Annotation Summary for Cell Line: HPAF-II  

Cell line primary name: HPAF-II
Cell line aliases:
Gender: M
Site Primary: pancreas
Histology: carcinoma
Hist Subtype1: ductal_carcinoma
Notes:
Source: ATCC
Expression arrays: CASED_p_NCLE_RNA4_HG-U133_Plus_2_A06_383730
SNP arrays: FIEFS_p_NCLE_DNA_Affy5_GenomeWideSNP_6_C04_411050
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in HPAF-II

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 HPAFII_PANCREAS 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM17 2 9630245 9630245 HPAFII_PANCREAS 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 HPAFII_PANCREAS 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADCK1 14 78390632 78390637 HPAFII_PANCREAS 37 Intron Del AAACT... - rs78274857;rs74969652 uc001xui.2 ADCK1_uc010tvo.... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 HPAFII_PANCREAS 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 HPAFII_PANCREAS 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.1388_1389FF>F 18 56203253 56203255 HPAFII_PANCREAS 37 In_Frame_Del Del AAG - uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
BIRC6 p.E4123G 2 32768384 32768384 HPAFII_PANCREAS 37 Missense_Mutation SNP A G uc010ezu.2 Hybrid_Cap... view
BRD2 6 32948599 32948599 HPAFII_PANCREAS 37 3'UTR Del C - uc010juh.2 BRD2_uc003ocn.3... Hybrid_Cap...
CACNB2 10 18828721 18828722 HPAFII_PANCREAS 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDK11B 1 1654066 1654068 HPAFII_PANCREAS 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CDK17 12 96674483 96674483 HPAFII_PANCREAS 37 Intron SNP T C uc001tep.1 CDK17_uc009ztk.... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 HPAFII_PANCREAS 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CLTCL1 22 19196673 19196674 HPAFII_PANCREAS 37 Intron Ins - A uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CSNK1G2 19 1980210 1980210 HPAFII_PANCREAS 37 3'UTR SNP C T uc002lul.3 CSNK1G2_uc010ds... Hybrid_Cap... view
CYP1B1 2 38297654 38297655 HPAFII_PANCREAS 37 3'UTR Ins - A rs9341258 uc002rqo.2 Hybrid_Cap...
DDB2 11 47237767 47237767 HPAFII_PANCREAS 37 Intron SNP G A uc001neb.2 DDB2_uc001nec.2... Hybrid_Cap... view
DTX1 p.A214T 12 113515609 113515609 HPAFII_PANCREAS 37 Missense_Mutation SNP G A uc001tuk.1 Hybrid_Cap... view
EIF2AK2 2 37334185 37334186 HPAFII_PANCREAS 37 3'UTR Ins - A rs66470022 uc010ynh.1 EIF2AK2_uc010fa... Hybrid_Cap...
EPHA6 3 97367230 97367231 HPAFII_PANCREAS 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ETV1 7 14028708 14028708 HPAFII_PANCREAS 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGF20 p.Y210Y 8 16850587 16850587 HPAFII_PANCREAS 37 Silent SNP G A uc003wxc.1 FGF20_uc010lsv.... Hybrid_Cap... view
FGFR1OP p.D340E 6 167446122 167446122 HPAFII_PANCREAS 37 Missense_Mutation SNP T A uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap... view
FLI1 11 128638217 128638217 HPAFII_PANCREAS 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FMN2 p.G59del 1 240255569 240255571 HPAFII_PANCREAS 37 In_Frame_Del Del GGC - uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FZD1 p.93_94insP 7 90894459 90894460 HPAFII_PANCREAS 37 In_Frame_Ins Ins - CCG uc003ula.2 Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 HPAFII_PANCREAS 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 HPAFII_PANCREAS 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
HIF1A 14 62213929 62213930 HPAFII_PANCREAS 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
ILK 11 6630029 6630029 HPAFII_PANCREAS 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
JUND p.E291D 19 18391422 18391422 HPAFII_PANCREAS 37 Missense_Mutation SNP C A uc002nip.2 Hybrid_Cap... view
KALRN p.K1925M 3 124369767 124369767 HPAFII_PANCREAS 37 Missense_Mutation SNP A T uc003ehg.2 KALRN_uc003ehi.... Hybrid_Cap... view
KLK7 19 51480672 51480675 HPAFII_PANCREAS 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KRAS p.G12D 12 25398284 25398284 HPAFII_PANCREAS 37 Missense_Mutation SNP C T uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 HPAFII_PANCREAS 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 HPAFII_PANCREAS 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 HPAFII_PANCREAS 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPK10 4 86938306 86938306 HPAFII_PANCREAS 37 3'UTR SNP G C uc003hpq.2 MAPK10_uc010ikg... Hybrid_Cap... view
MAPK14 6 36076345 36076354 HPAFII_PANCREAS 37 3'UTR Del GTGTG... - rs80147786 uc003olp.2 MAPK14_uc003olq... Hybrid_Cap...
MAPKAPK3 3 50685575 50685575 HPAFII_PANCREAS 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MAST4 p.Q1695* 5 66460657 66460657 HPAFII_PANCREAS 37 Nonsense_Mutation SNP C T uc003jut.1 MAST4_uc003juw.... Hybrid_Cap... view
MLH1 p.S340S 3 37061936 37061936 HPAFII_PANCREAS 37 Silent SNP C G uc003cgl.2 MLH1_uc011aye.1... Hybrid_Cap... view
MLLT6 17 36881873 36881873 HPAFII_PANCREAS 37 3'UTR Del C - uc002hqi.3 MLLT6_uc002hqk.... Hybrid_Cap...
MSH3 p.PPA66del 5 79950742 79950750 HPAFII_PANCREAS 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MTMR11 1 149900985 149900986 HPAFII_PANCREAS 37 3'UTR Ins - A rs114426061 uc001etl.3 SF3B4_uc001etj.... Hybrid_Cap...
MYLK p.G1639R 3 123356964 123356964 HPAFII_PANCREAS 37 Missense_Mutation SNP C G uc003ego.2 MYLK_uc010hrr.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 HPAFII_PANCREAS 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 HPAFII_PANCREAS 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 HPAFII_PANCREAS 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 HPAFII_PANCREAS 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NOTCH4 p.16_16L>LL 6 32191658 32191659 HPAFII_PANCREAS 37 In_Frame_Ins Ins - AGC rs67287835 uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap...
NPM1 5 170837734 170837734 HPAFII_PANCREAS 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 HPAFII_PANCREAS 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP214 9 134067556 134067557 HPAFII_PANCREAS 37 Intron Ins - T rs66652901 uc004cag.2 NUP214_uc004cah... Hybrid_Cap...
PAX3 2 223158653 223158653 HPAFII_PANCREAS 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP p.Q1665fs 1 144873963 144873963 HPAFII_PANCREAS 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.V486fs 1 144917828 144917828 HPAFII_PANCREAS 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PGR 11 100933598 100933599 HPAFII_PANCREAS 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2G 12 18800990 18800990 HPAFII_PANCREAS 37 3'UTR Del A - rs16914368 uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PMS1 2 190670539 190670540 HPAFII_PANCREAS 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 HPAFII_PANCREAS 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG1 10 54053913 54053914 HPAFII_PANCREAS 37 3'UTR Ins - G rs35902208 uc001jjo.2 PRKG1_uc001jjm.... Hybrid_Cap...
RASGRF1 15 79277150 79277151 HPAFII_PANCREAS 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 HPAFII_PANCREAS 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RPS6KL1 14 75373626 75373627 HPAFII_PANCREAS 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
STAT1 2 191840353 191840353 HPAFII_PANCREAS 37 Intron Del T - uc002usj.2 STAT1_uc010fse.... Hybrid_Cap...
STK31 7 23872024 23872025 HPAFII_PANCREAS 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TGFBR1 p.N338S 9 101907053 101907053 HPAFII_PANCREAS 37 Missense_Mutation SNP A G uc004azc.2 TGFBR1_uc004azd... Hybrid_Cap... view
TNNI3K p.G395fs 1 74808813 74808813 HPAFII_PANCREAS 37 Frame_Shift_Del Del A - uc001dge.1 TNNI3K_uc001dgc... Hybrid_Cap...
TP53 p.P151S 17 7578479 7578479 HPAFII_PANCREAS 37 Missense_Mutation SNP G A rs28934874 uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189598036 189598036 HPAFII_PANCREAS 37 Intron SNP A G uc003fry.2 TP63_uc003frx.2... Hybrid_Cap... view
TTK p.L609F 6 80745035 80745035 HPAFII_PANCREAS 37 Missense_Mutation SNP C T uc003pjc.2 TTK_uc003pjb.3_... Hybrid_Cap... view
TTN p.E32948K 2 179393932 179393932 HPAFII_PANCREAS 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.N21688D 2 179438093 179438093 HPAFII_PANCREAS 37 Missense_Mutation SNP T C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 HPAFII_PANCREAS 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WDHD1 14 55408116 55408117 HPAFII_PANCREAS 37 3'UTR Del AT - uc001xbm.1 WDHD1_uc010aom.... Hybrid_Cap...
YSK4 p.K1264R 2 135738520 135738520 HPAFII_PANCREAS 37 Missense_Mutation SNP T C uc002tue.1 YSK4_uc002tuf.1... Hybrid_Cap... view