Annotation Summary for Cell Line: LN-229  

Cell line primary name: LN-229
Cell line aliases:
Gender: F
Site Primary: central_nervous_system
Histology: glioma
Hist Subtype1: astrocytoma_Grade_IV
Notes:
Source: ATCC
Expression arrays: AGENT_p_NCLE_RNA6_HG-U133_Plus_2_C01_436536
SNP arrays: PODIA_p_NCLE_DNAAffy7_GenomeWideSNP_6_B03_437536
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in LN-229

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM17 2 9630245 9630245 LN229_CENTRAL_N... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 LN229_CENTRAL_N... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 LN229_CENTRAL_N... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP4 p.D478N X 49957932 49957932 LN229_CENTRAL_N... 37 Missense_Mutation SNP C T uc004dow.1 AKAP4_uc004dov.... Hybrid_Cap... view
BAI3 p.L220F 6 69349227 69349227 LN229_CENTRAL_N... 37 Missense_Mutation SNP A T uc003pev.3 BAI3_uc010kak.2... Hybrid_Cap... view
BAT3 p.E724D 6 31609962 31609962 LN229_CENTRAL_N... 37 Missense_Mutation SNP T A uc003nvg.3 BAT3_uc003nvf.3... Hybrid_Cap... view
BCL3 19 45262965 45262965 LN229_CENTRAL_N... 37 3'UTR Del C - uc010xxe.1 Hybrid_Cap...
BUB1 p.H1033N 2 111395702 111395702 LN229_CENTRAL_N... 37 Missense_Mutation SNP G T uc002tgc.2 BUB1_uc010yxh.1... Hybrid_Cap... view
CAMKV p.P436S 3 49896951 49896951 LN229_CENTRAL_N... 37 Missense_Mutation SNP G A uc003cxt.1 TRAIP_uc003cxs.... Hybrid_Cap... view
CDC25C p.E112Q 5 137666770 137666770 LN229_CENTRAL_N... 37 Missense_Mutation SNP C G uc003lcs.1 CDC25C_uc003lcp... Hybrid_Cap... view
CDKL2 p.S119T 4 76539446 76539446 LN229_CENTRAL_N... 37 Missense_Mutation SNP C G uc011cbp.1 CDKL2_uc003hiq.... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 LN229_CENTRAL_N... 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CIC p.S694C 19 42795001 42795001 LN229_CENTRAL_N... 37 Missense_Mutation SNP C G uc002otf.1 Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 LN229_CENTRAL_N... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 LN229_CENTRAL_N... 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
COL14A1 p.S1509I 8 121326241 121326241 LN229_CENTRAL_N... 37 Missense_Mutation SNP G T uc003yox.2 COL14A1_uc003yo... Hybrid_Cap... view
EIF4E 4 99808137 99808141 LN229_CENTRAL_N... 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
ELK1 p.N51H X 47500690 47500690 LN229_CENTRAL_N... 37 Missense_Mutation SNP T G uc004dik.3 ELK1_uc010nhv.2... Hybrid_Cap... view
EPHA6 3 97367230 97367231 LN229_CENTRAL_N... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHB6 p.H339P 7 142563299 142563299 LN229_CENTRAL_N... 37 Missense_Mutation SNP A C uc011kst.1 EPHB6_uc011ksu.... Hybrid_Cap... view
ERBB2 p.L755S 17 37880220 37880220 LN229_CENTRAL_N... 37 Missense_Mutation SNP T C uc002hso.2 ERBB2_uc002hsm.... Hybrid_Cap... view
ETV1 7 14028708 14028708 LN229_CENTRAL_N... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FANCC p.Q3H 9 98011565 98011565 LN229_CENTRAL_N... 37 Missense_Mutation SNP T A uc004avh.2 FANCC_uc004avi.... Hybrid_Cap... view
FANCM p.L367S 14 45623172 45623172 LN229_CENTRAL_N... 37 Missense_Mutation SNP T C uc001wwd.3 FANCM_uc001wwc.... Hybrid_Cap... view
FBN1 p.N1650I 15 48756212 48756212 LN229_CENTRAL_N... 37 Missense_Mutation SNP T A uc001zwx.1 FBN1_uc010beo.1... Hybrid_Cap... view
FBN2 p.H2694Q 5 127599227 127599227 LN229_CENTRAL_N... 37 Missense_Mutation SNP G C uc003kuu.2 Hybrid_Cap... view
FGFR3 4 1809128 1809129 LN229_CENTRAL_N... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 LN229_CENTRAL_N... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLT1 p.P143S 13 29012444 29012444 LN229_CENTRAL_N... 37 Missense_Mutation SNP G A uc001usb.3 FLT1_uc010aar.1... Hybrid_Cap... view
FMN2 p.D182N 1 240255953 240255953 LN229_CENTRAL_N... 37 Missense_Mutation SNP G A uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap... view
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 LN229_CENTRAL_N... 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FZD1 p.93_94insP 7 90894459 90894460 LN229_CENTRAL_N... 37 In_Frame_Ins Ins - CCG uc003ula.2 Hybrid_Cap...
GLTSCR1 p.D905N 19 48197801 48197801 LN229_CENTRAL_N... 37 Missense_Mutation SNP G A uc002phh.3 GLTSCR1_uc002ph... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 LN229_CENTRAL_N... 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 LN229_CENTRAL_N... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIA3 p.K488N X 122538729 122538729 LN229_CENTRAL_N... 37 Missense_Mutation SNP A C uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 LN229_CENTRAL_N... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HNF1A 12 121434630 121434631 LN229_CENTRAL_N... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 LN229_CENTRAL_N... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITIH5L p.V760L X 54784229 54784229 LN229_CENTRAL_N... 37 Missense_Mutation SNP C G uc004dtj.2 Hybrid_Cap... view
ITPR1 p.A1886T 3 4810269 4810269 LN229_CENTRAL_N... 37 Missense_Mutation SNP G A uc003bqa.2 ITPR1_uc010hca.... Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 LN229_CENTRAL_N... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KIAA2022 p.G766E X 73962095 73962095 LN229_CENTRAL_N... 37 Missense_Mutation SNP C T uc004eby.2 Hybrid_Cap... view
KLK7 19 51480672 51480675 LN229_CENTRAL_N... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LIFR p.P1060A 5 38481813 38481813 LN229_CENTRAL_N... 37 Missense_Mutation SNP G C uc010ive.1 LIFR_uc003jli.2... Hybrid_Cap... view
LRP1 p.T3950I 12 57600514 57600514 LN229_CENTRAL_N... 37 Missense_Mutation SNP C T uc001snd.2 Hybrid_Cap... view
LRP1B p.H283F 2 141986754 141986755 LN229_CENTRAL_N... 37 Missense_Mutation DNP TG AA uc002tvj.1 LRP1B_uc010fnl.... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 LN229_CENTRAL_N... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 LN229_CENTRAL_N... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 LN229_CENTRAL_N... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K2 p.Y277C 2 128081486 128081486 LN229_CENTRAL_N... 37 Missense_Mutation SNP T C uc002toj.1 MAP3K2_uc010flz... Hybrid_Cap... view
MAP3K9 p.L194R 14 71267623 71267623 LN229_CENTRAL_N... 37 Missense_Mutation SNP A C uc001xml.2 MAP3K9_uc001xmm... Hybrid_Cap... view
MFSD2A p.E538D 1 40435222 40435222 LN229_CENTRAL_N... 37 Missense_Mutation SNP G C uc001cev.2 MFSD2A_uc001ceu... Hybrid_Cap... view
MTOR 1 11190898 11190898 LN229_CENTRAL_N... 37 Intron SNP C T uc001asd.2 MTOR_uc001asc.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 LN229_CENTRAL_N... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 LN229_CENTRAL_N... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA1 p.M1209V 2 24964974 24964974 LN229_CENTRAL_N... 37 Missense_Mutation SNP A G uc002rfk.2 NCOA1_uc010eye.... Hybrid_Cap... view
NCOA3 20 46282339 46282340 LN229_CENTRAL_N... 37 3'UTR Ins - AT uc002xtk.2 NCOA3_uc002xtl.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 LN229_CENTRAL_N... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NIPBL p.K1467E 5 37008803 37008803 LN229_CENTRAL_N... 37 Missense_Mutation SNP A G uc003jkl.3 NIPBL_uc003jkk.... Hybrid_Cap... view
NPR1 1 153665919 153665920 LN229_CENTRAL_N... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 LN229_CENTRAL_N... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NYNRIN p.G1402E 14 24885160 24885160 LN229_CENTRAL_N... 37 Missense_Mutation SNP G A uc001wpf.3 Hybrid_Cap... view
ODZ1 p.D808Y X 123695533 123695533 LN229_CENTRAL_N... 37 Missense_Mutation SNP C A uc010nqy.2 ODZ1_uc011muj.1... Hybrid_Cap... view
PAPPA p.G943R 9 119028230 119028230 LN229_CENTRAL_N... 37 Missense_Mutation SNP G A uc004bjn.2 PAPPA_uc011lxp.... Hybrid_Cap... view
PARP1 p.A367D 1 226570796 226570796 LN229_CENTRAL_N... 37 Missense_Mutation SNP G T uc001hqd.3 Hybrid_Cap... view
PATZ1 p.C497Y 22 31731695 31731695 LN229_CENTRAL_N... 37 Missense_Mutation SNP C T uc003akq.2 PATZ1_uc003akp.... Hybrid_Cap... view
PAX3 2 223158653 223158653 LN229_CENTRAL_N... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PCM1 8 17813228 17813229 LN229_CENTRAL_N... 37 Intron Ins - TA rs112321864 uc003wyi.3 PCM1_uc011kyh.1... Hybrid_Cap...
PDE4DIP p.Q1665fs 1 144873963 144873963 LN229_CENTRAL_N... 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.G996A 1 144886247 144886247 LN229_CENTRAL_N... 37 Missense_Mutation SNP C G uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PIK3R1 5 67591381 67591381 LN229_CENTRAL_N... 37 Intron SNP G T uc003jva.2 PIK3R1_uc003jvb... Hybrid_Cap... view
PIM2 p.D127H X 48772513 48772513 LN229_CENTRAL_N... 37 Missense_Mutation SNP C G uc004dls.2 Hybrid_Cap... view
PLD1 p.I706_splice 3 171392405 171392405 LN229_CENTRAL_N... 37 Splice_Site_SNP SNP T A uc003fhs.2 PLD1_uc003fht.2... Hybrid_Cap... view
PRAME p.V27M 22 22893454 22893454 LN229_CENTRAL_N... 37 Missense_Mutation SNP C T uc002zwf.2 LOC96610_uc011a... Hybrid_Cap... view
PRKAA1 p.P465A 5 40764703 40764703 LN229_CENTRAL_N... 37 Missense_Mutation SNP G C uc003jmb.2 PRKAA1_uc003jmc... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 LN229_CENTRAL_N... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKX p.Y336D X 3530312 3530312 LN229_CENTRAL_N... 37 Missense_Mutation SNP A C uc010nde.2 Hybrid_Cap... view
PTPN11 p.A72S 12 112888198 112888198 LN229_CENTRAL_N... 37 Missense_Mutation SNP G T uc001ttx.2 PTPN11_uc001ttw... Hybrid_Cap... view
PXDN 2 1657360 1657360 LN229_CENTRAL_N... 37 Intron SNP C T uc002qxa.2 PXDN_uc002qxb.1... Hybrid_Cap... view
RAD21 p.Q132* 8 117870678 117870678 LN229_CENTRAL_N... 37 Nonsense_Mutation SNP G A uc003yod.2 Hybrid_Cap... view
RARG 12 53607064 53607064 LN229_CENTRAL_N... 37 Intron Del A - uc001sce.2 RARG_uc001scd.2... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 LN229_CENTRAL_N... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RFC4 p.S320C 3 186507968 186507968 LN229_CENTRAL_N... 37 Missense_Mutation SNP G C uc003fqz.2 RFC4_uc011bsc.1... Hybrid_Cap... view
ROCK2 p.Q154_splice 2 11389785 11389785 LN229_CENTRAL_N... 37 Splice_Site_SNP SNP A G uc002rbd.1 Hybrid_Cap... view
RUNX1T1 8 93017304 93017304 LN229_CENTRAL_N... 37 Intron SNP A G uc011lgi.1 RUNX1T1_uc003yf... Hybrid_Cap... view
SKP2 p.N91D 5 36153135 36153135 LN229_CENTRAL_N... 37 Missense_Mutation SNP A G uc003jkc.1 SKP2_uc011cou.1... Hybrid_Cap... view
SORL1 11 121500400 121500401 LN229_CENTRAL_N... 37 3'UTR Ins - A rs73020651 uc001pxx.2 SORL1_uc010rzp.... Hybrid_Cap...
STAG3 p.L727P 7 99798934 99798934 LN229_CENTRAL_N... 37 Missense_Mutation SNP T C uc003utx.1 STAG3_uc010lgs.... Hybrid_Cap... view
TCF21 6 134210498 134210499 LN229_CENTRAL_N... 37 5'UTR Del TC - uc003qei.3 TCF21_uc003qej.... Hybrid_Cap...
TEC 4 48139307 48139310 LN229_CENTRAL_N... 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TIAM1 p.S224R 21 32638617 32638617 LN229_CENTRAL_N... 37 Missense_Mutation SNP G C uc002yow.1 TIAM1_uc011adk.... Hybrid_Cap... view
TLK1 2 171850178 171850179 LN229_CENTRAL_N... 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TLR9 p.M489I 3 52257156 52257156 LN229_CENTRAL_N... 37 Missense_Mutation SNP C A uc003ddb.2 TLR9_uc003dda.1... Hybrid_Cap... view
TNRC6B p.Q1328del 22 40697177 40697179 LN229_CENTRAL_N... 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TNRC6B p.A1635_splice 22 40711512 40711512 LN229_CENTRAL_N... 37 Splice_Site_SNP SNP G A uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap... view
TP53 p.P98L 17 7579394 7579394 LN229_CENTRAL_N... 37 Missense_Mutation SNP G A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIO p.G2803S 5 14502762 14502762 LN229_CENTRAL_N... 37 Missense_Mutation SNP G A uc003jff.2 TRIO_uc003jfg.2... Hybrid_Cap... view
TRPM8 p.I290V 2 234854668 234854668 LN229_CENTRAL_N... 37 Missense_Mutation SNP A G uc002vvh.2 TRPM8_uc010fyj.... Hybrid_Cap... view
USP6 p.N1337D 17 5074936 5074936 LN229_CENTRAL_N... 37 Missense_Mutation SNP A G uc002gau.1 USP6_uc002gav.1... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 LN229_CENTRAL_N... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
ZAP70 2 98351655 98351655 LN229_CENTRAL_N... 37 Intron Del G - uc002syd.1 ZAP70_uc010yvf.... Hybrid_Cap...