Annotation Summary for Cell Line: FU-OV-1  

Cell line primary name: FU-OV-1
Cell line aliases:
Gender: F
Site Primary: ovary
Histology: carcinoma
Hist Subtype1: serous_carcinoma
Notes:
Source: DSMZ
Expression arrays: METIS_p_NCLE_RNA1_Human_U133_Plus_2.0_E12_240968
SNP arrays: LIMPS_p_NCLE_DNA2N_GenomeWideSNP_6_C10_246676
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in FU-OV-1

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM28 8 24211994 24211997 FUOV1_OVARY 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 FUOV1_OVARY 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK1 4 113347609 113347610 FUOV1_OVARY 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 FUOV1_OVARY 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ASPH p.A264_splice 8 62550924 62550925 FUOV1_OVARY 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
AURKC 19 57742494 57742507 FUOV1_OVARY 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BAX 19 49464508 49464509 FUOV1_OVARY 37 3'UTR Del TT - uc002plf.1 BAX_uc002plg.1_... Hybrid_Cap...
BIRC6 p.V4103L 2 32768323 32768323 FUOV1_OVARY 37 Missense_Mutation SNP G T uc010ezu.2 Hybrid_Cap... view
BRSK2 11 1482338 1482338 FUOV1_OVARY 37 3'UTR SNP C T uc001ltm.2 BRSK2_uc001lti.... Hybrid_Cap... view
BTRC p.R598Q 10 103310592 103310592 FUOV1_OVARY 37 Missense_Mutation SNP G A uc001kta.2 BTRC_uc001ktb.2... Hybrid_Cap... view
CACNB2 10 18828721 18828722 FUOV1_OVARY 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CARD10 p.KE272del 22 37906309 37906314 FUOV1_OVARY 37 In_Frame_Del Del CTCCT... - uc003asx.1 CARD10_uc003ast... Hybrid_Cap...
CARD14 p.E490* 17 78169101 78169101 FUOV1_OVARY 37 Nonsense_Mutation SNP G T uc002jxw.1 CARD14_uc002jxt... Hybrid_Cap... view
CDK11B 1 1654066 1654068 FUOV1_OVARY 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CDKL5 p.R550Q X 18622693 18622693 FUOV1_OVARY 37 Missense_Mutation SNP G A uc004cym.2 CDKL5_uc004cyn.... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 FUOV1_OVARY 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 FUOV1_OVARY 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSF1R 5 149433433 149433433 FUOV1_OVARY 37 3'UTR SNP T C uc003lrl.2 CSF1R_uc011dcd.... Hybrid_Cap... view
DGKB 7 14216345 14216346 FUOV1_OVARY 37 Intron Ins - AGACT uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap...
DOCK3 p.Y1341H 3 51387737 51387737 FUOV1_OVARY 37 Missense_Mutation SNP T C uc011bds.1 Hybrid_Cap... view
DYRK1A 21 38884966 38884967 FUOV1_OVARY 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EPHA4 2 222290623 222290624 FUOV1_OVARY 37 3'UTR Ins - T uc002vmq.2 EPHA4_uc002vmr.... Hybrid_Cap...
EPHA6 3 97367230 97367231 FUOV1_OVARY 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ERC1 12 1136997 1136997 FUOV1_OVARY 37 5'UTR SNP C T uc001qjb.2 ERC1_uc001qiz.2... Hybrid_Cap... view
FGFR3 4 1809128 1809129 FUOV1_OVARY 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 FUOV1_OVARY 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNA X 153577133 153577134 FUOV1_OVARY 37 3'UTR Ins - AG rs71733538 uc004fkk.2 FLNA_uc004fki.2... Hybrid_Cap...
FLNB p.D1264E 3 58110126 58110126 FUOV1_OVARY 37 Missense_Mutation SNP C A uc010hne.2 FLNB_uc003djj.2... Hybrid_Cap... view
FN1 2 216244182 216244185 FUOV1_OVARY 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FNBP1 p.S336Y 9 132686286 132686286 FUOV1_OVARY 37 Missense_Mutation SNP G T uc004byw.1 FNBP1_uc011mbv.... Hybrid_Cap... view
FRS2 p.P401L 12 69968410 69968410 FUOV1_OVARY 37 Missense_Mutation SNP C T uc001suy.2 FRS2_uc001suz.2... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 FUOV1_OVARY 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 FUOV1_OVARY 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIK1 21 30909456 30909456 FUOV1_OVARY 37 3'UTR SNP G A uc011acs.1 GRIK1_uc002ynn.... Hybrid_Cap... view
GUCY2C p.G523S 12 14804931 14804931 FUOV1_OVARY 37 Missense_Mutation SNP C T uc001rcd.2 Hybrid_Cap... view
GUCY2C 12 14827464 14827466 FUOV1_OVARY 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HEPH p.S67C X 65392220 65392220 FUOV1_OVARY 37 Missense_Mutation SNP C G uc011moz.1 HEPH_uc004dwn.2... Hybrid_Cap... view
HIF1A 14 62213929 62213930 FUOV1_OVARY 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 FUOV1_OVARY 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 FUOV1_OVARY 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 FUOV1_OVARY 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
JAG2 p.G338D 14 105618301 105618301 FUOV1_OVARY 37 Missense_Mutation SNP C T uc001yqg.2 JAG2_uc001yqf.2... Hybrid_Cap... view
KLK7 19 51480672 51480675 FUOV1_OVARY 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LRP1B p.R2165W 2 141458125 141458125 FUOV1_OVARY 37 Missense_Mutation SNP G A uc002tvj.1 Hybrid_Cap... view
LRP6 12 12419760 12419760 FUOV1_OVARY 37 5'UTR SNP C T uc001rah.3 LRP6_uc010shl.1... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 FUOV1_OVARY 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 FUOV1_OVARY 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 FUOV1_OVARY 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K5 6 136878751 136878752 FUOV1_OVARY 37 3'UTR Ins - T rs34705939;rs79903899 uc003qhc.2 MAP3K5_uc011edj... Hybrid_Cap...
MYLK p.E1066del 3 123419117 123419119 FUOV1_OVARY 37 In_Frame_Del Del TTC - rs72491150 uc003ego.2 MYLK_uc011bjw.1... Hybrid_Cap...
MYLK3 p.D435H 16 46766279 46766279 FUOV1_OVARY 37 Missense_Mutation SNP C G uc002eei.3 MYLK3_uc010vge.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 FUOV1_OVARY 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 FUOV1_OVARY 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279864 46279866 FUOV1_OVARY 37 In_Frame_Del Del CAA - rs1132443;rs28529067 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 FUOV1_OVARY 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NF1 p.Q1033R 17 29557385 29557385 FUOV1_OVARY 37 Missense_Mutation SNP A G uc002hgg.2 NF1_uc002hgh.2_... Hybrid_Cap... view
NF1 p.F1037C 17 29557397 29557397 FUOV1_OVARY 37 Missense_Mutation SNP T G uc002hgg.2 NF1_uc002hgh.2_... Hybrid_Cap... view
NFIA 1 61921185 61921186 FUOV1_OVARY 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NPR1 1 153665919 153665920 FUOV1_OVARY 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NPRL2 3 50384978 50384978 FUOV1_OVARY 37 3'UTR Del C - rs75013672 uc003daj.1 ZMYND10_uc003da... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 FUOV1_OVARY 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NTSR1 p.E282K 20 61386166 61386166 FUOV1_OVARY 37 Missense_Mutation SNP G A uc002ydf.2 Hybrid_Cap... view
NUMA1 p.A790V 11 71726180 71726180 FUOV1_OVARY 37 Missense_Mutation SNP G A uc001orl.1 NUMA1_uc009ysw.... Hybrid_Cap... view
PAK4 p.D389Y 19 39665637 39665637 FUOV1_OVARY 37 Missense_Mutation SNP G T uc002okj.1 PAK4_uc002okl.1... Hybrid_Cap... view
PAK6 p.R334H 15 40564567 40564567 FUOV1_OVARY 37 Missense_Mutation SNP G A uc010bbl.2 PAK6_uc010bbm.2... Hybrid_Cap... view
PAX3 2 223066017 223066018 FUOV1_OVARY 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 FUOV1_OVARY 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP p.L601fs 1 144915624 144915624 FUOV1_OVARY 37 Frame_Shift_Del Del G - rs1778112 uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.E243fs 1 144923729 144923729 FUOV1_OVARY 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.R32Q 1 145075768 145075768 FUOV1_OVARY 37 Missense_Mutation SNP C T uc001emh.2 NBPF10_uc009wir... Hybrid_Cap... view
PDGFRA 4 55131002 55131002 FUOV1_OVARY 37 Intron Del A - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PGGT1B 5 114548071 114548072 FUOV1_OVARY 37 3'UTR Ins - C uc003kqw.3 PGGT1B_uc003kqx... Hybrid_Cap...
PGR 11 100933598 100933599 FUOV1_OVARY 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2A 11 17111198 17111199 FUOV1_OVARY 37 3'UTR Del GT - uc001mmq.3 PIK3C2A_uc009yg... Hybrid_Cap...
PIP4K2A 10 22825895 22825895 FUOV1_OVARY 37 3'UTR SNP C A rs117970263 uc001irl.3 PIP4K2A_uc010qc... Hybrid_Cap... view
PLCG2 p.G191del 16 81904462 81904464 FUOV1_OVARY 37 In_Frame_Del Del AGG - uc002fgt.2 PLCG2_uc010chg.... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 FUOV1_OVARY 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG2 p.F741Y 4 82010929 82010929 FUOV1_OVARY 37 Missense_Mutation SNP A T uc003hmh.2 PRKG2_uc011ccf.... Hybrid_Cap... view
RASGRF1 15 79277150 79277151 FUOV1_OVARY 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RBPJ 4 26431822 26431822 FUOV1_OVARY 37 Intron Del A - rs76214390 uc003grx.1 RBPJ_uc003gry.1... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 FUOV1_OVARY 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RGL2 6 33261359 33261359 FUOV1_OVARY 37 Intron SNP C T uc003odv.2 RGL2_uc003odu.2... Hybrid_Cap... view
ROBO1 3 78647853 78647853 FUOV1_OVARY 37 3'UTR SNP A C uc003dqe.2 ROBO1_uc003dqb.... Hybrid_Cap... view
ROCK2 2 11323416 11323416 FUOV1_OVARY 37 3'UTR SNP A G uc002rbd.1 Hybrid_Cap... view
SEPT6 p.S233N X 118783982 118783982 FUOV1_OVARY 37 Missense_Mutation SNP C T uc011mtw.1 SEPT6_uc010nqk.... Hybrid_Cap... view
SEPT9 17 75494787 75494788 FUOV1_OVARY 37 3'UTR Ins - C rs5822173 uc002jts.3 SEPT9_uc010wtk.... Hybrid_Cap...
SLC45A3 p.222_234ALGPTEPAEGLSA>A 1 205632218 205632253 FUOV1_OVARY 37 In_Frame_Del Del GCCGA... - uc001hda.1 SLC45A3_uc010pr... Hybrid_Cap...
STK25 2 242435659 242435662 FUOV1_OVARY 37 Intron Del AAGG - rs3215138;rs75497042 uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap...
STK31 7 23872024 23872025 FUOV1_OVARY 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TAB2 p.T376M 6 149700178 149700178 FUOV1_OVARY 37 Missense_Mutation SNP C T uc003qmj.2 TAB2_uc011eec.1... Hybrid_Cap... view
TEC 4 48139307 48139310 FUOV1_OVARY 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TMEM123 11 102269398 102269398 FUOV1_OVARY 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TOP2B p.E1227D 3 25654096 25654096 FUOV1_OVARY 37 Missense_Mutation SNP C G uc003cdj.2 TOP2B_uc011awn.... Hybrid_Cap... view
TP53 p.H179D 17 7578395 7578395 FUOV1_OVARY 37 Missense_Mutation SNP G C uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM33 1 114940212 114940212 FUOV1_OVARY 37 3'UTR Del T - uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRPM7 p.L228* 15 50929768 50929768 FUOV1_OVARY 37 Nonsense_Mutation SNP A T uc001zyt.3 TRPM7_uc010bew.... Hybrid_Cap... view
TRPS1 8 116635872 116635873 FUOV1_OVARY 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN 2 179391639 179391640 FUOV1_OVARY 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.R30283* 2 179404241 179404241 FUOV1_OVARY 37 Nonsense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
ULK4 p.W599* 3 41860966 41860966 FUOV1_OVARY 37 Nonsense_Mutation SNP C T uc003ckv.3 ULK4_uc003ckw.2... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 FUOV1_OVARY 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
VRK3 p.SCSPQKT127del 19 50510972 50510992 FUOV1_OVARY 37 In_Frame_Del Del CTGGT... - rs117711287;rs117077533 uc002prg.2 VRK3_uc002prh.1... Hybrid_Cap...
WRN p.T781I 8 30973938 30973938 FUOV1_OVARY 37 Missense_Mutation SNP C T rs17847568 uc003xio.3 WRN_uc010lvk.2_... Hybrid_Cap... view