Annotation Summary for Cell Line: HCC2157  

Cell line primary name: HCC2157
Cell line aliases:
Gender: F
Site Primary: breast
Histology: carcinoma
Hist Subtype1: ductal_carcinoma
Notes:
Source: ATCC
Expression arrays: AGENT_p_NCLE_RNA6_HG-U133_Plus_2_B01_436616
SNP arrays: BOWER_p_NCLE_DNAAffy8_GenomeWideSNP_6_A07_464618
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in HCC2157

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABL1 p.R13K 9 133589744 133589744 HCC2157_BREAST 37 Missense_Mutation SNP G A uc004bzv.2 Hybrid_Cap... view
ADAM17 2 9630245 9630245 HCC2157_BREAST 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 HCC2157_BREAST 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAM32 8 38965211 38965211 HCC2157_BREAST 37 5'UTR SNP G A uc003xmt.3 ADAM32_uc011lch... Hybrid_Cap... view
ADHFE1 8 67380587 67380588 HCC2157_BREAST 37 Stop_Codon_Ins Ins - T uc003xwb.3 ADHFE1_uc003xwd... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 HCC2157_BREAST 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 HCC2157_BREAST 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK1 4 113347609 113347610 HCC2157_BREAST 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALS2 p.K245del 2 202625982 202625984 HCC2157_BREAST 37 In_Frame_Del Del TTT - uc002uyo.2 ALS2_uc002uyp.3... Hybrid_Cap...
ARHGAP29 p.G561_splice 1 94654391 94654391 HCC2157_BREAST 37 Splice_Site_SNP SNP A G uc001dqj.3 ARHGAP29_uc009w... Hybrid_Cap... view
ARHGAP29 p.S552C 1 94654419 94654419 HCC2157_BREAST 37 Missense_Mutation SNP G C uc001dqj.3 ARHGAP29_uc009w... Hybrid_Cap... view
ASPH p.E172D 8 62559412 62559412 HCC2157_BREAST 37 Missense_Mutation SNP T G uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap... view
BCR 22 23631813 23631814 HCC2157_BREAST 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BMP4 14 54416601 54416602 HCC2157_BREAST 37 3'UTR Ins - A rs74495140;rs76335800 uc001xal.3 BMP4_uc010aoh.2... Hybrid_Cap...
CABC1 1 227171585 227171585 HCC2157_BREAST 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CACNA1F p.D314N X 49084787 49084787 HCC2157_BREAST 37 Missense_Mutation SNP C T uc004dnb.2 CACNA1F_uc010ni... Hybrid_Cap... view
CACNB2 10 18828721 18828722 HCC2157_BREAST 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDC7 p.N226S 1 91978719 91978719 HCC2157_BREAST 37 Missense_Mutation SNP A G rs35652063 uc001doe.2 CDC7_uc001dof.2... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 HCC2157_BREAST 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHD8 14 21853630 21853630 HCC2157_BREAST 37 3'UTR Del T - rs78520772 uc001was.1 CHD8_uc001war.1... Hybrid_Cap...
CHD8 p.R813H 14 21873400 21873400 HCC2157_BREAST 37 Missense_Mutation SNP C T uc001was.1 CHD8_uc001war.1... Hybrid_Cap... view
CHEK1 p.V312M 11 125513996 125513996 HCC2157_BREAST 37 Missense_Mutation SNP G A rs34097480 uc009zbo.2 CHEK1_uc010sbh.... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 HCC2157_BREAST 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CLTCL1 p.T103N 22 19241693 19241693 HCC2157_BREAST 37 Missense_Mutation SNP G T uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap... view
CNTN6 3 1339681 1339686 HCC2157_BREAST 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CUBN p.E2310fs 10 16960687 16960693 HCC2157_BREAST 37 Frame_Shift_Del Del TAACC... - uc001ioo.2 Hybrid_Cap...
CUBN p.R1003_splice 10 17107639 17107639 HCC2157_BREAST 37 Splice_Site_SNP SNP T G uc001ioo.2 Hybrid_Cap... view
DGKB p.E638K 7 14384943 14384943 HCC2157_BREAST 37 Missense_Mutation SNP C T uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap... view
EDN1 6 12296157 12296158 HCC2157_BREAST 37 Intron Ins - A rs75549802 uc003nae.3 EDN1_uc003nad.2... Hybrid_Cap...
EHBP1 p.R395T 2 63101561 63101561 HCC2157_BREAST 37 Missense_Mutation SNP G C uc002sby.2 EHBP1_uc010fcp.... Hybrid_Cap... view
EIF4A2 p.V182L 3 186503976 186503976 HCC2157_BREAST 37 Missense_Mutation SNP G C uc003fqu.2 EIF4A2_uc003fqs... Hybrid_Cap... view
EP300 22 41574970 41574972 HCC2157_BREAST 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA4 2 222290623 222290624 HCC2157_BREAST 37 3'UTR Ins - TT uc002vmq.2 EPHA4_uc002vmr.... Hybrid_Cap...
EPHA5 p.G724S 4 66230804 66230804 HCC2157_BREAST 37 Missense_Mutation SNP C T uc011cah.1 EPHA5_uc003hcx.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 HCC2157_BREAST 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHA8 p.R1003Q 1 22928224 22928224 HCC2157_BREAST 37 Missense_Mutation SNP G A uc001bfx.1 Hybrid_Cap... view
EPHB6 7 142568771 142568771 HCC2157_BREAST 37 3'UTR Del C - uc011kst.1 EPHB6_uc011ksu.... Hybrid_Cap...
ETV1 7 14028708 14028708 HCC2157_BREAST 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FBLN5 p.D161G 14 92403311 92403311 HCC2157_BREAST 37 Missense_Mutation SNP T C uc010aue.2 FBLN5_uc010aud.... Hybrid_Cap... view
FBN2 p.T2318S 5 127622469 127622469 HCC2157_BREAST 37 Missense_Mutation SNP G C uc003kuu.2 Hybrid_Cap... view
FGF20 8 16850433 16850433 HCC2157_BREAST 37 3'UTR SNP T C uc003wxc.1 FGF20_uc010lsv.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 HCC2157_BREAST 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FKBP1A 20 1352644 1352644 HCC2157_BREAST 37 Intron SNP G C uc002wey.2 FKBP1A_uc010gac... Hybrid_Cap... view
FLI1 11 128638217 128638217 HCC2157_BREAST 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNB p.A1565G 3 58120429 58120429 HCC2157_BREAST 37 Missense_Mutation SNP C G uc010hne.2 FLNB_uc003djj.2... Hybrid_Cap... view
FOXP1 3 71008341 71008342 HCC2157_BREAST 37 3'UTR Ins - T rs11433724;rs114233617 uc003dol.2 FOXP1_uc003dom.... Hybrid_Cap...
FSCB p.S775L 14 44973867 44973867 HCC2157_BREAST 37 Missense_Mutation SNP G A uc001wvn.2 Hybrid_Cap... view
GLI1 12 57857469 57857469 HCC2157_BREAST 37 5'UTR SNP G T uc001snx.2 GLI1_uc009zpp.2... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 HCC2157_BREAST 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 HCC2157_BREAST 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 HCC2157_BREAST 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
GUCY2F p.R10P X 108719137 108719137 HCC2157_BREAST 37 Missense_Mutation SNP C G uc004eod.3 GUCY2F_uc011msq... Hybrid_Cap... view
HDAC4 2 240011649 240011649 HCC2157_BREAST 37 Intron SNP C T uc002vyk.3 HDAC4_uc010fyz.... Hybrid_Cap... view
ILK 11 6630029 6630029 HCC2157_BREAST 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 HCC2157_BREAST 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KLK7 19 51480672 51480675 HCC2157_BREAST 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 HCC2157_BREAST 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 HCC2157_BREAST 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K13 3 185200341 185200341 HCC2157_BREAST 37 3'UTR SNP G C uc010hyf.2 MAP3K13_uc011br... Hybrid_Cap... view
MAP3K14 p.R218_splice 17 43364293 43364294 HCC2157_BREAST 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MN1 p.540_540Q>QQ 22 28194912 28194913 HCC2157_BREAST 37 In_Frame_Ins Ins - TGC rs45520238 uc003adj.2 Hybrid_Cap...
MSH3 p.AAA58del 5 79950709 79950717 HCC2157_BREAST 37 In_Frame_Del Del GCAGC... - rs67658031;rs2431220 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
NCAM1 11 112832307 112832308 HCC2157_BREAST 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 HCC2157_BREAST 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279864 46279866 HCC2157_BREAST 37 In_Frame_Del Del CAA - rs1132443;rs28529067 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NOS3 p.R543Q 7 150699034 150699034 HCC2157_BREAST 37 Missense_Mutation SNP G A uc003wif.2 NOS3_uc011kuy.1... Hybrid_Cap... view
NR1H2 p.176_177insQ 19 50881820 50881821 HCC2157_BREAST 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
OBSCN p.T1471M 1 228444454 228444454 HCC2157_BREAST 37 Missense_Mutation SNP C T uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
PARP9 p.T330M 3 122274134 122274134 HCC2157_BREAST 37 Missense_Mutation SNP G A rs72960494 uc010hri.2 PARP9_uc003eff.... Hybrid_Cap... view
PARP9 3 122278532 122278532 HCC2157_BREAST 37 5'UTR SNP A G rs72960498 uc010hri.2 PARP9_uc003eff.... Hybrid_Cap... view
PAX3 2 223066017 223066018 HCC2157_BREAST 37 Intron Ins - CC rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 HCC2157_BREAST 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX5 9 36840300 36840300 HCC2157_BREAST 37 3'UTR SNP A G uc003zzo.1 PAX5_uc011lpt.1... Hybrid_Cap... view
PAX5 9 37034095 37034095 HCC2157_BREAST 37 5'UTR Del C - uc003zzo.1 PAX5_uc011lpw.1... Hybrid_Cap...
PCDH15 10 55581545 55581545 HCC2157_BREAST 37 3'UTR SNP G A uc010qhy.1 PCDH15_uc010qhq... Hybrid_Cap... view
PDGFRA 4 55131002 55131003 HCC2157_BREAST 37 Intron Del AA - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PER1 p.N985S 17 8046702 8046702 HCC2157_BREAST 37 Missense_Mutation SNP T C uc002gkd.2 PER1_uc010cns.2... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 HCC2157_BREAST 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3R4 p.R936Q 3 130424530 130424530 HCC2157_BREAST 37 Missense_Mutation SNP C T uc003enj.2 Hybrid_Cap... view
PRKAA2 p.S523G 1 57173294 57173294 HCC2157_BREAST 37 Missense_Mutation SNP A G uc001cyk.3 Hybrid_Cap... view
PRKCA 17 64800201 64800201 HCC2157_BREAST 37 3'UTR SNP C T uc002jfp.1 Hybrid_Cap... view
PRKCD p.C415Y 3 53220340 53220340 HCC2157_BREAST 37 Missense_Mutation SNP G A rs35181307 uc003dgl.2 PRKCD_uc003dgm.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 HCC2157_BREAST 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RARG p.G430S 12 53605537 53605537 HCC2157_BREAST 37 Missense_Mutation SNP C T uc001sce.2 RARG_uc001scd.2... Hybrid_Cap... view
RBL1 20 35632029 35632029 HCC2157_BREAST 37 Intron Del A - uc002xgi.2 RBL1_uc010zvt.1... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 HCC2157_BREAST 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROBO1 3 78710018 78710018 HCC2157_BREAST 37 Intron SNP T A uc003dqe.2 ROBO1_uc003dqb.... Hybrid_Cap... view
SMURF2 17 62541834 62541835 HCC2157_BREAST 37 3'UTR Ins - A rs59188589 uc002jep.1 SMURF2_uc002jeq... Hybrid_Cap...
SORL1 p.K1579fs 11 121475905 121475905 HCC2157_BREAST 37 Frame_Shift_Del Del A - uc001pxx.2 SORL1_uc010rzp.... Hybrid_Cap...
SOS1 2 39278480 39278483 HCC2157_BREAST 37 Intron Del AAAC - uc002rrk.3 SOS1_uc010ynr.1... Hybrid_Cap...
STAT5A 17 40462797 40462800 HCC2157_BREAST 37 3'UTR Del TGTG - uc002hzj.1 STAT5A_uc010cya... Hybrid_Cap...
STK31 7 23872024 23872025 HCC2157_BREAST 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
STRADB 2 202319488 202319492 HCC2157_BREAST 37 5'UTR Del GAAAG - uc002uyd.3 Hybrid_Cap...
TEC 4 48139307 48139310 HCC2157_BREAST 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TLK1 2 171850178 171850179 HCC2157_BREAST 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TMEM123 11 102269398 102269398 HCC2157_BREAST 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNRC6B p.Q1328del 22 40697177 40697179 HCC2157_BREAST 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TP53 p.R248W 17 7577539 7577539 HCC2157_BREAST 37 Missense_Mutation SNP G A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 HCC2157_BREAST 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TPM3 1 154155467 154155467 HCC2157_BREAST 37 Intron SNP T C uc001fec.1 TPM3_uc010pei.1... Hybrid_Cap... view
TPO 2 1546405 1546405 HCC2157_BREAST 37 3'UTR SNP T G uc002qww.2 TPO_uc010ewj.2_... Hybrid_Cap... view
TPR p.D1151N 1 186313189 186313189 HCC2157_BREAST 37 Missense_Mutation SNP C T uc001grv.2 Hybrid_Cap... view
TRAF2 9 139820483 139820483 HCC2157_BREAST 37 3'UTR SNP C T uc010nbu.2 TRAF2_uc004cjv.... Hybrid_Cap... view
TSSK4 p.T338del 14 24677344 24677346 HCC2157_BREAST 37 In_Frame_Del Del ACG - rs79966000;rs56356156 uc001wnh.2 TM9SF1_uc010tob... Hybrid_Cap...
TTK 6 80752034 80752035 HCC2157_BREAST 37 3'UTR Ins - A uc003pjc.2 TTK_uc003pjb.3_... Hybrid_Cap...
TTN 2 179391639 179391640 HCC2157_BREAST 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.L14778P 2 179474000 179474000 HCC2157_BREAST 37 Missense_Mutation SNP A G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.P6955A 2 179583238 179583238 HCC2157_BREAST 37 Missense_Mutation SNP G C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
UBE3B 12 109947357 109947358 HCC2157_BREAST 37 Intron Ins - T uc001top.2 UBE3B_uc001toq.... Hybrid_Cap...
URB2 p.H851R 1 229772912 229772912 HCC2157_BREAST 37 Missense_Mutation SNP A G uc001hts.1 URB2_uc009xfd.1... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 HCC2157_BREAST 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
VPS13B p.P1004L 8 100403861 100403861 HCC2157_BREAST 37 Missense_Mutation SNP C T uc003yiv.2 VPS13B_uc003yiw... Hybrid_Cap... view