Annotation Summary for Cell Line: JHH-4  

Cell line primary name: JHH-4
Cell line aliases:
Gender: M
Site Primary: liver
Histology: carcinoma
Hist Subtype1: hepatocellular_carcinoma
Notes:
Source: HSRRB
Expression arrays: BRAKE_p_NCLE_RNA2_HG-U133_Plus_2_C01_241090
SNP arrays: ARLES_p_NCLE_DNAAffy2_S_GenomeWideSNP_6_E02_256100
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in JHH-4

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 JHH4_LIVER 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACVR1C 2 158390344 158390344 JHH4_LIVER 37 3'UTR Del A - uc002tzk.3 ACVR1C_uc002tzl... Hybrid_Cap...
ACVR2A p.C78* 2 148654048 148654048 JHH4_LIVER 37 Nonsense_Mutation SNP T A uc002twg.2 ACVR2A_uc010zbn... Hybrid_Cap... view
ADAM28 p.F156L 8 24170983 24170983 JHH4_LIVER 37 Missense_Mutation SNP T C uc003xdy.2 ADAM28_uc003xdx... Hybrid_Cap... view
ADAM28 8 24211994 24211997 JHH4_LIVER 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AFF4 p.K40R 5 132272763 132272763 JHH4_LIVER 37 Missense_Mutation SNP T C uc003kyd.2 AFF4_uc011cxk.1... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 JHH4_LIVER 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ANAPC5 12 121768483 121768483 JHH4_LIVER 37 Intron SNP G C uc001uag.2 ANAPC5_uc010szu... Hybrid_Cap... view
AR p.K610R X 66905912 66905912 JHH4_LIVER 37 Missense_Mutation SNP A G uc004dwu.1 AR_uc011mpd.1_M... Hybrid_Cap... view
AURKC 19 57742531 57742532 JHH4_LIVER 37 5'UTR Ins - C uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
CACNB2 10 18629707 18629707 JHH4_LIVER 37 Intron SNP T C uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap... view
CACNB2 10 18828721 18828722 JHH4_LIVER 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDK11A p.P575T 1 1635549 1635549 JHH4_LIVER 37 Missense_Mutation SNP G T uc009vks.2 CDK11B_uc001ags... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 JHH4_LIVER 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 JHH4_LIVER 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
DACH1 13 72014625 72014626 JHH4_LIVER 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DGKB 7 14216345 14216346 JHH4_LIVER 37 Intron Ins - AGACT uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap...
DLL4 p.R558* 15 41228857 41228857 JHH4_LIVER 37 Nonsense_Mutation SNP C T rs61750844 uc001zng.1 Hybrid_Cap... view
EGF p.E1134fs 4 110932389 110932390 JHH4_LIVER 37 Frame_Shift_Ins Ins - C rs11569144 uc003hzy.3 EGF_uc011cfu.1_... Hybrid_Cap...
EIF3A p.V1330F 10 120795712 120795712 JHH4_LIVER 37 Missense_Mutation SNP C A uc001ldu.2 EIF3A_uc010qsu.... Hybrid_Cap... view
EPHA3 p.R305K 3 89390165 89390165 JHH4_LIVER 37 Missense_Mutation SNP G A uc003dqy.2 EPHA3_uc003dqx.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 JHH4_LIVER 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 JHH4_LIVER 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 JHH4_LIVER 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 JHH4_LIVER 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 JHH4_LIVER 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FNBP1 p.D101G 9 132740787 132740787 JHH4_LIVER 37 Missense_Mutation SNP T C uc004byw.1 FNBP1_uc011mbv.... Hybrid_Cap... view
FOXP1 3 71008341 71008342 JHH4_LIVER 37 3'UTR Ins - T rs11433724;rs114233617 uc003dol.2 FOXP1_uc003dom.... Hybrid_Cap...
GPR137 11 64037873 64037873 JHH4_LIVER 37 5'UTR SNP A T uc009ypj.1 BAD_uc001nzd.2_... Hybrid_Cap... view
GRIA3 X 122318386 122318387 JHH4_LIVER 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 JHH4_LIVER 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 JHH4_LIVER 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HSP90B1 p.E791del 12 104341188 104341190 JHH4_LIVER 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 JHH4_LIVER 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INHBA 7 41740067 41740068 JHH4_LIVER 37 5'UTR Ins - T rs116230303 uc003thq.2 LOC285954_uc003... Hybrid_Cap...
IRAK2 p.R504Q 3 10280469 10280469 JHH4_LIVER 37 Missense_Mutation SNP G A uc003bve.1 Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 JHH4_LIVER 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KIAA0802 p.R1315Q 18 8825452 8825452 JHH4_LIVER 37 Missense_Mutation SNP G A uc002knr.2 KIAA0802_uc002k... Hybrid_Cap... view
KLK3 19 51363290 51363290 JHH4_LIVER 37 3'UTR SNP T C uc002pts.1 KLK3_uc010ycj.1... Hybrid_Cap... view
KLK7 19 51480672 51480675 JHH4_LIVER 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LAMA1 p.D1086N 18 7013921 7013921 JHH4_LIVER 37 Missense_Mutation SNP C T uc002knm.2 LAMA1_uc010wzj.... Hybrid_Cap... view
LAMA1 p.G919R 18 7017330 7017330 JHH4_LIVER 37 Missense_Mutation SNP C G uc002knm.2 LAMA1_uc010wzj.... Hybrid_Cap... view
LATS2 13 21620222 21620223 JHH4_LIVER 37 5'UTR Ins - A rs61240127;rs115723063 uc009zzs.2 LATS2_uc001unr.... Hybrid_Cap...
LMNA 1 156106567 156106567 JHH4_LIVER 37 Intron SNP C T uc001fni.2 LMNA_uc001fnf.1... Hybrid_Cap... view
MAF 16 79628537 79628537 JHH4_LIVER 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 JHH4_LIVER 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K1 15 66679649 66679650 JHH4_LIVER 37 5'UTR Ins - C rs67229745 uc010bhq.2 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 JHH4_LIVER 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP4K3 p.N321N 2 39542485 39542485 JHH4_LIVER 37 Silent SNP G A uc002rro.2 MAP4K3_uc002rrp... Hybrid_Cap... view
MAPKBP1 15 42111753 42111754 JHH4_LIVER 37 Intron Ins - C rs3034891 uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap...
MECOM 3 169381200 169381201 JHH4_LIVER 37 5'UTR Ins - T uc011bpj.1 MECOM_uc011bpk.... Hybrid_Cap...
MYLK 3 123332876 123332876 JHH4_LIVER 37 3'UTR Del T - rs115544676 uc003ego.2 MYLK_uc003egl.2... Hybrid_Cap...
MYO3A p.H442N 10 26359295 26359295 JHH4_LIVER 37 Missense_Mutation SNP C A uc001isn.2 MYO3A_uc009xko.... Hybrid_Cap... view
MYST3 p.E1109del 8 41794797 41794799 JHH4_LIVER 37 In_Frame_Del Del TCT - uc010lxb.2 MYST3_uc010lxc.... Hybrid_Cap...
NCAM1 11 112832307 112832308 JHH4_LIVER 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 JHH4_LIVER 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NFATC1 p.S675G 18 77227513 77227513 JHH4_LIVER 37 Missense_Mutation SNP A G uc010xfg.1 NFATC1_uc002lnc... Hybrid_Cap... view
NPR1 1 153665919 153665920 JHH4_LIVER 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NPRL2 3 50384978 50384978 JHH4_LIVER 37 3'UTR Del C - rs75013672 uc003daj.1 ZMYND10_uc003da... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 JHH4_LIVER 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
OBSCN p.A1693V 1 228456447 228456447 JHH4_LIVER 37 Missense_Mutation SNP C T uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
OR2L13 p.A172T 1 248263191 248263191 JHH4_LIVER 37 Missense_Mutation SNP G A uc001ids.2 Hybrid_Cap... view
PAPPA p.T1585I 9 119144750 119144750 JHH4_LIVER 37 Missense_Mutation SNP C T uc004bjn.2 PAPPA_uc011lxq.... Hybrid_Cap... view
PAX3 2 223066017 223066018 JHH4_LIVER 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 JHH4_LIVER 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PCDH15 p.P320L 10 55996624 55996624 JHH4_LIVER 37 Missense_Mutation SNP G A uc010qhy.1 PCDH15_uc010qhq... Hybrid_Cap... view
PDE4DIP p.L601fs 1 144915624 144915624 JHH4_LIVER 37 Frame_Shift_Del Del G - rs1778112 uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.E243fs 1 144923729 144923729 JHH4_LIVER 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDGFRA 4 55130162 55130162 JHH4_LIVER 37 Intron Del T - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PGGT1B 5 114548071 114548072 JHH4_LIVER 37 3'UTR Ins - C uc003kqw.3 PGGT1B_uc003kqx... Hybrid_Cap...
PIP5K1C p.R367H 19 3651851 3651851 JHH4_LIVER 37 Missense_Mutation SNP C T rs115799086 uc010xhr.1 PIP5K1C_uc002ly... Hybrid_Cap... view
PKHD1 p.A3030P 6 51613326 51613326 JHH4_LIVER 37 Missense_Mutation SNP C G uc003pah.1 PKHD1_uc010jzn.... Hybrid_Cap... view
PREX2 8 69143713 69143714 JHH4_LIVER 37 3'UTR Del TT - uc003xxv.1 Hybrid_Cap...
PRKCA 17 64298959 64298960 JHH4_LIVER 37 5'UTR Ins - G rs71160558 uc002jfp.1 PRKCA_uc002jfo.... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 JHH4_LIVER 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTPRC 1 198608375 198608375 JHH4_LIVER 37 5'UTR SNP T C uc001gur.1 PTPRC_uc001gus.... Hybrid_Cap... view
RANBP17 5 170338272 170338272 JHH4_LIVER 37 Intron SNP C G uc003mba.2 RANBP17_uc003ma... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 JHH4_LIVER 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROBO2 3 77666937 77666937 JHH4_LIVER 37 Intron Del A - rs78745603 uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap...
RPN1 p.V548M 3 128339436 128339436 JHH4_LIVER 37 Missense_Mutation SNP C T uc003ekr.1 RPN1_uc011bkq.1... Hybrid_Cap... view
RPS6KC1 p.K747R 1 213415059 213415059 JHH4_LIVER 37 Missense_Mutation SNP A G uc010ptr.1 RPS6KC1_uc001hk... Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 JHH4_LIVER 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SMG1 p.Q1309* 16 18870906 18870906 JHH4_LIVER 37 Nonsense_Mutation SNP G A uc002dfm.2 SMG1_uc010bwb.2... Hybrid_Cap... view
SMO p.K575M 7 128850877 128850877 JHH4_LIVER 37 Missense_Mutation SNP A T rs56383695 uc003vor.2 SMO_uc003vos.2_... Hybrid_Cap... view
SPEN p.V2683M 1 16260782 16260782 JHH4_LIVER 37 Missense_Mutation SNP G A uc001axk.1 SPEN_uc010obp.1... Hybrid_Cap... view
STK25 2 242435659 242435662 JHH4_LIVER 37 Intron Del AAGG - rs3215138;rs75497042 uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap...
STK31 7 23872024 23872025 JHH4_LIVER 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TACC3 4 1739519 1739527 JHH4_LIVER 37 Intron Del GCCAT... - rs114226356 uc003gdo.2 TACC3_uc010ibz.... Hybrid_Cap...
TEC 4 48139307 48139310 JHH4_LIVER 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TMEM123 11 102269398 102269398 JHH4_LIVER 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.R249S 17 7577534 7577534 JHH4_LIVER 37 Missense_Mutation SNP C A rs28934571 uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507484 189507484 JHH4_LIVER 37 Intron SNP T C uc003fry.2 TP63_uc003frx.2... Hybrid_Cap... view
TP63 3 189507518 189507519 JHH4_LIVER 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIB3 p.P142R 20 371983 371983 JHH4_LIVER 37 Missense_Mutation SNP C G rs70961720 uc002wdn.2 TRIB3_uc002wdm.... Hybrid_Cap... view
TRIP13 5 908617 908617 JHH4_LIVER 37 Intron SNP G A uc003jbr.2 TRIP13_uc010ite... Hybrid_Cap... view
TTN 2 179391639 179391640 JHH4_LIVER 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.I26564del 2 179422685 179422687 JHH4_LIVER 37 In_Frame_Del Del AAT - uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.T19556A 2 179446726 179446726 JHH4_LIVER 37 Missense_Mutation SNP T C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.Q3089R 2 179632780 179632780 JHH4_LIVER 37 Missense_Mutation SNP T C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TYRO3 15 41853697 41853697 JHH4_LIVER 37 Intron SNP C T uc001zof.1 TYRO3_uc001zoe.... Hybrid_Cap... view
TYRO3 15 41853990 41853990 JHH4_LIVER 37 Intron SNP G A uc001zof.1 TYRO3_uc001zoe.... Hybrid_Cap... view
UNC13C p.S2205F 15 54919280 54919280 JHH4_LIVER 37 Missense_Mutation SNP C T uc002ack.2 UNC13C_uc002acm... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 JHH4_LIVER 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...