Annotation Summary for Cell Line: DOHH-2  

Cell line primary name: DOHH-2
Cell line aliases:
Gender: M
Site Primary: haematopoietic_and_lymphoid_tissue
Histology: lymphoid_neoplasm
Hist Subtype1: diffuse_large_B_cell_lymphoma
Notes:
Source: DSMZ
Expression arrays: SILOS_p_NCLE_RNA9_HG-U133_Plus_2_F09_523480
SNP arrays: MISTS_p_NCLE_DNAAffy11_GenomeWideSNP_6_A12_578328
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in DOHH-2

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 DOHH2_HAEMATOPO... 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM17 2 9630245 9630245 DOHH2_HAEMATOPO... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 DOHH2_HAEMATOPO... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 DOHH2_HAEMATOPO... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP6 p.K1909N 14 33292746 33292746 DOHH2_HAEMATOPO... 37 Missense_Mutation SNP A C uc001wrq.2 Hybrid_Cap... view
ALDH7A1 5 125930950 125930950 DOHH2_HAEMATOPO... 37 5'UTR SNP C T uc003ktx.2 ALDH7A1_uc003kt... Hybrid_Cap... view
ALPK1 4 113347609 113347610 DOHH2_HAEMATOPO... 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
AXL p.E757K 19 41763470 41763470 DOHH2_HAEMATOPO... 37 Missense_Mutation SNP G A uc010ehj.2 CYP2F1_uc010xvw... Hybrid_Cap... view
BCL2 18 60985222 60985222 DOHH2_HAEMATOPO... 37 Intron SNP G C uc002lit.1 BCL2_uc002liu.1... Hybrid_Cap... view
BCL3 19 45262965 45262965 DOHH2_HAEMATOPO... 37 3'UTR Del C - uc010xxe.1 Hybrid_Cap...
BCL7A 12 122497138 122497138 DOHH2_HAEMATOPO... 37 3'UTR SNP T C uc001ubo.2 BCL7A_uc001ubp.... Hybrid_Cap... view
BIRC6 p.V4691_splice 2 32832520 32832520 DOHH2_HAEMATOPO... 37 Splice_Site_SNP SNP A T uc010ezu.2 Hybrid_Cap... view
BMP4 14 54416602 54416602 DOHH2_HAEMATOPO... 37 3'UTR Del T - rs76335800 uc001xal.3 BMP4_uc010aoh.2... Hybrid_Cap...
BMPR1B p.I419T 4 96073797 96073797 DOHH2_HAEMATOPO... 37 Missense_Mutation SNP T C uc003htm.3 BMPR1B_uc010ilb... Hybrid_Cap... view
BRCA2 p.V3079L 13 32954261 32954261 DOHH2_HAEMATOPO... 37 Missense_Mutation SNP G C rs55933907 uc001uub.1 Hybrid_Cap... view
CCND3 p.I290T 6 41903688 41903688 DOHH2_HAEMATOPO... 37 Missense_Mutation SNP A G uc003orn.2 CCND3_uc003orp.... Hybrid_Cap... view
CDK11A 1 1636187 1636187 DOHH2_HAEMATOPO... 37 Intron SNP C T uc009vks.2 CDK11B_uc001ags... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 DOHH2_HAEMATOPO... 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 DOHH2_HAEMATOPO... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 DOHH2_HAEMATOPO... 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CXCL12 10 44873992 44873993 DOHH2_HAEMATOPO... 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
DDR2 1 162750211 162750212 DOHH2_HAEMATOPO... 37 3'UTR Del TT - uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap...
DTX1 12 113495897 113495897 DOHH2_HAEMATOPO... 37 5'UTR SNP G C uc001tuk.1 Hybrid_Cap... view
EDN1 6 12290729 12290729 DOHH2_HAEMATOPO... 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EIF4E 4 99808137 99808141 DOHH2_HAEMATOPO... 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
EP300 22 41574970 41574972 DOHH2_HAEMATOPO... 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 DOHH2_HAEMATOPO... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPS15 1 51822220 51822220 DOHH2_HAEMATOPO... 37 3'UTR Del A - uc001csq.1 EPS15_uc009vyz.... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 DOHH2_HAEMATOPO... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 DOHH2_HAEMATOPO... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 DOHH2_HAEMATOPO... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLT1 p.S1277N 13 28877491 28877491 DOHH2_HAEMATOPO... 37 Missense_Mutation SNP C T uc001usb.3 FLT1_uc010aap.2... Hybrid_Cap... view
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 DOHH2_HAEMATOPO... 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FN1 2 216244182 216244185 DOHH2_HAEMATOPO... 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GRIA3 X 122318386 122318387 DOHH2_HAEMATOPO... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
HIF1A 14 62213929 62213930 DOHH2_HAEMATOPO... 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 DOHH2_HAEMATOPO... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
IKZF3 p.N160S 17 37947782 37947782 DOHH2_HAEMATOPO... 37 Missense_Mutation SNP T C uc002hsu.2 IKZF3_uc002htd.... Hybrid_Cap... view
ILK 11 6630029 6630029 DOHH2_HAEMATOPO... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 DOHH2_HAEMATOPO... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KLK7 19 51480672 51480675 DOHH2_HAEMATOPO... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LATS2 13 21548985 21548985 DOHH2_HAEMATOPO... 37 3'UTR SNP G A uc009zzs.2 LATS2_uc001unr.... Hybrid_Cap... view
LATS2 p.P551L 13 21562267 21562267 DOHH2_HAEMATOPO... 37 Missense_Mutation SNP G A uc009zzs.2 LATS2_uc001unr.... Hybrid_Cap... view
MAF 16 79628537 79628537 DOHH2_HAEMATOPO... 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 DOHH2_HAEMATOPO... 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 DOHH2_HAEMATOPO... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 DOHH2_HAEMATOPO... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K4 p.A1199del 6 161519351 161519353 DOHH2_HAEMATOPO... 37 In_Frame_Del Del CTG - uc003qtn.2 MAP3K4_uc010kkc... Hybrid_Cap...
MAP3K9 p.A676_splice 14 71200516 71200516 DOHH2_HAEMATOPO... 37 Splice_Site_SNP SNP C G uc001xml.2 MAP3K9_uc010ttk... Hybrid_Cap... view
MAPKAPK3 3 50685575 50685575 DOHH2_HAEMATOPO... 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MECOM 3 169381262 169381262 DOHH2_HAEMATOPO... 37 5'UTR SNP G C rs10581416 uc011bpj.1 MECOM_uc011bpk.... Hybrid_Cap... view
MGA 15 42059619 42059619 DOHH2_HAEMATOPO... 37 3'UTR SNP G T uc010ucy.1 MGA_uc010ucz.1_... Hybrid_Cap... view
MLH1 p.V113V 3 37045924 37045924 DOHH2_HAEMATOPO... 37 Silent SNP T A uc003cgl.2 MLH1_uc011aye.1... Hybrid_Cap... view
MLLT6 17 36881873 36881873 DOHH2_HAEMATOPO... 37 3'UTR Del C - uc002hqi.3 MLLT6_uc002hqk.... Hybrid_Cap...
MSH3 p.PPA66del 5 79950742 79950750 DOHH2_HAEMATOPO... 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MYC p.L164V 8 128750953 128750953 DOHH2_HAEMATOPO... 37 Missense_Mutation SNP C G uc003ysi.2 MYC_uc003ysh.1_... Hybrid_Cap... view
MYST4 p.E1104del 10 76781906 76781908 DOHH2_HAEMATOPO... 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NCAM1 11 112832307 112832308 DOHH2_HAEMATOPO... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 DOHH2_HAEMATOPO... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279837 46279839 DOHH2_HAEMATOPO... 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NCOA3 20 46282339 46282340 DOHH2_HAEMATOPO... 37 3'UTR Ins - AT uc002xtk.2 NCOA3_uc002xtl.... Hybrid_Cap...
NEK1 p.L850R 4 170384432 170384432 DOHH2_HAEMATOPO... 37 Missense_Mutation SNP A C uc003isd.1 NEK1_uc003isb.1... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 DOHH2_HAEMATOPO... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 DOHH2_HAEMATOPO... 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NLK p.P41del 17 26370014 26370016 DOHH2_HAEMATOPO... 37 In_Frame_Del Del CCT - uc010crj.2 NLK_uc010cri.1_... Hybrid_Cap...
NPM1 5 170837734 170837734 DOHH2_HAEMATOPO... 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 DOHH2_HAEMATOPO... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 DOHH2_HAEMATOPO... 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP98 11 3697323 3697323 DOHH2_HAEMATOPO... 37 3'UTR SNP A C uc001lyh.2 NUP98_uc001lyi.... Hybrid_Cap... view
PAX3 2 223066017 223066018 DOHH2_HAEMATOPO... 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 DOHH2_HAEMATOPO... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP p.V486fs 1 144917828 144917828 DOHH2_HAEMATOPO... 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PER1 p.L778W 17 8048197 8048198 DOHH2_HAEMATOPO... 37 Missense_Mutation DNP AG CA uc002gkd.2 PER1_uc010cns.2... Hybrid_Cap...
PGR 11 100933598 100933599 DOHH2_HAEMATOPO... 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2A 11 17111198 17111199 DOHH2_HAEMATOPO... 37 3'UTR Del GT - uc001mmq.3 PIK3C2A_uc009yg... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 DOHH2_HAEMATOPO... 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PKN2 p.L384del 1 89250482 89250484 DOHH2_HAEMATOPO... 37 In_Frame_Del Del TCT - uc001dmn.2 PKN2_uc001dmm.1... Hybrid_Cap...
PML 15 74328431 74328431 DOHH2_HAEMATOPO... 37 Intron SNP A G uc002awv.2 PML_uc002awm.2_... Hybrid_Cap... view
PMS1 2 190670539 190670540 DOHH2_HAEMATOPO... 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PPP3R1 p.F15_splice 2 68415824 68415824 DOHH2_HAEMATOPO... 37 Splice_Site_SNP SNP T A uc002sei.1 Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 DOHH2_HAEMATOPO... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RAGE 14 102695502 102695502 DOHH2_HAEMATOPO... 37 3'UTR SNP G A uc001ylm.2 RAGE_uc010txv.1... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 DOHH2_HAEMATOPO... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RPS6KL1 14 75373626 75373627 DOHH2_HAEMATOPO... 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SLC6A8 X 152957656 152957657 DOHH2_HAEMATOPO... 37 Intron Ins - A uc004fib.3 SLC6A8_uc004fic... Hybrid_Cap...
STK25 2 242435659 242435662 DOHH2_HAEMATOPO... 37 Intron Del AAGG - rs3215138;rs75497042 uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap...
TCF21 6 134210497 134210498 DOHH2_HAEMATOPO... 37 5'UTR Ins - TCTC rs35199378 uc003qei.3 TCF21_uc003qej.... Hybrid_Cap...
TEC 4 48139307 48139310 DOHH2_HAEMATOPO... 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TMEM123 11 102269398 102269398 DOHH2_HAEMATOPO... 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNKS2 10 93622951 93622959 DOHH2_HAEMATOPO... 37 3'UTR Del GTTTT... - rs115539654 uc001khp.2 Hybrid_Cap...
TP63 3 189507518 189507519 DOHH2_HAEMATOPO... 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRPS1 8 116635872 116635873 DOHH2_HAEMATOPO... 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN 2 179391639 179391640 DOHH2_HAEMATOPO... 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.V2919L 2 179634553 179634553 DOHH2_HAEMATOPO... 37 Missense_Mutation SNP C A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 DOHH2_HAEMATOPO... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...