Annotation Summary for Cell Line: HCC1187  

Cell line primary name: HCC1187
Cell line aliases:
Gender: F
Site Primary: breast
Histology: carcinoma
Hist Subtype1: ductal_carcinoma
Notes:
Source: ATCC
Expression arrays: CASED_p_NCLE_RNA4_HG-U133_Plus_2_G09_383594
SNP arrays: LOBBY_p_NCLE_DNAAffy6_GenomeWideSNP_6_B11_437316
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in HCC1187

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 HCC1187_BREAST 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACACA 17 35766564 35766564 HCC1187_BREAST 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM17 2 9630245 9630245 HCC1187_BREAST 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 HCC1187_BREAST 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS20 p.Y1176C 12 43822565 43822565 HCC1187_BREAST 37 Missense_Mutation SNP T C uc010skx.1 ADAMTS20_uc001r... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 HCC1187_BREAST 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 HCC1187_BREAST 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.1388_1389FF>F 18 56203253 56203255 HCC1187_BREAST 37 In_Frame_Del Del AAG - uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
BAP1 p.Q261* 3 52440271 52440271 HCC1187_BREAST 37 Nonsense_Mutation SNP G A uc003ddx.2 BAP1_uc003ddw.2... Hybrid_Cap... view
BCR 22 23631813 23631814 HCC1187_BREAST 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BCR 22 23632777 23632778 HCC1187_BREAST 37 Intron Ins - T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BTK p.D583A X 100608962 100608962 HCC1187_BREAST 37 Missense_Mutation SNP T G uc010nno.2 BTK_uc004ehf.2_... Hybrid_Cap... view
CABC1 1 227171585 227171585 HCC1187_BREAST 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CABC1 1 227171736 227171737 HCC1187_BREAST 37 Intron Ins - T rs1574184 uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 HCC1187_BREAST 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CLTCL1 22 19196673 19196674 HCC1187_BREAST 37 Intron Ins - A uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 HCC1187_BREAST 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CXCL12 10 44873992 44873993 HCC1187_BREAST 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
CYB5R4 p.D371Y 6 84649777 84649777 HCC1187_BREAST 37 Missense_Mutation SNP G T uc003pkf.2 Hybrid_Cap... view
DDR2 1 162750211 162750212 HCC1187_BREAST 37 3'UTR Del TT - uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap...
DIP2C p.V1264M 10 373080 373080 HCC1187_BREAST 37 Missense_Mutation SNP C T uc001ifp.2 Hybrid_Cap... view
DYRK1A 21 38884966 38884967 HCC1187_BREAST 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EDN1 6 12290729 12290729 HCC1187_BREAST 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EPHA6 3 97467610 97467611 HCC1187_BREAST 37 3'UTR Ins - CT uc010how.1 Hybrid_Cap...
EPHA8 1 22928305 22928305 HCC1187_BREAST 37 3'UTR SNP G T uc001bfx.1 Hybrid_Cap... view
EPHB6 7 142568771 142568771 HCC1187_BREAST 37 3'UTR Del C - uc011kst.1 EPHB6_uc011ksu.... Hybrid_Cap...
ETV1 7 14028708 14028708 HCC1187_BREAST 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 HCC1187_BREAST 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 HCC1187_BREAST 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 HCC1187_BREAST 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 HCC1187_BREAST 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 HCC1187_BREAST 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRAMD1B 11 123396824 123396824 HCC1187_BREAST 37 5'UTR SNP G C uc001pyw.2 GRAMD1B_uc001py... Hybrid_Cap... view
GRIA3 X 122318386 122318387 HCC1187_BREAST 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 HCC1187_BREAST 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HNF1A 12 121434630 121434631 HCC1187_BREAST 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 HCC1187_BREAST 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITIH5L p.P76L X 54823405 54823405 HCC1187_BREAST 37 Missense_Mutation SNP G A uc004dtj.2 Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 HCC1187_BREAST 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 HCC1187_BREAST 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPKAPK3 3 50685575 50685575 HCC1187_BREAST 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MCL1 1 150549776 150549776 HCC1187_BREAST 37 3'UTR SNP G C uc001euz.2 MCL1_uc010pch.1... Hybrid_Cap... view
MLL3 p.Y816fs 7 151945071 151945072 HCC1187_BREAST 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
MSH3 p.PPA66del 5 79950742 79950750 HCC1187_BREAST 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MYH9 p.H1401del 22 36688174 36688176 HCC1187_BREAST 37 In_Frame_Del Del TGC - rs116972183 uc003apg.2 Hybrid_Cap...
NCAM1 11 112832307 112832308 HCC1187_BREAST 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 HCC1187_BREAST 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 HCC1187_BREAST 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 HCC1187_BREAST 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NFKBIA p.R143fs 14 35872475 35872476 HCC1187_BREAST 37 Frame_Shift_Ins Ins - G uc001wtf.3 NFKBIA_uc001wte... Hybrid_Cap...
NOS2 p.A679S 17 26094863 26094863 HCC1187_BREAST 37 Missense_Mutation SNP C A uc002gzu.2 NOS2_uc010wab.1... Hybrid_Cap... view
NOV 8 120435425 120435425 HCC1187_BREAST 37 3'UTR SNP A G uc003yoq.2 Hybrid_Cap... view
NPR1 1 153665919 153665920 HCC1187_BREAST 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 HCC1187_BREAST 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR3C1 5 142780419 142780419 HCC1187_BREAST 37 Splice_Site_SNP SNP T A uc003lmy.2 NR3C1_uc003lmz.... Hybrid_Cap... view
NUP98 p.G1652V 11 3700902 3700902 HCC1187_BREAST 37 Missense_Mutation SNP C A uc001lyh.2 NUP98_uc001lyi.... Hybrid_Cap... view
PAX3 2 223158653 223158653 HCC1187_BREAST 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAXIP1 p.F491C 7 154760439 154760439 HCC1187_BREAST 37 Missense_Mutation SNP A C uc003wlp.2 PAXIP1_uc003wlq... Hybrid_Cap... view
PCDH15 p.I48T 10 56287601 56287601 HCC1187_BREAST 37 Missense_Mutation SNP A G uc010qhy.1 PCDH15_uc010qhq... Hybrid_Cap... view
PDGFRA 4 55130162 55130162 HCC1187_BREAST 37 Intron Del T - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PDK4 7 95221928 95221928 HCC1187_BREAST 37 Intron Del A - uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap...
PMS1 2 190670539 190670540 HCC1187_BREAST 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PPP3R1 p.F15_splice 2 68415824 68415824 HCC1187_BREAST 37 Splice_Site_SNP SNP T A uc002sei.1 Hybrid_Cap... view
PRAME 22 22899323 22899323 HCC1187_BREAST 37 De_novo_Start_OutOfFrame SNP C T uc002zwf.2 LOC96610_uc011a... Hybrid_Cap... view
PRKAA2 p.P371T 1 57169966 57169966 HCC1187_BREAST 37 Missense_Mutation SNP C A uc001cyk.3 Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 HCC1187_BREAST 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTCH2 p.I533T 1 45294079 45294079 HCC1187_BREAST 37 Missense_Mutation SNP A G rs61751010 uc010olf.1 PTCH2_uc010olg.... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 HCC1187_BREAST 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
SMG1 p.K3583Q 16 18823324 18823324 HCC1187_BREAST 37 Missense_Mutation SNP T G uc002dfm.2 SMG1_uc010bwb.2... Hybrid_Cap... view
SPEN p.R1488I 1 16257198 16257198 HCC1187_BREAST 37 Missense_Mutation SNP G T uc001axk.1 SPEN_uc010obp.1... Hybrid_Cap... view
SSX1 p.L61Q X 48117293 48117293 HCC1187_BREAST 37 Missense_Mutation SNP T A uc004djb.1 Hybrid_Cap... view
STK17B 2 197002129 197002129 HCC1187_BREAST 37 3'UTR SNP T C uc002utk.2 STK17B_uc010fsh... Hybrid_Cap... view
STK31 7 23872024 23872025 HCC1187_BREAST 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TEC 4 48139307 48139310 HCC1187_BREAST 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TGFB2 1 218519928 218519929 HCC1187_BREAST 37 5'UTR Ins - AAAC uc001hln.2 TGFB2_uc001hll.... Hybrid_Cap...
TLK1 2 171850178 171850179 HCC1187_BREAST 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TMEM123 11 102269398 102269398 HCC1187_BREAST 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNFRSF1A 12 6450988 6450988 HCC1187_BREAST 37 5'UTR SNP A C uc001qnu.2 TNFRSF1A_uc010s... Hybrid_Cap... view
TPR p.V331G 1 186330004 186330004 HCC1187_BREAST 37 Missense_Mutation SNP A C uc001grv.2 TPR_uc010pop.1_... Hybrid_Cap... view
TRIM33 1 114940211 114940212 HCC1187_BREAST 37 3'UTR Ins - T rs66490349 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRPS1 8 116635872 116635873 HCC1187_BREAST 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TSC2 16 2138671 2138672 HCC1187_BREAST 37 3'UTR Del AA - uc002con.2 TSC2_uc010bsd.2... Hybrid_Cap...
TTN p.9928_9928E>EE 2 179544685 179544686 HCC1187_BREAST 37 In_Frame_Ins Ins - TCT uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN 2 179616749 179616749 HCC1187_BREAST 37 Intron SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
ZNF423 p.A104T 16 49672753 49672753 HCC1187_BREAST 37 Missense_Mutation SNP C T uc002efs.2 ZNF423_uc010vgn... Hybrid_Cap... view
ZNF608 p.R1326Q 5 123980083 123980083 HCC1187_BREAST 37 Missense_Mutation SNP C T rs61749625 uc003ktq.1 ZNF608_uc003ktr... Hybrid_Cap... view