Annotation Summary for Cell Line: KP-3  

Cell line primary name: KP-3
Cell line aliases:
Gender:
Site Primary: pancreas
Histology: carcinoma
Hist Subtype1: ductal_carcinoma
Notes:
Source: HSRRB
Expression arrays: BUNDS_p_NCLE_RNA5_HG-U133_Plus_2_C04_419704
SNP arrays: FIEFS_p_NCLE_DNA_Affy5_GenomeWideSNP_6_F12_410960
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in KP-3

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABL2 p.P109L 1 179100511 179100511 KP3_PANCREAS 37 Missense_Mutation SNP G A uc001gmj.3 ABL2_uc010pnf.1... Hybrid_Cap... view
ADAM28 8 24211994 24211997 KP3_PANCREAS 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 KP3_PANCREAS 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALK p.M1478T 2 29416520 29416520 KP3_PANCREAS 37 Missense_Mutation SNP A G uc002rmy.2 ALK_uc010ymo.1_... Hybrid_Cap... view
ALPK2 p.EDTST1006del 18 56204388 56204402 KP3_PANCREAS 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ARID1A p.T2138fs 1 27106803 27106804 KP3_PANCREAS 37 Frame_Shift_Ins Ins - C uc001bmv.1 ARID1A_uc001bmu... Hybrid_Cap...
ASH2L p.H538R 8 37991057 37991057 KP3_PANCREAS 37 Missense_Mutation SNP A G uc003xkt.3 ASH2L_uc011lbk.... Hybrid_Cap... view
ASPH p.A264_splice 8 62550924 62550925 KP3_PANCREAS 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
AURKC 19 57742494 57742507 KP3_PANCREAS 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BCL2A1 15 80253390 80253390 KP3_PANCREAS 37 3'UTR SNP T C uc002bfc.3 BCL2A1_uc002bfd... Hybrid_Cap... view
CACNB2 10 18828721 18828722 KP3_PANCREAS 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDK11B 1 1654066 1654068 KP3_PANCREAS 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CHRNA5 15 78885615 78885616 KP3_PANCREAS 37 3'UTR Ins - TA rs72534078 uc002bdy.2 CHRNA3_uc002bea... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 KP3_PANCREAS 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 KP3_PANCREAS 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
DTX1 p.R440C 12 113532684 113532684 KP3_PANCREAS 37 Missense_Mutation SNP C T uc001tuk.1 Hybrid_Cap... view
ERCC6 p.R735L 10 50686482 50686482 KP3_PANCREAS 37 Missense_Mutation SNP C A uc001jhs.3 ERCC6_uc009xod.... Hybrid_Cap... view
EXT1 8 118811807 118811807 KP3_PANCREAS 37 3'UTR Del T - uc003yok.1 Hybrid_Cap...
FGFR1OP 6 167453519 167453520 KP3_PANCREAS 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLNA p.N931D X 153590382 153590382 KP3_PANCREAS 37 Missense_Mutation SNP T C uc004fkk.2 FLNA_uc010nuu.1... Hybrid_Cap... view
FLT3 p.P336L 13 28623550 28623550 KP3_PANCREAS 37 Missense_Mutation SNP G A uc001urw.2 FLT3_uc010aao.2... Hybrid_Cap... view
FN1 2 216244182 216244185 KP3_PANCREAS 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GNAS p.L20M 20 57415219 57415219 KP3_PANCREAS 37 Missense_Mutation SNP C A uc002xzt.2 GNASAS_uc002xzs... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 KP3_PANCREAS 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 KP3_PANCREAS 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 KP3_PANCREAS 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HNF1A 12 121434630 121434631 KP3_PANCREAS 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
IL1R2 2 102624981 102624981 KP3_PANCREAS 37 De_novo_Start_OutOfFrame SNP C T uc002tbm.2 IL1R2_uc002tbn.... Hybrid_Cap... view
ILK 11 6630029 6630029 KP3_PANCREAS 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 KP3_PANCREAS 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KRAS p.G12V 12 25398284 25398284 KP3_PANCREAS 37 Missense_Mutation SNP C A uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap... view
LASP1 17 37026319 37026319 KP3_PANCREAS 37 5'UTR SNP C T uc002hra.2 LASP1_uc010wdy.... Hybrid_Cap... view
LEMD1 1 205350721 205350721 KP3_PANCREAS 37 3'UTR SNP T G uc001hci.1 LEMD1_uc001hcj.... Hybrid_Cap... view
LRRC7 p.A716T 1 70502279 70502279 KP3_PANCREAS 37 Missense_Mutation SNP G A uc001dep.2 LRRC7_uc009wbg.... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 KP3_PANCREAS 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K1 15 66679649 66679650 KP3_PANCREAS 37 5'UTR Ins - C rs67229745 uc010bhq.2 Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 KP3_PANCREAS 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 KP3_PANCREAS 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K4 p.A1199del 6 161519351 161519353 KP3_PANCREAS 37 In_Frame_Del Del CTG - uc003qtn.2 MAP3K4_uc010kkc... Hybrid_Cap...
MAPK10 p.L14L 4 87115515 87115515 KP3_PANCREAS 37 Silent SNP A G uc003hpq.2 MAPK10_uc010ikg... Hybrid_Cap... view
MAPKAPK3 3 50685575 50685575 KP3_PANCREAS 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MYLK p.E1066del 3 123419117 123419119 KP3_PANCREAS 37 In_Frame_Del Del TTC - rs72491150 uc003ego.2 MYLK_uc011bjw.1... Hybrid_Cap...
MYST4 p.K1243R 10 76788310 76788310 KP3_PANCREAS 37 Missense_Mutation SNP A G uc001jwn.1 MYST4_uc001jwo.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 KP3_PANCREAS 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 KP3_PANCREAS 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279864 46279866 KP3_PANCREAS 37 In_Frame_Del Del CAA - rs1132443;rs28529067 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK10 p.T712T 3 27257326 27257326 KP3_PANCREAS 37 Silent SNP T C uc003cdt.1 NEK10_uc003cds.... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 KP3_PANCREAS 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 KP3_PANCREAS 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NOTCH4 p.15_16LL>L 6 32191659 32191661 KP3_PANCREAS 37 In_Frame_Del Del AGC - uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap...
NPM1 5 170837734 170837734 KP3_PANCREAS 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 KP3_PANCREAS 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NSD1 p.V2618I 5 176722221 176722221 KP3_PANCREAS 37 Missense_Mutation SNP G A uc003mfr.3 NSD1_uc003mft.3... Hybrid_Cap... view
PAX3 2 223066017 223066018 KP3_PANCREAS 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 KP3_PANCREAS 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP p.L601fs 1 144915624 144915624 KP3_PANCREAS 37 Frame_Shift_Del Del G - rs1778112 uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.E243fs 1 144923729 144923729 KP3_PANCREAS 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDGFRB p.R685C 5 149502735 149502735 KP3_PANCREAS 37 Missense_Mutation SNP G A uc003lro.2 PDGFRB_uc010jhd... Hybrid_Cap... view
PGGT1B 5 114548071 114548072 KP3_PANCREAS 37 3'UTR Ins - C uc003kqw.3 PGGT1B_uc003kqx... Hybrid_Cap...
PGR 11 100933598 100933599 KP3_PANCREAS 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2A 11 17111198 17111199 KP3_PANCREAS 37 3'UTR Del GT - uc001mmq.3 PIK3C2A_uc009yg... Hybrid_Cap...
PMS1 2 190670539 190670540 KP3_PANCREAS 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PRKD1 p.Q876* 14 30046557 30046557 KP3_PANCREAS 37 Nonsense_Mutation SNP G A uc001wqh.2 Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 KP3_PANCREAS 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 KP3_PANCREAS 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
SEPT9 17 75494787 75494788 KP3_PANCREAS 37 3'UTR Ins - C rs5822173 uc002jts.3 SEPT9_uc010wtk.... Hybrid_Cap...
SMAD4 p.E538* 18 48604790 48604790 KP3_PANCREAS 37 Nonsense_Mutation SNP G T uc010xdp.1 SMAD4_uc002lfb.... Hybrid_Cap... view
SPEN p.R1859W 1 16258310 16258310 KP3_PANCREAS 37 Missense_Mutation SNP C T uc001axk.1 SPEN_uc010obp.1... Hybrid_Cap... view
STK31 7 23872024 23872025 KP3_PANCREAS 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
SULF2 p.R39H 20 46385992 46385992 KP3_PANCREAS 37 Missense_Mutation SNP C T uc002xto.2 SULF2_uc002xtr.... Hybrid_Cap... view
TAF1 p.R1029H X 70612819 70612819 KP3_PANCREAS 37 Missense_Mutation SNP G A uc004dzt.3 BCYRN1_uc011mpt... Hybrid_Cap... view
TEC 4 48139307 48139310 KP3_PANCREAS 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TGS1 p.S96G 8 56698397 56698397 KP3_PANCREAS 37 Missense_Mutation SNP A G uc003xsj.3 TGS1_uc010lyh.2... Hybrid_Cap... view
TLK1 2 171850178 171850179 KP3_PANCREAS 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TLK1 2 172017040 172017040 KP3_PANCREAS 37 5'UTR SNP C G uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap... view
TMEM123 11 102269398 102269398 KP3_PANCREAS 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.P152fs 17 7578474 7578475 KP3_PANCREAS 37 Frame_Shift_Ins Ins - G uc002gim.2 TP53_uc002gig.1... Hybrid_Cap...
TTBK2 p.P487A 15 43067872 43067873 KP3_PANCREAS 37 Missense_Mutation DNP GG CT uc001zqo.2 TTBK2_uc010bcy.... Hybrid_Cap...
TTN 2 179391639 179391640 KP3_PANCREAS 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
UBR5 p.V848A 8 103323600 103323600 KP3_PANCREAS 37 Missense_Mutation SNP A G uc003ykr.1 UBR5_uc003yks.1... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 KP3_PANCREAS 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
VRK1 14 97347652 97347652 KP3_PANCREAS 37 3'UTR SNP A G uc001yft.2 Hybrid_Cap... view
ZAK p.S599P 2 174130870 174130870 KP3_PANCREAS 37 Missense_Mutation SNP T C uc002uhz.2 Hybrid_Cap... view