Annotation Summary for Cell Line: HCC-33  

Cell line primary name: HCC-33
Cell line aliases:
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: small_cell_carcinoma
Notes:
Source: DSMZ
Expression arrays: BITTS_p_NCLE_RNA12_HG-U133_Plus_2_B10_698916
SNP arrays: CHARY_p_NCLE_DNAAffy9_GenomeWideSNP_6_G04_490362
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in HCC-33

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 HCC33_LUNG 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM17 2 9630245 9630245 HCC33_LUNG 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 HCC33_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADCK1 14 78390632 78390637 HCC33_LUNG 37 Intron Del AAACT... - rs78274857;rs74969652 uc001xui.2 ADCK1_uc010tvo.... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 HCC33_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 HCC33_LUNG 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.E1166K 18 56203923 56203923 HCC33_LUNG 37 Missense_Mutation SNP C T uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap... view
ASTN1 p.R270C 1 177001649 177001649 HCC33_LUNG 37 Missense_Mutation SNP G A uc001glc.2 ASTN1_uc001glb.... Hybrid_Cap... view
BCR 22 23631813 23631814 HCC33_LUNG 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BMP4 14 54416601 54416602 HCC33_LUNG 37 3'UTR Ins - AT rs74495140;rs76335800 uc001xal.3 BMP4_uc010aoh.2... Hybrid_Cap...
BTG1 12 92537706 92537707 HCC33_LUNG 37 3'UTR Ins - T rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
CACNB2 10 18689903 18689903 HCC33_LUNG 37 Intron SNP G A uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap... view
CASP4 11 104839314 104839314 HCC33_LUNG 37 5'UTR SNP T G uc001pid.1 CASP4_uc009yxg.... Hybrid_Cap... view
CDK8 13 26978407 26978407 HCC33_LUNG 37 3'UTR SNP T A uc001uqr.1 CDK8_uc001uqs.1... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 HCC33_LUNG 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHIC2 4 54876132 54876132 HCC33_LUNG 37 3'UTR Del C - rs4437313 uc003haj.1 PDGFRA_uc003haa... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 HCC33_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 HCC33_LUNG 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
COL3A1 p.V160F 2 189851815 189851815 HCC33_LUNG 37 Missense_Mutation SNP G T uc002uqj.1 Hybrid_Cap... view
CREBBP p.A1824T 16 3779578 3779578 HCC33_LUNG 37 Missense_Mutation SNP C T uc002cvv.2 CREBBP_uc002cvw... Hybrid_Cap... view
CSMD3 p.G1907A 8 113418842 113418842 HCC33_LUNG 37 Missense_Mutation SNP C G uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CSMD3 8 114388966 114388966 HCC33_LUNG 37 Intron SNP C T uc003ynu.2 CSMD3_uc003ynt.... Hybrid_Cap... view
CTBP2 p.K974fs 10 126678123 126678123 HCC33_LUNG 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
CUBN p.P1425L 10 17032409 17032409 HCC33_LUNG 37 Missense_Mutation SNP G A uc001ioo.2 Hybrid_Cap... view
CXCL12 10 44873992 44873993 HCC33_LUNG 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
DACH1 13 72014625 72014626 HCC33_LUNG 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DAPK3 19 3961224 3961224 HCC33_LUNG 37 Intron SNP G A uc002lzc.1 DAPK3_uc002lzb.... Hybrid_Cap... view
DDR2 1 162750211 162750212 HCC33_LUNG 37 3'UTR Del TT - uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap...
DNAH8 p.L3513L 6 38897358 38897358 HCC33_LUNG 37 Silent SNP C T uc003ooe.1 DNAH8_uc003oog.... Hybrid_Cap... view
EGF p.Q246_splice 4 110866227 110866227 HCC33_LUNG 37 Splice_Site_SNP SNP A G uc003hzy.3 EGF_uc011cfu.1_... Hybrid_Cap... view
EGFR p.Q71L 7 55210102 55210102 HCC33_LUNG 37 Missense_Mutation SNP A T uc003tqk.2 EGFR_uc003tqh.2... Hybrid_Cap... view
EP300 22 41574970 41574972 HCC33_LUNG 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 HCC33_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EXT1 8 118811807 118811807 HCC33_LUNG 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
FAM132A 1 1177919 1177919 HCC33_LUNG 37 3'UTR Del T - uc001adl.1 Hybrid_Cap...
FASLG p.P31Q 1 172628433 172628434 HCC33_LUNG 37 Missense_Mutation DNP CC AG uc001gis.2 FASLG_uc001git.... Hybrid_Cap...
FBN1 p.C1263F 15 48776065 48776065 HCC33_LUNG 37 Missense_Mutation SNP C A uc001zwx.1 Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 HCC33_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 HCC33_LUNG 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FN1 2 216244182 216244185 HCC33_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GCNT2 6 10529044 10529044 HCC33_LUNG 37 De_novo_Start_OutOfFrame SNP C G uc010joo.2 GCNT2_uc010jol.... Hybrid_Cap... view
GPR141 p.L173F 7 37780512 37780512 HCC33_LUNG 37 Missense_Mutation SNP C T uc003tfm.1 Hybrid_Cap... view
GRIA3 X 122318386 122318387 HCC33_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRK6 5 176858839 176858839 HCC33_LUNG 37 Intron SNP C T uc011dfz.1 GRK6_uc003mgp.2... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 HCC33_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HDAC6 X 48664989 48664989 HCC33_LUNG 37 Intron SNP C T uc011mmi.1 HDAC6_uc004dks.... Hybrid_Cap... view
HECW1 p.P1541T 7 43594301 43594301 HCC33_LUNG 37 Missense_Mutation SNP C A uc003tid.1 HECW1_uc011kbi.... Hybrid_Cap... view
HIF1A 14 62213929 62213930 HCC33_LUNG 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 HCC33_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
IL21R 16 27460779 27460780 HCC33_LUNG 37 3'UTR Ins - TG rs66690088 uc002doq.1 IL21R_uc002dor.... Hybrid_Cap...
IL6ST 5 55236789 55236789 HCC33_LUNG 37 3'UTR SNP C G uc003jqq.2 IL6ST_uc010iwb.... Hybrid_Cap... view
ILK 11 6630029 6630029 HCC33_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
KIAA1409 p.C446Y 14 94038352 94038352 HCC33_LUNG 37 Missense_Mutation SNP G A uc001ybv.1 KIAA1409_uc001y... Hybrid_Cap... view
LRP6 p.I1144M 12 12291434 12291434 HCC33_LUNG 37 Missense_Mutation SNP G C uc001rah.3 BCL2L14_uc001ra... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 HCC33_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K3 p.A232_splice 17 21207866 21207866 HCC33_LUNG 37 Splice_Site_SNP SNP G A uc002gys.2 MAP2K3_uc002gyt... Hybrid_Cap... view
MAP3K1 p.T949del 5 56177849 56177851 HCC33_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 HCC33_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MCF2 p.R364C X 138699761 138699761 HCC33_LUNG 37 Missense_Mutation SNP G A uc011mwo.1 MCF2_uc004fau.2... Hybrid_Cap... view
MCM3APAS 21 47671308 47671308 HCC33_LUNG 37 3'UTR SNP A G uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap... view
MCM3APAS 21 47671275 47671276 HCC33_LUNG 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MFSD2A 1 40435515 40435515 HCC33_LUNG 37 3'UTR Del T - rs79314830 uc001cev.2 MFSD2A_uc001ceu... Hybrid_Cap...
MLL3 7 151833853 151833853 HCC33_LUNG 37 3'UTR SNP A T uc003wla.2 MLL3_uc003wkz.2... Hybrid_Cap... view
MLL3 p.P3082L 7 151873293 151873293 HCC33_LUNG 37 Missense_Mutation SNP G A rs61730545 uc003wla.2 MLL3_uc003wkz.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 HCC33_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 HCC33_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NDE1 16 15818685 15818685 HCC33_LUNG 37 3'UTR SNP G A uc010uzy.1 MYH11_uc002ddv.... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 HCC33_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 HCC33_LUNG 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NPR1 1 153665919 153665920 HCC33_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 HCC33_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 HCC33_LUNG 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PAX3 2 223158653 223158653 HCC33_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAXIP1 p.L360F 7 154760831 154760831 HCC33_LUNG 37 Missense_Mutation SNP T A uc003wlp.2 PAXIP1_uc003wlq... Hybrid_Cap... view
PDE4DIP 1 144863860 144863861 HCC33_LUNG 37 Intron Ins - T rs33949841 uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PER1 p.A416V 17 8051133 8051133 HCC33_LUNG 37 Missense_Mutation SNP G A uc002gkd.2 PER1_uc010vuq.1... Hybrid_Cap... view
PGR 11 100933598 100933599 HCC33_LUNG 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PHIP 6 79650265 79650266 HCC33_LUNG 37 3'UTR Ins - TTT rs70977753;rs13191571 uc003pir.2 PHIP_uc003piq.2... Hybrid_Cap...
PI4KA p.S1037F 22 21101950 21101950 HCC33_LUNG 37 Missense_Mutation SNP G A uc002zsz.3 Hybrid_Cap... view
PIK3CD 1 9787354 9787354 HCC33_LUNG 37 3'UTR SNP T G uc001aqe.3 PIK3CD_uc001aqb... Hybrid_Cap... view
PIK3CG p.W855L 7 106522587 106522587 HCC33_LUNG 37 Missense_Mutation SNP G T uc003vdv.3 PIK3CG_uc003vdu... Hybrid_Cap... view
PIP4K2A 10 22825887 22825887 HCC33_LUNG 37 3'UTR Del C - uc001irl.3 PIP4K2A_uc010qc... Hybrid_Cap...
PKMYT1 p.V289M 16 3025327 3025327 HCC33_LUNG 37 Missense_Mutation SNP C T uc002csn.2 PKMYT1_uc010uwn... Hybrid_Cap... view
PKN2 p.L384del 1 89250482 89250484 HCC33_LUNG 37 In_Frame_Del Del TCT - uc001dmn.2 PKN2_uc001dmm.1... Hybrid_Cap...
PMS1 2 190670539 190670540 HCC33_LUNG 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 HCC33_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTGS2 p.Q27K 1 186648544 186648544 HCC33_LUNG 37 Missense_Mutation SNP G T uc001gsb.2 PTGS2_uc009wyo.... Hybrid_Cap... view
PTPRD p.R1801S 9 8331713 8331713 HCC33_LUNG 37 Missense_Mutation SNP C A uc003zkk.2 PTPRD_uc003zkp.... Hybrid_Cap... view
RASGRF1 15 79277150 79277151 HCC33_LUNG 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RB1 p.I401fs 13 48947615 48947615 HCC33_LUNG 37 Frame_Shift_Del Del T - uc001vcb.2 RB1_uc010act.1_... Hybrid_Cap...
RBPJ p.R238* 4 26426291 26426291 HCC33_LUNG 37 Nonsense_Mutation SNP C T rs5007634 uc003grx.1 RBPJ_uc003gry.1... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 HCC33_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RHPN2 p.G99G 19 33517427 33517427 HCC33_LUNG 37 Silent SNP G A uc002nuf.2 RHPN2_uc010xro.... Hybrid_Cap... view
RIPK3 14 24808010 24808010 HCC33_LUNG 37 Intron SNP G A uc001wpb.2 RIPK3_uc001wpa.... Hybrid_Cap... view
RIPK4 p.R192C 21 43171306 43171306 HCC33_LUNG 37 Missense_Mutation SNP G A uc002yzn.1 Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 HCC33_LUNG 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
RUNX1 21 36421413 36421413 HCC33_LUNG 37 5'UTR Del A - uc010gmu.2 RUNX1_uc002yut.... Hybrid_Cap...
SGK494 p.G176R 17 26939657 26939657 HCC33_LUNG 37 Missense_Mutation SNP C T uc002hbr.1 SGK494_uc010waq... Hybrid_Cap... view
SLC22A15 1 116574276 116574276 HCC33_LUNG 37 Intron SNP C G uc001egb.3 SLC22A15_uc001e... Hybrid_Cap... view
SMC2 p.K466R 9 106875739 106875739 HCC33_LUNG 37 Missense_Mutation SNP A G uc004bbv.2 SMC2_uc004bbu.1... Hybrid_Cap... view
SMO p.S574C 7 128850874 128850874 HCC33_LUNG 37 Missense_Mutation SNP C G uc003vor.2 SMO_uc003vos.2_... Hybrid_Cap... view
SMURF2 17 62541865 62541865 HCC33_LUNG 37 3'UTR Del A - rs3210656 uc002jep.1 SMURF2_uc002jeq... Hybrid_Cap...
SP140 p.R20_splice 2 231101796 231101796 HCC33_LUNG 37 Splice_Site_SNP SNP A T uc002vql.2 SP140_uc010zma.... Hybrid_Cap... view
SPRY2 p.Q76* 13 80911615 80911615 HCC33_LUNG 37 Nonsense_Mutation SNP G A uc001vli.2 SPRY2_uc001vlj.... Hybrid_Cap... view
STK31 p.E433* 7 23802423 23802423 HCC33_LUNG 37 Nonsense_Mutation SNP G T uc003sws.3 STK31_uc003swt.... Hybrid_Cap... view
STK31 7 23872024 23872025 HCC33_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
STK32B p.P346T 4 5468556 5468556 HCC33_LUNG 37 Missense_Mutation SNP C A uc003gih.1 STK32B_uc010ida... Hybrid_Cap... view
TCF21 6 134210497 134210498 HCC33_LUNG 37 5'UTR Ins - TC rs35199378 uc003qei.3 TCF21_uc003qej.... Hybrid_Cap...
TGFB2 1 218519928 218519929 HCC33_LUNG 37 5'UTR Ins - AAAC uc001hln.2 TGFB2_uc001hll.... Hybrid_Cap...
TMEM123 11 102269398 102269398 HCC33_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TMEM123 11 102269461 102269461 HCC33_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNFRSF1B p.C110F 1 12251852 12251852 HCC33_LUNG 37 Missense_Mutation SNP G T uc001att.2 TNFRSF1B_uc001a... Hybrid_Cap... view
TNFRSF1B p.T111S 1 12251854 12251854 HCC33_LUNG 37 Missense_Mutation SNP A T uc001att.2 TNFRSF1B_uc001a... Hybrid_Cap... view
TP53 p.C242Y 17 7577556 7577556 HCC33_LUNG 37 Missense_Mutation SNP C T uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM36 5 114462143 114462143 HCC33_LUNG 37 3'UTR SNP A C uc003kqs.2 TRIM36_uc011cwc... Hybrid_Cap... view
TRPS1 8 116635872 116635873 HCC33_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TSSK2 p.V14A 22 19118953 19118953 HCC33_LUNG 37 Missense_Mutation SNP T C uc002zow.2 DGCR14_uc002zot... Hybrid_Cap... view
TTN p.A8187D 2 179575532 179575532 HCC33_LUNG 37 Missense_Mutation SNP G T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 HCC33_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
ZNF217 p.P594T 20 52193523 52193523 HCC33_LUNG 37 Missense_Mutation SNP G T uc002xwq.3 ZNF217_uc010gij... Hybrid_Cap... view