Annotation Summary for Cell Line: DK-MG  

Cell line primary name: DK-MG
Cell line aliases:
Gender: F
Site Primary: central_nervous_system
Histology: glioma
Hist Subtype1: astrocytoma_Grade_IV
Notes:
Source: DSMZ
Expression arrays: CRAZY_p_NCLE_RNA10_HG-U133_Plus_2_H11_569412
SNP arrays: FASTS_p_NCLE_DNAAffy4_S_GenomeWideSNP_6_B11_335232
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in DK-MG

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 DKMG_CENTRAL_NE... 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACACA p.F1992L 17 35482686 35482686 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP A G uc002hno.2 ACACA_uc002hnk.... Hybrid_Cap... view
ACACA 17 35766564 35766564 DKMG_CENTRAL_NE... 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM17 2 9630245 9630245 DKMG_CENTRAL_NE... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 DKMG_CENTRAL_NE... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 DKMG_CENTRAL_NE... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK2 p.1388_1389FF>F 18 56203253 56203255 DKMG_CENTRAL_NE... 37 In_Frame_Del Del AAG - uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
AURKC 19 57742494 57742507 DKMG_CENTRAL_NE... 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BCR 22 23631813 23631814 DKMG_CENTRAL_NE... 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BCR 22 23632777 23632778 DKMG_CENTRAL_NE... 37 Intron Ins - T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BLM p.Q548* 15 91304245 91304245 DKMG_CENTRAL_NE... 37 Nonsense_Mutation SNP C T uc002bpr.2 BLM_uc010uqh.1_... Hybrid_Cap... view
BMP4 14 54416601 54416602 DKMG_CENTRAL_NE... 37 3'UTR Ins - AT rs74495140;rs76335800 uc001xal.3 BMP4_uc010aoh.2... Hybrid_Cap...
BRD2 6 32948599 32948599 DKMG_CENTRAL_NE... 37 3'UTR Del C - uc010juh.2 BRD2_uc003ocn.3... Hybrid_Cap...
BUB1 p.D294E 2 111423915 111423915 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP A T uc002tgc.2 BUB1_uc010yxh.1... Hybrid_Cap... view
C17ORF37 17 37885640 37885641 DKMG_CENTRAL_NE... 37 3'UTR Ins - G rs75811535 uc002hsq.2 Hybrid_Cap...
CABC1 1 227171585 227171585 DKMG_CENTRAL_NE... 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CABC1 1 227171736 227171737 DKMG_CENTRAL_NE... 37 Intron Ins - T rs1574184 uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CASC5 15 40954453 40954453 DKMG_CENTRAL_NE... 37 3'UTR SNP G A uc010bbs.1 CASC5_uc010bbt.... Hybrid_Cap... view
CDKL3 p.R497* 5 133640228 133640228 DKMG_CENTRAL_NE... 37 Nonsense_Mutation SNP G A uc003kzf.3 CDKL3_uc011cxm.... Hybrid_Cap... view
CEP110 p.Q1233Q 9 123912497 123912497 DKMG_CENTRAL_NE... 37 Silent SNP A G uc004bkx.1 CEP110_uc004bky... Hybrid_Cap... view
CHD8 14 21853630 21853630 DKMG_CENTRAL_NE... 37 3'UTR Del T - rs78520772 uc001was.1 CHD8_uc001war.1... Hybrid_Cap...
CHL1 p.E660D 3 424158 424158 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP G T uc003bot.2 CHL1_uc003bou.2... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 DKMG_CENTRAL_NE... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CTBP2 p.K974fs 10 126678123 126678123 DKMG_CENTRAL_NE... 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
CXCL12 10 44873992 44873993 DKMG_CENTRAL_NE... 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
EP300 22 41574970 41574972 DKMG_CENTRAL_NE... 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA10 p.F935del 1 38184441 38184443 DKMG_CENTRAL_NE... 37 In_Frame_Del Del AAG - uc009vvi.2 EPHA10_uc001cbt... Hybrid_Cap...
EPHA5 4 66189753 66189754 DKMG_CENTRAL_NE... 37 3'UTR Ins - T rs67487372 uc011cah.1 EPHA5_uc003hcx.... Hybrid_Cap...
EPHA6 3 97367230 97367231 DKMG_CENTRAL_NE... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHA8 1 22928305 22928305 DKMG_CENTRAL_NE... 37 3'UTR SNP G T uc001bfx.1 Hybrid_Cap... view
ETV1 7 14028708 14028708 DKMG_CENTRAL_NE... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 DKMG_CENTRAL_NE... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 DKMG_CENTRAL_NE... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FGFR4 p.P463S 5 176520542 176520542 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP C T uc003mfl.2 FGFR4_uc003mfm.... Hybrid_Cap... view
FLI1 11 128638217 128638217 DKMG_CENTRAL_NE... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNA X 153577132 153577133 DKMG_CENTRAL_NE... 37 3'UTR Ins - CA rs10692455;rs71733538 uc004fkk.2 FLNA_uc004fki.2... Hybrid_Cap...
FN1 p.Q603R 2 216283976 216283976 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP T C uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap... view
GLI3 p.M1312R 7 42004736 42004736 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP A C uc011kbh.1 GLI3_uc011kbg.1... Hybrid_Cap... view
GRIA3 X 122318386 122318387 DKMG_CENTRAL_NE... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 DKMG_CENTRAL_NE... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HDAC2 p.81_82insS 6 114292109 114292110 DKMG_CENTRAL_NE... 37 In_Frame_Ins Ins - CTG uc003pwd.1 HDAC2_uc003pwc.... Hybrid_Cap...
HIF1A 14 62213929 62213930 DKMG_CENTRAL_NE... 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 DKMG_CENTRAL_NE... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
IL18BP 11 71714623 71714623 DKMG_CENTRAL_NE... 37 3'UTR SNP C A uc001orh.1 IL18BP_uc009ysu... Hybrid_Cap... view
IL1B p.A65T 2 113591059 113591059 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP C T uc002tii.1 IL1B_uc002tih.1... Hybrid_Cap... view
IL1RN 2 113885167 113885167 DKMG_CENTRAL_NE... 37 Intron SNP G A rs56046326 uc002tiz.2 IL1RN_uc002tix.... Hybrid_Cap... view
ILK 11 6630029 6630029 DKMG_CENTRAL_NE... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 DKMG_CENTRAL_NE... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
JARID2 p.P1214R 6 15520382 15520382 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP C G uc003nbj.2 JARID2_uc011div... Hybrid_Cap... view
MAF 16 79628537 79628537 DKMG_CENTRAL_NE... 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAF 16 79628325 79628325 DKMG_CENTRAL_NE... 37 3'UTR Del A - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 DKMG_CENTRAL_NE... 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 DKMG_CENTRAL_NE... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 DKMG_CENTRAL_NE... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 DKMG_CENTRAL_NE... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MARK3 p.A739G 14 103969518 103969518 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP C G uc001ymz.3 MARK3_uc001ymx.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 DKMG_CENTRAL_NE... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 DKMG_CENTRAL_NE... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 p.E199K 11 113142597 113142597 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP G A uc001pns.2 NCAM1_uc001pnt.... Hybrid_Cap... view
NCOA3 p.Q1276del 20 46279837 46279839 DKMG_CENTRAL_NE... 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK1 p.S1036* 4 170345819 170345819 DKMG_CENTRAL_NE... 37 Nonsense_Mutation SNP G C uc003isd.1 NEK1_uc003isb.1... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 DKMG_CENTRAL_NE... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NPAT p.R122G 11 108060025 108060025 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP G C uc001pjz.3 NPAT_uc001pka.2... Hybrid_Cap... view
NR1H2 p.176_177insQ 19 50881820 50881821 DKMG_CENTRAL_NE... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 DKMG_CENTRAL_NE... 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUDT11 p.E118fs X 51238942 51238943 DKMG_CENTRAL_NE... 37 Frame_Shift_Ins Ins - CT uc010njt.2 Hybrid_Cap...
NUMA1 11 71728718 71728718 DKMG_CENTRAL_NE... 37 Intron SNP C T uc001orl.1 NUMA1_uc009ysw.... Hybrid_Cap... view
PAX3 2 223066017 223066018 DKMG_CENTRAL_NE... 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 DKMG_CENTRAL_NE... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDK4 7 95221928 95221928 DKMG_CENTRAL_NE... 37 Intron Del A - uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 DKMG_CENTRAL_NE... 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3CA p.N345S 3 178921552 178921552 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP A G uc003fjk.2 Hybrid_Cap... view
PKHD1 p.S3951fs 6 51484251 51484251 DKMG_CENTRAL_NE... 37 Frame_Shift_Del Del G - uc003pah.1 Hybrid_Cap...
PRKCA 17 64298959 64298960 DKMG_CENTRAL_NE... 37 5'UTR Ins - G rs71160558 uc002jfp.1 PRKCA_uc002jfo.... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 DKMG_CENTRAL_NE... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG2 4 82010742 82010742 DKMG_CENTRAL_NE... 37 3'UTR SNP T A uc003hmh.2 PRKG2_uc011ccf.... Hybrid_Cap... view
PTEN p.T167A 10 89711881 89711881 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP A G uc001kfb.2 Hybrid_Cap... view
RBPJ p.R238* 4 26426291 26426291 DKMG_CENTRAL_NE... 37 Nonsense_Mutation SNP C T rs5007634 uc003grx.1 RBPJ_uc003gry.1... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 DKMG_CENTRAL_NE... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
SLC6A8 X 152957656 152957657 DKMG_CENTRAL_NE... 37 Intron Ins - A uc004fib.3 SLC6A8_uc004fic... Hybrid_Cap...
STAT6 p.V190I 12 57500533 57500533 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP C T uc009zpg.2 STAT6_uc009zpe.... Hybrid_Cap... view
STK25 2 242435659 242435662 DKMG_CENTRAL_NE... 37 Intron Del AAGG - rs3215138;rs75497042 uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap...
TAOK3 12 118588761 118588762 DKMG_CENTRAL_NE... 37 3'UTR Ins - T rs116872184 uc001twx.2 TAOK3_uc001twv.... Hybrid_Cap...
TLK1 2 171850178 171850179 DKMG_CENTRAL_NE... 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TTN p.T8924M 2 179566903 179566903 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
ULK2 p.G498S 17 19702838 19702838 DKMG_CENTRAL_NE... 37 Missense_Mutation SNP C T uc002gwm.3 ULK2_uc002gwn.2... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 DKMG_CENTRAL_NE... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...