 112832308 CL11_LARGE_INTE... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 CL11_LARGE_INTE... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 CL11_LARGE_INTE... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 CL11_LARGE_INTE... 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR3C1 5 142780419 142780419 CL11_LARGE_INTE... 37 Splice_Site_SNP SNP T A uc003lmy.2 NR3C1_uc003lmz.... Hybrid_Cap... view
PASK p.C687Y 2 242066270 242066270 CL11_LARGE_INTE... 37 Missense_Mutation SNP C T uc010fzl.1 PASK_uc010zol.1... Hybrid_Cap... view
PAX3 2 223158653 223158653 CL11_LARGE_INTE... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 CL11_LARGE_INTE... 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PRKD1 p.H442R 14 30102142 30102142 CL11_LARGE_INTE... 37 Missense_Mutation SNP T C uc001wqh.2 Hybrid_Cap... view
PRKDC p.M2040V 8 48772261 48772261 CL11_LARGE_INTE... 37 Missense_Mutation SNP T C uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 CL11_LARGE_INTE... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG1 10 52751088 52751089 CL11_LARGE_INTE... 37 5'UTR Ins - GCT rs67900156;rs71029335 uc001jjm.2 PRKG1_uc010qhp.... Hybrid_Cap...
PTPRC p.S951L 1 198717248 198717248 CL11_LARGE_INTE... 37 Missense_Mutation SNP C T uc001gur.1 PTPRC_uc001gus.... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 CL11_LARGE_INTE... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RPS6KL1 14 75373626 75373627 CL11_LARGE_INTE... 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SCRIB p.R159Q 8 144895667 144895667 CL11_LARGE_INTE... 37 Missense_Mutation SNP C T uc003yzo.1 SCRIB_uc003yzp.... Hybrid_Cap... view
SMAD2 p.S465N 18 45368208 45368208 CL11_LARGE_INTE... 37 Missense_Mutation SNP C T uc002lcy.2 SMAD2_uc002lcz.... Hybrid_Cap... view
SMAD3 p.R93Q 15 67457304 67457304 CL11_LARGE_INTE... 37 Missense_Mutation SNP G A uc002aqj.2 SMAD3_uc010ujr.... Hybrid_Cap... view
SNX19 p.M149L 11 130785390 130785390 CL11_LARGE_INTE... 37 Missense_Mutation SNP T A uc001qgk.3 SNX19_uc010sce.... Hybrid_Cap... view
SPEN p.S1024A 1 16255805 16255805 CL11_LARGE_INTE... 37 Missense_Mutation SNP T G uc001axk.1 SPEN_uc010obp.1... Hybrid_Cap... view
STK31 7 23872024 23872025 CL11_LARGE_INTE... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TAOK3 12 118588761 118588762 CL11_LARGE_INTE... 37 3'UTR Ins - T rs116872184 uc001twx.2 TAOK3_uc001twv.... Hybrid_Cap...
TEC 4 48139307 48139310 CL11_LARGE_INTE... 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TFG 3 100467409 100467409 CL11_LARGE_INTE... 37 3'UTR SNP A G uc003due.2 TFG_uc003duf.2_... Hybrid_Cap... view
TIAM1 p.T1051M 21 32526584 32526584 CL11_LARGE_INTE... 37 Missense_Mutation SNP G A uc002yow.1 TIAM1_uc011adk.... Hybrid_Cap... view
TIE1 p.L210L 1 43772656 43772656 CL11_LARGE_INTE... 37 Silent SNP C T uc001ciu.2 TIE1_uc010okd.1... Hybrid_Cap... view
TNFRSF10B 8 22880058 22880058 CL11_LARGE_INTE... 37 3'UTR SNP G T uc003xcu.2 TNFRSF10B_uc003... Hybrid_Cap... view
TOP2B 3 25639733 25639734 CL11_LARGE_INTE... 37 3'UTR Ins - AGAC uc003cdj.2 TOP2B_uc011awm.... Hybrid_Cap...
TP53 p.S215N 17 7578205 7578205 CL11_LARGE_INTE... 37 Missense_Mutation SNP C T uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 CL11_LARGE_INTE... 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIM33 1 114940215 114940216 CL11_LARGE_INTE... 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TTN p.T22097M 2 179436865 179436865 CL11_LARGE_INTE... 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 CL11_LARGE_INTE... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...