Annotation Summary for Cell Line: COR-L279  

Cell line primary name: COR-L279
Cell line aliases:
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: small_cell_carcinoma
Notes:
Source: ECACC
Expression arrays: GAZER_p_NCLE_Expr_P13_HG-U133_Plus_2_B07_779750
SNP arrays: AWASH_p_NCLE_DNAAffy10_GenomeWideSNP_6_E10_542926
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in COR-L279

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 CORL279_LUNG 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACACA 17 35766564 35766564 CORL279_LUNG 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM17 2 9630245 9630245 CORL279_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 CORL279_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 CORL279_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK1 4 113347609 113347610 CORL279_LUNG 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ARHGEF10 p.G901E 8 1876597 1876597 CORL279_LUNG 37 Missense_Mutation SNP G A uc003wpr.2 ARHGEF10_uc003w... Hybrid_Cap... view
ATIC p.G439R 2 216209589 216209589 CORL279_LUNG 37 Missense_Mutation SNP G A uc002vex.3 ATIC_uc010zjo.1... Hybrid_Cap... view
AURKC 19 57742494 57742507 CORL279_LUNG 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
AXIN1 16 337827 337828 CORL279_LUNG 37 3'UTR Ins - G rs61433087 uc002cgp.1 AXIN1_uc002cgq.... Hybrid_Cap...
BCL3 19 45262965 45262968 CORL279_LUNG 37 3'UTR Del CCCC - uc010xxe.1 Hybrid_Cap...
BRD2 6 32948599 32948599 CORL279_LUNG 37 3'UTR Del C - uc010juh.2 BRD2_uc003ocn.3... Hybrid_Cap...
C15ORF2 p.S222I 15 24921679 24921679 CORL279_LUNG 37 Missense_Mutation SNP G T uc001ywo.2 Hybrid_Cap... view
CARD9 p.V48V 9 139266387 139266387 CORL279_LUNG 37 Silent SNP C T uc004chg.3 CARD9_uc011mdw.... Hybrid_Cap... view
CATSPERB p.R510S 14 92105499 92105499 CORL279_LUNG 37 Missense_Mutation SNP G T uc001xzs.1 CATSPERB_uc010a... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 CORL279_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 CORL279_LUNG 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CXCR2 p.W170C 2 219000034 219000034 CORL279_LUNG 37 Missense_Mutation SNP G C uc002vgz.1 CXCR2_uc002vha.... Hybrid_Cap... view
DFNA5 7 24783982 24783982 CORL279_LUNG 37 Intron Del C - uc010kus.1 DFNA5_uc003swz.... Hybrid_Cap...
EDN1 6 12296150 12296151 CORL279_LUNG 37 Intron Ins - T rs66570617 uc003nae.3 EDN1_uc003nad.2... Hybrid_Cap...
EP300 22 41574970 41574972 CORL279_LUNG 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 CORL279_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHB1 p.E20_splice 3 134644656 134644656 CORL279_LUNG 37 Splice_Site_SNP SNP A G uc003eqt.2 EPHB1_uc010htz.... Hybrid_Cap... view
ERCC3 p.R742W 2 128015297 128015297 CORL279_LUNG 37 Missense_Mutation SNP G A uc002toh.1 ERCC3_uc002toe.... Hybrid_Cap... view
ERCC3 2 128047671 128047675 CORL279_LUNG 37 Intron Del TTCTC - uc002toh.1 ERCC3_uc002toe.... Hybrid_Cap...
EXT1 8 118811807 118811807 CORL279_LUNG 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
FANCI 15 89826363 89826363 CORL279_LUNG 37 Intron SNP C T uc010bnp.1 FANCI_uc002bnm.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 CORL279_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 CORL279_LUNG 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 CORL279_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNA X 153577132 153577133 CORL279_LUNG 37 3'UTR Ins - CA rs10692455;rs71733538 uc004fkk.2 FLNA_uc004fki.2... Hybrid_Cap...
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 CORL279_LUNG 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FN1 2 216244182 216244185 CORL279_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FZD1 p.93_94insP 7 90894459 90894460 CORL279_LUNG 37 In_Frame_Ins Ins - CCG uc003ula.2 Hybrid_Cap...
GRIA3 X 122318386 122318387 CORL279_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 CORL279_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HAPLN1 p.R247K 5 82940217 82940217 CORL279_LUNG 37 Missense_Mutation SNP C T uc003kim.2 HAPLN1_uc003kin... Hybrid_Cap... view
HDAC2 p.P49L 6 114292209 114292209 CORL279_LUNG 37 Missense_Mutation SNP G A uc003pwd.1 HDAC2_uc003pwc.... Hybrid_Cap... view
HNF1A 12 121434630 121434631 CORL279_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 CORL279_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INPP5D 2 234115396 234115396 CORL279_LUNG 37 3'UTR SNP C T uc010zmo.1 INPP5D_uc010zmp... Hybrid_Cap... view
ITIH5L p.H111N X 54818396 54818397 CORL279_LUNG 37 Missense_Mutation DNP GG TT uc004dtj.2 Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 CORL279_LUNG 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KALRN p.T2227K 3 124386010 124386010 CORL279_LUNG 37 Missense_Mutation SNP C A uc003ehg.2 KALRN_uc003ehi.... Hybrid_Cap... view
KLK7 19 51480672 51480675 CORL279_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LPP p.R418C 3 188477912 188477912 CORL279_LUNG 37 Missense_Mutation SNP C T rs116281242 uc003frs.1 LPP_uc011bsg.1_... Hybrid_Cap... view
LRP1B p.G4011E 2 141093268 141093268 CORL279_LUNG 37 Missense_Mutation SNP C T uc002tvj.1 Hybrid_Cap... view
LRP1B p.R2563L 2 141291664 141291664 CORL279_LUNG 37 Missense_Mutation SNP C A uc002tvj.1 Hybrid_Cap... view
LRP2 p.P4620L 2 169985282 169985282 CORL279_LUNG 37 Missense_Mutation SNP G A uc002ues.2 Hybrid_Cap... view
LRRC7 p.Y690* 1 70502203 70502203 CORL279_LUNG 37 Nonsense_Mutation SNP C G uc001dep.2 LRRC7_uc009wbg.... Hybrid_Cap... view
LRRC7 p.H1176Q 1 70505149 70505149 CORL279_LUNG 37 Missense_Mutation SNP C A uc001dep.2 LRRC7_uc009wbg.... Hybrid_Cap... view
MAF 16 79632478 79632479 CORL279_LUNG 37 Intron Ins - GT rs67364240 uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 CORL279_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 CORL279_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 CORL279_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K8 p.L33R 10 30727965 30727965 CORL279_LUNG 37 Missense_Mutation SNP T G uc001ivi.1 MAP3K8_uc009xlf... Hybrid_Cap... view
MCM3AP 21 47666864 47666864 CORL279_LUNG 37 Intron SNP G A uc002zir.1 MCM3APAS_uc002z... Hybrid_Cap... view
MCM3APAS 21 47671275 47671276 CORL279_LUNG 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MGA p.R1053* 15 42005421 42005421 CORL279_LUNG 37 Nonsense_Mutation SNP C T uc010ucy.1 MGA_uc001zog.1_... Hybrid_Cap... view
MSH3 p.PPA66del 5 79950742 79950750 CORL279_LUNG 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MYH11 16 15843931 15843931 CORL279_LUNG 37 Intron SNP C T uc002ddx.2 MYH11_uc002ddv.... Hybrid_Cap... view
MYLK4 p.W58* 6 2693080 2693080 CORL279_LUNG 37 Nonsense_Mutation SNP C T uc003mty.3 Hybrid_Cap... view
MYO18B 22 26156975 26156975 CORL279_LUNG 37 De_novo_Start_OutOfFrame SNP G A uc003abz.1 MYO18B_uc003aca... Hybrid_Cap... view
MYO18B p.Q89H 22 26164150 26164150 CORL279_LUNG 37 Missense_Mutation SNP G T uc003abz.1 MYO18B_uc003aca... Hybrid_Cap... view
NCAM1 11 112832307 112832308 CORL279_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 CORL279_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NF2 22 30079072 30079073 CORL279_LUNG 37 Intron Del CT - uc003age.3 NF2_uc003afy.3_... Hybrid_Cap...
NPR1 1 153665919 153665920 CORL279_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 CORL279_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 CORL279_LUNG 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NRAS p.K5R 1 115258768 115258768 CORL279_LUNG 37 Missense_Mutation SNP T C uc009wgu.2 Hybrid_Cap... view
P2RX7 p.Y343S 12 121615005 121615005 CORL279_LUNG 37 Missense_Mutation SNP A C uc001tzm.2 P2RX7_uc001tzn.... Hybrid_Cap... view
PAX3 2 223158653 223158653 CORL279_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PCM1 8 17885407 17885408 CORL279_LUNG 37 3'UTR Ins - T rs117750062 uc003wyi.3 PCM1_uc011kyh.1... Hybrid_Cap...
PDE4DIP p.K1948E 1 144864253 144864253 CORL279_LUNG 37 Missense_Mutation SNP T C uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PDE4DIP p.Q1665fs 1 144873963 144873963 CORL279_LUNG 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.V486fs 1 144917828 144917828 CORL279_LUNG 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDGFRA 4 55131002 55131002 CORL279_LUNG 37 Intron Del A - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PGR 11 100933598 100933599 CORL279_LUNG 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PLK2 5 57755014 57755014 CORL279_LUNG 37 Intron Del A - uc003jrn.2 PLK2_uc011cql.1... Hybrid_Cap...
PRKCA 17 64298959 64298960 CORL279_LUNG 37 5'UTR Ins - G rs71160558 uc002jfp.1 PRKCA_uc002jfo.... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 CORL279_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTPRC 1 198608177 198608177 CORL279_LUNG 37 5'UTR SNP T C uc001gur.1 PTPRC_uc001gus.... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 CORL279_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RUNX1T1 8 93023169 93023169 CORL279_LUNG 37 Intron SNP A T uc011lgi.1 RUNX1T1_uc003yf... Hybrid_Cap... view
SCYL1 p.W649* 11 65304586 65304586 CORL279_LUNG 37 Nonsense_Mutation SNP G A uc001oea.1 SCYL1_uc009yqk.... Hybrid_Cap... view
SEMA5B p.N751K 3 122632408 122632408 CORL279_LUNG 37 Missense_Mutation SNP G C uc003efz.1 SEMA5B_uc011bju... Hybrid_Cap... view
SFPQ 1 35650023 35650026 CORL279_LUNG 37 3'UTR Del AAAA - uc001bys.2 SFPQ_uc001byr.2... Hybrid_Cap...
SMO p.G497V 7 128850227 128850227 CORL279_LUNG 37 Missense_Mutation SNP G T uc003vor.2 SMO_uc003vos.2_... Hybrid_Cap... view
STK31 7 23872024 23872025 CORL279_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TEC 4 48139307 48139310 CORL279_LUNG 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TGFB2 1 218519928 218519929 CORL279_LUNG 37 5'UTR Ins - AAAC uc001hln.2 TGFB2_uc001hll.... Hybrid_Cap...
TIE1 p.T114M 1 43770804 43770804 CORL279_LUNG 37 Missense_Mutation SNP C T uc001ciu.2 TIE1_uc010okd.1... Hybrid_Cap... view
TIE1 p.E172K 1 43772540 43772540 CORL279_LUNG 37 Missense_Mutation SNP G A uc001ciu.2 TIE1_uc010okd.1... Hybrid_Cap... view
TP53 p.Y126_splice 17 7578546 7578558 CORL279_LUNG 37 Splice_Site_Del Del AGGGG... - uc002gim.2 TP53_uc002gig.1... Hybrid_Cap...
TP63 3 189507518 189507519 CORL279_LUNG 37 Intron Ins - AG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIM24 7 138269818 138269818 CORL279_LUNG 37 3'UTR SNP C T uc003vuc.2 TRIM24_uc003vub... Hybrid_Cap... view
TRIO p.R1006C 5 14368958 14368958 CORL279_LUNG 37 Missense_Mutation SNP C T uc003jff.2 TRIO_uc003jfg.2... Hybrid_Cap... view
TRPS1 8 116635872 116635873 CORL279_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTBK1 p.E771del 6 43250726 43250728 CORL279_LUNG 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
TTN 2 179612659 179612659 CORL279_LUNG 37 Intron SNP T A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
UBR5 p.S2325N 8 103283473 103283473 CORL279_LUNG 37 Missense_Mutation SNP C T uc003ykr.1 UBR5_uc003yks.1... Hybrid_Cap... view
VEGFA 6 43746423 43746423 CORL279_LUNG 37 Intron SNP A G rs3025048 uc003owh.2 VEGFA_uc003owc.... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 CORL279_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...