Annotation Summary for Cell Line: KYSE-70  

Cell line primary name: KYSE-70
Cell line aliases:
Gender: M
Site Primary: oesophagus
Histology: carcinoma
Hist Subtype1: squamous_cell_carcinoma
Notes:
Source: DSMZ
Expression arrays: NIECE_p_NCLE_RNA3_HG-U133_Plus_2_B05_296022
SNP arrays: HONEY_p_NCLE_DNAAffy3_S_GenomeWideSNP_6_C11_293348
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in KYSE-70

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 KYSE70_OESOPHAG... 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACOXL p.V446M 2 111789258 111789258 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G A uc010yxk.1 ACOXL_uc010fkc.... Hybrid_Cap... view
ACVR2A p.Y137fs 2 148657349 148657349 KYSE70_OESOPHAG... 37 Frame_Shift_Del Del A - uc002twg.2 ACVR2A_uc010zbn... Hybrid_Cap...
ADAM28 8 24211994 24211997 KYSE70_OESOPHAG... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 KYSE70_OESOPHAG... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK1 4 113347609 113347610 KYSE70_OESOPHAG... 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 KYSE70_OESOPHAG... 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ARAF p.D146E X 47424518 47424518 KYSE70_OESOPHAG... 37 Missense_Mutation SNP C G uc011mlq.1 ARAF_uc011mln.1... Hybrid_Cap... view
ARHGEF12 p.T1324S 11 120350873 120350873 KYSE70_OESOPHAG... 37 Missense_Mutation SNP C G uc001pxl.1 ARHGEF12_uc009z... Hybrid_Cap... view
ARID1A p.R1989* 1 27106354 27106354 KYSE70_OESOPHAG... 37 Nonsense_Mutation SNP C T uc001bmv.1 ARID1A_uc001bmu... Hybrid_Cap... view
ATP10A p.Q920_splice 15 25947062 25947062 KYSE70_OESOPHAG... 37 Splice_Site_SNP SNP C T uc010ayu.2 Hybrid_Cap... view
ATP13A5 p.C634fs 3 193039485 193039485 KYSE70_OESOPHAG... 37 Frame_Shift_Del Del A - uc011bsq.1 Hybrid_Cap...
AURKC p.E240Q 19 57746385 57746385 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G C uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap... view
BCL2L1 p.S43L 20 30309894 30309894 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G A uc002wwl.2 BCL2L1_uc002wwk... Hybrid_Cap... view
CABC1 p.R182Q 1 227153068 227153068 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G A uc001hqm.1 CABC1_uc010pvp.... Hybrid_Cap... view
CACNB2 10 18828721 18828722 KYSE70_OESOPHAG... 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDKN1B p.E86K 12 12871029 12871029 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G A uc001rat.2 Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 KYSE70_OESOPHAG... 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CIT p.L1435F 12 120152005 120152005 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G A uc001txj.1 CIT_uc001txh.1_... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 KYSE70_OESOPHAG... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN5 p.E554E 11 100061939 100061939 KYSE70_OESOPHAG... 37 Silent SNP A G uc001pga.2 CNTN5_uc009ywv.... Hybrid_Cap... view
CNTN6 3 1339681 1339686 KYSE70_OESOPHAG... 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
COL1A1 p.G1423S 17 48262991 48262991 KYSE70_OESOPHAG... 37 Missense_Mutation SNP C T uc002iqm.2 Hybrid_Cap... view
CREB3L2 p.T100del 7 137612914 137612916 KYSE70_OESOPHAG... 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CTBP2 p.R102C 10 126716025 126716025 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G A uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap... view
CTNNA2 p.E76K 2 79971636 79971636 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G A uc010ysh.1 CTNNA2_uc010yse... Hybrid_Cap... view
CXCL12 10 44873992 44873993 KYSE70_OESOPHAG... 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
DGKB 7 14216330 14216332 KYSE70_OESOPHAG... 37 Intron Del AAC - uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap...
DST p.A1381P 6 56495084 56495084 KYSE70_OESOPHAG... 37 Missense_Mutation SNP C G uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
EGFR p.T68fs 7 55210093 55210093 KYSE70_OESOPHAG... 37 Frame_Shift_Del Del C - uc003tqk.2 EGFR_uc003tqh.2... Hybrid_Cap...
EGFR 7 55238134 55238134 KYSE70_OESOPHAG... 37 Intron SNP C G uc003tqk.2 EGFR_uc003tqj.2... Hybrid_Cap... view
EPHA4 p.A291D 2 222365844 222365844 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G T uc002vmq.2 EPHA4_uc002vmr.... Hybrid_Cap... view
EPHA7 p.G117E 6 94120701 94120701 KYSE70_OESOPHAG... 37 Missense_Mutation SNP C T uc003poe.2 EPHA7_uc003pof.... Hybrid_Cap... view
ERCC6 p.P740S 10 50686468 50686468 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G A uc001jhs.3 ERCC6_uc009xod.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 KYSE70_OESOPHAG... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 p.N720S 4 1808395 1808395 KYSE70_OESOPHAG... 37 Missense_Mutation SNP A G uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap... view
FH p.P192S 1 241672067 241672067 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G A uc001hyx.2 Hybrid_Cap... view
FLI1 11 128638217 128638217 KYSE70_OESOPHAG... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 KYSE70_OESOPHAG... 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 KYSE70_OESOPHAG... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
HDAC3 p.V280I 5 141005843 141005843 KYSE70_OESOPHAG... 37 Missense_Mutation SNP C T uc003llf.2 HDAC3_uc003lle.... Hybrid_Cap... view
HIF1A 14 62213929 62213930 KYSE70_OESOPHAG... 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 KYSE70_OESOPHAG... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSPA1A 6 31785532 31785532 KYSE70_OESOPHAG... 37 3'UTR SNP G T uc003nxj.2 HSPA1L_uc003nxh... Hybrid_Cap... view
ILK 11 6630029 6630029 KYSE70_OESOPHAG... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 KYSE70_OESOPHAG... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KALRN p.E585D 3 124066103 124066103 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G T uc003ehg.2 KALRN_uc010hrv.... Hybrid_Cap... view
KIAA1409 p.E1059K 14 94069716 94069716 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G A uc001ybv.1 KIAA1409_uc001y... Hybrid_Cap... view
KIAA1409 p.R1257Q 14 94084548 94084548 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G A uc001ybv.1 KIAA1409_uc001y... Hybrid_Cap... view
KIT p.G779C 4 55598138 55598138 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G T uc010igr.2 KIT_uc010igs.2_... Hybrid_Cap... view
KSR2 p.R439M 12 117993089 117993089 KYSE70_OESOPHAG... 37 Missense_Mutation SNP C A uc001two.2 Hybrid_Cap... view
LAMA1 p.K1599T 18 6997751 6997751 KYSE70_OESOPHAG... 37 Missense_Mutation SNP T G uc002knm.2 LAMA1_uc010wzj.... Hybrid_Cap... view
LRP1 p.R3901C 12 57600366 57600366 KYSE70_OESOPHAG... 37 Missense_Mutation SNP C T uc001snd.2 Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 KYSE70_OESOPHAG... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAML3 p.I740T 4 140651670 140651670 KYSE70_OESOPHAG... 37 Missense_Mutation SNP A G uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap... view
MAP2K1 15 66679649 66679650 KYSE70_OESOPHAG... 37 5'UTR Ins - C rs67229745 uc010bhq.2 Hybrid_Cap...
MAP2K6 p.I158T 17 67516517 67516517 KYSE70_OESOPHAG... 37 Missense_Mutation SNP T C uc002jij.2 MAP2K6_uc002jii... Hybrid_Cap... view
MAP3K1 p.T949del 5 56177849 56177851 KYSE70_OESOPHAG... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 KYSE70_OESOPHAG... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MCM4 p.D757N 8 48887426 48887426 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G A uc003xqk.1 MCM4_uc003xql.1... Hybrid_Cap... view
MYO3A p.R181S 10 26305781 26305781 KYSE70_OESOPHAG... 37 Missense_Mutation SNP C A uc001isn.2 MYO3A_uc009xko.... Hybrid_Cap... view
MYO3B p.N388S 2 171239677 171239677 KYSE70_OESOPHAG... 37 Missense_Mutation SNP A G rs34273653 uc002ufy.2 MYO3B_uc002ufv.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 KYSE70_OESOPHAG... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 KYSE70_OESOPHAG... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279864 46279866 KYSE70_OESOPHAG... 37 In_Frame_Del Del CAA - rs1132443;rs28529067 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NFIA 1 61921185 61921186 KYSE70_OESOPHAG... 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NOTCH4 p.12_16LLLLL>L 6 32191659 32191670 KYSE70_OESOPHAG... 37 In_Frame_Del Del AGCAG... - uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap...
NPM1 5 170837734 170837734 KYSE70_OESOPHAG... 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 KYSE70_OESOPHAG... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NPRL2 3 50384978 50384978 KYSE70_OESOPHAG... 37 3'UTR Del C - rs75013672 uc003daj.1 ZMYND10_uc003da... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 KYSE70_OESOPHAG... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
OBSCN p.Q5973* 1 228529198 228529198 KYSE70_OESOPHAG... 37 Nonsense_Mutation SNP C T uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
PAX3 2 223158653 223158653 KYSE70_OESOPHAG... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PCM1 8 17813217 17813218 KYSE70_OESOPHAG... 37 Intron Ins - T rs75667844 uc003wyi.3 PCM1_uc011kyh.1... Hybrid_Cap...
PHKG2 16 30762837 30762840 KYSE70_OESOPHAG... 37 Intron Del TCTG - uc002dzi.1 PHKG2_uc002dzj.... Hybrid_Cap...
PIK3C3 p.Q326* 18 39576686 39576686 KYSE70_OESOPHAG... 37 Nonsense_Mutation SNP C T uc002lap.2 PIK3C3_uc010xcl... Hybrid_Cap... view
PIK3R2 p.W330R 19 18273098 18273098 KYSE70_OESOPHAG... 37 Missense_Mutation SNP T C uc002nia.1 PIK3R2_uc002nib... Hybrid_Cap... view
PIP4K2A p.I49_splice 10 22898648 22898648 KYSE70_OESOPHAG... 37 Splice_Site_SNP SNP T A rs113626982 uc001irl.3 Hybrid_Cap... view
PRKD3 p.S735T 2 37484015 37484015 KYSE70_OESOPHAG... 37 Missense_Mutation SNP A T uc002rqd.2 PRKD3_uc002rqe.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 KYSE70_OESOPHAG... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RBL1 p.Q348E 20 35690528 35690528 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G C uc002xgi.2 RBL1_uc010zvt.1... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 KYSE70_OESOPHAG... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RELA 11 65423109 65423109 KYSE70_OESOPHAG... 37 Intron SNP C A uc010ron.1 RELA_uc001ofg.2... Hybrid_Cap... view
RELA 11 65423116 65423116 KYSE70_OESOPHAG... 37 Intron SNP G A uc010ron.1 RELA_uc001ofg.2... Hybrid_Cap... view
RGL3 p.W362* 19 11516014 11516014 KYSE70_OESOPHAG... 37 Nonsense_Mutation SNP C T uc002mro.2 RGL3_uc002mrn.2... Hybrid_Cap... view
RHEB p.S68P 7 151174492 151174492 KYSE70_OESOPHAG... 37 Missense_Mutation SNP A G uc003wkh.1 Hybrid_Cap... view
RICTOR p.L1545P 5 38945664 38945664 KYSE70_OESOPHAG... 37 Missense_Mutation SNP A G uc003jlo.2 RICTOR_uc003jlp... Hybrid_Cap... view
RICTOR p.E251_splice 5 38981968 38981968 KYSE70_OESOPHAG... 37 Splice_Site_SNP SNP C T uc003jlo.2 RICTOR_uc003jlp... Hybrid_Cap... view
RPGRIP1 p.S601W 14 21792816 21792816 KYSE70_OESOPHAG... 37 Missense_Mutation SNP C G rs3748360 uc001wag.2 RPGRIP1_uc001wa... Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 KYSE70_OESOPHAG... 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
RXRA p.V79V 9 137293686 137293686 KYSE70_OESOPHAG... 37 Silent SNP G A uc004cfb.2 RXRA_uc004cfa.1... Hybrid_Cap... view
SGK494 p.I109L 17 26940363 26940363 KYSE70_OESOPHAG... 37 Missense_Mutation SNP T G uc002hbr.1 SGK494_uc010waq... Hybrid_Cap... view
SORL1 p.T1483A 11 121466409 121466409 KYSE70_OESOPHAG... 37 Missense_Mutation SNP A G uc001pxx.2 SORL1_uc010rzp.... Hybrid_Cap... view
SPEG p.A2652T 2 220353315 220353315 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G A uc010fwg.2 Hybrid_Cap... view
STK31 7 23872024 23872025 KYSE70_OESOPHAG... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
STYK1 p.R379C 12 10772877 10772877 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G A uc001qys.2 Hybrid_Cap... view
TEC 4 48139307 48139310 KYSE70_OESOPHAG... 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TFDP1 13 114291977 114291977 KYSE70_OESOPHAG... 37 Intron SNP C T uc001vtw.2 TFDP1_uc010tkd.... Hybrid_Cap... view
TGFB2 1 218519928 218519929 KYSE70_OESOPHAG... 37 5'UTR Ins - AAAC uc001hln.2 TGFB2_uc001hll.... Hybrid_Cap...
TLK1 2 171850178 171850179 KYSE70_OESOPHAG... 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TNK2 p.S666S 3 195595360 195595360 KYSE70_OESOPHAG... 37 Silent SNP G C uc003fvt.1 TNK2_uc003fvq.1... Hybrid_Cap... view
TP53 p.I251fs 17 7577529 7577530 KYSE70_OESOPHAG... 37 Frame_Shift_Ins Ins - T rs67026029 uc002gim.2 TP53_uc002gig.1... Hybrid_Cap...
TP63 3 189507518 189507519 KYSE70_OESOPHAG... 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIM33 1 114940212 114940212 KYSE70_OESOPHAG... 37 3'UTR Del T - uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TTN p.T28771I 2 179412337 179412337 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.P19213R 2 179448567 179448567 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.T5244S 2 179593088 179593088 KYSE70_OESOPHAG... 37 Missense_Mutation SNP G C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.G1955E 2 179640727 179640727 KYSE70_OESOPHAG... 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 KYSE70_OESOPHAG... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
VPS13B p.T779N 8 100205106 100205106 KYSE70_OESOPHAG... 37 Missense_Mutation SNP C A uc003yiv.2 VPS13B_uc003yiw... Hybrid_Cap... view
WNK2 p.A243V 9 95992024 95992024 KYSE70_OESOPHAG... 37 Missense_Mutation SNP C T uc004ati.1 WNK2_uc011lud.1... Hybrid_Cap... view