Annotation Summary for Cell Line: HOS  

Cell line primary name: HOS
Cell line aliases:
Gender: F
Site Primary: bone
Histology: osteosarcoma
Hist Subtype1: NS
Notes: Identical lines: HTK-, HOS and 143B share high SNP identity and are very likely to be osteosarcoma
Source: ATCC
Expression arrays: AGENT_p_NCLE_RNA6_HG-U133_Plus_2_A08_436610
SNP arrays: BOWER_p_NCLE_DNAAffy8_GenomeWideSNP_6_H09_464634
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in HOS

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM17 2 9630245 9630245 HOS_BONE 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM18 p.N727fs 8 39587420 39587429 HOS_BONE 37 Frame_Shift_Del Del TTCAT... - uc003xni.2 ADAM18_uc010lww... Hybrid_Cap...
ADAM28 8 24211994 24211997 HOS_BONE 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 HOS_BONE 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK1 4 113347609 113347610 HOS_BONE 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 HOS_BONE 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ALPK3 p.K970N 15 85400273 85400273 HOS_BONE 37 Missense_Mutation SNP A T uc002ble.2 Hybrid_Cap... view
ASPH 8 62602296 62602296 HOS_BONE 37 Intron Del A - uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
BCR 22 23631813 23631814 HOS_BONE 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BCR 22 23632777 23632778 HOS_BONE 37 Intron Ins - T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BRD2 6 32948605 32948605 HOS_BONE 37 3'UTR SNP C T uc010juh.2 BRD2_uc003ocn.3... Hybrid_Cap... view
BTG1 12 92537706 92537707 HOS_BONE 37 3'UTR Ins - T rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
CASC5 15 40917890 40917890 HOS_BONE 37 Intron SNP G A uc010bbs.1 CASC5_uc001zme.... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 HOS_BONE 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHD8 p.R1551C 14 21862547 21862547 HOS_BONE 37 Missense_Mutation SNP G A uc001was.1 CHD8_uc001war.1... Hybrid_Cap... view
CIITA p.D297E 16 10997703 10997703 HOS_BONE 37 Missense_Mutation SNP C A uc002daj.3 CIITA_uc002dai.... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 HOS_BONE 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CTBP2 p.R134W 10 126715929 126715929 HOS_BONE 37 Missense_Mutation SNP G A uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap... view
CUBN p.G2556D 10 16949545 16949545 HOS_BONE 37 Missense_Mutation SNP C T uc001ioo.2 CUBN_uc009xjq.1... Hybrid_Cap... view
CXCR4 2 136873548 136873549 HOS_BONE 37 5'UTR DNP AA TT rs2680880 uc002tuy.2 CXCR4_uc010fnk.... Hybrid_Cap...
CYP27B1 12 58156848 58156848 HOS_BONE 37 3'UTR SNP C T rs8176350 uc001spz.1 CYP27B1_uc001sq... Hybrid_Cap... view
DACH1 13 72014625 72014626 HOS_BONE 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DDR2 1 162750211 162750211 HOS_BONE 37 3'UTR Del T - uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap...
DIP2C 10 428447 428448 HOS_BONE 37 Intron Del AG - uc001ifp.2 DIP2C_uc009xhj.... Hybrid_Cap...
DLC1 8 13162666 13162666 HOS_BONE 37 Intron SNP C T uc003wwm.2 DLC1_uc003wwn.2... Hybrid_Cap... view
DST p.G2556V 6 56426980 56426980 HOS_BONE 37 Missense_Mutation SNP C A uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
DYRK1A 21 38884966 38884967 HOS_BONE 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EIF4G1 p.P252S 3 184039105 184039105 HOS_BONE 37 Missense_Mutation SNP C T uc010hxx.2 EIF4G1_uc003fno... Hybrid_Cap... view
EP300 22 41574970 41574972 HOS_BONE 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA5 4 66189753 66189754 HOS_BONE 37 3'UTR Ins - T rs67487372 uc011cah.1 EPHA5_uc003hcx.... Hybrid_Cap...
EPHA6 3 97367230 97367231 HOS_BONE 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHB1 p.I439I 3 134873013 134873013 HOS_BONE 37 Silent SNP C T uc003eqt.2 EPHB1_uc003equ.... Hybrid_Cap... view
EPHB4 p.R889G 7 100403136 100403136 HOS_BONE 37 Missense_Mutation SNP G C uc003uwn.1 EPHB4_uc003uwm.... Hybrid_Cap... view
ETV1 7 14028708 14028708 HOS_BONE 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FANCF p.R50W 11 22647209 22647209 HOS_BONE 37 Missense_Mutation SNP G A uc001mql.1 Hybrid_Cap... view
FASLG p.F87L 1 172628600 172628600 HOS_BONE 37 Missense_Mutation SNP T C uc001gis.2 FASLG_uc001git.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 HOS_BONE 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FN1 2 216244182 216244185 HOS_BONE 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GHR 5 42719562 42719562 HOS_BONE 37 3'UTR SNP A T uc003jmt.2 GHR_uc011cpq.1_... Hybrid_Cap... view
GPR112 p.G713fs X 135428002 135428002 HOS_BONE 37 Frame_Shift_Del Del G - uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GUCY2C 12 14827464 14827466 HOS_BONE 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
IDH1 p.M259I 2 209106791 209106791 HOS_BONE 37 Missense_Mutation SNP C T uc002vcs.2 IDH1_uc002vct.2... Hybrid_Cap... view
KSR2 p.M896I 12 117907538 117907538 HOS_BONE 37 Missense_Mutation SNP C A uc001two.2 Hybrid_Cap... view
MAF 16 79628537 79628537 HOS_BONE 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 HOS_BONE 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K3 p.K183N 17 21206527 21206527 HOS_BONE 37 Missense_Mutation SNP G T uc002gys.2 MAP2K3_uc002gyt... Hybrid_Cap... view
MAP3K1 p.T949del 5 56177849 56177851 HOS_BONE 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.F600L 17 43348448 43348448 HOS_BONE 37 Missense_Mutation SNP A G uc002iiw.1 MAP3K14_uc002ii... Hybrid_Cap... view
MAP3K4 p.A1199del 6 161519351 161519353 HOS_BONE 37 In_Frame_Del Del CTG - uc003qtn.2 MAP3K4_uc010kkc... Hybrid_Cap...
MSH3 p.PPA66del 5 79950742 79950750 HOS_BONE 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MYST4 p.E1104del 10 76781906 76781908 HOS_BONE 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NCAM1 11 112832307 112832308 HOS_BONE 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 HOS_BONE 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 HOS_BONE 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NF1 p.V689M 17 29553516 29553516 HOS_BONE 37 Missense_Mutation SNP G A uc002hgg.2 NF1_uc002hgh.2_... Hybrid_Cap... view
NPAT p.K1418R 11 108029700 108029700 HOS_BONE 37 Missense_Mutation SNP T C uc001pjz.3 NPAT_uc010rvv.1... Hybrid_Cap... view
NPM1 5 170837734 170837734 HOS_BONE 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 HOS_BONE 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 HOS_BONE 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NSD1 p.H1096Y 5 176638686 176638686 HOS_BONE 37 Missense_Mutation SNP C T uc003mfr.3 NSD1_uc003mft.3... Hybrid_Cap... view
OR4E2 p.L66fs 14 22133493 22133493 HOS_BONE 37 Frame_Shift_Del Del T - uc010tmd.1 Hybrid_Cap...
PCM1 8 17813218 17813218 HOS_BONE 37 Intron Del T - uc003wyi.3 PCM1_uc011kyh.1... Hybrid_Cap...
PIK3R1 5 67584458 67584458 HOS_BONE 37 Intron SNP G T uc003jva.2 PIK3R1_uc003jvb... Hybrid_Cap... view
PKHD1 p.K2415R 6 51747997 51747997 HOS_BONE 37 Missense_Mutation SNP T C uc003pah.1 PKHD1_uc010jzn.... Hybrid_Cap... view
PLCB2 15 40600014 40600014 HOS_BONE 37 5'UTR SNP A T uc001zld.2 PLCB2_uc010bbo.... Hybrid_Cap... view
RPS6KC1 p.H143Q 1 213290709 213290709 HOS_BONE 37 Missense_Mutation SNP C G uc010ptr.1 RPS6KC1_uc001hk... Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 HOS_BONE 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
STK25 2 242435659 242435662 HOS_BONE 37 Intron Del AAGG - rs3215138;rs75497042 uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap...
STK31 7 23872024 23872025 HOS_BONE 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TEC 4 48139307 48139310 HOS_BONE 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TIAM1 p.H1010P 21 32526707 32526707 HOS_BONE 37 Missense_Mutation SNP T G uc002yow.1 TIAM1_uc011adk.... Hybrid_Cap... view
TMEM123 11 102269398 102269398 HOS_BONE 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNKS2 p.L730V 10 93605527 93605527 HOS_BONE 37 Missense_Mutation SNP C G uc001khp.2 Hybrid_Cap... view
TP53 p.R156P 17 7578463 7578463 HOS_BONE 37 Missense_Mutation SNP C G uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM33 1 114940215 114940216 HOS_BONE 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TTBK1 p.E771del 6 43250726 43250728 HOS_BONE 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
TTN 2 179391639 179391640 HOS_BONE 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.C15766R 2 179467129 179467129 HOS_BONE 37 Missense_Mutation SNP A G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.E10172del 2 179542390 179542392 HOS_BONE 37 In_Frame_Del Del CTT - uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TYRO3 15 41853706 41853706 HOS_BONE 37 Intron SNP C T uc001zof.1 TYRO3_uc001zoe.... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 HOS_BONE 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...