Annotation Summary for Cell Line: FTC-133  

Cell line primary name: FTC-133
Cell line aliases:
Gender: M
Site Primary: thyroid
Histology: carcinoma
Hist Subtype1: follicular_carcinoma
Notes: Metastatic pair: FTC-133 and FTC-238 are from the same patient. FTC-133 was derived from the primary tumor.
Source: ECACC
Expression arrays: CRAZY_p_NCLE_RNA10_HG-U133_Plus_2_C11_569508
SNP arrays: VAULT_p_NCLE_DNAAffy14_GenomeWideSNP_6_C12_698618
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in FTC-133

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ACACB p.R1706Q 12 109680336 109680336 FTC133_THYROID 37 Missense_Mutation SNP G A uc001tob.2 ACACB_uc001toc.... Hybrid_Cap... view
ADAM28 8 24211994 24211997 FTC133_THYROID 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS18 16 77317664 77317664 FTC133_THYROID 37 3'UTR SNP C G uc002ffc.3 Hybrid_Cap... view
ADCK1 14 78390632 78390637 FTC133_THYROID 37 Intron Del AAACT... - rs78274857;rs74969652 uc001xui.2 ADCK1_uc010tvo.... Hybrid_Cap...
AFF1 p.M1067V 4 88053448 88053448 FTC133_THYROID 37 Missense_Mutation SNP A G uc011ccz.1 AFF1_uc003hqj.3... Hybrid_Cap... view
AKAP6 p.R1876C 14 33292645 33292645 FTC133_THYROID 37 Missense_Mutation SNP C T uc001wrq.2 Hybrid_Cap... view
ALK p.A1148V 2 29445390 29445390 FTC133_THYROID 37 Missense_Mutation SNP G A uc002rmy.2 ALK_uc010ymo.1_... Hybrid_Cap... view
ARID1A 1 27107263 27107264 FTC133_THYROID 37 3'UTR Ins - C rs3841356 uc001bmv.1 ARID1A_uc001bmu... Hybrid_Cap...
CACNA1F p.815_815E>EE X 49076224 49076225 FTC133_THYROID 37 In_Frame_Ins Ins - TCC uc004dnb.2 CACNA1F_uc010ni... Hybrid_Cap...
CAMK2G 10 75599324 75599324 FTC133_THYROID 37 Intron SNP C T uc001jvv.1 CAMK2G_uc001jvm... Hybrid_Cap... view
CARD11 7 2946269 2946269 FTC133_THYROID 37 3'UTR SNP G A uc003smv.2 Hybrid_Cap... view
CDK11B 1 1654066 1654068 FTC133_THYROID 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CDK6 p.R168H 7 92354974 92354974 FTC133_THYROID 37 Missense_Mutation SNP C T uc011khw.1 CDK6_uc010lez.2... Hybrid_Cap... view
CHD8 14 21853630 21853630 FTC133_THYROID 37 3'UTR Del T - rs78520772 uc001was.1 CHD8_uc001war.1... Hybrid_Cap...
CHD8 p.S2135fs 14 21854277 21854278 FTC133_THYROID 37 Frame_Shift_Del Del CT - uc001was.1 CHD8_uc001war.1... Hybrid_Cap...
CLPTM1 p.V590I 19 45495913 45495913 FTC133_THYROID 37 Missense_Mutation SNP G A uc002pai.2 CLPTM1_uc010xxf... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 FTC133_THYROID 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CPAMD8 p.T1522M 19 17014417 17014417 FTC133_THYROID 37 Missense_Mutation SNP G A uc002nfb.2 CPAMD8_uc002nfd... Hybrid_Cap... view
CREB3L2 p.T100del 7 137612914 137612916 FTC133_THYROID 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CTBP2 p.K974fs 10 126678123 126678123 FTC133_THYROID 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
CUBN p.G1267V 10 17085855 17085855 FTC133_THYROID 37 Missense_Mutation SNP C A uc001ioo.2 Hybrid_Cap... view
DNAH8 6 38952247 38952248 FTC133_THYROID 37 Intron Del CA - uc003ooe.1 DNAH8_uc003oog.... Hybrid_Cap...
DST 6 56480217 56480217 FTC133_THYROID 37 Intron SNP A C uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
EML4 p.V588I 2 42530364 42530364 FTC133_THYROID 37 Missense_Mutation SNP G A uc002rsi.2 EML4_uc010fap.2... Hybrid_Cap... view
EPHA4 2 222290623 222290624 FTC133_THYROID 37 3'UTR Ins - T uc002vmq.2 EPHA4_uc002vmr.... Hybrid_Cap...
ERBB2 p.A830V 17 37881160 37881160 FTC133_THYROID 37 Missense_Mutation SNP C T uc002hso.2 ERBB2_uc002hsm.... Hybrid_Cap... view
ERBB4 p.V748L 2 212483961 212483961 FTC133_THYROID 37 Missense_Mutation SNP C A uc002veg.1 ERBB4_uc002veh.... Hybrid_Cap... view
ERCC4 p.T809M 16 14041879 14041879 FTC133_THYROID 37 Missense_Mutation SNP C T uc002dce.2 ERCC4_uc010uyz.... Hybrid_Cap... view
ETV1 7 14028708 14028708 FTC133_THYROID 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FLI1 11 128638217 128638217 FTC133_THYROID 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 FTC133_THYROID 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FN1 p.L1767L 2 216245669 216245669 FTC133_THYROID 37 Silent SNP G A uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap... view
GLI3 p.R862C 7 42006087 42006087 FTC133_THYROID 37 Missense_Mutation SNP G A uc011kbh.1 GLI3_uc011kbg.1... Hybrid_Cap... view
GRIA3 X 122318386 122318387 FTC133_THYROID 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 FTC133_THYROID 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A p.P46Q 14 62187198 62187198 FTC133_THYROID 37 Missense_Mutation SNP C A uc001xfs.2 HIF1A_uc010tsc.... Hybrid_Cap... view
HIF1A 14 62213929 62213930 FTC133_THYROID 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1B p.Q182* 17 36099431 36099431 FTC133_THYROID 37 Nonsense_Mutation SNP G A uc002hok.3 HNF1B_uc010wdi.... Hybrid_Cap... view
HOXA13 7 27237762 27237762 FTC133_THYROID 37 3'UTR SNP G A uc003szb.1 Hybrid_Cap... view
HSP90AA1 14 102547769 102547770 FTC133_THYROID 37 3'UTR Ins - CA rs72520876 uc001ykv.3 HSP90AA1_uc001y... Hybrid_Cap...
HSP90AA1 p.P115S 14 102568235 102568235 FTC133_THYROID 37 Missense_Mutation SNP G A uc001ykv.3 Hybrid_Cap... view
HSP90B1 12 104341645 104341648 FTC133_THYROID 37 3'UTR Del ACTG - rs2307842 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 FTC133_THYROID 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INHBA 7 41729111 41729112 FTC133_THYROID 37 3'UTR Ins - T rs116913029 uc003thq.2 INHBA_uc003thr.... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 FTC133_THYROID 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KDR p.P230L 4 55980402 55980402 FTC133_THYROID 37 Missense_Mutation SNP G A uc003has.2 KDR_uc003hat.1_... Hybrid_Cap... view
KIAA1409 p.A1063V 14 94069729 94069729 FTC133_THYROID 37 Missense_Mutation SNP C T uc001ybv.1 KIAA1409_uc001y... Hybrid_Cap... view
KIAA1804 p.R553Q 1 233507889 233507889 FTC133_THYROID 37 Missense_Mutation SNP G A uc001hvt.3 KIAA1804_uc001h... Hybrid_Cap... view
KLF6 10 3821635 3821635 FTC133_THYROID 37 3'UTR SNP G C rs56987769 uc001iha.2 KLF6_uc010qaj.1... Hybrid_Cap... view
KLK7 19 51480672 51480675 FTC133_THYROID 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LAMA1 p.L587R 18 7036065 7036065 FTC133_THYROID 37 Missense_Mutation SNP A C uc002knm.2 LAMA1_uc010wzj.... Hybrid_Cap... view
LRGUK p.T250A 7 133842865 133842865 FTC133_THYROID 37 Missense_Mutation SNP A G uc003vrm.1 Hybrid_Cap... view
LRP1 p.W383R 12 57548404 57548404 FTC133_THYROID 37 Missense_Mutation SNP T C uc001snd.2 LRP1_uc001snc.1... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 FTC133_THYROID 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K3 p.P274L 17 21215500 21215500 FTC133_THYROID 37 Missense_Mutation SNP C T uc002gys.2 MAP2K3_uc002gyt... Hybrid_Cap... view
MAP2K6 17 67516341 67516341 FTC133_THYROID 37 Intron Del T - uc002jij.2 MAP2K6_uc002jii... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 FTC133_THYROID 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 FTC133_THYROID 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K7 6 91226170 91226170 FTC133_THYROID 37 3'UTR Del A - uc003pnz.1 MAP3K7_uc003pny... Hybrid_Cap...
MAP3K9 p.T312M 14 71227785 71227785 FTC133_THYROID 37 Missense_Mutation SNP G A uc001xml.2 MAP3K9_uc010ttk... Hybrid_Cap... view
MAPK11 22 50704886 50704886 FTC133_THYROID 37 Intron SNP C T uc003bkr.2 MAPK11_uc010hax... Hybrid_Cap... view
MAPKBP1 p.S384L 15 42106900 42106900 FTC133_THYROID 37 Missense_Mutation SNP C T uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap... view
MCF2 X 138724842 138724842 FTC133_THYROID 37 Intron Del A - uc011mwo.1 MCF2_uc004fau.2... Hybrid_Cap...
MLL3 p.Q2177* 7 151878416 151878416 FTC133_THYROID 37 Nonsense_Mutation SNP G A uc003wla.2 MLL3_uc003wkz.2... Hybrid_Cap... view
MSH6 p.K1045fs 2 48028257 48028257 FTC133_THYROID 37 Frame_Shift_Del Del G - uc002rwd.3 MSH6_uc002rwc.2... Hybrid_Cap...
MSMB 10 51562416 51562416 FTC133_THYROID 37 3'UTR SNP C T rs10611 uc001jiq.2 PARG_uc001jih.2... Hybrid_Cap... view
MST1R p.G911V 3 49933458 49933458 FTC133_THYROID 37 Missense_Mutation SNP C A uc003cxy.3 MST1R_uc011bdc.... Hybrid_Cap... view
NAV3 p.K501R 12 78400820 78400820 FTC133_THYROID 37 Missense_Mutation SNP A G uc001syp.2 NAV3_uc001syo.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 FTC133_THYROID 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 FTC133_THYROID 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAPD3 p.E1404K 11 134026955 134026955 FTC133_THYROID 37 Missense_Mutation SNP C T uc001qhd.1 NCAPD3_uc010scm... Hybrid_Cap... view
NCOA1 p.S192G 2 24914391 24914391 FTC133_THYROID 37 Missense_Mutation SNP A G uc002rfk.2 NCOA1_uc010eye.... Hybrid_Cap... view
NEDD9 p.Q597K 6 11190313 11190313 FTC133_THYROID 37 Missense_Mutation SNP G T uc003mzv.2 NEDD9_uc010joz.... Hybrid_Cap... view
NF1 p.C167* 17 29496930 29496930 FTC133_THYROID 37 Nonsense_Mutation SNP T A uc002hgg.2 NF1_uc002hge.1_... Hybrid_Cap... view
NFIA 1 61921185 61921186 FTC133_THYROID 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NFKB1 p.R920* 4 103537599 103537599 FTC133_THYROID 37 Nonsense_Mutation SNP C T uc011cep.1 NFKB1_uc011ceq.... Hybrid_Cap... view
NLRP1 p.R35M 17 5487174 5487174 FTC133_THYROID 37 Missense_Mutation SNP C A uc002gci.2 NLRP1_uc002gcg.... Hybrid_Cap... view
NOS2 p.V686A 17 26094841 26094841 FTC133_THYROID 37 Missense_Mutation SNP A G uc002gzu.2 NOS2_uc010wab.1... Hybrid_Cap... view
NOS3 p.R678W 7 150704284 150704284 FTC133_THYROID 37 Missense_Mutation SNP C T uc003wif.2 NOS3_uc011kuy.1... Hybrid_Cap... view
NOTCH4 p.15_16LL>L 6 32191659 32191661 FTC133_THYROID 37 In_Frame_Del Del AGC - uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap...
NPR1 1 153665919 153665920 FTC133_THYROID 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 FTC133_THYROID 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NTRK2 p.V622I 9 87563476 87563476 FTC133_THYROID 37 Missense_Mutation SNP G A uc004anz.1 NTRK2_uc004any.... Hybrid_Cap... view
NUMA1 p.A175V 11 71730600 71730600 FTC133_THYROID 37 Missense_Mutation SNP G A uc001orl.1 NUMA1_uc001ork.... Hybrid_Cap... view
OBSCN p.G2714S 1 228468440 228468440 FTC133_THYROID 37 Missense_Mutation SNP G A uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
ODZ1 p.R1734H X 123539071 123539071 FTC133_THYROID 37 Missense_Mutation SNP C T uc010nqy.2 ODZ1_uc011muj.1... Hybrid_Cap... view
OR4E2 p.F256L 14 22134064 22134064 FTC133_THYROID 37 Missense_Mutation SNP C A uc010tmd.1 Hybrid_Cap... view
PAX3 2 223158653 223158653 FTC133_THYROID 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP p.Q1665fs 1 144873963 144873963 FTC133_THYROID 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.V486fs 1 144917828 144917828 FTC133_THYROID 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDGFRA 4 55131002 55131002 FTC133_THYROID 37 Intron Del A - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PDZRN4 p.N102D 12 41900315 41900315 FTC133_THYROID 37 Missense_Mutation SNP A G uc010skn.1 PDZRN4_uc001rmq... Hybrid_Cap... view
PIKFYVE p.P1521H 2 209201603 209201603 FTC133_THYROID 37 Missense_Mutation SNP C A uc002vcz.2 Hybrid_Cap... view
PIP5K1C p.V235I 19 3653506 3653506 FTC133_THYROID 37 Missense_Mutation SNP C T uc010xhr.1 PIP5K1C_uc002ly... Hybrid_Cap... view
PKN1 p.A548V 19 14574769 14574769 FTC133_THYROID 37 Missense_Mutation SNP C T uc002myq.2 PKN1_uc002myp.2... Hybrid_Cap... view
PPM1E p.G382* 17 57050220 57050220 FTC133_THYROID 37 Nonsense_Mutation SNP G T uc002iwx.2 PPM1E_uc010ddd.... Hybrid_Cap... view
PREX2 p.L147S 8 68934374 68934374 FTC133_THYROID 37 Missense_Mutation SNP T C uc003xxv.1 PREX2_uc003xxu.... Hybrid_Cap... view
PRKACG 9 71627751 71627752 FTC133_THYROID 37 3'UTR Ins - GG rs3841198 uc004agy.2 Hybrid_Cap...
PRKCG p.V68_splice 19 54387414 54387414 FTC133_THYROID 37 Splice_Site_SNP SNP G C uc010yeg.1 PRKCG_uc010eqz.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 FTC133_THYROID 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTEN p.R130* 10 89692904 89692904 FTC133_THYROID 37 Nonsense_Mutation SNP C T uc001kfb.2 Hybrid_Cap... view
PTPN1 p.K197E 20 49195053 49195053 FTC133_THYROID 37 Missense_Mutation SNP A G uc002xvl.2 PTPN1_uc010zys.... Hybrid_Cap... view
RB1 p.IL517del 13 48955432 48955437 FTC133_THYROID 37 In_Frame_Del Del GATTC... - uc001vcb.2 Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 FTC133_THYROID 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RGL3 19 11527163 11527163 FTC133_THYROID 37 Intron SNP A G uc002mro.2 RGL3_uc002mrn.2... Hybrid_Cap... view
RGS22 p.749_750MK>IE 8 101020716 101020717 FTC133_THYROID 37 Missense_Mutation DNP TC CT rs79298856 uc003yjb.1 RGS22_uc003yja.... Hybrid_Cap...
RPS6KA5 14 91360733 91360734 FTC133_THYROID 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
RPS6KL1 14 75373626 75373627 FTC133_THYROID 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SCARA5 p.V490M 8 27729471 27729471 FTC133_THYROID 37 Missense_Mutation SNP C T uc003xgj.2 SCARA5_uc010luz... Hybrid_Cap... view
SEPT5 p.A309V 22 19709456 19709456 FTC133_THYROID 37 Missense_Mutation SNP C T uc002zpv.1 SEPT5_uc002zpw.... Hybrid_Cap... view
SP1 p.G240R 12 53776449 53776449 FTC133_THYROID 37 Missense_Mutation SNP G C uc001scw.2 SP1_uc010sog.1_... Hybrid_Cap... view
SPTAN1 9 131390346 131390346 FTC133_THYROID 37 Intron SNP C A uc004bvm.3 SPTAN1_uc004bvl... Hybrid_Cap... view
STK17B p.H79R 2 197021262 197021262 FTC133_THYROID 37 Missense_Mutation SNP T C uc002utk.2 STK17B_uc010fsh... Hybrid_Cap... view
STK31 7 23872024 23872025 FTC133_THYROID 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
STK38L p.L127F 12 27462116 27462116 FTC133_THYROID 37 Missense_Mutation SNP C T uc001rhr.2 STK38L_uc001rhs... Hybrid_Cap... view
TLK1 2 171850178 171850179 FTC133_THYROID 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TPR p.D612G 1 186325471 186325471 FTC133_THYROID 37 Missense_Mutation SNP T C uc001grv.2 Hybrid_Cap... view
TRRAP p.A1043T 7 98524941 98524941 FTC133_THYROID 37 Missense_Mutation SNP G A uc003upp.2 TRRAP_uc011kis.... Hybrid_Cap... view
TRRAP p.D2600G 7 98569549 98569549 FTC133_THYROID 37 Missense_Mutation SNP A G uc003upp.2 TRRAP_uc011kis.... Hybrid_Cap... view
TRRAP p.P3747L 7 98609103 98609103 FTC133_THYROID 37 Missense_Mutation SNP C T uc003upp.2 TRRAP_uc011kis.... Hybrid_Cap... view
TSHR p.A471T 14 81609813 81609813 FTC133_THYROID 37 Missense_Mutation SNP G A uc001xvd.1 Hybrid_Cap... view
TTN p.R20911W 2 179440424 179440424 FTC133_THYROID 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.S1904* 2 179640880 179640880 FTC133_THYROID 37 Nonsense_Mutation SNP G C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 FTC133_THYROID 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...