Annotation Summary for Cell Line: HCC1143  

Cell line primary name: HCC1143
Cell line aliases:
Gender: F
Site Primary: breast
Histology: carcinoma
Hist Subtype1: ductal_carcinoma
Notes:
Source: ATCC
Expression arrays: CASED_p_NCLE_RNA4_HG-U133_Plus_2_E02_383668
SNP arrays: FIEFS_p_NCLE_DNA_Affy5_GenomeWideSNP_6_B11_410900
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in HCC1143

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 HCC1143_BREAST 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM28 8 24211994 24211997 HCC1143_BREAST 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AIFM3 p.Y527C 22 21333919 21333919 HCC1143_BREAST 37 Missense_Mutation SNP A G uc002ztj.2 AIFM3_uc002ztk.... Hybrid_Cap... view
AIM1 p.C1240F 6 106991376 106991376 HCC1143_BREAST 37 Missense_Mutation SNP G T uc003prh.2 AIM1_uc003pri.2... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 HCC1143_BREAST 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ANAPC5 p.Q617H 12 121756122 121756122 HCC1143_BREAST 37 Missense_Mutation SNP C A uc001uag.2 ANAPC5_uc010szu... Hybrid_Cap... view
ATRX p.P667L X 76938748 76938748 HCC1143_BREAST 37 Missense_Mutation SNP G A rs61752457 uc004ecp.3 ATRX_uc004ecq.3... Hybrid_Cap... view
BRD2 6 32948599 32948599 HCC1143_BREAST 37 3'UTR Del C - uc010juh.2 BRD2_uc003ocn.3... Hybrid_Cap...
CACNB2 10 18828721 18828722 HCC1143_BREAST 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CATSPERB p.Q1081* 14 92047343 92047343 HCC1143_BREAST 37 Nonsense_Mutation SNP G A uc001xzs.1 CATSPERB_uc010a... Hybrid_Cap... view
CD40 20 44751957 44751957 HCC1143_BREAST 37 Intron SNP A C uc002xrg.1 CD40_uc002xrf.1... Hybrid_Cap... view
CDK11B 1 1654066 1654068 HCC1143_BREAST 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CEP110 p.A357T 9 123874803 123874803 HCC1143_BREAST 37 Missense_Mutation SNP G A uc004bkx.1 CEP110_uc004bkw... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 HCC1143_BREAST 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 HCC1143_BREAST 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 HCC1143_BREAST 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CNTN6 p.S585C 3 1414606 1414606 HCC1143_BREAST 37 Missense_Mutation SNP A T uc003boz.2 CNTN6_uc011asj.... Hybrid_Cap... view
CREB3L2 p.T100del 7 137612914 137612916 HCC1143_BREAST 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSPP1 p.E1114A 8 68102915 68102915 HCC1143_BREAST 37 Missense_Mutation SNP A C uc003xxi.2 ARFGEF1_uc003xx... Hybrid_Cap... view
CTBP2 p.K974fs 10 126678123 126678123 HCC1143_BREAST 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
CUBN p.I2208M 10 16967262 16967262 HCC1143_BREAST 37 Missense_Mutation SNP G C uc001ioo.2 Hybrid_Cap... view
DACH1 13 72014625 72014626 HCC1143_BREAST 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DST p.S3380C 6 56417095 56417095 HCC1143_BREAST 37 Missense_Mutation SNP T A uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
EDN1 6 12290729 12290729 HCC1143_BREAST 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EIF2B5 3 183853075 183853075 HCC1143_BREAST 37 5'UTR SNP G A uc003fmp.2 EIF2B5_uc010hxs... Hybrid_Cap... view
ETV1 7 14028708 14028708 HCC1143_BREAST 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FANCD2 3 10143086 10143087 HCC1143_BREAST 37 3'UTR Ins - A uc003bux.1 FANCD2_uc003buy... Hybrid_Cap...
FBLN5 p.A223G 14 92357639 92357639 HCC1143_BREAST 37 Missense_Mutation SNP G C uc010aue.2 FBLN5_uc010aud.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 HCC1143_BREAST 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR2 p.R203C 10 123310821 123310821 HCC1143_BREAST 37 Missense_Mutation SNP G A uc010qtj.1 FGFR2_uc010qtg.... Hybrid_Cap... view
FLI1 11 128638217 128638217 HCC1143_BREAST 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 HCC1143_BREAST 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FZD1 p.93_94insP 7 90894459 90894460 HCC1143_BREAST 37 In_Frame_Ins Ins - CCG uc003ula.2 Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 HCC1143_BREAST 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 HCC1143_BREAST 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIN2A p.H405D 16 9943728 9943728 HCC1143_BREAST 37 Missense_Mutation SNP G C uc002czo.3 GRIN2A_uc010uym... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 HCC1143_BREAST 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HDAC4 p.S1025_splice 2 239976444 239976444 HCC1143_BREAST 37 Splice_Site_SNP SNP C T uc002vyk.3 HDAC4_uc010fyy.... Hybrid_Cap... view
HEPH X 65476294 65476294 HCC1143_BREAST 37 Intron SNP T G uc011moz.1 HEPH_uc004dwn.2... Hybrid_Cap... view
HSP90B1 p.E791del 12 104341188 104341190 HCC1143_BREAST 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 HCC1143_BREAST 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 HCC1143_BREAST 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KIAA0802 p.C1309Y 18 8825434 8825434 HCC1143_BREAST 37 Missense_Mutation SNP G A uc002knr.2 KIAA0802_uc002k... Hybrid_Cap... view
KLK7 19 51480672 51480675 HCC1143_BREAST 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LPP p.R415H 3 188477904 188477904 HCC1143_BREAST 37 Missense_Mutation SNP G A uc003frs.1 LPP_uc011bsg.1_... Hybrid_Cap... view
MAF 16 79628537 79628537 HCC1143_BREAST 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 HCC1143_BREAST 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K1 15 66679649 66679650 HCC1143_BREAST 37 5'UTR Ins - C rs67229745 uc010bhq.2 Hybrid_Cap...
MAP2K6 17 67538038 67538038 HCC1143_BREAST 37 3'UTR SNP T C uc002jij.2 Hybrid_Cap... view
MAP3K14 p.R218_splice 17 43364293 43364294 HCC1143_BREAST 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K4 6 161538049 161538049 HCC1143_BREAST 37 3'UTR SNP G C uc003qtn.2 MAP3K4_uc003qto... Hybrid_Cap... view
MAPKAPK3 3 50685575 50685575 HCC1143_BREAST 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MCM3APAS 21 47671275 47671276 HCC1143_BREAST 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MEF2A p.V381F 15 100250964 100250964 HCC1143_BREAST 37 Missense_Mutation SNP G T uc010urw.1 MEF2A_uc010urv.... Hybrid_Cap... view
MLL3 p.Y816fs 7 151945071 151945072 HCC1143_BREAST 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
MMP1 p.G434_splice 11 102661433 102661433 HCC1143_BREAST 37 Splice_Site_SNP SNP C A rs61753766 uc001phi.2 MMP1_uc010ruv.1... Hybrid_Cap... view
MYH1 p.G532V 17 10411982 10411982 HCC1143_BREAST 37 Missense_Mutation SNP C A uc002gmo.2 Hybrid_Cap... view
MYST2 17 47892946 47892946 HCC1143_BREAST 37 Intron SNP G T uc002ipm.2 MYST2_uc002ipl.... Hybrid_Cap... view
NCAM1 11 112832276 112832277 HCC1143_BREAST 37 5'UTR Ins - G uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832307 112832308 HCC1143_BREAST 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 HCC1143_BREAST 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279837 46279839 HCC1143_BREAST 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NCOA3 20 46282339 46282340 HCC1143_BREAST 37 3'UTR Ins - AT uc002xtk.2 NCOA3_uc002xtl.... Hybrid_Cap...
NLRP1 p.R890K 17 5445207 5445207 HCC1143_BREAST 37 Missense_Mutation SNP C T uc002gci.2 NLRP1_uc002gcg.... Hybrid_Cap... view
NOTCH2 1 120478007 120478007 HCC1143_BREAST 37 Intron SNP A T uc001eik.2 NOTCH2_uc001eil... Hybrid_Cap... view
NPR1 1 153665919 153665920 HCC1143_BREAST 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 HCC1143_BREAST 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 HCC1143_BREAST 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP214 9 134067556 134067557 HCC1143_BREAST 37 Intron Ins - T rs66652901 uc004cag.2 NUP214_uc004cah... Hybrid_Cap...
NUP98 p.S84* 11 3800207 3800207 HCC1143_BREAST 37 Nonsense_Mutation SNP G C uc001lyh.2 NUP98_uc001lyi.... Hybrid_Cap... view
PCM1 p.E920D 8 17822182 17822182 HCC1143_BREAST 37 Missense_Mutation SNP A C rs34935098 uc003wyi.3 PCM1_uc011kyh.1... Hybrid_Cap... view
PDE4DIP p.V486fs 1 144917828 144917828 HCC1143_BREAST 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PGR 11 100933598 100933599 HCC1143_BREAST 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3R2 p.C657G 19 18279696 18279696 HCC1143_BREAST 37 Missense_Mutation SNP T G uc002nia.1 PIK3R2_uc002nib... Hybrid_Cap... view
PLAG1 p.R224* 8 57079635 57079635 HCC1143_BREAST 37 Nonsense_Mutation SNP G A uc003xsq.3 PLAG1_uc003xsr.... Hybrid_Cap... view
PML p.E633K 15 74336597 74336597 HCC1143_BREAST 37 Missense_Mutation SNP G A uc002awv.2 PML_uc002awu.2_... Hybrid_Cap... view
PPP1R3A p.G554A 7 113519486 113519486 HCC1143_BREAST 37 Missense_Mutation SNP C G uc010ljy.1 Hybrid_Cap... view
PRKAA1 p.Q16R 5 40798245 40798245 HCC1143_BREAST 37 Missense_Mutation SNP T C uc003jmb.2 PRKAA1_uc003jmc... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 HCC1143_BREAST 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG1 10 52751088 52751089 HCC1143_BREAST 37 5'UTR Ins - GCT rs67900156;rs71029335 uc001jjm.2 PRKG1_uc010qhp.... Hybrid_Cap...
PTPRC p.G863R 1 198711392 198711392 HCC1143_BREAST 37 Missense_Mutation SNP G A uc001gur.1 PTPRC_uc001gus.... Hybrid_Cap... view
RANBP17 p.K734N 5 170632587 170632587 HCC1143_BREAST 37 Missense_Mutation SNP G T uc003mba.2 RANBP17_uc003mb... Hybrid_Cap... view
RASGRF1 15 79277150 79277151 HCC1143_BREAST 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 HCC1143_BREAST 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
SMAD2 18 45368007 45368007 HCC1143_BREAST 37 3'UTR SNP G A rs117127867 uc002lcy.2 SMAD2_uc002lcz.... Hybrid_Cap... view
SMARCA4 p.R1323H 19 11145606 11145606 HCC1143_BREAST 37 Missense_Mutation SNP G A rs61750054 uc010dxo.2 SMARCA4_uc002mq... Hybrid_Cap... view
SMC2 p.D408N 9 106874063 106874063 HCC1143_BREAST 37 Missense_Mutation SNP G A uc004bbv.2 SMC2_uc004bbu.1... Hybrid_Cap... view
STK31 7 23872024 23872025 HCC1143_BREAST 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TET1 p.V873I 10 70405103 70405103 HCC1143_BREAST 37 Missense_Mutation SNP G A uc001jok.3 Hybrid_Cap... view
TGFB2 1 218519928 218519929 HCC1143_BREAST 37 5'UTR Ins - AAAC uc001hln.2 TGFB2_uc001hll.... Hybrid_Cap...
TIAM1 p.R1536Q 21 32492855 32492855 HCC1143_BREAST 37 Missense_Mutation SNP C T uc002yow.1 TIAM1_uc011adk.... Hybrid_Cap... view
TLE1 9 84202837 84202838 HCC1143_BREAST 37 Intron Ins - TGTCATCCCGCC rs5898748 uc004alz.2 TLE1_uc004aly.2... Hybrid_Cap...
TMEM123 11 102269398 102269398 HCC1143_BREAST 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TMEM123 11 102269461 102269461 HCC1143_BREAST 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.R248Q 17 7577538 7577538 HCC1143_BREAST 37 Missense_Mutation SNP C T rs11540652 uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 HCC1143_BREAST 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRPS1 8 116635872 116635873 HCC1143_BREAST 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TSHR 14 81574828 81574829 HCC1143_BREAST 37 Intron Ins - T rs117209823 uc001xvd.1 TSHR_uc001xvb.1... Hybrid_Cap...
TTBK1 p.E771del 6 43250726 43250728 HCC1143_BREAST 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
UNC13C p.R1650W 15 54786820 54786820 HCC1143_BREAST 37 Missense_Mutation SNP C T uc002ack.2 Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 HCC1143_BREAST 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WBP4 p.K113R 13 41642772 41642772 HCC1143_BREAST 37 Missense_Mutation SNP A G uc001uxt.2 WBP4_uc010tfd.1... Hybrid_Cap... view
ZNF423 p.E793G 16 49670685 49670685 HCC1143_BREAST 37 Missense_Mutation SNP T C uc002efs.2 ZNF423_uc010vgn... Hybrid_Cap... view