Annotation Summary for Cell Line: IST-MES1  

Cell line primary name: IST-MES1
Cell line aliases:
Gender: F
Site Primary: pleura
Histology: mesothelioma
Hist Subtype1: NS
Notes:
Source: ICLC
Expression arrays: AGENT_p_NCLE_RNA6_HG-U133_Plus_2_G09_436490
SNP arrays: BOWER_p_NCLE_DNAAffy8_GenomeWideSNP_6_G11_464660
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in IST-MES1

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 ISTMES1_PLEURA 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ABL2 1 179086419 179086420 ISTMES1_PLEURA 37 Intron Ins - A rs72207641 uc001gmj.3 ABL2_uc010pnf.1... Hybrid_Cap...
ACACB p.Q572R 12 109617789 109617789 ISTMES1_PLEURA 37 Missense_Mutation SNP A G uc001tob.2 ACACB_uc001toc.... Hybrid_Cap... view
ADAM28 8 24211994 24211997 ISTMES1_PLEURA 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADCK1 14 78390632 78390637 ISTMES1_PLEURA 37 Intron Del AAACT... - rs78274857;rs74969652 uc001xui.2 ADCK1_uc010tvo.... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 ISTMES1_PLEURA 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 ISTMES1_PLEURA 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ALPK2 p.S171T 18 56247497 56247497 ISTMES1_PLEURA 37 Missense_Mutation SNP A T uc002lhj.3 Hybrid_Cap... view
ALPK2 p.A89G 18 56247742 56247742 ISTMES1_PLEURA 37 Missense_Mutation SNP G C uc002lhj.3 Hybrid_Cap... view
AMZ2 17 66246265 66246265 ISTMES1_PLEURA 37 Intron SNP G A uc002jgs.1 AMZ2_uc002jgr.1... Hybrid_Cap... view
BAP1 p.K661_splice 3 52436788 52436794 ISTMES1_PLEURA 37 Splice_Site_Del Del CACCC... - uc003ddx.2 BAP1_uc003ddw.2... Hybrid_Cap...
BMP4 14 54416601 54416602 ISTMES1_PLEURA 37 3'UTR Ins - AT rs74495140;rs76335800 uc001xal.3 BMP4_uc010aoh.2... Hybrid_Cap...
CD79A 19 42385075 42385075 ISTMES1_PLEURA 37 3'UTR SNP G A uc002orv.2 CD79A_uc002oru.... Hybrid_Cap... view
CDK10 16 89760066 89760066 ISTMES1_PLEURA 37 Intron SNP C T uc010cio.2 CDK10_uc010cip.... Hybrid_Cap... view
CLPTM1 p.I425T 19 45493794 45493794 ISTMES1_PLEURA 37 Missense_Mutation SNP T C uc002pai.2 CLPTM1_uc010xxf... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 ISTMES1_PLEURA 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CSNK1G2 19 1980472 1980473 ISTMES1_PLEURA 37 3'UTR Ins - A uc002lul.3 CSNK1G2_uc010ds... Hybrid_Cap...
CYP2B6 p.S259R 19 41515255 41515255 ISTMES1_PLEURA 37 Missense_Mutation SNP C A rs45482602 uc002opr.1 CYP2A7_uc002opo... Hybrid_Cap... view
DAB1 p.T389A 1 57480835 57480835 ISTMES1_PLEURA 37 Missense_Mutation SNP T C uc001cys.1 DAB1_uc001cyt.1... Hybrid_Cap... view
DNAH8 p.R2807* 6 38867558 38867558 ISTMES1_PLEURA 37 Nonsense_Mutation SNP C T uc003ooe.1 Hybrid_Cap... view
DYRK1A 21 38884966 38884967 ISTMES1_PLEURA 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EDN1 6 12290729 12290729 ISTMES1_PLEURA 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EGF 4 110834409 110834409 ISTMES1_PLEURA 37 5'UTR SNP G A uc003hzy.3 EGF_uc011cfu.1_... Hybrid_Cap... view
EPHA6 3 97367230 97367231 ISTMES1_PLEURA 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPS15 1 51822219 51822220 ISTMES1_PLEURA 37 3'UTR Ins - A rs111272942 uc001csq.1 EPS15_uc009vyz.... Hybrid_Cap...
FAM118A p.R126W 22 45723798 45723798 ISTMES1_PLEURA 37 Missense_Mutation SNP C T uc003bfz.3 FAM118A_uc003bg... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 ISTMES1_PLEURA 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 ISTMES1_PLEURA 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 ISTMES1_PLEURA 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FN1 2 216244182 216244185 ISTMES1_PLEURA 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FOXO3 p.P292S 6 108984910 108984910 ISTMES1_PLEURA 37 Missense_Mutation SNP C T uc003psk.2 FOXO3_uc003psn.... Hybrid_Cap... view
FZD1 p.93_94insP 7 90894459 90894460 ISTMES1_PLEURA 37 In_Frame_Ins Ins - CCG uc003ula.2 Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 ISTMES1_PLEURA 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 ISTMES1_PLEURA 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
HNF1A 12 121434630 121434631 ISTMES1_PLEURA 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
IGF1R 15 99192755 99192763 ISTMES1_PLEURA 37 5'UTR Del TTTTT... - uc002bul.2 IGF1R_uc010urq.... Hybrid_Cap...
ILK 11 6630029 6630029 ISTMES1_PLEURA 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INHBA 7 41729111 41729112 ISTMES1_PLEURA 37 3'UTR Ins - T rs116913029 uc003thq.2 INHBA_uc003thr.... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 ISTMES1_PLEURA 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KIAA1549 p.R1480W 7 138556016 138556016 ISTMES1_PLEURA 37 Missense_Mutation SNP G A uc011kql.1 KIAA1549_uc011k... Hybrid_Cap... view
KLK7 19 51480672 51480675 ISTMES1_PLEURA 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LAMA1 p.C2297S 18 6971865 6971865 ISTMES1_PLEURA 37 Missense_Mutation SNP C G uc002knm.2 LAMA1_uc010wzj.... Hybrid_Cap... view
MAF 16 79628537 79628537 ISTMES1_PLEURA 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAF 16 79628325 79628325 ISTMES1_PLEURA 37 3'UTR Del A - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 ISTMES1_PLEURA 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 ISTMES1_PLEURA 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 ISTMES1_PLEURA 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K4 p.A1199del 6 161519351 161519353 ISTMES1_PLEURA 37 In_Frame_Del Del CTG - uc003qtn.2 MAP3K4_uc010kkc... Hybrid_Cap...
MAPKAPK2 p.E162A 1 206902741 206902741 ISTMES1_PLEURA 37 Missense_Mutation SNP A C uc001hem.1 MAPKAPK2_uc001h... Hybrid_Cap... view
MELK 9 36677357 36677357 ISTMES1_PLEURA 37 3'UTR SNP C T uc003zzn.2 MELK_uc011lpm.1... Hybrid_Cap... view
MLL3 p.Y816fs 7 151945071 151945072 ISTMES1_PLEURA 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
MLLT6 17 36881873 36881873 ISTMES1_PLEURA 37 3'UTR Del C - uc002hqi.3 MLLT6_uc002hqk.... Hybrid_Cap...
MYH11 p.K1406K 16 15818186 15818186 ISTMES1_PLEURA 37 Silent SNP C T rs113302393 uc002ddx.2 MYH11_uc002ddv.... Hybrid_Cap... view
MYLK 3 123332876 123332876 ISTMES1_PLEURA 37 3'UTR Del T - rs115544676 uc003ego.2 MYLK_uc003egl.2... Hybrid_Cap...
MYLK p.E1430_splice 3 123368043 123368044 ISTMES1_PLEURA 37 Splice_Site_Ins Ins - G rs41431347 uc003ego.2 MYLK_uc010hrr.2... Hybrid_Cap...
N4BP2 p.L37L 4 40099071 40099071 ISTMES1_PLEURA 37 Silent SNP A G uc003guy.3 N4BP2_uc010ifq.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 ISTMES1_PLEURA 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 ISTMES1_PLEURA 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NDE1 16 15818428 15818428 ISTMES1_PLEURA 37 3'UTR SNP C T uc010uzy.1 MYH11_uc002ddv.... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 ISTMES1_PLEURA 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 ISTMES1_PLEURA 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NOTCH4 p.15_16LL>L 6 32191659 32191661 ISTMES1_PLEURA 37 In_Frame_Del Del AGC - uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap...
NPR1 1 153665919 153665920 ISTMES1_PLEURA 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 ISTMES1_PLEURA 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 ISTMES1_PLEURA 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUAK2 1 205290814 205290814 ISTMES1_PLEURA 37 5'UTR SNP T C uc001hce.2 Hybrid_Cap... view
ODZ1 p.L1803fs X 123526173 123526183 ISTMES1_PLEURA 37 Frame_Shift_Del Del ATGGA... - uc010nqy.2 ODZ1_uc011muj.1... Hybrid_Cap...
PAX3 2 223066017 223066018 ISTMES1_PLEURA 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 ISTMES1_PLEURA 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PHIP 6 79650265 79650266 ISTMES1_PLEURA 37 3'UTR Ins - TT rs70977753;rs13191571 uc003pir.2 PHIP_uc003piq.2... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 ISTMES1_PLEURA 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIP4K2B 17 36955727 36955727 ISTMES1_PLEURA 37 5'UTR SNP G A uc002hqs.2 PIP4K2B_uc010wd... Hybrid_Cap... view
PKHD1 p.S3911Y 6 51491848 51491848 ISTMES1_PLEURA 37 Missense_Mutation SNP G T uc003pah.1 Hybrid_Cap... view
PMS1 2 190670539 190670540 ISTMES1_PLEURA 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 ISTMES1_PLEURA 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTPRU p.V610M 1 29606613 29606613 ISTMES1_PLEURA 37 Missense_Mutation SNP G A uc001bru.2 PTPRU_uc001brv.... Hybrid_Cap... view
RBPJ 4 26431822 26431822 ISTMES1_PLEURA 37 Intron Del A - rs76214390 uc003grx.1 RBPJ_uc003gry.1... Hybrid_Cap...
RFC4 p.R102* 3 186512553 186512553 ISTMES1_PLEURA 37 Nonsense_Mutation SNP G A uc003fqz.2 RFC4_uc011bsc.1... Hybrid_Cap... view
ROBO2 3 77666937 77666937 ISTMES1_PLEURA 37 Intron Del A - rs78745603 uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap...
RPS6KB1 17 58024224 58024225 ISTMES1_PLEURA 37 3'UTR Ins - AA rs67846207 uc002ixy.2 RPS6KB1_uc010dd... Hybrid_Cap...
RPS6KL1 14 75373626 75373627 ISTMES1_PLEURA 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
STK25 2 242435659 242435662 ISTMES1_PLEURA 37 Intron Del AAGG - rs3215138;rs75497042 uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap...
STK31 7 23872024 23872025 ISTMES1_PLEURA 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TACC3 4 1739519 1739527 ISTMES1_PLEURA 37 Intron Del GCCAT... - rs114226356 uc003gdo.2 TACC3_uc010ibz.... Hybrid_Cap...
TLK1 2 171850178 171850179 ISTMES1_PLEURA 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TMEM123 11 102269398 102269398 ISTMES1_PLEURA 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNNI3K p.R592H 1 74834948 74834948 ISTMES1_PLEURA 37 Missense_Mutation SNP G A uc001dge.1 TNNI3K_uc001dgc... Hybrid_Cap... view
TNRC6B p.Q1328del 22 40697177 40697179 ISTMES1_PLEURA 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TP63 3 189507518 189507519 ISTMES1_PLEURA 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIM33 1 114940215 114940216 ISTMES1_PLEURA 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TTN 2 179391639 179391640 ISTMES1_PLEURA 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 ISTMES1_PLEURA 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
ZAP70 2 98350147 98350147 ISTMES1_PLEURA 37 Intron SNP C T uc002syd.1 ZAP70_uc010yvf.... Hybrid_Cap... view
ZNF608 p.N671H 5 123984066 123984066 ISTMES1_PLEURA 37 Missense_Mutation SNP T G uc003ktq.1 ZNF608_uc003ktr... Hybrid_Cap... view