Annotation Summary for Cell Line: LP-1  

Cell line primary name: LP-1
Cell line aliases:
Gender: F
Site Primary: haematopoietic_and_lymphoid_tissue
Histology: lymphoid_neoplasm
Hist Subtype1: plasma_cell_myeloma
Notes:
Source: DSMZ
Expression arrays: SILOS_p_NCLE_RNA9_HG-U133_Plus_2_G01_523518
SNP arrays: MISTS_p_NCLE_DNAAffy11_GenomeWideSNP_6_E07_578286
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in LP-1

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ACACA 17 35766564 35766564 LP1_HAEMATOPOIE... 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ACVRL1 p.R386H 12 52309928 52309928 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP G A uc001rzj.2 ACVRL1_uc001rzk... Hybrid_Cap... view
ADAM12 10 127705700 127705700 LP1_HAEMATOPOIE... 37 3'UTR SNP C T uc001ljk.2 ADAM12_uc010qul... Hybrid_Cap... view
ADAM17 2 9630245 9630245 LP1_HAEMATOPOIE... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 LP1_HAEMATOPOIE... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAM32 p.E253* 8 39022639 39022639 LP1_HAEMATOPOIE... 37 Nonsense_Mutation SNP G T uc003xmt.3 ADAM32_uc011lch... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 LP1_HAEMATOPOIE... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK1 4 113347609 113347610 LP1_HAEMATOPOIE... 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
BLNK p.P98P 10 97987233 97987233 LP1_HAEMATOPOIE... 37 Silent SNP C T uc001kls.3 BLNK_uc001kme.3... Hybrid_Cap... view
BMP2K p.QQQQ482del 4 79792137 79792148 LP1_HAEMATOPOIE... 37 In_Frame_Del Del CAGCA... - rs17855588 uc003hlk.2 BMP2K_uc010ijl.... Hybrid_Cap...
CABC1 p.A413T 1 227171536 227171536 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP G A uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap... view
CARD10 p.A233_splice 22 37911979 37911979 LP1_HAEMATOPOIE... 37 Splice_Site_SNP SNP C T uc003asx.1 CARD10_uc003ast... Hybrid_Cap... view
CCDC50 3 191109582 191109582 LP1_HAEMATOPOIE... 37 3'UTR SNP C T uc003fsv.2 CCDC50_uc003fsw... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 LP1_HAEMATOPOIE... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 LP1_HAEMATOPOIE... 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CTNNB1 3 41278266 41278266 LP1_HAEMATOPOIE... 37 Intron SNP C T uc010hia.1 CTNNB1_uc003ckp... Hybrid_Cap... view
CXCL12 10 44873992 44873993 LP1_HAEMATOPOIE... 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
CYP27B1 p.G204R 12 58158974 58158974 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP C G uc001spz.1 CYP27B1_uc001sq... Hybrid_Cap... view
DDR2 1 162750211 162750212 LP1_HAEMATOPOIE... 37 3'UTR Del TT - uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap...
DNMT1 p.K307E 19 10274009 10274009 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP T C uc010xlc.1 DNMT1_uc002mng.... Hybrid_Cap... view
DOCK3 p.R1623W 3 51395491 51395491 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP C T uc011bds.1 Hybrid_Cap... view
DYRK1A 21 38884966 38884967 LP1_HAEMATOPOIE... 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EDN1 6 12290729 12290729 LP1_HAEMATOPOIE... 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EIF4E 4 99808137 99808141 LP1_HAEMATOPOIE... 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
EML4 p.E627E 2 42530568 42530568 LP1_HAEMATOPOIE... 37 Silent SNP A G uc002rsi.2 EML4_uc010fap.2... Hybrid_Cap... view
EP300 22 41574970 41574972 LP1_HAEMATOPOIE... 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA6 3 97367230 97367231 LP1_HAEMATOPOIE... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ETV1 7 14028708 14028708 LP1_HAEMATOPOIE... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 LP1_HAEMATOPOIE... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 LP1_HAEMATOPOIE... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 LP1_HAEMATOPOIE... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 LP1_HAEMATOPOIE... 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GAK p.V640A 4 870933 870933 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP A G uc003gbm.3 GAK_uc003gbn.3_... Hybrid_Cap... view
GRIA3 X 122318386 122318387 LP1_HAEMATOPOIE... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 LP1_HAEMATOPOIE... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 LP1_HAEMATOPOIE... 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
IGF1R 15 99192755 99192762 LP1_HAEMATOPOIE... 37 5'UTR Del TTTTT... - uc002bul.2 IGF1R_uc010urq.... Hybrid_Cap...
ILK 11 6630029 6630029 LP1_HAEMATOPOIE... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
KALRN 3 124438412 124438412 LP1_HAEMATOPOIE... 37 3'UTR SNP C T uc003ehg.2 KALRN_uc003ehk.... Hybrid_Cap... view
KDM6A p.Q593* X 44922760 44922760 LP1_HAEMATOPOIE... 37 Nonsense_Mutation SNP C T uc011mkz.1 KDM6A_uc010nhk.... Hybrid_Cap... view
KDM6A X 44970788 44970788 LP1_HAEMATOPOIE... 37 3'UTR SNP G A uc011mkz.1 KDM6A_uc004dge.... Hybrid_Cap... view
KLK7 19 51480672 51480675 LP1_HAEMATOPOIE... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LETM2 8 38265796 38265798 LP1_HAEMATOPOIE... 37 3'UTR Del ACT - uc003xlm.1 LETM2_uc003xll.... Hybrid_Cap...
LRGUK p.E88* 7 133812381 133812382 LP1_HAEMATOPOIE... 37 Nonsense_Mutation DNP CG AT uc003vrm.1 Hybrid_Cap...
LRP1B p.H1268R 2 141643868 141643868 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP T C uc002tvj.1 LRP1B_uc010fnl.... Hybrid_Cap... view
MAF 16 79628537 79628537 LP1_HAEMATOPOIE... 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 LP1_HAEMATOPOIE... 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 LP1_HAEMATOPOIE... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K6 17 67516272 67516272 LP1_HAEMATOPOIE... 37 Intron SNP C G uc002jij.2 MAP2K6_uc002jii... Hybrid_Cap... view
MAP3K14 p.R218_splice 17 43364293 43364294 LP1_HAEMATOPOIE... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K4 p.A1199del 6 161519351 161519353 LP1_HAEMATOPOIE... 37 In_Frame_Del Del CTG - uc003qtn.2 MAP3K4_uc010kkc... Hybrid_Cap...
MCM3APAS 21 47671275 47671276 LP1_HAEMATOPOIE... 37 3'UTR Ins - AAT rs67797185 uc002zin.2 MCM3APAS_uc002z... Hybrid_Cap...
MDM4 p.I19M 1 204494703 204494703 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP C G uc001hba.2 MDM4_uc001hbd.1... Hybrid_Cap... view
MED13L p.H375R 12 116452965 116452965 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP T C uc001tvw.2 Hybrid_Cap... view
MMP2 p.P506S 16 55530881 55530881 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP C T uc002ehz.3 MMP2_uc010vhd.1... Hybrid_Cap... view
MSH3 p.PPA66del 5 79950742 79950750 LP1_HAEMATOPOIE... 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
NBN p.W632* 8 90960070 90960070 LP1_HAEMATOPOIE... 37 Nonsense_Mutation SNP C T uc003yej.1 NBN_uc003yei.1_... Hybrid_Cap... view
NCAM1 11 112832307 112832308 LP1_HAEMATOPOIE... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 LP1_HAEMATOPOIE... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279864 46279866 LP1_HAEMATOPOIE... 37 In_Frame_Del Del CAA - rs1132443;rs28529067 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 LP1_HAEMATOPOIE... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFATC1 p.A453A 18 77193711 77193711 LP1_HAEMATOPOIE... 37 Silent SNP G A uc010xfg.1 NFATC1_uc002lnc... Hybrid_Cap... view
NR1H2 p.176_177insQ 19 50881822 50881823 LP1_HAEMATOPOIE... 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NTRK2 p.A11P 9 87285694 87285694 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP G C rs78936193 uc004anz.1 NTRK2_uc004anv.... Hybrid_Cap... view
NUDT11 X 51234522 51234522 LP1_HAEMATOPOIE... 37 3'UTR SNP C T uc010njt.2 Hybrid_Cap... view
PDGFB 22 39636899 39636900 LP1_HAEMATOPOIE... 37 Intron Ins - TCTC rs72014707 uc003axf.2 PDGFB_uc003axe.... Hybrid_Cap...
PDGFRA 4 55131002 55131002 LP1_HAEMATOPOIE... 37 Intron Del A - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PDK4 p.R166C 7 95222105 95222105 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP G A uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap... view
PHF3 p.S427R 6 64394904 64394904 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP T A uc003pep.1 PHF3_uc010kaf.1... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 LP1_HAEMATOPOIE... 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3R1 5 67586601 67586601 LP1_HAEMATOPOIE... 37 Intron SNP T A uc003jva.2 PIK3R1_uc003jvb... Hybrid_Cap... view
PIP5K1A p.H198Q 1 151205134 151205134 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP T A uc001exj.2 PIP5K1A_uc001ex... Hybrid_Cap... view
PML 15 74328011 74328011 LP1_HAEMATOPOIE... 37 Intron SNP C T uc002awv.2 PML_uc002awm.2_... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 LP1_HAEMATOPOIE... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG1 10 53227690 53227690 LP1_HAEMATOPOIE... 37 Intron SNP A G uc001jjo.2 PRKG1_uc001jjm.... Hybrid_Cap... view
PTPRT p.R1370C 20 40713407 40713407 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP G A uc010ggj.2 PTPRT_uc002xkg.... Hybrid_Cap... view
RAPGEF2 4 160189224 160189224 LP1_HAEMATOPOIE... 37 5'UTR SNP A T uc003iqg.3 Hybrid_Cap... view
RBBP8 p.G354fs 18 20572852 20572853 LP1_HAEMATOPOIE... 37 Frame_Shift_Ins Ins - A uc002kua.2 RBBP8_uc002ktw.... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 LP1_HAEMATOPOIE... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RPS6KA5 14 91360733 91360734 LP1_HAEMATOPOIE... 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
SCYL3 1 169822637 169822637 LP1_HAEMATOPOIE... 37 3'UTR SNP T C uc001ggs.2 SCYL3_uc010plw.... Hybrid_Cap... view
SPRY2 p.C186Y 13 80911284 80911284 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP C T uc001vli.2 SPRY2_uc001vlj.... Hybrid_Cap... view
STIL p.E358K 1 47753284 47753284 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP C T uc001crd.1 TAL1_uc001crb.1... Hybrid_Cap... view
SULF2 p.T453A 20 46305261 46305261 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP T C uc002xto.2 SULF2_uc002xtr.... Hybrid_Cap... view
TEC 4 48139307 48139310 LP1_HAEMATOPOIE... 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TLK1 2 171850195 171850196 LP1_HAEMATOPOIE... 37 3'UTR Ins - AG uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TNFRSF12A 16 3071998 3071998 LP1_HAEMATOPOIE... 37 3'UTR SNP A G uc002csv.3 TNFRSF12A_uc002... Hybrid_Cap... view
TNRC6B p.Q1328del 22 40697177 40697179 LP1_HAEMATOPOIE... 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TP53 p.E286K 17 7577082 7577082 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP C T uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP53BP1 15 43699541 43699541 LP1_HAEMATOPOIE... 37 3'UTR SNP C A uc001zrr.3 TP53BP1_uc010ud... Hybrid_Cap... view
TRRAP p.R2124C 7 98557015 98557015 LP1_HAEMATOPOIE... 37 Missense_Mutation SNP C T uc003upp.2 TRRAP_uc011kis.... Hybrid_Cap... view
TSC2 16 2138671 2138672 LP1_HAEMATOPOIE... 37 3'UTR Del AA - uc002con.2 TSC2_uc010bsd.2... Hybrid_Cap...
TTBK1 p.E771del 6 43250726 43250728 LP1_HAEMATOPOIE... 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
TTN p.E10172del 2 179542390 179542392 LP1_HAEMATOPOIE... 37 In_Frame_Del Del CTT - uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 LP1_HAEMATOPOIE... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
YWHAQ 2 9770589 9770590 LP1_HAEMATOPOIE... 37 5'UTR Ins - CGGGGC uc002qzw.2 YWHAQ_uc002qzx.... Hybrid_Cap...