Annotation Summary for Cell Line: COR-L88  

Cell line primary name: COR-L88
Cell line aliases:
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: small_cell_carcinoma
Notes:
Source: ECACC
Expression arrays: CRAZY_p_NCLE_RNA10_HG-U133_Plus_2_E11_569432
SNP arrays: MISTS_p_NCLE_DNAAffy11_GenomeWideSNP_6_E03_578338
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in COR-L88

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM17 2 9630245 9630245 CORL88_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 CORL88_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 CORL88_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK1 4 113347609 113347610 CORL88_LUNG 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.1388_1389FF>F 18 56203253 56203255 CORL88_LUNG 37 In_Frame_Del Del AAG - uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ANAPC5 12 121755897 121755897 CORL88_LUNG 37 Intron SNP A T uc001uag.2 ANAPC5_uc010szu... Hybrid_Cap... view
ATR p.R1351L 3 142242935 142242935 CORL88_LUNG 37 Missense_Mutation SNP C A uc003eux.3 Hybrid_Cap... view
BAI3 p.T961S 6 70034830 70034830 CORL88_LUNG 37 Missense_Mutation SNP A T uc003pev.3 BAI3_uc010kak.2... Hybrid_Cap... view
BAI3 p.M1096_splice 6 70048907 70048907 CORL88_LUNG 37 Splice_Site_SNP SNP G C uc003pev.3 BAI3_uc010kak.2... Hybrid_Cap... view
BAI3 p.T1280S 6 70071004 70071004 CORL88_LUNG 37 Missense_Mutation SNP C G uc003pev.3 BAI3_uc010kak.2... Hybrid_Cap... view
BIRC5 17 76219784 76219785 CORL88_LUNG 37 3'UTR Ins - AA uc002jvf.2 BIRC5_uc002jvg.... Hybrid_Cap...
BRCA2 p.E443* 13 32906942 32906942 CORL88_LUNG 37 Nonsense_Mutation SNP G T uc001uub.1 BRCA2_uc001uua.... Hybrid_Cap... view
CABC1 1 227171585 227171585 CORL88_LUNG 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CARD9 p.H236H 9 139265073 139265073 CORL88_LUNG 37 Silent SNP G A uc004chg.3 CARD9_uc011mdw.... Hybrid_Cap... view
CDK6 p.T88S 7 92404117 92404117 CORL88_LUNG 37 Missense_Mutation SNP T A uc011khw.1 CDK6_uc010lez.2... Hybrid_Cap... view
CEP110 p.A861T 9 123903756 123903756 CORL88_LUNG 37 Missense_Mutation SNP G A uc004bkx.1 CEP110_uc004bky... Hybrid_Cap... view
CFI 4 110723140 110723140 CORL88_LUNG 37 5'UTR SNP C G rs113612355 uc011cft.1 CFI_uc003hzr.3_... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 CORL88_LUNG 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 CORL88_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 CORL88_LUNG 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CSMD3 8 113236962 113236962 CORL88_LUNG 37 3'UTR SNP C T uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CSMD3 p.S2471T 8 113326795 113326795 CORL88_LUNG 37 Missense_Mutation SNP C G uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CTLA4 p.L98fs 2 204735492 204735492 CORL88_LUNG 37 Frame_Shift_Del Del T - uc002vak.1 CTLA4_uc002val.... Hybrid_Cap...
CTSL1 p.E26Q 9 90342594 90342594 CORL88_LUNG 37 Missense_Mutation SNP G C uc004aph.2 CTSL1_uc004api.... Hybrid_Cap... view
CYP19A1 p.K99_splice 15 51520131 51520131 CORL88_LUNG 37 Splice_Site_SNP SNP C A uc001zyz.3 CYP19A1_uc001zz... Hybrid_Cap... view
DHFR p.W25* 5 79950681 79950681 CORL88_LUNG 37 Nonsense_Mutation SNP C T uc003kgx.1 MSH3_uc003kgz.2... Hybrid_Cap... view
DNAH8 p.T753A 6 38770961 38770961 CORL88_LUNG 37 Missense_Mutation SNP A G uc003ooe.1 Hybrid_Cap... view
DSTYK p.Q160E 1 205156722 205156722 CORL88_LUNG 37 Missense_Mutation SNP G C uc001hbw.2 DSTYK_uc001hbx.... Hybrid_Cap... view
EGFR 7 55270463 55270463 CORL88_LUNG 37 Intron SNP C T uc003tqk.2 EGFR_uc010kzg.1... Hybrid_Cap... view
EPHA5 4 66189753 66189754 CORL88_LUNG 37 3'UTR Ins - T rs67487372 uc011cah.1 EPHA5_uc003hcx.... Hybrid_Cap...
EPHA6 3 97367230 97367231 CORL88_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHB6 7 142568771 142568771 CORL88_LUNG 37 3'UTR Del C - uc011kst.1 EPHB6_uc011ksu.... Hybrid_Cap...
ETV1 7 14028708 14028708 CORL88_LUNG 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 CORL88_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 CORL88_LUNG 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 CORL88_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNB p.D624G 3 58092530 58092530 CORL88_LUNG 37 Missense_Mutation SNP A G uc010hne.2 FLNB_uc003djj.2... Hybrid_Cap... view
FSCB p.E116A 14 44975844 44975844 CORL88_LUNG 37 Missense_Mutation SNP T G uc001wvn.2 Hybrid_Cap... view
GRIA3 X 122318386 122318387 CORL88_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 CORL88_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HNF1A 12 121434630 121434631 CORL88_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 CORL88_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
KLK7 19 51480672 51480675 CORL88_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KSR1 17 25904747 25904747 CORL88_LUNG 37 Intron SNP G A uc010crg.2 KSR1_uc002gzj.1... Hybrid_Cap... view
LRP1 p.Q255E 12 57539195 57539195 CORL88_LUNG 37 Missense_Mutation SNP C G uc001snd.2 LRP1_uc010sre.1... Hybrid_Cap... view
LRP1B p.R2234* 2 141457918 141457918 CORL88_LUNG 37 Nonsense_Mutation SNP T A uc002tvj.1 Hybrid_Cap... view
LRP1B p.C870Y 2 141751599 141751599 CORL88_LUNG 37 Missense_Mutation SNP C T uc002tvj.1 LRP1B_uc010fnl.... Hybrid_Cap... view
LRP2 p.D2771N 2 170058279 170058279 CORL88_LUNG 37 Missense_Mutation SNP C T uc002ues.2 Hybrid_Cap... view
LRRK2 p.Q536K 12 40657653 40657653 CORL88_LUNG 37 Missense_Mutation SNP C A uc001rmg.3 LRRK2_uc001rmh.... Hybrid_Cap... view
LTK p.E174D 15 41804150 41804150 CORL88_LUNG 37 Missense_Mutation SNP C A uc001zoa.3 LTK_uc001zob.3_... Hybrid_Cap... view
MAF 16 79628325 79628325 CORL88_LUNG 37 3'UTR Del A - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 CORL88_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 CORL88_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 CORL88_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPKAPK3 3 50685575 50685575 CORL88_LUNG 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MCM4 p.G392D 8 48882358 48882358 CORL88_LUNG 37 Missense_Mutation SNP G A uc003xqk.1 MCM4_uc003xql.1... Hybrid_Cap... view
MFSD2A 1 40435515 40435515 CORL88_LUNG 37 3'UTR Del T - rs79314830 uc001cev.2 MFSD2A_uc001ceu... Hybrid_Cap...
MLL3 p.Y816fs 7 151945071 151945072 CORL88_LUNG 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
MLLT4 p.M1529I 6 168352645 168352645 CORL88_LUNG 37 Missense_Mutation SNP G T uc003qwd.2 MLLT4_uc003qwb.... Hybrid_Cap... view
MMP2 p.A571T 16 55532302 55532302 CORL88_LUNG 37 Missense_Mutation SNP G A uc002ehz.3 MMP2_uc010vhd.1... Hybrid_Cap... view
MN1 p.533_533Q>QQ 22 28194933 28194934 CORL88_LUNG 37 In_Frame_Ins Ins - TGC rs45480998 uc003adj.2 Hybrid_Cap...
MSH3 p.PPA66del 5 79950742 79950750 CORL88_LUNG 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MYO18B p.M2111_splice 22 26399277 26399277 CORL88_LUNG 37 Splice_Site_SNP SNP T A uc003abz.1 MYO18B_uc003aca... Hybrid_Cap... view
MYO3B p.H316L 2 171225863 171225863 CORL88_LUNG 37 Missense_Mutation SNP A T rs55633190 uc002ufy.2 MYO3B_uc002ufv.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 CORL88_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 CORL88_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.QQQ1272del 20 46279815 46279823 CORL88_LUNG 37 In_Frame_Del Del GCAGC... - uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NIPBL p.R894H 5 36985963 36985963 CORL88_LUNG 37 Missense_Mutation SNP G A uc003jkl.3 NIPBL_uc003jkk.... Hybrid_Cap... view
NLRP1 17 5405010 5405010 CORL88_LUNG 37 3'UTR SNP A C uc002gcg.1 LOC728392_uc010... Hybrid_Cap... view
NPR1 1 153665919 153665920 CORL88_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 CORL88_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP214 9 134067556 134067557 CORL88_LUNG 37 Intron Ins - T rs66652901 uc004cag.2 NUP214_uc004cah... Hybrid_Cap...
OBSCN p.R1221Q 1 228433294 228433294 CORL88_LUNG 37 Missense_Mutation SNP G A uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
ODZ1 p.T2329N X 123517795 123517795 CORL88_LUNG 37 Missense_Mutation SNP G T uc010nqy.2 ODZ1_uc011muj.1... Hybrid_Cap... view
PAX5 9 37034095 37034095 CORL88_LUNG 37 5'UTR Del C - uc003zzo.1 PAX5_uc011lpw.1... Hybrid_Cap...
PDE4DIP p.E243fs 1 144923729 144923729 CORL88_LUNG 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDGFRA 4 55131002 55131002 CORL88_LUNG 37 Intron Del A - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 CORL88_LUNG 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PLCG2 p.K80E 16 81888093 81888093 CORL88_LUNG 37 Missense_Mutation SNP A G uc002fgt.2 PLCG2_uc010chg.... Hybrid_Cap... view
PORCN X 48378986 48378987 CORL88_LUNG 37 3'UTR Del AC - uc010nie.1 PORCN_uc004djr.... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 CORL88_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG1 10 52751088 52751089 CORL88_LUNG 37 5'UTR Ins - GCT rs67900156;rs71029335 uc001jjm.2 PRKG1_uc010qhp.... Hybrid_Cap...
PTPRD p.G446V 9 8518054 8518054 CORL88_LUNG 37 Missense_Mutation SNP C A uc003zkk.2 PTPRD_uc003zkp.... Hybrid_Cap... view
RAPGEF2 4 160189224 160189224 CORL88_LUNG 37 5'UTR SNP A T uc003iqg.3 Hybrid_Cap... view
RB1 p.N406_splice 13 48951053 48951053 CORL88_LUNG 37 Splice_Site_SNP SNP G A uc001vcb.2 RB1_uc010act.1_... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 CORL88_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RPS6KL1 14 75373626 75373627 CORL88_LUNG 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SACS p.F270L 13 23929941 23929941 CORL88_LUNG 37 Missense_Mutation SNP A C rs116907814 uc001uon.2 SACS_uc001uoo.2... Hybrid_Cap... view
SGK269 p.P282T 15 77473425 77473425 CORL88_LUNG 37 Missense_Mutation SNP G T uc002bcm.2 SGK269_uc002bcn... Hybrid_Cap... view
SOX2 p.S239Y 3 181430864 181430864 CORL88_LUNG 37 Missense_Mutation SNP C A uc003fkx.2 SOX2OT_uc003fkv... Hybrid_Cap... view
SRPK1 p.G242I 6 35840366 35840367 CORL88_LUNG 37 Missense_Mutation DNP CC AT uc003olj.2 SRPK1_uc011dtg.... Hybrid_Cap...
STK25 2 242435659 242435662 CORL88_LUNG 37 Intron Del AAGG - rs3215138;rs75497042 uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap...
SULF1 p.E651G 8 70540011 70540011 CORL88_LUNG 37 Missense_Mutation SNP A G uc010lza.1 SULF1_uc003xyd.... Hybrid_Cap... view
TBX22 p.P482T X 79286491 79286491 CORL88_LUNG 37 Missense_Mutation SNP C A uc010nmg.1 TBX22_uc004edi.... Hybrid_Cap... view
TCF21 6 134210497 134210498 CORL88_LUNG 37 5'UTR Ins - TCTC rs35199378 uc003qei.3 TCF21_uc003qej.... Hybrid_Cap...
TEK p.V146L 9 27168564 27168564 CORL88_LUNG 37 Missense_Mutation SNP G C uc003zqi.3 TEK_uc010mjc.1_... Hybrid_Cap... view
TIE1 p.G392D 1 43774789 43774789 CORL88_LUNG 37 Missense_Mutation SNP G A uc001ciu.2 TIE1_uc010okd.1... Hybrid_Cap... view
TIE1 1 43779118 43779118 CORL88_LUNG 37 Intron SNP G C uc001ciu.2 TIE1_uc010okd.1... Hybrid_Cap... view
TLE1 p.G170C 9 84249111 84249111 CORL88_LUNG 37 Missense_Mutation SNP C A uc004alz.2 TLE1_uc004aly.2... Hybrid_Cap... view
TMPO p.M457T 12 98927405 98927405 CORL88_LUNG 37 Missense_Mutation SNP T C uc001tfh.1 TMPO_uc001tfi.1... Hybrid_Cap... view
TNN p.Y296fs 1 175049402 175049402 CORL88_LUNG 37 Frame_Shift_Del Del C - uc001gkl.1 TNN_uc010pmx.1_... Hybrid_Cap...
TP53 p.V157F 17 7578461 7578461 CORL88_LUNG 37 Missense_Mutation SNP C A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIP11 p.E1639* 14 92461837 92461837 CORL88_LUNG 37 Nonsense_Mutation SNP C A uc001xzy.2 TRIP11_uc010auf... Hybrid_Cap... view
TRPS1 8 116635872 116635873 CORL88_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TRRAP p.A3750V 7 98609112 98609112 CORL88_LUNG 37 Missense_Mutation SNP C T uc003upp.2 TRRAP_uc011kis.... Hybrid_Cap... view
TTN 2 179391639 179391640 CORL88_LUNG 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.G6631L 2 179584745 179584746 CORL88_LUNG 37 Missense_Mutation DNP CC AA uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.T5888I 2 179588591 179588591 CORL88_LUNG 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.S528C 2 179656878 179656878 CORL88_LUNG 37 Missense_Mutation SNP G C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VAV1 p.M254fs 19 6825352 6825352 CORL88_LUNG 37 Frame_Shift_Del Del G - uc002mfu.1 VAV1_uc010xjh.1... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 CORL88_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
ZFYVE9 p.A1008E 1 52747486 52747486 CORL88_LUNG 37 Missense_Mutation SNP C A uc001cto.2 ZFYVE9_uc001ctp... Hybrid_Cap... view