Annotation Summary for Cell Line: IA-LM  

Cell line primary name: IA-LM
Cell line aliases:
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: large_cell_carcinoma
Notes:
Source: RIKEN
Expression arrays: CASED_p_NCLE_RNA4_HG-U133_Plus_2_F11_383686
SNP arrays: PODIA_p_NCLE_DNAAffy7_GenomeWideSNP_6_A01_437562
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in IA-LM

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 IALM_LUNG 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM28 8 24211994 24211997 IALM_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS20 p.P28Q 12 43945641 43945642 IALM_LUNG 37 Missense_Mutation DNP GG TT uc010skx.1 Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 IALM_LUNG 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP6 p.N617I 14 33015709 33015709 IALM_LUNG 37 Missense_Mutation SNP A T uc001wrq.2 AKAP6_uc010aml.... Hybrid_Cap... view
ASPH p.A264_splice 8 62550924 62550925 IALM_LUNG 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
ASTN1 p.P29Q 1 177133727 177133727 IALM_LUNG 37 Missense_Mutation SNP G T uc001glc.2 ASTN1_uc001glb.... Hybrid_Cap... view
AURKC 19 57742494 57742507 IALM_LUNG 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
C9ORF96 p.L631P 9 136270394 136270394 IALM_LUNG 37 Missense_Mutation SNP T C uc004cdk.2 C9orf96_uc004cd... Hybrid_Cap... view
CACNA1F p.R83W X 49088168 49088168 IALM_LUNG 37 Missense_Mutation SNP G A uc004dnb.2 CACNA1F_uc010ni... Hybrid_Cap... view
CACNB2 10 18828721 18828722 IALM_LUNG 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CARD10 p.L426P 22 37902305 37902305 IALM_LUNG 37 Missense_Mutation SNP A G uc003asx.1 CARD10_uc003ast... Hybrid_Cap... view
CARD10 p.KE272del 22 37906309 37906314 IALM_LUNG 37 In_Frame_Del Del CTCCT... - uc003asx.1 CARD10_uc003ast... Hybrid_Cap...
CCNA2 p.V72_splice 4 122743803 122743804 IALM_LUNG 37 Splice_Site_Ins Ins - A uc003iec.3 Hybrid_Cap...
CCR6 6 167417454 167417454 IALM_LUNG 37 5'UTR SNP G A uc003qvl.2 FGFR1OP_uc011eg... Hybrid_Cap... view
CDKN2A p.R156L 9 21971057 21971057 IALM_LUNG 37 Missense_Mutation SNP C A rs104894094 uc003zpl.2 MTAP_uc003zpi.1... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 IALM_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
COL3A1 2 189876522 189876522 IALM_LUNG 37 3'UTR SNP C T uc002uqj.1 Hybrid_Cap... view
CSMD3 p.L2017I 8 113392668 113392668 IALM_LUNG 37 Missense_Mutation SNP G T uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CTSS 1 150705407 150705407 IALM_LUNG 37 3'UTR SNP T C uc001evn.2 CTSS_uc010pcj.1... Hybrid_Cap... view
DBN1 p.E235K 5 176893922 176893922 IALM_LUNG 37 Missense_Mutation SNP C T uc003mgx.2 DBN1_uc003mgy.2... Hybrid_Cap... view
DDX1 p.G209_splice 2 15744634 15744634 IALM_LUNG 37 Splice_Site_SNP SNP G T uc002rce.2 DDX1_uc010yjq.1... Hybrid_Cap... view
DGKB 7 14216345 14216346 IALM_LUNG 37 Intron Ins - AGACT uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap...
DGKG p.R296H 3 185993359 185993359 IALM_LUNG 37 Missense_Mutation SNP C T uc003fqa.2 DGKG_uc003fqb.2... Hybrid_Cap... view
DOCK3 p.I1525L 3 51394462 51394462 IALM_LUNG 37 Missense_Mutation SNP A C uc011bds.1 Hybrid_Cap... view
DST 6 56707987 56707987 IALM_LUNG 37 Intron SNP C T uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
EDN1 6 12290729 12290729 IALM_LUNG 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EPHA4 2 222290623 222290624 IALM_LUNG 37 3'UTR Ins - T uc002vmq.2 EPHA4_uc002vmr.... Hybrid_Cap...
EPHA5 p.C815F 4 66217174 66217174 IALM_LUNG 37 Missense_Mutation SNP C A uc011cah.1 EPHA5_uc003hcx.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 IALM_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
FER p.P551T 5 108295043 108295043 IALM_LUNG 37 Missense_Mutation SNP C A uc003kop.1 FER_uc011cvf.1_... Hybrid_Cap... view
FLNA X 153577132 153577133 IALM_LUNG 37 3'UTR Ins - CA rs10692455;rs71733538 uc004fkk.2 FLNA_uc004fki.2... Hybrid_Cap...
FOXP1 3 71008341 71008342 IALM_LUNG 37 3'UTR Ins - T rs11433724;rs114233617 uc003dol.2 FOXP1_uc003dom.... Hybrid_Cap...
FRAT1 10 99080112 99080112 IALM_LUNG 37 3'UTR SNP T C uc001knc.1 Hybrid_Cap... view
GAB1 p.L270S 4 144359367 144359367 IALM_LUNG 37 Missense_Mutation SNP T C uc003ijd.2 GAB1_uc003ije.2... Hybrid_Cap... view
GNAQ p.I217L 9 80409465 80409465 IALM_LUNG 37 Missense_Mutation SNP T A uc004akw.2 GNAQ_uc011lso.1... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 IALM_LUNG 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 IALM_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIK1 p.D163Y 21 31062105 31062105 IALM_LUNG 37 Missense_Mutation SNP C A uc011acs.1 GRIK1_uc002ynn.... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 IALM_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HOXD10 2 176984021 176984021 IALM_LUNG 37 3'UTR SNP G T uc002ukj.2 Hybrid_Cap... view
ILK 11 6630029 6630029 IALM_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INPP5D p.R982Q 2 234106992 234106992 IALM_LUNG 37 Missense_Mutation SNP G A uc010zmo.1 INPP5D_uc010zmp... Hybrid_Cap... view
ITGB8 p.A405S 7 20438548 20438549 IALM_LUNG 37 Missense_Mutation DNP CG GT uc003suu.2 ITGB8_uc011jyh.... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 IALM_LUNG 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KDR p.T1339I 4 55946163 55946163 IALM_LUNG 37 Missense_Mutation SNP G A uc003has.2 KDR_uc003hat.1_... Hybrid_Cap... view
KIAA1549 p.D1428V 7 138564346 138564346 IALM_LUNG 37 Missense_Mutation SNP T A uc011kql.1 KIAA1549_uc011k... Hybrid_Cap... view
KRAS p.G12C 12 25398285 25398285 IALM_LUNG 37 Missense_Mutation SNP C A uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
LATS1 p.P237Q 6 150005515 150005515 IALM_LUNG 37 Missense_Mutation SNP G T rs56149740 uc003qmu.1 LATS1_uc010kif.... Hybrid_Cap... view
LATS2 13 21620222 21620223 IALM_LUNG 37 5'UTR Ins - A rs61240127;rs115723063 uc009zzs.2 LATS2_uc001unr.... Hybrid_Cap...
LRP1B p.R531H 2 141806752 141806752 IALM_LUNG 37 Missense_Mutation SNP C T uc002tvj.1 LRP1B_uc010fnl.... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 IALM_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 IALM_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 IALM_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MEF2A p.QQ428del 15 100252710 100252715 IALM_LUNG 37 In_Frame_Del Del CAGCA... - uc010urw.1 MEF2A_uc010urv.... Hybrid_Cap...
MLL3 p.P4033L 7 151851393 151851393 IALM_LUNG 37 Missense_Mutation SNP G A uc003wla.2 MLL3_uc003wkz.2... Hybrid_Cap... view
MLL3 p.D1451Y 7 151893019 151893019 IALM_LUNG 37 Missense_Mutation SNP C A uc003wla.2 MLL3_uc003wkz.2... Hybrid_Cap... view
MSH3 p.AAA58del 5 79950709 79950717 IALM_LUNG 37 In_Frame_Del Del GCAGC... - rs67658031;rs2431220 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MYST3 p.E1109del 8 41794797 41794799 IALM_LUNG 37 In_Frame_Del Del TCT - uc010lxb.2 MYST3_uc010lxc.... Hybrid_Cap...
NCAM1 11 112832307 112832308 IALM_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 IALM_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK1 p.R721W 4 170398627 170398627 IALM_LUNG 37 Missense_Mutation SNP G A uc003isd.1 NEK1_uc003isb.1... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 IALM_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NEK5 p.D515N 13 52657425 52657425 IALM_LUNG 37 Missense_Mutation SNP C T uc001vge.2 Hybrid_Cap... view
NFKBIA 14 35871136 35871138 IALM_LUNG 37 3'UTR Del TTC - rs112369437 uc001wtf.3 NFKBIA_uc001wte... Hybrid_Cap...
NOS2 p.Q310K 17 26107869 26107869 IALM_LUNG 37 Missense_Mutation SNP G T uc002gzu.2 NOS2_uc010crh.1... Hybrid_Cap... view
NPR1 1 153665919 153665920 IALM_LUNG 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 IALM_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NTRK2 p.W230L 9 87338593 87338593 IALM_LUNG 37 Missense_Mutation SNP G T uc004anz.1 NTRK2_uc004anv.... Hybrid_Cap... view
NUP153 p.S1050F 6 17629374 17629374 IALM_LUNG 37 Missense_Mutation SNP G A uc011dje.1 NUP153_uc003ncd... Hybrid_Cap... view
NUP98 p.M192V 11 3794891 3794891 IALM_LUNG 37 Missense_Mutation SNP T C uc001lyh.2 NUP98_uc001lyi.... Hybrid_Cap... view
OR2L13 p.S290I 1 248263546 248263546 IALM_LUNG 37 Missense_Mutation SNP G T uc001ids.2 Hybrid_Cap... view
PAX3 2 223066017 223066018 IALM_LUNG 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 IALM_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX5 9 37034093 37034095 IALM_LUNG 37 5'UTR Del TTC - uc003zzo.1 PAX5_uc011lpw.1... Hybrid_Cap...
PDGFRA p.N232S 4 54257655 54257655 IALM_LUNG 37 Missense_Mutation SNP A G uc003haa.2 FIP1L1_uc003gzx... Hybrid_Cap... view
PDK1 2 173460743 173460743 IALM_LUNG 37 3'UTR SNP A G rs70937078 uc002uhq.1 PDK1_uc010zdz.1... Hybrid_Cap... view
PHF3 p.E1774K 6 64422804 64422804 IALM_LUNG 37 Missense_Mutation SNP G A uc003pep.1 PHF3_uc003pen.2... Hybrid_Cap... view
PHIP 6 79650265 79650266 IALM_LUNG 37 3'UTR Ins - TTTT rs70977753;rs13191571 uc003pir.2 PHIP_uc003piq.2... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 IALM_LUNG 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3C2G 12 18800990 18800990 IALM_LUNG 37 3'UTR Del A - rs16914368 uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PKHD1 p.G565_splice 6 51920528 51920528 IALM_LUNG 37 Splice_Site_SNP SNP C T uc003pah.1 PKHD1_uc003pai.... Hybrid_Cap... view
PMS1 2 190670539 190670540 IALM_LUNG 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PRAME p.Q428* 22 22890737 22890737 IALM_LUNG 37 Nonsense_Mutation SNP G A uc002zwf.2 LOC96610_uc011a... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 IALM_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 IALM_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RECQL4 p.R347H 8 145741463 145741463 IALM_LUNG 37 Missense_Mutation SNP C T uc003zdj.2 LRRC14_uc003zdk... Hybrid_Cap... view
RIMS2 p.R102M 8 104897798 104897798 IALM_LUNG 37 Missense_Mutation SNP G T uc003yls.2 RIMS2_uc003ylp.... Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 IALM_LUNG 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SCRIB p.S962F 8 144886862 144886862 IALM_LUNG 37 Missense_Mutation SNP G A uc003yzo.1 SCRIB_uc003yzn.... Hybrid_Cap... view
SEPT6 X 118752786 118752786 IALM_LUNG 37 3'UTR SNP C G uc004eru.2 SEPT6_uc010nqk.... Hybrid_Cap... view
SEPT9 17 75494787 75494788 IALM_LUNG 37 3'UTR Ins - C rs5822173 uc002jts.3 SEPT9_uc010wtk.... Hybrid_Cap...
SFPQ p.D455E 1 35656149 35656149 IALM_LUNG 37 Missense_Mutation SNP A T uc001bys.2 SFPQ_uc001byr.2... Hybrid_Cap... view
SIX4 p.Q673* 14 61180454 61180454 IALM_LUNG 37 Nonsense_Mutation SNP G A uc001xfc.2 Hybrid_Cap... view
SPEN p.H717R 1 16254885 16254885 IALM_LUNG 37 Missense_Mutation SNP A G uc001axk.1 SPEN_uc010obp.1... Hybrid_Cap... view
STAC2 17 37368326 37368326 IALM_LUNG 37 3'UTR SNP T C uc002hrs.2 STAC2_uc010cvt.... Hybrid_Cap... view
STK31 7 23872024 23872025 IALM_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TGFB2 1 218519928 218519929 IALM_LUNG 37 5'UTR Ins - AAAC uc001hln.2 TGFB2_uc001hll.... Hybrid_Cap...
TLR4 p.L7M 9 120466768 120466769 IALM_LUNG 37 Missense_Mutation DNP CC AA uc004bjz.2 TLR4_uc004bka.2... Hybrid_Cap...
TMEM123 11 102269398 102269398 IALM_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNFRSF8 p.R210S 1 12170215 12170215 IALM_LUNG 37 Missense_Mutation SNP G T uc001atq.2 TNFRSF8_uc010ob... Hybrid_Cap... view
TNK2 p.R445W 3 195605334 195605334 IALM_LUNG 37 Missense_Mutation SNP G A uc003fvt.1 TNK2_uc003fvs.1... Hybrid_Cap... view
TP53 p.Q192* 17 7578275 7578275 IALM_LUNG 37 Nonsense_Mutation SNP G A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 IALM_LUNG 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRPS1 8 116635872 116635873 IALM_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN 2 179391639 179391640 IALM_LUNG 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.R19752H 2 179445147 179445147 IALM_LUNG 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.P19196H 2 179448618 179448618 IALM_LUNG 37 Missense_Mutation SNP G T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.P10772S 2 179515979 179515979 IALM_LUNG 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 IALM_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WEE2 p.T83I 7 141408806 141408806 IALM_LUNG 37 Missense_Mutation SNP C T uc003vwn.2 FLJ40852_uc011k... Hybrid_Cap... view