Annotation Summary for Cell Line: KE-37  

Cell line primary name: KE-37
Cell line aliases:
Gender: M
Site Primary: haematopoietic_and_lymphoid_tissue
Histology: lymphoid_neoplasm
Hist Subtype1: acute_lymphoblastic_T_cell_leukaemia
Notes:
Source: DSMZ
Expression arrays: SILOS_p_NCLE_RNA9_HG-U133_Plus_2_G11_523586
SNP arrays: MISTS_p_NCLE_DNAAffy11_GenomeWideSNP_6_A07_578392
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in KE-37

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 KE37_HAEMATOPOI... 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACVR1 p.H320Y 2 158622541 158622541 KE37_HAEMATOPOI... 37 Missense_Mutation SNP G A uc002tzm.3 ACVR1_uc002tzn.... Hybrid_Cap... view
ACVR1 p.G111_splice 2 158634856 158634856 KE37_HAEMATOPOI... 37 Splice_Site_SNP SNP T A uc002tzm.3 ACVR1_uc002tzn.... Hybrid_Cap... view
ADAM17 2 9630245 9630245 KE37_HAEMATOPOI... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 KE37_HAEMATOPOI... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS20 p.E1484_splice 12 43792867 43792867 KE37_HAEMATOPOI... 37 Splice_Site_SNP SNP A T uc010skx.1 Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 KE37_HAEMATOPOI... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 KE37_HAEMATOPOI... 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK2 p.I743N 18 56205191 56205191 KE37_HAEMATOPOI... 37 Missense_Mutation SNP A T uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap... view
ALPK2 18 56149003 56149003 KE37_HAEMATOPOI... 37 3'UTR SNP C T uc002lhj.3 Hybrid_Cap... view
ATM p.S1383L 11 108159742 108159742 KE37_HAEMATOPOI... 37 Missense_Mutation SNP C T uc001pkb.1 ATM_uc009yxr.1_... Hybrid_Cap... view
AURKB p.P83P 17 8110646 8110646 KE37_HAEMATOPOI... 37 Silent SNP A G uc002gkn.2 AURKB_uc010cnu.... Hybrid_Cap... view
BRIP1 p.R762P 17 59820468 59820468 KE37_HAEMATOPOI... 37 Missense_Mutation SNP C G uc002izk.1 BRIP1_uc002izl.... Hybrid_Cap... view
CDK11A p.Y579fs 1 1635536 1635537 KE37_HAEMATOPOI... 37 Frame_Shift_Ins Ins - A uc009vks.2 CDK11B_uc001ags... Hybrid_Cap...
CHD1 p.P1684del 5 98192165 98192167 KE37_HAEMATOPOI... 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 KE37_HAEMATOPOI... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 KE37_HAEMATOPOI... 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CXCL12 10 44873992 44873993 KE37_HAEMATOPOI... 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
DDX1 p.I104T 2 15742675 15742675 KE37_HAEMATOPOI... 37 Missense_Mutation SNP T C uc002rce.2 DDX1_uc010yjq.1... Hybrid_Cap... view
DLL1 6 170591831 170591831 KE37_HAEMATOPOI... 37 3'UTR SNP C T uc003qxm.2 Hybrid_Cap... view
DNAH8 p.K3336Q 6 38889277 38889277 KE37_HAEMATOPOI... 37 Missense_Mutation SNP A C uc003ooe.1 Hybrid_Cap... view
DYRK3 p.P520R 1 206822102 206822102 KE37_HAEMATOPOI... 37 Missense_Mutation SNP C G uc001hej.2 DYRK3_uc001hek.... Hybrid_Cap... view
EIF4E 4 99808137 99808141 KE37_HAEMATOPOI... 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
EP300 22 41574970 41574972 KE37_HAEMATOPOI... 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 KE37_HAEMATOPOI... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ERCC3 2 128051385 128051385 KE37_HAEMATOPOI... 37 Intron SNP A T uc002toh.1 ERCC3_uc002toe.... Hybrid_Cap... view
ERCC6 p.R557H 10 50708599 50708599 KE37_HAEMATOPOI... 37 Missense_Mutation SNP C T rs41549213 uc001jhs.3 ERCC6_uc010qgr.... Hybrid_Cap... view
ETV1 7 14028708 14028708 KE37_HAEMATOPOI... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 KE37_HAEMATOPOI... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR2 10 123298088 123298088 KE37_HAEMATOPOI... 37 Intron SNP G A uc010qtj.1 FGFR2_uc010qtg.... Hybrid_Cap... view
FLI1 11 128638217 128638217 KE37_HAEMATOPOI... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 KE37_HAEMATOPOI... 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GAS7 17 9862741 9862741 KE37_HAEMATOPOI... 37 Intron SNP C T uc002gmg.1 GAS7_uc010vvc.1... Hybrid_Cap... view
GRIA3 X 122318386 122318387 KE37_HAEMATOPOI... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIK1 p.I440F 21 30963479 30963479 KE37_HAEMATOPOI... 37 Missense_Mutation SNP T A uc011acs.1 GRIK1_uc002ynn.... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 KE37_HAEMATOPOI... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIPK2 p.R497Q 7 139311476 139311476 KE37_HAEMATOPOI... 37 Missense_Mutation SNP C T uc003vvf.3 HIPK2_uc003vvd.... Hybrid_Cap... view
HNF1A 12 121434630 121434631 KE37_HAEMATOPOI... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSP90B1 p.E791del 12 104341188 104341190 KE37_HAEMATOPOI... 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 KE37_HAEMATOPOI... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 KE37_HAEMATOPOI... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KLK7 19 51480672 51480675 KE37_HAEMATOPOI... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
MAF 16 79628537 79628537 KE37_HAEMATOPOI... 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 KE37_HAEMATOPOI... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 KE37_HAEMATOPOI... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 KE37_HAEMATOPOI... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MLH1 p.P350P 3 37067139 37067139 KE37_HAEMATOPOI... 37 Silent SNP A G uc003cgl.2 MLH1_uc011aye.1... Hybrid_Cap... view
MLLT4 p.Q591P 6 168311786 168311786 KE37_HAEMATOPOI... 37 Missense_Mutation SNP A C uc003qwd.2 MLLT4_uc003qwb.... Hybrid_Cap... view
MLLT6 17 36881873 36881873 KE37_HAEMATOPOI... 37 3'UTR Del C - uc002hqi.3 MLLT6_uc002hqk.... Hybrid_Cap...
MYST4 p.EEE1366del 10 76788660 76788668 KE37_HAEMATOPOI... 37 In_Frame_Del Del GAAGA... - uc001jwn.1 MYST4_uc001jwo.... Hybrid_Cap...
NCAM1 11 112832307 112832308 KE37_HAEMATOPOI... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 KE37_HAEMATOPOI... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 KE37_HAEMATOPOI... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFATC1 18 77287653 77287654 KE37_HAEMATOPOI... 37 3'UTR Del AA - uc010xfg.1 NFATC1_uc002lnd... Hybrid_Cap...
NFIA 1 61921185 61921186 KE37_HAEMATOPOI... 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NPM1 5 170837734 170837734 KE37_HAEMATOPOI... 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 KE37_HAEMATOPOI... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NRAS p.G12D 1 115258747 115258747 KE37_HAEMATOPOI... 37 Missense_Mutation SNP C T uc009wgu.2 Hybrid_Cap... view
PAX3 2 223158653 223158653 KE37_HAEMATOPOI... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAXIP1 p.D774G 7 154752716 154752716 KE37_HAEMATOPOI... 37 Missense_Mutation SNP T C uc003wlp.2 PAXIP1_uc003wlq... Hybrid_Cap... view
PKN2 p.L384del 1 89250482 89250484 KE37_HAEMATOPOI... 37 In_Frame_Del Del TCT - uc001dmn.2 PKN2_uc001dmm.1... Hybrid_Cap...
PLCG1 20 39802181 39802181 KE37_HAEMATOPOI... 37 Intron SNP C T uc002xjo.1 PLCG1_uc002xjp.... Hybrid_Cap... view
PMS1 2 190670539 190670540 KE37_HAEMATOPOI... 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PMS1 p.A755S 2 190728875 190728875 KE37_HAEMATOPOI... 37 Missense_Mutation SNP G T uc002urh.3 PMS1_uc010zgb.1... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 KE37_HAEMATOPOI... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTCH1 p.R571Q 9 98238332 98238332 KE37_HAEMATOPOI... 37 Missense_Mutation SNP C T uc004avk.3 PTCH1_uc010mro.... Hybrid_Cap... view
RANBP17 5 170725871 170725871 KE37_HAEMATOPOI... 37 3'UTR SNP T C uc003mba.2 RANBP17_uc003mb... Hybrid_Cap... view
RCBTB2 p.G176E 13 49086869 49086869 KE37_HAEMATOPOI... 37 Missense_Mutation SNP C T uc010tgg.1 RCBTB2_uc001vch... Hybrid_Cap... view
ROBO2 3 77666937 77666937 KE37_HAEMATOPOI... 37 Intron Del A - rs78745603 uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap...
RPS6KA5 14 91360733 91360734 KE37_HAEMATOPOI... 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
SEPT9 17 75494761 75494761 KE37_HAEMATOPOI... 37 3'UTR SNP G A uc002jts.3 SEPT9_uc010wtk.... Hybrid_Cap... view
STK31 7 23872024 23872025 KE37_HAEMATOPOI... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TCF21 6 134210497 134210498 KE37_HAEMATOPOI... 37 5'UTR Ins - TCTC rs35199378 uc003qei.3 TCF21_uc003qej.... Hybrid_Cap...
TRIM33 1 114940215 114940216 KE37_HAEMATOPOI... 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TTN p.I32793T 2 179395260 179395260 KE37_HAEMATOPOI... 37 Missense_Mutation SNP A G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
UNC13C p.A529E 15 54306686 54306686 KE37_HAEMATOPOI... 37 Missense_Mutation SNP C A uc002ack.2 Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 KE37_HAEMATOPOI... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
ZAK p.I397N 2 174097174 174097174 KE37_HAEMATOPOI... 37 Missense_Mutation SNP T A uc002uhz.2 Hybrid_Cap... view