Annotation Summary for Cell Line: HCC1395  

Cell line primary name: HCC1395
Cell line aliases:
Gender: F
Site Primary: breast
Histology: carcinoma
Hist Subtype1: ductal_carcinoma
Notes:
Source: ATCC
Expression arrays: CASED_p_NCLE_RNA4_HG-U133_Plus_2_E12_383706
SNP arrays: FASTS_p_NCLE_DNAAffy4_S_GenomeWideSNP_6_H12_335378
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in HCC1395

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABL2 p.T753A 1 179078145 179078145 HCC1395_BREAST 37 Missense_Mutation SNP T C uc001gmj.3 ABL2_uc010pnf.1... Hybrid_Cap... view
ADAM17 2 9630245 9630245 HCC1395_BREAST 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 HCC1395_BREAST 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTSL3 p.I1645F 15 84705703 84705703 HCC1395_BREAST 37 Missense_Mutation SNP A T uc002bjz.3 ADAMTSL3_uc010b... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 HCC1395_BREAST 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP6 p.K910M 14 33069997 33069997 HCC1395_BREAST 37 Missense_Mutation SNP A T uc001wrq.2 AKAP6_uc010aml.... Hybrid_Cap... view
AKAP6 p.M1192I 14 33243087 33243087 HCC1395_BREAST 37 Missense_Mutation SNP G T uc001wrq.2 Hybrid_Cap... view
AKAP9 p.D2313H 7 91707181 91707181 HCC1395_BREAST 37 Missense_Mutation SNP G C uc003ulg.2 AKAP9_uc003ulf.... Hybrid_Cap... view
ALPK2 p.EDTST1006del 18 56204388 56204402 HCC1395_BREAST 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ATF2 p.D352H 2 175957920 175957920 HCC1395_BREAST 37 Missense_Mutation SNP C G uc002ujl.2 ATF2_uc010fqv.2... Hybrid_Cap... view
ATRX p.K1175E X 76937225 76937225 HCC1395_BREAST 37 Missense_Mutation SNP T C uc004ecp.3 ATRX_uc004ecq.3... Hybrid_Cap... view
BAI3 6 70049492 70049492 HCC1395_BREAST 37 Intron SNP A T uc003pev.3 BAI3_uc010kak.2... Hybrid_Cap... view
BCR 22 23631813 23631814 HCC1395_BREAST 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BCR 22 23632777 23632778 HCC1395_BREAST 37 Intron Ins - T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BMP4 14 54416601 54416602 HCC1395_BREAST 37 3'UTR Ins - AT rs74495140;rs76335800 uc001xal.3 BMP4_uc010aoh.2... Hybrid_Cap...
BRCA1 p.R1772* 17 41209095 41209095 HCC1395_BREAST 37 Nonsense_Mutation SNP G A rs80357123 uc002ict.2 BRCA1_uc010whp.... Hybrid_Cap... view
BRCA2 p.E1593* 13 32913269 32913269 HCC1395_BREAST 37 Nonsense_Mutation SNP G T uc001uub.1 Hybrid_Cap... view
C9ORF96 9 136270592 136270592 HCC1395_BREAST 37 3'UTR SNP G C uc004cdk.2 C9orf96_uc004cd... Hybrid_Cap... view
CABC1 1 227171585 227171585 HCC1395_BREAST 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CACNB2 10 18828721 18828722 HCC1395_BREAST 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CARD14 17 78182309 78182312 HCC1395_BREAST 37 3'UTR Del CACA - uc002jxw.1 CARD14_uc002jxt... Hybrid_Cap...
CD160 1 145696380 145696380 HCC1395_BREAST 37 3'UTR SNP A G uc001eol.1 NBPF10_uc001emp... Hybrid_Cap... view
CDK11B 1 1654066 1654068 HCC1395_BREAST 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CHD1 p.P1684del 5 98192165 98192167 HCC1395_BREAST 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CLPTM1L p.K313N 5 1331951 1331951 HCC1395_BREAST 37 Missense_Mutation SNP C A uc003jch.2 CLPTM1L_uc003jc... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 HCC1395_BREAST 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 HCC1395_BREAST 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 HCC1395_BREAST 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CREBBP p.H1297Q 16 3795301 3795301 HCC1395_BREAST 37 Missense_Mutation SNP G C uc002cvv.2 CREBBP_uc002cvw... Hybrid_Cap... view
CSF1R p.Y61Y 5 149460454 149460454 HCC1395_BREAST 37 Silent SNP G A uc003lrl.2 CSF1R_uc011dcd.... Hybrid_Cap... view
CSNK2A1 20 464565 464565 HCC1395_BREAST 37 3'UTR SNP C T uc002wdw.1 CSNK2A1_uc002wd... Hybrid_Cap... view
DBN1 p.E280K 5 176887556 176887556 HCC1395_BREAST 37 Missense_Mutation SNP C T uc003mgx.2 DBN1_uc011dga.1... Hybrid_Cap... view
DGKG p.E706K 3 185882787 185882787 HCC1395_BREAST 37 Missense_Mutation SNP C T uc003fqa.2 DGKG_uc003fqb.2... Hybrid_Cap... view
DVL1 p.S610L 1 1271706 1271706 HCC1395_BREAST 37 Missense_Mutation SNP G A uc001aer.3 DVL1_uc002quu.2... Hybrid_Cap... view
EDN1 6 12290729 12290729 HCC1395_BREAST 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EPHA10 p.L709M 1 38187353 38187353 HCC1395_BREAST 37 Missense_Mutation SNP G T uc009vvi.2 EPHA10_uc001cbt... Hybrid_Cap... view
EPHA6 3 97367230 97367231 HCC1395_BREAST 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHA8 p.N123K 1 22902919 22902919 HCC1395_BREAST 37 Missense_Mutation SNP C A uc001bfx.1 EPHA8_uc001bfw.... Hybrid_Cap... view
EPS15 1 51822219 51822220 HCC1395_BREAST 37 3'UTR Ins - A rs111272942 uc001csq.1 EPS15_uc009vyz.... Hybrid_Cap...
ETV1 7 14028708 14028708 HCC1395_BREAST 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR1 p.S125L 8 38285938 38285938 HCC1395_BREAST 37 Missense_Mutation SNP G A uc003xlp.2 FGFR1_uc011lbo.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 HCC1395_BREAST 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 HCC1395_BREAST 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FIGF p.E177K X 15373384 15373384 HCC1395_BREAST 37 Missense_Mutation SNP C T uc004cwt.1 Hybrid_Cap... view
FLI1 11 128638217 128638217 HCC1395_BREAST 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FZD1 p.93_94insP 7 90894459 90894460 HCC1395_BREAST 37 In_Frame_Ins Ins - CCG uc003ula.2 Hybrid_Cap...
GLI2 p.K485R 2 121736095 121736095 HCC1395_BREAST 37 Missense_Mutation SNP A G uc010flp.2 GLI2_uc002tmq.1... Hybrid_Cap... view
GRIA3 X 122318386 122318387 HCC1395_BREAST 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
HNF1A 12 121434630 121434631 HCC1395_BREAST 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSPA4 p.L751P 5 132439651 132439651 HCC1395_BREAST 37 Missense_Mutation SNP T C uc003kyj.2 Hybrid_Cap... view
IKBKE p.L70L 1 206647796 206647796 HCC1395_BREAST 37 Silent SNP C G rs56388356 uc001hdz.1 IKBKE_uc009xbu.... Hybrid_Cap... view
IL1R2 p.T143I 2 102632428 102632428 HCC1395_BREAST 37 Missense_Mutation SNP C T uc002tbm.2 IL1R2_uc002tbn.... Hybrid_Cap... view
ILK 11 6630029 6630029 HCC1395_BREAST 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGB6 p.I729F 2 160964273 160964273 HCC1395_BREAST 37 Missense_Mutation SNP T A uc002ubh.2 ITGB6_uc010fou.... Hybrid_Cap... view
KLK7 19 51480672 51480675 HCC1395_BREAST 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LETM2 8 38265796 38265798 HCC1395_BREAST 37 3'UTR Del ACT - uc003xlm.1 LETM2_uc003xll.... Hybrid_Cap...
LRP2 p.G774* 2 170127414 170127414 HCC1395_BREAST 37 Nonsense_Mutation SNP C A uc002ues.2 LRP2_uc010zdf.1... Hybrid_Cap... view
MAK p.R272P 6 10802141 10802141 HCC1395_BREAST 37 Missense_Mutation SNP C G uc003mzl.2 SYCP2L_uc011dim... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 HCC1395_BREAST 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 HCC1395_BREAST 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 HCC1395_BREAST 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K6 p.I772L 1 27686354 27686354 HCC1395_BREAST 37 Missense_Mutation SNP T G uc001bny.1 MAP3K6_uc009vsw... Hybrid_Cap... view
MAPKBP1 15 42111753 42111754 HCC1395_BREAST 37 Intron Ins - C rs3034891 uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap...
MLLT6 17 36882064 36882064 HCC1395_BREAST 37 3'UTR SNP T C uc002hqi.3 MLLT6_uc002hqk.... Hybrid_Cap... view
MTMR11 1 149900985 149900986 HCC1395_BREAST 37 3'UTR Ins - A rs114426061 uc001etl.3 SF3B4_uc001etj.... Hybrid_Cap...
MYH1 p.S1306L 17 10402358 10402358 HCC1395_BREAST 37 Missense_Mutation SNP G A uc002gmo.2 Hybrid_Cap... view
NCAM1 11 112832307 112832308 HCC1395_BREAST 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 HCC1395_BREAST 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279864 46279866 HCC1395_BREAST 37 In_Frame_Del Del CAA - rs1132443;rs28529067 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK10 3 27203820 27203820 HCC1395_BREAST 37 3'UTR SNP C T uc003cds.1 NEK10_uc010hfj.... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 HCC1395_BREAST 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 HCC1395_BREAST 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NGFR p.P426L 17 47590364 47590364 HCC1395_BREAST 37 Missense_Mutation SNP C T uc002ioz.3 Hybrid_Cap... view
NOVA1 14 26917034 26917034 HCC1395_BREAST 37 3'UTR SNP A T uc001wpy.2 NOVA1_uc001wpz.... Hybrid_Cap... view
NOVA1 p.T182R 14 26918144 26918144 HCC1395_BREAST 37 Missense_Mutation SNP G C uc001wpy.2 NOVA1_uc001wpz.... Hybrid_Cap... view
NPR1 1 153665919 153665920 HCC1395_BREAST 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 HCC1395_BREAST 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP214 9 134067556 134067557 HCC1395_BREAST 37 Intron Ins - T rs66652901 uc004cag.2 NUP214_uc004cah... Hybrid_Cap...
PCDH15 10 55581525 55581525 HCC1395_BREAST 37 3'UTR SNP A G uc010qhy.1 PCDH15_uc010qhq... Hybrid_Cap... view
PCM1 8 17813218 17813218 HCC1395_BREAST 37 Intron Del T - uc003wyi.3 PCM1_uc011kyh.1... Hybrid_Cap...
PDGFRB p.T882I 5 149499628 149499628 HCC1395_BREAST 37 Missense_Mutation SNP G A uc003lro.2 PDGFRB_uc010jhd... Hybrid_Cap... view
PER1 p.S842L 17 8047131 8047131 HCC1395_BREAST 37 Missense_Mutation SNP G A uc002gkd.2 PER1_uc010cns.2... Hybrid_Cap... view
PLCG1 p.S582C 20 39794412 39794412 HCC1395_BREAST 37 Missense_Mutation SNP C G uc002xjo.1 PLCG1_uc002xjp.... Hybrid_Cap... view
PRKD3 2 37480319 37480320 HCC1395_BREAST 37 Stop_Codon_Ins Ins - T rs79875666 uc002rqd.2 Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 HCC1395_BREAST 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RGL1 p.Y209S 1 183849845 183849845 HCC1395_BREAST 37 Missense_Mutation SNP A C uc001gqm.2 RGL1_uc010pof.1... Hybrid_Cap... view
RPGRIP1 14 21792701 21792701 HCC1395_BREAST 37 Intron SNP C G uc001wag.2 RPGRIP1_uc001wa... Hybrid_Cap... view
SEMA5B p.I223M 3 122646818 122646818 HCC1395_BREAST 37 Missense_Mutation SNP G C uc003efz.1 SEMA5B_uc011bju... Hybrid_Cap... view
SGK3 p.A92V 8 67726109 67726109 HCC1395_BREAST 37 Missense_Mutation SNP C T uc003xwr.2 SGK3_uc003xwp.2... Hybrid_Cap... view
SLC29A1 6 44197798 44197798 HCC1395_BREAST 37 Intron SNP G A uc003oww.1 SLC29A1_uc011dv... Hybrid_Cap... view
SLK p.E1160D 10 105781410 105781410 HCC1395_BREAST 37 Missense_Mutation SNP G T uc001kxo.1 SLK_uc001kxp.1_... Hybrid_Cap... view
SORL1 11 121500400 121500401 HCC1395_BREAST 37 3'UTR Ins - A rs73020651 uc001pxx.2 SORL1_uc010rzp.... Hybrid_Cap...
SPEG p.Y1258C 2 220336647 220336647 HCC1395_BREAST 37 Missense_Mutation SNP A G uc010fwg.2 Hybrid_Cap... view
STAG3 7 99786403 99786403 HCC1395_BREAST 37 Intron SNP C T uc003utx.1 STAG3_uc010lgs.... Hybrid_Cap... view
STAG3 7 99811730 99811730 HCC1395_BREAST 37 3'UTR SNP T C uc003utx.1 STAG3_uc011kjk.... Hybrid_Cap... view
STAT1 p.P491A 2 191847220 191847220 HCC1395_BREAST 37 Missense_Mutation SNP G C uc002usj.2 STAT1_uc010fse.... Hybrid_Cap... view
SUFU p.A22fs 10 104263973 104263974 HCC1395_BREAST 37 Frame_Shift_Ins Ins - C uc001kvy.1 SUFU_uc001kvw.1... Hybrid_Cap...
TAF1 p.DI348del X 70598132 70598137 HCC1395_BREAST 37 In_Frame_Del Del AGATA... - uc004dzt.3 BCYRN1_uc011mpt... Hybrid_Cap...
TESK1 p.H539Y 9 35609473 35609473 HCC1395_BREAST 37 Missense_Mutation SNP C T uc003zxa.2 TESK1_uc003zwz.... Hybrid_Cap... view
TG p.P1755R 8 133961051 133961051 HCC1395_BREAST 37 Missense_Mutation SNP C G uc003ytw.2 TG_uc010mdw.2_M... Hybrid_Cap... view
TLK1 2 171850178 171850179 HCC1395_BREAST 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TNIK p.R477S 3 170856159 170856159 HCC1395_BREAST 37 Missense_Mutation SNP G T uc003fhh.2 TNIK_uc003fhi.2... Hybrid_Cap... view
TP53 p.R175H 17 7578406 7578406 HCC1395_BREAST 37 Missense_Mutation SNP C T rs28934578 uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP53BP1 p.454_456PIP>P 15 43762078 43762083 HCC1395_BREAST 37 In_Frame_Del Del GGGAT... - uc001zrr.3 TP53BP1_uc010ud... Hybrid_Cap...
TPM4 p.E240Q 19 16204509 16204509 HCC1395_BREAST 37 Missense_Mutation SNP G C uc002ndi.2 TPM4_uc002ndj.2... Hybrid_Cap... view
TRIB1 p.S340F 8 126448613 126448614 HCC1395_BREAST 37 Missense_Mutation DNP CC TT uc003yrx.2 TRIB1_uc011lis.... Hybrid_Cap...
TRIM33 1 114940215 114940216 HCC1395_BREAST 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRIM36 p.A607fs 5 114466295 114466301 HCC1395_BREAST 37 Frame_Shift_Del Del CTAAC... - uc003kqs.2 TRIM36_uc011cwc... Hybrid_Cap...
TRPM7 p.K153T 15 50935614 50935614 HCC1395_BREAST 37 Missense_Mutation SNP T G uc001zyt.3 TRPM7_uc010bew.... Hybrid_Cap... view
TRPS1 8 116635872 116635873 HCC1395_BREAST 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTBK1 p.E771del 6 43250726 43250728 HCC1395_BREAST 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
TTN 2 179391639 179391640 HCC1395_BREAST 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 HCC1395_BREAST 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
VPS13B p.L1477F 8 100523463 100523463 HCC1395_BREAST 37 Missense_Mutation SNP A T rs61754112 uc003yiv.2 VPS13B_uc003yiw... Hybrid_Cap... view
WNK1 p.Q1799E 12 998336 998336 HCC1395_BREAST 37 Missense_Mutation SNP C G uc001qio.3 WNK1_uc001qip.3... Hybrid_Cap... view