Annotation Summary for Cell Line: Calu-6  

Cell line primary name: Calu-6
Cell line aliases:
Gender: F
Site Primary: lung
Histology: carcinoma
Hist Subtype1: undifferentiated_carcinoma
Notes:
Source: ATCC
Expression arrays: BRAKE_p_NCLE_RNA2_HG-U133_Plus_2_E04_241144
SNP arrays: HONEY_p_NCLE_DNAAffy3_S_GenomeWideSNP_6_G10_293442
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in Calu-6

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 CALU6_LUNG 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM17 2 9630245 9630245 CALU6_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 CALU6_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS19 p.S909R 5 129019893 129019893 CALU6_LUNG 37 Missense_Mutation SNP C G uc003kvb.1 ADAMTS19_uc010j... Hybrid_Cap... view
ALDH7A1 5 125930950 125930950 CALU6_LUNG 37 5'UTR SNP C T uc003ktx.2 ALDH7A1_uc003kt... Hybrid_Cap... view
ALPK1 4 113347609 113347610 CALU6_LUNG 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
BAI3 p.D1051Y 6 70042863 70042863 CALU6_LUNG 37 Missense_Mutation SNP G T uc003pev.3 BAI3_uc010kak.2... Hybrid_Cap... view
BAP1 p.R512L 3 52437626 52437626 CALU6_LUNG 37 Missense_Mutation SNP C A uc003ddx.2 BAP1_uc003ddw.2... Hybrid_Cap... view
BMP4 14 54416602 54416602 CALU6_LUNG 37 3'UTR Del T - rs76335800 uc001xal.3 BMP4_uc010aoh.2... Hybrid_Cap...
BUB1 p.F1031Y 2 111395707 111395707 CALU6_LUNG 37 Missense_Mutation SNP A T uc002tgc.2 BUB1_uc010yxh.1... Hybrid_Cap... view
CARD10 p.KE272del 22 37906309 37906314 CALU6_LUNG 37 In_Frame_Del Del CTCCT... - uc003asx.1 CARD10_uc003ast... Hybrid_Cap...
CARD11 p.T670M 7 2962899 2962899 CALU6_LUNG 37 Missense_Mutation SNP G A rs3735134 uc003smv.2 Hybrid_Cap... view
CDC42BPA p.M275L 1 227335131 227335131 CALU6_LUNG 37 Missense_Mutation SNP T A uc001hqr.2 CDC42BPA_uc001h... Hybrid_Cap... view
CDH2 p.A118V 18 25593693 25593693 CALU6_LUNG 37 Missense_Mutation SNP G A uc002kwg.2 CDH2_uc010xbn.1... Hybrid_Cap... view
CHD8 14 21853629 21853630 CALU6_LUNG 37 3'UTR Ins - T rs75170206;rs78520772 uc001was.1 CHD8_uc001war.1... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 CALU6_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 p.S24I 3 1262386 1262386 CALU6_LUNG 37 Missense_Mutation SNP G T uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap... view
CNTN6 3 1339681 1339686 CALU6_LUNG 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CNTN6 p.G735E 3 1424663 1424663 CALU6_LUNG 37 Missense_Mutation SNP G A uc003boz.2 CNTN6_uc011asj.... Hybrid_Cap... view
CSMD3 p.T1303M 8 113585864 113585864 CALU6_LUNG 37 Missense_Mutation SNP G A uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CYLD 16 50818375 50818375 CALU6_LUNG 37 Intron SNP C A uc002egp.1 CYLD_uc002ego.2... Hybrid_Cap... view
DNMT1 p.S1266F 19 10250731 10250731 CALU6_LUNG 37 Missense_Mutation SNP G A uc010xlc.1 DNMT1_uc002mne.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 CALU6_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ETV1 7 14028708 14028708 CALU6_LUNG 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 CALU6_LUNG 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FN1 2 216244182 216244185 CALU6_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GRIA3 X 122318386 122318387 CALU6_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 CALU6_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIP1 p.R300Q 7 75192360 75192360 CALU6_LUNG 37 Missense_Mutation SNP C T uc003uds.1 HIP1_uc011kfz.1... Hybrid_Cap... view
HNF1A 12 121434630 121434631 CALU6_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 CALU6_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INHBA 7 41729121 41729122 CALU6_LUNG 37 3'UTR Ins - T uc003thq.2 INHBA_uc003thr.... Hybrid_Cap...
IRAK3 12 66642028 66642028 CALU6_LUNG 37 3'UTR SNP G T uc001sth.2 IRAK3_uc010ssy.... Hybrid_Cap... view
ITGB1 10 33197131 33197134 CALU6_LUNG 37 Intron Del CTTT - rs116966876 uc001iwq.3 ITGB1_uc001iwp.... Hybrid_Cap...
KLK7 19 51480672 51480675 CALU6_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KRAS p.Q61K 12 25380277 25380278 CALU6_LUNG 37 Missense_Mutation DNP GA TG uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 CALU6_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 CALU6_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K11 p.E53K 11 65381071 65381071 CALU6_LUNG 37 Missense_Mutation SNP C T uc001oew.2 MAP3K11_uc010ro... Hybrid_Cap... view
MAP3K9 p.T1040I 14 71197335 71197335 CALU6_LUNG 37 Missense_Mutation SNP G A uc001xml.2 MAP3K9_uc010ttk... Hybrid_Cap... view
MAP3K9 p.V579F 14 71205071 71205071 CALU6_LUNG 37 Missense_Mutation SNP C A uc001xml.2 MAP3K9_uc010ttk... Hybrid_Cap... view
MAPKBP1 15 42111753 42111754 CALU6_LUNG 37 Intron Ins - C rs3034891 uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap...
MCM3APAS 21 47671275 47671276 CALU6_LUNG 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MECOM p.Y18Y 3 169099296 169099296 CALU6_LUNG 37 Silent SNP A G uc011bpj.1 MECOM_uc003ffl.... Hybrid_Cap... view
MERTK p.M790V 2 112779853 112779853 CALU6_LUNG 37 Missense_Mutation SNP A G uc002thk.1 MERTK_uc002thl.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 CALU6_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 CALU6_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA1 p.E905K 2 24949571 24949571 CALU6_LUNG 37 Missense_Mutation SNP G A uc002rfk.2 NCOA1_uc010eye.... Hybrid_Cap... view
NCOA3 p.Q1276del 20 46279837 46279839 CALU6_LUNG 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK11 p.R180* 3 130852691 130852691 CALU6_LUNG 37 Nonsense_Mutation SNP C T uc003eny.2 NEK11_uc003enx.... Hybrid_Cap... view
NIN p.L1519F 14 51221569 51221569 CALU6_LUNG 37 Missense_Mutation SNP G A uc001wyi.2 NIN_uc001wyj.2_... Hybrid_Cap... view
NPR1 1 153665919 153665920 CALU6_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NPR2 p.C599R 9 35802584 35802584 CALU6_LUNG 37 Missense_Mutation SNP T C uc003zyd.2 NPR2_uc010mlb.2... Hybrid_Cap... view
NR1H2 p.176_177insQ 19 50881820 50881821 CALU6_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP214 9 134067556 134067557 CALU6_LUNG 37 Intron Ins - T rs66652901 uc004cag.2 NUP214_uc004cah... Hybrid_Cap...
PAX3 2 223065752 223065752 CALU6_LUNG 37 3'UTR SNP A T uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap... view
PAX3 2 223158653 223158653 CALU6_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP p.Q1665fs 1 144873963 144873963 CALU6_LUNG 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PGGT1B 5 114548071 114548072 CALU6_LUNG 37 3'UTR Ins - C uc003kqw.3 PGGT1B_uc003kqx... Hybrid_Cap...
PREX2 p.E262* 8 68950472 68950472 CALU6_LUNG 37 Nonsense_Mutation SNP G T uc003xxv.1 PREX2_uc003xxu.... Hybrid_Cap... view
PRKCE p.P33Q 2 45879337 45879337 CALU6_LUNG 37 Missense_Mutation SNP C A uc002rut.2 Hybrid_Cap... view
PRKD3 2 37480319 37480320 CALU6_LUNG 37 Stop_Codon_Ins Ins - T rs79875666 uc002rqd.2 Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 CALU6_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKDC p.A1067V 8 48815198 48815198 CALU6_LUNG 37 Missense_Mutation SNP G A uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 CALU6_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROCK1 p.R10* 18 18690844 18690844 CALU6_LUNG 37 Nonsense_Mutation SNP G A uc002kte.2 Hybrid_Cap... view
RPS6KA5 14 91360733 91360734 CALU6_LUNG 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
RPS6KL1 14 75373626 75373627 CALU6_LUNG 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
STK31 7 23872024 23872025 CALU6_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TGFB2 1 218519928 218519929 CALU6_LUNG 37 5'UTR Ins - AAAC uc001hln.2 TGFB2_uc001hll.... Hybrid_Cap...
TLK1 2 171850178 171850179 CALU6_LUNG 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TNRC6B p.Q1328del 22 40697177 40697179 CALU6_LUNG 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TP53 p.R196* 17 7578263 7578263 CALU6_LUNG 37 Nonsense_Mutation SNP G A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 CALU6_LUNG 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIM33 1 114940215 114940216 CALU6_LUNG 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRPS1 8 116635872 116635873 CALU6_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TSC2 16 2138671 2138672 CALU6_LUNG 37 3'UTR Del AA - uc002con.2 TSC2_uc010bsd.2... Hybrid_Cap...
TTN p.V15617M 2 179468861 179468861 CALU6_LUNG 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.R1003H 2 179647625 179647625 CALU6_LUNG 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
USP6 p.D753H 17 5049407 5049407 CALU6_LUNG 37 Missense_Mutation SNP G C uc002gau.1 USP6_uc002gav.1... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 CALU6_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
ZAK 2 174131511 174131512 CALU6_LUNG 37 3'UTR Ins - AAA rs75896701 uc002uhz.2 Hybrid_Cap...
ZFYVE9 p.A140S 1 52703507 52703507 CALU6_LUNG 37 Missense_Mutation SNP G T uc001cto.2 ZFYVE9_uc001ctn... Hybrid_Cap... view