Annotation Summary for Cell Line: HCC-56  

Cell line primary name: HCC-56
Cell line aliases:
Gender:
Site Primary: large_intestine
Histology: carcinoma
Hist Subtype1: adenocarcinoma
Notes:
Source: HSRRB
Expression arrays: MAKER_p_NCLE_RNA7_HG-U133_Plus_2_C11_454630
SNP arrays: BOWER_p_NCLE_DNAAffy8_GenomeWideSNP_6_E01_464724
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in HCC-56

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 HCC56_LARGE_INT... 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM22 p.E287D 7 87757943 87757943 HCC56_LARGE_INT... 37 Missense_Mutation SNP A T uc003ujp.1 ADAM22_uc003uji... Hybrid_Cap... view
ADAM28 8 24211994 24211997 HCC56_LARGE_INT... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 HCC56_LARGE_INT... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.D2123D 7 91699382 91699382 HCC56_LARGE_INT... 37 Silent SNP C T uc003ulg.2 AKAP9_uc003ulf.... Hybrid_Cap... view
ALPK1 4 113347609 113347610 HCC56_LARGE_INT... 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ASPH p.A264_splice 8 62550924 62550925 HCC56_LARGE_INT... 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
ATM p.C2337Y 11 108198406 108198406 HCC56_LARGE_INT... 37 Missense_Mutation SNP G A uc001pkb.1 ATM_uc009yxr.1_... Hybrid_Cap... view
AURKC 19 57742494 57742507 HCC56_LARGE_INT... 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BCL9 p.P528fs 1 147091545 147091546 HCC56_LARGE_INT... 37 Frame_Shift_Ins Ins - G uc001epq.2 BCL9_uc010ozr.1... Hybrid_Cap...
BRCA2 p.A2351G 13 32929042 32929042 HCC56_LARGE_INT... 37 Missense_Mutation SNP C G rs80358932 uc001uub.1 Hybrid_Cap... view
BRD2 6 32948607 32948608 HCC56_LARGE_INT... 37 3'UTR Ins - T rs1049414;rs114195059 uc010juh.2 BRD2_uc003ocn.3... Hybrid_Cap...
CACNB2 10 18828721 18828722 HCC56_LARGE_INT... 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CASP4 11 104819546 104819547 HCC56_LARGE_INT... 37 Intron Ins - AGACACAC rs33910737;rs113139978 uc001pid.1 CASP4_uc001pib.... Hybrid_Cap...
CDK11B p.D46N 1 1653126 1653126 HCC56_LARGE_INT... 37 Missense_Mutation SNP C T uc001agv.1 CDK11B_uc001aha... Hybrid_Cap... view
CHD8 p.V75L 14 21897278 21897278 HCC56_LARGE_INT... 37 Missense_Mutation SNP C A uc001was.1 CHD8_uc001war.1... Hybrid_Cap... view
CHRNA5 15 78885615 78885616 HCC56_LARGE_INT... 37 3'UTR Ins - TA rs72534078 uc002bdy.2 CHRNA3_uc002bea... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 HCC56_LARGE_INT... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 HCC56_LARGE_INT... 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 HCC56_LARGE_INT... 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CYLD 16 50820672 50820673 HCC56_LARGE_INT... 37 Intron Ins - A rs117241863 uc002egp.1 CYLD_uc002ego.2... Hybrid_Cap...
DACH1 13 72014625 72014626 HCC56_LARGE_INT... 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DDR2 1 162750211 162750212 HCC56_LARGE_INT... 37 3'UTR Del TT - uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap...
DGKB 7 14216345 14216346 HCC56_LARGE_INT... 37 Intron Ins - AGACT uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap...
DNAH8 p.E1904Q 6 38831699 38831699 HCC56_LARGE_INT... 37 Missense_Mutation SNP G C uc003ooe.1 Hybrid_Cap... view
EDN1 6 12290729 12290729 HCC56_LARGE_INT... 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EGF p.E1134fs 4 110932389 110932390 HCC56_LARGE_INT... 37 Frame_Shift_Ins Ins - C rs11569144 uc003hzy.3 EGF_uc011cfu.1_... Hybrid_Cap...
EPHA6 3 97367230 97367231 HCC56_LARGE_INT... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ETV1 7 14028708 14028708 HCC56_LARGE_INT... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FBXO43 p.G559W 8 101146592 101146592 HCC56_LARGE_INT... 37 Missense_Mutation SNP C A uc003yjd.2 FBXO43_uc003yje... Hybrid_Cap... view
FMN2 p.P914H 1 240370841 240370841 HCC56_LARGE_INT... 37 Missense_Mutation SNP C A uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap... view
FN1 2 216244182 216244185 HCC56_LARGE_INT... 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GLI1 p.P579T 12 57864258 57864258 HCC56_LARGE_INT... 37 Missense_Mutation SNP C A uc001snx.2 GLI1_uc009zpq.2... Hybrid_Cap... view
GOLGA5 p.S461R 14 93282656 93282656 HCC56_LARGE_INT... 37 Missense_Mutation SNP A C uc001yaz.1 Hybrid_Cap... view
GOLGA5 p.Q557K 14 93290939 93290939 HCC56_LARGE_INT... 37 Missense_Mutation SNP C A uc001yaz.1 Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 HCC56_LARGE_INT... 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GPR141 p.H4R 7 37780006 37780006 HCC56_LARGE_INT... 37 Missense_Mutation SNP A G uc003tfm.1 Hybrid_Cap... view
GRIA3 X 122318386 122318387 HCC56_LARGE_INT... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 HCC56_LARGE_INT... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HERC2 p.S2559G 15 28446643 28446643 HCC56_LARGE_INT... 37 Missense_Mutation SNP T C rs61756158 uc001zbj.2 HERC2_uc001zbk.... Hybrid_Cap... view
HIF1A 14 62213929 62213930 HCC56_LARGE_INT... 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HSP90B1 p.E791del 12 104341188 104341190 HCC56_LARGE_INT... 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 HCC56_LARGE_INT... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
KALRN 3 124207283 124207283 HCC56_LARGE_INT... 37 Intron SNP A G uc003ehg.2 KALRN_uc010hrv.... Hybrid_Cap... view
KRAS p.G12V 12 25398284 25398284 HCC56_LARGE_INT... 37 Missense_Mutation SNP C A uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
LATS2 13 21620222 21620223 HCC56_LARGE_INT... 37 5'UTR Ins - A rs61240127;rs115723063 uc009zzs.2 LATS2_uc001unr.... Hybrid_Cap...
LRP2 p.V2506I 2 170062573 170062573 HCC56_LARGE_INT... 37 Missense_Mutation SNP C T uc002ues.2 Hybrid_Cap... view
LRP2 p.A706_splice 2 170127619 170127619 HCC56_LARGE_INT... 37 Splice_Site_SNP SNP T C uc002ues.2 LRP2_uc010zdf.1... Hybrid_Cap... view
LRRK2 p.N238I 12 40637358 40637358 HCC56_LARGE_INT... 37 Missense_Mutation SNP A T rs28365216 uc001rmg.3 Hybrid_Cap... view
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 HCC56_LARGE_INT... 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 HCC56_LARGE_INT... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 HCC56_LARGE_INT... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 HCC56_LARGE_INT... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPK14 6 36076345 36076354 HCC56_LARGE_INT... 37 3'UTR Del GTGTG... - rs80147786 uc003olp.2 MAPK14_uc003olq... Hybrid_Cap...
MAPKBP1 15 42111753 42111754 HCC56_LARGE_INT... 37 Intron Ins - C rs3034891 uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap...
MGA p.A625E 15 41989082 41989082 HCC56_LARGE_INT... 37 Missense_Mutation SNP C A uc010ucy.1 MGA_uc001zog.1_... Hybrid_Cap... view
MLL3 p.Q3056E 7 151873372 151873372 HCC56_LARGE_INT... 37 Missense_Mutation SNP G C uc003wla.2 MLL3_uc003wkz.2... Hybrid_Cap... view
MLL3 p.Y816fs 7 151945071 151945072 HCC56_LARGE_INT... 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
MLLT3 9 20346393 20346394 HCC56_LARGE_INT... 37 3'UTR Ins - A uc003zoe.2 MLLT3_uc011lne.... Hybrid_Cap...
MRE11A p.I396T 11 94197317 94197317 HCC56_LARGE_INT... 37 Missense_Mutation SNP A G uc001peu.2 MRE11A_uc001pev... Hybrid_Cap... view
MTMR11 1 149900881 149900881 HCC56_LARGE_INT... 37 3'UTR SNP G A uc001etl.3 SF3B4_uc001eti.... Hybrid_Cap... view
MYH10 p.R1576K 17 8393815 8393815 HCC56_LARGE_INT... 37 Missense_Mutation SNP C T uc002glm.2 MYH10_uc002gll.... Hybrid_Cap... view
MYLK p.E1066del 3 123419117 123419119 HCC56_LARGE_INT... 37 In_Frame_Del Del TTC - rs72491150 uc003ego.2 MYLK_uc011bjw.1... Hybrid_Cap...
MYO3A p.P228T 10 26310528 26310528 HCC56_LARGE_INT... 37 Missense_Mutation SNP C A uc001isn.2 MYO3A_uc009xko.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 HCC56_LARGE_INT... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 HCC56_LARGE_INT... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 HCC56_LARGE_INT... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 HCC56_LARGE_INT... 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NPR1 1 153665919 153665920 HCC56_LARGE_INT... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NPRL2 3 50384978 50384978 HCC56_LARGE_INT... 37 3'UTR Del C - rs75013672 uc003daj.1 ZMYND10_uc003da... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 HCC56_LARGE_INT... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR3C1 5 142780419 142780419 HCC56_LARGE_INT... 37 Splice_Site_SNP SNP T A uc003lmy.2 NR3C1_uc003lmz.... Hybrid_Cap... view
NTRK1 p.R593W 1 156846336 156846336 HCC56_LARGE_INT... 37 Missense_Mutation SNP C T uc001fqh.1 NTRK1_uc001fqf.... Hybrid_Cap... view
OBSCN p.V1930M 1 228462377 228462377 HCC56_LARGE_INT... 37 Missense_Mutation SNP G A uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
OR4E2 p.A242S 14 22134020 22134020 HCC56_LARGE_INT... 37 Missense_Mutation SNP G T uc010tmd.1 Hybrid_Cap... view
PALB2 p.E211G 16 23647235 23647235 HCC56_LARGE_INT... 37 Missense_Mutation SNP T C uc002dlx.1 Hybrid_Cap... view
PAX3 2 223066017 223066018 HCC56_LARGE_INT... 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX5 9 37034095 37034095 HCC56_LARGE_INT... 37 5'UTR Del C - uc003zzo.1 PAX5_uc011lpw.1... Hybrid_Cap...
PCDH15 p.G1156R 10 55663053 55663053 HCC56_LARGE_INT... 37 Missense_Mutation SNP C T uc010qhy.1 PCDH15_uc010qhq... Hybrid_Cap... view
PDE4DIP 1 144852415 144852415 HCC56_LARGE_INT... 37 3'UTR SNP T A uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PDE4DIP 1 144863620 144863620 HCC56_LARGE_INT... 37 Intron SNP A G uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PDE4DIP 1 144892080 144892080 HCC56_LARGE_INT... 37 Intron SNP C T uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PDE4DIP p.E243fs 1 144923729 144923729 HCC56_LARGE_INT... 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PPP1R3A p.S1109P 7 113517822 113517822 HCC56_LARGE_INT... 37 Missense_Mutation SNP A G uc010ljy.1 Hybrid_Cap... view
PRKCA 17 64298959 64298960 HCC56_LARGE_INT... 37 5'UTR Ins - G rs71160558 uc002jfp.1 PRKCA_uc002jfo.... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 HCC56_LARGE_INT... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG1 10 52751088 52751089 HCC56_LARGE_INT... 37 5'UTR Ins - GCT rs67900156;rs71029335 uc001jjm.2 PRKG1_uc010qhp.... Hybrid_Cap...
PXDN p.A1059T 2 1652377 1652377 HCC56_LARGE_INT... 37 Missense_Mutation SNP C T uc002qxa.2 Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 HCC56_LARGE_INT... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RIF1 p.A2128V 2 152322417 152322417 HCC56_LARGE_INT... 37 Missense_Mutation SNP C T uc002txm.2 RIF1_uc002txl.2... Hybrid_Cap... view
ROR2 p.E703D 9 94486667 94486667 HCC56_LARGE_INT... 37 Missense_Mutation SNP C A uc004arj.1 ROR2_uc004ari.1... Hybrid_Cap... view
RXRA p.T23T 9 137293518 137293518 HCC56_LARGE_INT... 37 Silent SNP G A uc004cfb.2 RXRA_uc004cfa.1... Hybrid_Cap... view
SGK223 p.K787T 8 8185932 8185932 HCC56_LARGE_INT... 37 Missense_Mutation SNP T G uc003wsh.3 Hybrid_Cap... view
SLCO4A1 p.P332S 20 61291870 61291870 HCC56_LARGE_INT... 37 Missense_Mutation SNP C T uc002ydb.1 SLCO4A1_uc002yd... Hybrid_Cap... view
SOX2 3 181431226 181431227 HCC56_LARGE_INT... 37 3'UTR Ins - A rs80135245 uc003fkx.2 SOX2OT_uc003fkv... Hybrid_Cap...
STK31 7 23872024 23872025 HCC56_LARGE_INT... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TEC 4 48139307 48139310 HCC56_LARGE_INT... 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TFRC p.A102K 3 195800930 195800931 HCC56_LARGE_INT... 37 Missense_Mutation DNP GC TT uc003fvz.3 TFRC_uc003fwa.3... Hybrid_Cap...
TG p.L824V 8 133900522 133900522 HCC56_LARGE_INT... 37 Missense_Mutation SNP C G uc003ytw.2 Hybrid_Cap... view
TGFB2 p.I428F 1 218614657 218614657 HCC56_LARGE_INT... 37 Missense_Mutation SNP A T uc001hln.2 TGFB2_uc001hlm.... Hybrid_Cap... view
TLN1 p.A1173P 9 35712876 35712876 HCC56_LARGE_INT... 37 Missense_Mutation SNP C G uc003zxt.2 Hybrid_Cap... view
TNFRSF12A p.E120Q 16 3071795 3071795 HCC56_LARGE_INT... 37 Missense_Mutation SNP G C uc002csv.3 TNFRSF12A_uc002... Hybrid_Cap... view
TP53 p.R196P 17 7578262 7578262 HCC56_LARGE_INT... 37 Missense_Mutation SNP C G uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
UNC13C p.H536Q 15 54306708 54306708 HCC56_LARGE_INT... 37 Missense_Mutation SNP C G uc002ack.2 Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 HCC56_LARGE_INT... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...