Annotation Summary for Cell Line: HCC-44  

Cell line primary name: HCC-44
Cell line aliases:
Gender: F
Site Primary: lung
Histology: carcinoma
Hist Subtype1: adenocarcinoma
Notes:
Source: DSMZ
Expression arrays: NIECE_p_NCLE_RNA3_HG-U133_Plus_2_B04_302134
SNP arrays: HONEY_p_NCLE_DNAAffy3_S_GenomeWideSNP_6_F01_293400
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in HCC-44

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABCC4 p.Q387* 13 95858788 95858788 HCC44_LUNG 37 Nonsense_Mutation SNP G A uc001vmd.3 ABCC4_uc010afk.... Hybrid_Cap... view
ABL2 p.G300V 1 179090791 179090791 HCC44_LUNG 37 Missense_Mutation SNP C A uc001gmj.3 ABL2_uc010pnf.1... Hybrid_Cap... view
ACVR1 p.T298S 2 158622606 158622606 HCC44_LUNG 37 Missense_Mutation SNP G C uc002tzm.3 ACVR1_uc002tzn.... Hybrid_Cap... view
ADAM18 8 39468365 39468365 HCC44_LUNG 37 Intron SNP G T uc003xni.2 ADAM18_uc003xnh... Hybrid_Cap... view
ADAM28 8 24211994 24211997 HCC44_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 HCC44_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.K2854N 7 91712885 91712885 HCC44_LUNG 37 Missense_Mutation SNP G C uc003ulg.2 AKAP9_uc003ulf.... Hybrid_Cap... view
ALPK1 4 113347609 113347610 HCC44_LUNG 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
AURKC 19 57742494 57742507 HCC44_LUNG 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
AXIN1 p.N605K 16 347196 347196 HCC44_LUNG 37 Missense_Mutation SNP A T uc002cgp.1 AXIN1_uc002cgq.... Hybrid_Cap... view
BCL3 p.P407fs 19 45262726 45262729 HCC44_LUNG 37 Frame_Shift_Del Del CCCC - uc010xxe.1 Hybrid_Cap...
BCR 22 23631813 23631814 HCC44_LUNG 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BCR 22 23632777 23632778 HCC44_LUNG 37 Intron Ins - T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
CDC42BPB p.F336L 14 103447242 103447242 HCC44_LUNG 37 Missense_Mutation SNP G C uc001ymi.1 Hybrid_Cap... view
CDK11B 1 1654066 1654068 HCC44_LUNG 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CHD1 p.P1684del 5 98192165 98192167 HCC44_LUNG 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHN1 p.G52C 2 175779892 175779892 HCC44_LUNG 37 Missense_Mutation SNP C A uc002uji.2 CHN1_uc010zeq.1... Hybrid_Cap... view
CLK4 p.R156K 5 178044353 178044353 HCC44_LUNG 37 Missense_Mutation SNP C T uc003mjf.1 CLK4_uc003mjg.1... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 HCC44_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 HCC44_LUNG 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CNTN6 p.G343* 3 1367579 1367579 HCC44_LUNG 37 Nonsense_Mutation SNP G T uc003boz.2 CNTN6_uc011asj.... Hybrid_Cap... view
CSF1R 5 149456826 149456826 HCC44_LUNG 37 Intron Del C - uc003lrl.2 CSF1R_uc011dcd.... Hybrid_Cap...
CSMD3 p.T602S 8 113841970 113841970 HCC44_LUNG 37 Missense_Mutation SNP T A uc003ynu.2 CSMD3_uc003ynt.... Hybrid_Cap... view
CXCL12 10 44873992 44873993 HCC44_LUNG 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
CYLD 16 50830558 50830558 HCC44_LUNG 37 3'UTR SNP G A uc002egp.1 CYLD_uc002egq.1... Hybrid_Cap... view
DCLK3 3 36756680 36756680 HCC44_LUNG 37 3'UTR SNP T C uc003cgi.2 Hybrid_Cap... view
DFNA5 7 24784095 24784095 HCC44_LUNG 37 Intron SNP C T uc010kus.1 DFNA5_uc003swz.... Hybrid_Cap... view
DYRK1A p.D73H 21 38850492 38850492 HCC44_LUNG 37 Missense_Mutation SNP G C uc002ywk.2 DYRK1A_uc002ywh... Hybrid_Cap... view
EIF2B5 p.L127L 3 183855468 183855468 HCC44_LUNG 37 Silent SNP C G uc003fmp.2 EIF2B5_uc003fmq... Hybrid_Cap... view
EP300 p.Q2004H 22 41573727 41573727 HCC44_LUNG 37 Missense_Mutation SNP G T uc003azl.3 Hybrid_Cap... view
EP300 22 41574970 41574972 HCC44_LUNG 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 HCC44_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHB6 p.Y132* 7 142561954 142561954 HCC44_LUNG 37 Nonsense_Mutation SNP C A uc011kst.1 EPHB6_uc011ksu.... Hybrid_Cap... view
ERCC6 p.S797C 10 50682281 50682281 HCC44_LUNG 37 Missense_Mutation SNP G C uc001jhs.3 ERCC6_uc009xod.... Hybrid_Cap... view
FANCA 16 89865404 89865404 HCC44_LUNG 37 Intron SNP C T rs45494792 uc002fou.1 FANCA_uc010vpn.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 HCC44_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 HCC44_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FNBP1 9 132658032 132658032 HCC44_LUNG 37 Intron SNP C G uc004byw.1 FNBP1_uc011mbv.... Hybrid_Cap... view
FOXP1 3 71008341 71008342 HCC44_LUNG 37 3'UTR Ins - T rs11433724;rs114233617 uc003dol.2 FOXP1_uc003dom.... Hybrid_Cap...
FSCB p.G382C 14 44975047 44975047 HCC44_LUNG 37 Missense_Mutation SNP C A uc001wvn.2 Hybrid_Cap... view
GCK p.K91N 7 44191963 44191963 HCC44_LUNG 37 Missense_Mutation SNP C G uc003tkk.1 GCK_uc003tkj.1_... Hybrid_Cap... view
GPR112 X 135498771 135498771 HCC44_LUNG 37 3'UTR SNP T A uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap... view
GRIA3 X 122318386 122318387 HCC44_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIK1 p.V567fs 21 30959780 30959780 HCC44_LUNG 37 Frame_Shift_Del Del C - uc011acs.1 GRIK1_uc002ynn.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 HCC44_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HERC2 p.A204A 15 28520082 28520082 HCC44_LUNG 37 Silent SNP G A uc001zbj.2 HERC2_uc001zbl.... Hybrid_Cap... view
HIF1A 14 62213929 62213930 HCC44_LUNG 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
ILK 11 6630029 6630029 HCC44_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ISG15 1 948846 948847 HCC44_LUNG 37 5'UTR Ins - A rs33916361 uc001acj.3 Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 HCC44_LUNG 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KLK7 19 51480672 51480675 HCC44_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KRAS p.G12C 12 25398285 25398285 HCC44_LUNG 37 Missense_Mutation SNP C A uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
LRP1B p.D2827N 2 141264407 141264407 HCC44_LUNG 37 Missense_Mutation SNP C T uc002tvj.1 Hybrid_Cap... view
LZTR1 p.V218_splice 22 21344674 21344674 HCC44_LUNG 37 Splice_Site_SNP SNP G T uc002zto.2 LZTR1_uc002ztn.... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 HCC44_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 HCC44_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 HCC44_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPK14 6 36076345 36076354 HCC44_LUNG 37 3'UTR Del GTGTG... - rs80147786 uc003olp.2 MAPK14_uc003olq... Hybrid_Cap...
MAPKAPK3 3 50685575 50685575 HCC44_LUNG 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MITF p.E66* 3 69928376 69928376 HCC44_LUNG 37 Nonsense_Mutation SNP G T uc003dnz.2 MITF_uc011bgb.1... Hybrid_Cap... view
MKNK1 p.F124Y 1 47040636 47040636 HCC44_LUNG 37 Missense_Mutation SNP A T uc001cqb.2 MKNK1_uc010omd.... Hybrid_Cap... view
MSH3 p.PPA66del 5 79950742 79950750 HCC44_LUNG 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
NCAM1 11 112832307 112832308 HCC44_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 HCC44_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 p.V79I 11 113146062 113146062 HCC44_LUNG 37 Missense_Mutation SNP G A uc001pnt.2 NCAM1_uc001pns.... Hybrid_Cap... view
NEK11 p.R426W 3 130887773 130887773 HCC44_LUNG 37 Missense_Mutation SNP A T uc003eny.2 NEK11_uc003enx.... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 HCC44_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NOTCH1 p.E851G 9 139405639 139405639 HCC44_LUNG 37 Missense_Mutation SNP T C uc004chz.2 NOTCH1_uc004cia... Hybrid_Cap... view
NOTCH4 6 32170465 32170465 HCC44_LUNG 37 Intron Del G - uc003obb.2 NOTCH4_uc003oba... Hybrid_Cap...
NPR1 1 153665919 153665920 HCC44_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 HCC44_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 HCC44_LUNG 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NTRK3 p.H729N 15 88423650 88423650 HCC44_LUNG 37 Missense_Mutation SNP G T uc002bme.1 NTRK3_uc002bmh.... Hybrid_Cap... view
NTRK3 p.P498H 15 88576180 88576180 HCC44_LUNG 37 Missense_Mutation SNP G T uc002bme.1 NTRK3_uc002bmh.... Hybrid_Cap... view
PAPPA p.S1077F 9 119093605 119093605 HCC44_LUNG 37 Missense_Mutation SNP C T uc004bjn.2 PAPPA_uc011lxp.... Hybrid_Cap... view
PDE4DIP p.Q1665fs 1 144873963 144873963 HCC44_LUNG 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.V486fs 1 144917828 144917828 HCC44_LUNG 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP 1 144931723 144931723 HCC44_LUNG 37 Intron SNP G T uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 HCC44_LUNG 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PPP3R2 9 104356664 104356664 HCC44_LUNG 37 3'UTR SNP G A uc004bbr.2 GRIN3A_uc004bbp... Hybrid_Cap... view
PRKCB 16 24231211 24231211 HCC44_LUNG 37 3'UTR SNP A G uc002dme.2 PRKCB_uc002dmd.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 HCC44_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RGS22 p.R1204L 8 100977567 100977567 HCC44_LUNG 37 Missense_Mutation SNP C A uc003yjb.1 RGS22_uc003yja.... Hybrid_Cap... view
RIOK3 p.V38L 18 21042976 21042976 HCC44_LUNG 37 Missense_Mutation SNP G T uc002kui.3 RIOK3_uc010dls.... Hybrid_Cap... view
RIPK4 p.S30P 21 43187114 43187114 HCC44_LUNG 37 Missense_Mutation SNP A G uc002yzn.1 Hybrid_Cap... view
RPS6KA5 14 91360733 91360734 HCC44_LUNG 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
SMURF2 17 62541852 62541852 HCC44_LUNG 37 3'UTR Del G - rs2872314 uc002jep.1 SMURF2_uc002jeq... Hybrid_Cap...
SPEG p.P2916L 2 220354487 220354487 HCC44_LUNG 37 Missense_Mutation SNP C T uc010fwg.2 Hybrid_Cap... view
STK31 7 23872024 23872025 HCC44_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
SUFU 10 104390053 104390053 HCC44_LUNG 37 3'UTR SNP T G uc001kvy.1 SUFU_uc009xxe.1... Hybrid_Cap... view
TFRC p.G347_splice 3 195792473 195792473 HCC44_LUNG 37 Splice_Site_SNP SNP T C uc003fvz.3 TFRC_uc003fwa.3... Hybrid_Cap... view
TGFBR1 p.K449N 9 101910027 101910027 HCC44_LUNG 37 Missense_Mutation SNP G T uc004azc.2 TGFBR1_uc004azd... Hybrid_Cap... view
TMEM123 11 102269398 102269398 HCC44_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNRC6B p.Q1328del 22 40697177 40697179 HCC44_LUNG 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TP53 p.R175L 17 7578406 7578406 HCC44_LUNG 37 Missense_Mutation SNP C A rs28934578 uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 HCC44_LUNG 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TPM3 1 154155465 154155465 HCC44_LUNG 37 Intron SNP T A uc001fec.1 TPM3_uc010pei.1... Hybrid_Cap... view
TRPS1 8 116635872 116635873 HCC44_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN p.I29189T 2 179410693 179410693 HCC44_LUNG 37 Missense_Mutation SNP A G rs72648259 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.V27228M 2 179418346 179418346 HCC44_LUNG 37 Missense_Mutation SNP C T rs72648237 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.F24187L 2 179430596 179430596 HCC44_LUNG 37 Missense_Mutation SNP A G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.L3757F 2 179599650 179599650 HCC44_LUNG 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.A3454_splice 2 179603088 179603088 HCC44_LUNG 37 Splice_Site_SNP SNP C A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TUFT1 p.R285W 1 151551231 151551231 HCC44_LUNG 37 Missense_Mutation SNP C T uc001eyl.2 TUFT1_uc001eym.... Hybrid_Cap... view
VCPIP1 p.I170L 8 67578686 67578686 HCC44_LUNG 37 Missense_Mutation SNP T A uc003xwn.2 SGK3_uc003xwp.2... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 HCC44_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
VEGFC p.T273K 4 177608668 177608668 HCC44_LUNG 37 Missense_Mutation SNP G T uc003ius.1 Hybrid_Cap... view
VPS13B p.W350L 8 100133516 100133516 HCC44_LUNG 37 Missense_Mutation SNP G T uc003yiv.2 VPS13B_uc003yiw... Hybrid_Cap... view