Annotation Summary for Cell Line: KP-2  

Cell line primary name: KP-2
Cell line aliases:
Gender: F
Site Primary: pancreas
Histology: carcinoma
Hist Subtype1: NS
Notes:
Source: HSRRB
Expression arrays: METIS_p_NCLE_RNA1_Human_U133_Plus_2.0_H07_241030
SNP arrays: ARLES_p_NCLE_DNAAffy2_S_GenomeWideSNP_6_F04_256128
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in KP-2

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 KP2_PANCREAS 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ABL2 1 179086419 179086420 KP2_PANCREAS 37 Intron Ins - A rs72207641 uc001gmj.3 ABL2_uc010pnf.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 KP2_PANCREAS 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADCK1 p.M210V 14 78365488 78365488 KP2_PANCREAS 37 Missense_Mutation SNP A G uc001xui.2 ADCK1_uc010tvo.... Hybrid_Cap... view
AKAP9 p.1335_1336insQ 7 91652178 91652179 KP2_PANCREAS 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
AKT1 p.G478S 14 105236689 105236689 KP2_PANCREAS 37 Missense_Mutation SNP C T uc001ypk.2 INF2_uc010tyi.1... Hybrid_Cap... view
ALK p.M1478T 2 29416520 29416520 KP2_PANCREAS 37 Missense_Mutation SNP A G uc002rmy.2 ALK_uc010ymo.1_... Hybrid_Cap... view
ALPK1 4 113347609 113347610 KP2_PANCREAS 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 KP2_PANCREAS 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ALS2 2 202587706 202587707 KP2_PANCREAS 37 Intron Ins - A rs3219165 uc002uyo.2 ALS2_uc002uyp.3... Hybrid_Cap...
ARHGDIB p.S176F 12 15095535 15095535 KP2_PANCREAS 37 Missense_Mutation SNP G A uc001rcq.1 ARHGDIB_uc001rc... Hybrid_Cap... view
ATR p.K1228E 3 142257367 142257367 KP2_PANCREAS 37 Missense_Mutation SNP T C uc003eux.3 Hybrid_Cap... view
AURKC 19 57742531 57742532 KP2_PANCREAS 37 5'UTR Ins - C uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
CACNB2 10 18828721 18828722 KP2_PANCREAS 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDK11B 1 1654066 1654068 KP2_PANCREAS 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CHRNA5 15 78885615 78885616 KP2_PANCREAS 37 3'UTR Ins - TA rs72534078 uc002bdy.2 CHRNA3_uc002bea... Hybrid_Cap...
CHUK p.K389* 10 101967053 101967053 KP2_PANCREAS 37 Nonsense_Mutation SNP T A uc001kqp.2 Hybrid_Cap... view
CLK4 5 178044217 178044220 KP2_PANCREAS 37 Intron Del AACA - uc003mjf.1 CLK4_uc003mjg.1... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 KP2_PANCREAS 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
DACH1 13 72014625 72014626 KP2_PANCREAS 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DBF4 p.E394D 7 87536635 87536635 KP2_PANCREAS 37 Missense_Mutation SNP G T uc003ujf.1 DBF4_uc003ujh.1... Hybrid_Cap... view
DGKB 7 14216345 14216346 KP2_PANCREAS 37 Intron Ins - AGACT uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap...
DMPK p.G631R 19 46273823 46273823 KP2_PANCREAS 37 Missense_Mutation SNP C G uc002pdi.1 SIX5_uc002pdb.2... Hybrid_Cap... view
DST 6 56323711 56323711 KP2_PANCREAS 37 3'UTR SNP C A uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
DST p.D3677N 6 56394455 56394455 KP2_PANCREAS 37 Missense_Mutation SNP C T uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
DST 6 56507651 56507651 KP2_PANCREAS 37 Intron SNP G A uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
DYRK3 1 206822446 206822446 KP2_PANCREAS 37 3'UTR SNP A G uc001hej.2 DYRK3_uc001hek.... Hybrid_Cap... view
EGF p.E1134fs 4 110932389 110932390 KP2_PANCREAS 37 Frame_Shift_Ins Ins - C rs11569144 uc003hzy.3 EGF_uc011cfu.1_... Hybrid_Cap...
EPHA6 3 97367230 97367231 KP2_PANCREAS 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ETV1 7 14028708 14028708 KP2_PANCREAS 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 KP2_PANCREAS 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 KP2_PANCREAS 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FOXP1 3 71008341 71008342 KP2_PANCREAS 37 3'UTR Ins - T rs11433724;rs114233617 uc003dol.2 FOXP1_uc003dom.... Hybrid_Cap...
FURIN 15 91425133 91425133 KP2_PANCREAS 37 3'UTR SNP G T uc002bpu.1 FES_uc010uqj.1_... Hybrid_Cap... view
GLI3 p.R649Q 7 42012093 42012093 KP2_PANCREAS 37 Missense_Mutation SNP C T uc011kbh.1 GLI3_uc011kbg.1... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 KP2_PANCREAS 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 KP2_PANCREAS 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 KP2_PANCREAS 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HERC2 15 28362342 28362342 KP2_PANCREAS 37 Intron SNP G C uc001zbj.2 HERC2_uc001zbi.... Hybrid_Cap... view
HIF1A 14 62213929 62213930 KP2_PANCREAS 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 KP2_PANCREAS 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 KP2_PANCREAS 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGB1 10 33197131 33197134 KP2_PANCREAS 37 Intron Del CTTT - rs116966876 uc001iwq.3 ITGB1_uc001iwp.... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 KP2_PANCREAS 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KLF6 p.E246K 10 3822362 3822362 KP2_PANCREAS 37 Missense_Mutation SNP C T uc001iha.2 KLF6_uc010qaj.1... Hybrid_Cap... view
KLK7 19 51480672 51480675 KP2_PANCREAS 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KRAS p.G12R 12 25398285 25398285 KP2_PANCREAS 37 Missense_Mutation SNP C G uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
MAMDC4 p.D249D 9 139748739 139748739 KP2_PANCREAS 37 Silent SNP C T uc004cjs.2 MAMDC4_uc011mej... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 KP2_PANCREAS 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K6 17 67516341 67516341 KP2_PANCREAS 37 Intron Del T - uc002jij.2 MAP2K6_uc002jii... Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 KP2_PANCREAS 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K4 p.A1199del 6 161519351 161519353 KP2_PANCREAS 37 In_Frame_Del Del CTG - uc003qtn.2 MAP3K4_uc010kkc... Hybrid_Cap...
MAP4K3 p.G578S 2 39505610 39505610 KP2_PANCREAS 37 Missense_Mutation SNP C T uc002rro.2 MAP4K3_uc002rrp... Hybrid_Cap... view
MYCL1 1 40366352 40366352 KP2_PANCREAS 37 Intron SNP C T uc001cer.1 MYCL1_uc001ces.... Hybrid_Cap... view
NACA p.T1058R 12 57112141 57112141 KP2_PANCREAS 37 Missense_Mutation SNP G C uc009zoy.1 NACA_uc001slz.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 KP2_PANCREAS 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 KP2_PANCREAS 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279864 46279866 KP2_PANCREAS 37 In_Frame_Del Del CAA - rs1132443;rs28529067 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 KP2_PANCREAS 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 KP2_PANCREAS 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NOS3 p.A1132V 7 150710951 150710951 KP2_PANCREAS 37 Missense_Mutation SNP C T uc003wif.2 NOS3_uc011kuy.1... Hybrid_Cap... view
NPR1 1 153665919 153665920 KP2_PANCREAS 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 KP2_PANCREAS 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NSD1 p.Q2579E 5 176722104 176722104 KP2_PANCREAS 37 Missense_Mutation SNP C G uc003mfr.3 NSD1_uc003mft.3... Hybrid_Cap... view
PAPPA p.D912A 9 119028138 119028138 KP2_PANCREAS 37 Missense_Mutation SNP A C uc004bjn.2 PAPPA_uc011lxp.... Hybrid_Cap... view
PAX3 2 223066017 223066018 KP2_PANCREAS 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 KP2_PANCREAS 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PGR 11 100933598 100933599 KP2_PANCREAS 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2A 11 17111198 17111199 KP2_PANCREAS 37 3'UTR Del GT - uc001mmq.3 PIK3C2A_uc009yg... Hybrid_Cap...
PIK3CD p.E790G 1 9782364 9782364 KP2_PANCREAS 37 Missense_Mutation SNP A G uc001aqe.3 PIK3CD_uc001aqb... Hybrid_Cap... view
PLCG1 p.T61M 20 39766463 39766463 KP2_PANCREAS 37 Missense_Mutation SNP C T uc002xjo.1 PLCG1_uc002xjp.... Hybrid_Cap... view
PLD1 p.G232E 3 171442549 171442549 KP2_PANCREAS 37 Missense_Mutation SNP C T uc003fhs.2 PLD1_uc003fht.2... Hybrid_Cap... view
PMS1 2 190670539 190670540 KP2_PANCREAS 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PPP3R2 9 104356523 104356523 KP2_PANCREAS 37 3'UTR SNP G C rs3739725 uc004bbr.2 GRIN3A_uc004bbp... Hybrid_Cap... view
PREX2 8 69143713 69143714 KP2_PANCREAS 37 3'UTR Del TT - uc003xxv.1 Hybrid_Cap...
PRKACA 19 14203876 14203882 KP2_PANCREAS 37 3'UTR Del AAAAA... - uc002myc.2 SAMD1_uc010xnl.... Hybrid_Cap...
PRKCB 16 24231324 24231324 KP2_PANCREAS 37 3'UTR SNP A G uc002dme.2 PRKCB_uc002dmd.... Hybrid_Cap... view
PRKD3 p.R113H 2 37520365 37520365 KP2_PANCREAS 37 Missense_Mutation SNP C T uc002rqd.2 PRKD3_uc002rqf.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 KP2_PANCREAS 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RAGE p.E132K 14 102718110 102718110 KP2_PANCREAS 37 Missense_Mutation SNP C T uc001ylm.2 RAGE_uc010txv.1... Hybrid_Cap... view
RBBP8 p.M715_splice 18 20581532 20581532 KP2_PANCREAS 37 Splice_Site_SNP SNP A G uc002kua.2 RBBP8_uc002ktw.... Hybrid_Cap... view
RIOK3 18 21061418 21061418 KP2_PANCREAS 37 3'UTR SNP G C uc002kui.3 RIOK3_uc010dls.... Hybrid_Cap... view
ROBO2 3 77666937 77666937 KP2_PANCREAS 37 Intron Del A - rs78745603 uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap...
RPN1 p.W239L 3 128350918 128350918 KP2_PANCREAS 37 Missense_Mutation SNP C A uc003ekr.1 RPN1_uc011bkq.1... Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 KP2_PANCREAS 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SGK223 p.R623W 8 8234052 8234052 KP2_PANCREAS 37 Missense_Mutation SNP G A uc003wsh.3 Hybrid_Cap... view
SMAD4 p.L414fs 18 48593491 48593494 KP2_PANCREAS 37 Frame_Shift_Del Del AGAC - uc010xdp.1 SMAD4_uc002lfb.... Hybrid_Cap...
SRC p.R163W 20 36022614 36022614 KP2_PANCREAS 37 Missense_Mutation SNP C T uc002xgx.2 SRC_uc002xgy.2_... Hybrid_Cap... view
STK31 7 23872024 23872025 KP2_PANCREAS 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
STK4 p.R117Q 20 43610574 43610574 KP2_PANCREAS 37 Missense_Mutation SNP G A uc002xnb.2 STK4_uc010ggx.2... Hybrid_Cap... view
TAF1L 9 32630062 32630062 KP2_PANCREAS 37 3'UTR Del C - uc003zrg.1 Hybrid_Cap...
TCERG1L p.D548Y 10 132891544 132891544 KP2_PANCREAS 37 Missense_Mutation SNP C A uc001lkp.2 Hybrid_Cap... view
TLE1 p.R126C 9 84267125 84267125 KP2_PANCREAS 37 Missense_Mutation SNP G A uc004alz.2 TLE1_uc004aly.2... Hybrid_Cap... view
TP53 p.A161D 17 7578448 7578448 KP2_PANCREAS 37 Missense_Mutation SNP G T uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TSC2 p.C1755W 16 2138452 2138452 KP2_PANCREAS 37 Missense_Mutation SNP C G uc002con.2 TSC2_uc010bsd.2... Hybrid_Cap... view
TTN p.K24758N 2 179428881 179428881 KP2_PANCREAS 37 Missense_Mutation SNP T A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.R11511Q 2 179499272 179499272 KP2_PANCREAS 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.P6579T 2 179584902 179584902 KP2_PANCREAS 37 Missense_Mutation SNP G T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN 2 179611247 179611247 KP2_PANCREAS 37 Intron SNP A T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.S3357T 2 179628949 179628949 KP2_PANCREAS 37 Missense_Mutation SNP A T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
UBR5 p.R1907H 8 103293724 103293724 KP2_PANCREAS 37 Missense_Mutation SNP C T uc003ykr.1 UBR5_uc003yks.1... Hybrid_Cap... view
UBR5 p.A1738fs 8 103298589 103298589 KP2_PANCREAS 37 Frame_Shift_Del Del T - uc003ykr.1 UBR5_uc003yks.1... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 KP2_PANCREAS 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WHSC1 p.G945fs 4 1957868 1957869 KP2_PANCREAS 37 Frame_Shift_Ins Ins - C uc003gdz.3 WHSC1_uc003geb.... Hybrid_Cap...
XIAP p.E350del X 123025155 123025157 KP2_PANCREAS 37 In_Frame_Del Del GAG - uc010nqu.2 XIAP_uc004etx.2... Hybrid_Cap...