Annotation Summary for Cell Line: JHOS-4  

Cell line primary name: JHOS-4
Cell line aliases:
Gender: F
Site Primary: ovary
Histology: carcinoma
Hist Subtype1: adenocarcinoma
Notes:
Source: RIKEN
Expression arrays: AGENT_p_NCLE_RNA6_HG-U133_Plus_2_B08_436602
SNP arrays: FIEFS_p_NCLE_DNA_Affy5_GenomeWideSNP_6_D10_411016
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in JHOS-4

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABI1 p.G331A 10 27048077 27048077 JHOS4_OVARY 37 Missense_Mutation SNP C G rs2306236 uc001isx.2 ABI1_uc001ite.2... Hybrid_Cap... view
ACACA p.S1523* 17 35548065 35548065 JHOS4_OVARY 37 Nonsense_Mutation SNP G C uc002hno.2 ACACA_uc002hnk.... Hybrid_Cap... view
ADAM12 p.T618I 10 127737895 127737895 JHOS4_OVARY 37 Missense_Mutation SNP G A uc001ljk.2 ADAM12_uc010qul... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 JHOS4_OVARY 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 JHOS4_OVARY 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ARFGEF1 p.E1446_splice 8 68131665 68131665 JHOS4_OVARY 37 Splice_Site_SNP SNP C T uc003xxo.1 ARFGEF1_uc003xx... Hybrid_Cap... view
ATM p.T2674R 11 108205706 108205706 JHOS4_OVARY 37 Missense_Mutation SNP C G uc001pkb.1 ATM_uc009yxr.1_... Hybrid_Cap... view
ATR p.R2109R 3 142188404 142188404 JHOS4_OVARY 37 Silent SNP G A uc003eux.3 ATR_uc003euy.1_... Hybrid_Cap... view
ATRX p.D2216H X 76812975 76812975 JHOS4_OVARY 37 Missense_Mutation SNP C G uc004ecp.3 ATRX_uc004ecq.3... Hybrid_Cap... view
AURKC 19 57742494 57742507 JHOS4_OVARY 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BCL2 18 60985259 60985259 JHOS4_OVARY 37 Intron SNP C A uc002lit.1 BCL2_uc002liu.1... Hybrid_Cap... view
BCR 22 23631813 23631814 JHOS4_OVARY 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BTRC p.L95S 10 103239174 103239174 JHOS4_OVARY 37 Missense_Mutation SNP T C uc001kta.2 BTRC_uc001ksz.1... Hybrid_Cap... view
CABC1 1 227171585 227171585 JHOS4_OVARY 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CACNB2 10 18828721 18828722 JHOS4_OVARY 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CAMKK2 12 121698203 121698203 JHOS4_OVARY 37 Intron SNP A T uc001tzu.2 CAMKK2_uc001tzt... Hybrid_Cap... view
CDKL5 p.Q648* X 18622986 18622986 JHOS4_OVARY 37 Nonsense_Mutation SNP C T uc004cym.2 CDKL5_uc004cyn.... Hybrid_Cap... view
CHD9 p.L1502L 16 53301389 53301389 JHOS4_OVARY 37 Silent SNP C T uc002ehb.2 CHD9_uc002egy.2... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 JHOS4_OVARY 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CSF3R p.R796C 1 36932164 36932164 JHOS4_OVARY 37 Missense_Mutation SNP G A uc001cax.1 MRPS15_uc001cas... Hybrid_Cap... view
CSNK2A2 p.R90S 16 58220709 58220709 JHOS4_OVARY 37 Missense_Mutation SNP G T uc002enc.2 Hybrid_Cap... view
CSPG4 p.F709I 15 75981281 75981281 JHOS4_OVARY 37 Missense_Mutation SNP A T uc002baw.2 Hybrid_Cap... view
DDR2 1 162750211 162750212 JHOS4_OVARY 37 3'UTR Del TT - uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap...
DYRK4 p.K158Q 12 4702176 4702176 JHOS4_OVARY 37 Missense_Mutation SNP A C uc009zeh.1 DYRK4_uc001qmx.... Hybrid_Cap... view
EIF2AK3 p.R698S 2 88874909 88874909 JHOS4_OVARY 37 Missense_Mutation SNP G T uc002stc.3 Hybrid_Cap... view
EIF4G1 p.P571A 3 184040413 184040413 JHOS4_OVARY 37 Missense_Mutation SNP C G uc010hxx.2 EIF4G1_uc003fno... Hybrid_Cap... view
EPHA6 3 97367230 97367231 JHOS4_OVARY 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EXT1 8 118811807 118811807 JHOS4_OVARY 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
FAM132A 1 1177919 1177919 JHOS4_OVARY 37 3'UTR Del T - uc001adl.1 Hybrid_Cap...
FGFR1OP 6 167453519 167453520 JHOS4_OVARY 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 JHOS4_OVARY 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNA X 153577132 153577133 JHOS4_OVARY 37 3'UTR Ins - CA rs10692455;rs71733538 uc004fkk.2 FLNA_uc004fki.2... Hybrid_Cap...
FN1 2 216244182 216244185 JHOS4_OVARY 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FN1 p.T1108M 2 216264005 216264005 JHOS4_OVARY 37 Missense_Mutation SNP G A uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap... view
GLG1 p.W110L 16 74640664 74640664 JHOS4_OVARY 37 Missense_Mutation SNP C A uc002fcx.2 GLG1_uc002fcy.3... Hybrid_Cap... view
GRAMD1B p.G621R 11 123485494 123485494 JHOS4_OVARY 37 Missense_Mutation SNP G C uc001pyw.2 GRAMD1B_uc001py... Hybrid_Cap... view
GRIA3 X 122318386 122318387 JHOS4_OVARY 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIN2B p.D1253Y 12 13716415 13716415 JHOS4_OVARY 37 Missense_Mutation SNP C A uc001rbt.2 Hybrid_Cap... view
GUCY2C 12 14827464 14827466 JHOS4_OVARY 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HNF1A 12 121434630 121434631 JHOS4_OVARY 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSP90AA1 p.E164E 14 102552590 102552590 JHOS4_OVARY 37 Silent SNP C T uc001ykv.3 HSP90AA1_uc001y... Hybrid_Cap... view
HSP90B1 p.E791del 12 104341188 104341190 JHOS4_OVARY 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 JHOS4_OVARY 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 JHOS4_OVARY 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
JUND p.P233L 19 18391597 18391597 JHOS4_OVARY 37 Missense_Mutation SNP G A uc002nip.2 Hybrid_Cap... view
KALRN p.P2255T 3 124390569 124390569 JHOS4_OVARY 37 Missense_Mutation SNP C A uc003ehg.2 KALRN_uc003ehi.... Hybrid_Cap... view
KDM5A 12 498268 498268 JHOS4_OVARY 37 5'UTR Del G - uc001qif.1 KDM5A_uc001qie.... Hybrid_Cap...
LRP2 p.R1742T 2 170088226 170088226 JHOS4_OVARY 37 Missense_Mutation SNP C G uc002ues.2 Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 JHOS4_OVARY 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 JHOS4_OVARY 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPK14 6 36076345 36076354 JHOS4_OVARY 37 3'UTR Del GTGTG... - rs80147786 uc003olp.2 MAPK14_uc003olq... Hybrid_Cap...
MAPKAPK3 3 50685575 50685575 JHOS4_OVARY 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MAST4 p.G1579E 5 66460310 66460310 JHOS4_OVARY 37 Missense_Mutation SNP G A uc003jut.1 MAST4_uc003juw.... Hybrid_Cap... view
MLL3 p.Y816fs 7 151945071 151945072 JHOS4_OVARY 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
MLLT3 9 20346377 20346378 JHOS4_OVARY 37 3'UTR Ins - A rs66943046 uc003zoe.2 MLLT3_uc011lne.... Hybrid_Cap...
MYC p.S235P 8 128751166 128751166 JHOS4_OVARY 37 Missense_Mutation SNP T C uc003ysi.2 Hybrid_Cap... view
MYH1 p.I993V 17 10406189 10406189 JHOS4_OVARY 37 Missense_Mutation SNP T C uc002gmo.2 Hybrid_Cap... view
MYLK 3 123332876 123332876 JHOS4_OVARY 37 3'UTR Del T - rs115544676 uc003ego.2 MYLK_uc003egl.2... Hybrid_Cap...
MYLK3 p.D435H 16 46766279 46766279 JHOS4_OVARY 37 Missense_Mutation SNP C G uc002eei.3 MYLK3_uc010vge.... Hybrid_Cap... view
MYO18B p.R1753Q 22 26304398 26304398 JHOS4_OVARY 37 Missense_Mutation SNP G A uc003abz.1 MYO18B_uc003aca... Hybrid_Cap... view
MYO3B p.H316L 2 171225863 171225863 JHOS4_OVARY 37 Missense_Mutation SNP A T rs55633190 uc002ufy.2 MYO3B_uc002ufv.... Hybrid_Cap... view
MYST4 p.E1104del 10 76781906 76781908 JHOS4_OVARY 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
MYST4 10 76790936 76790936 JHOS4_OVARY 37 3'UTR Del A - uc001jwn.1 MYST4_uc001jwo.... Hybrid_Cap...
NCAM1 11 112832307 112832308 JHOS4_OVARY 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 JHOS4_OVARY 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 JHOS4_OVARY 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 JHOS4_OVARY 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NPM1 5 170837734 170837734 JHOS4_OVARY 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 JHOS4_OVARY 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 JHOS4_OVARY 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
OBSCN 1 228456207 228456207 JHOS4_OVARY 37 Intron SNP G C uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
PAX3 2 223066017 223066018 JHOS4_OVARY 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 JHOS4_OVARY 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDCD11 p.Y1503F 10 105200558 105200558 JHOS4_OVARY 37 Missense_Mutation SNP A T uc001kwy.1 Hybrid_Cap... view
PDE4DIP p.L601fs 1 144915624 144915624 JHOS4_OVARY 37 Frame_Shift_Del Del G - rs1778112 uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.E243fs 1 144923729 144923729 JHOS4_OVARY 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PGR 11 100933598 100933599 JHOS4_OVARY 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PRAME p.V480A 22 22890580 22890580 JHOS4_OVARY 37 Missense_Mutation SNP A G uc002zwf.2 LOC96610_uc011a... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 JHOS4_OVARY 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 JHOS4_OVARY 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROBO2 3 77666937 77666937 JHOS4_OVARY 37 Intron Del A - rs78745603 uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap...
RYK p.R544H 3 133878163 133878163 JHOS4_OVARY 37 Missense_Mutation SNP C T uc003eqc.1 RYK_uc003eqd.1_... Hybrid_Cap... view
SEPT5 22 19709594 19709595 JHOS4_OVARY 37 Intron Ins - C rs71186626 uc002zpv.1 SEPT5_uc002zpw.... Hybrid_Cap...
SMAD2 18 45371467 45371467 JHOS4_OVARY 37 Intron SNP T C uc002lcy.2 SMAD2_uc002lcz.... Hybrid_Cap... view
SSU72 1 1477324 1477325 JHOS4_OVARY 37 3'UTR Del CA - rs72502747 uc001agd.2 C1orf70_uc009vk... Hybrid_Cap...
STK31 7 23872024 23872025 JHOS4_OVARY 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TLR3 p.G12R 4 186997807 186997807 JHOS4_OVARY 37 Missense_Mutation SNP G C uc003iyq.2 Hybrid_Cap... view
TMEM123 11 102269398 102269398 JHOS4_OVARY 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.V147G 17 7578490 7578490 JHOS4_OVARY 37 Missense_Mutation SNP A C uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM33 1 114940211 114940212 JHOS4_OVARY 37 3'UTR Ins - T rs66490349 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TTN 2 179391639 179391640 JHOS4_OVARY 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.H2849Q 2 179634881 179634881 JHOS4_OVARY 37 Missense_Mutation SNP G T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 JHOS4_OVARY 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
VRK3 p.SCSPQKT127del 19 50510972 50510992 JHOS4_OVARY 37 In_Frame_Del Del CTGGT... - rs117711287;rs117077533 uc002prg.2 VRK3_uc002prh.1... Hybrid_Cap...
WNK1 p.E2175Q 12 1009716 1009716 JHOS4_OVARY 37 Missense_Mutation SNP G C uc001qio.3 WNK1_uc001qip.3... Hybrid_Cap... view