Annotation Summary for Cell Line: LXF-289  

Cell line primary name: LXF-289
Cell line aliases:
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: adenocarcinoma
Notes:
Source: DSMZ
Expression arrays: SILOS_p_NCLE_RNA9_HG-U133_Plus_2_G02_523642
SNP arrays: AWASH_p_NCLE_DNAAffy10_GenomeWideSNP_6_G10_542940
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in LXF-289

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ACVR2A p.E305K 2 148676112 148676112 LXF289_LUNG 37 Missense_Mutation SNP G A uc002twg.2 ACVR2A_uc010zbn... Hybrid_Cap... view
ADAM28 8 24211994 24211997 LXF289_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AFF3 p.S889G 2 100203617 100203617 LXF289_LUNG 37 Missense_Mutation SNP T C uc002taf.2 AFF3_uc002tag.2... Hybrid_Cap... view
AGAP2 p.T647N 12 58125605 58125605 LXF289_LUNG 37 Missense_Mutation SNP G T uc001spq.2 AGAP2_uc001spp.... Hybrid_Cap... view
AKAP9 p.1335_1336insQ 7 91652178 91652179 LXF289_LUNG 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK1 4 113347609 113347610 LXF289_LUNG 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 LXF289_LUNG 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ATM p.E632Q 11 108123635 108123635 LXF289_LUNG 37 Missense_Mutation SNP G C uc001pkb.1 ATM_uc009yxr.1_... Hybrid_Cap... view
BAI3 p.K1056T 6 70042879 70042879 LXF289_LUNG 37 Missense_Mutation SNP A C uc003pev.3 BAI3_uc010kak.2... Hybrid_Cap... view
BMPR2 p.Q495E 2 203417508 203417508 LXF289_LUNG 37 Missense_Mutation SNP C G uc002uzf.3 BMPR2_uc010ftr.... Hybrid_Cap... view
BRD2 p.E695V 6 32947742 32947742 LXF289_LUNG 37 Missense_Mutation SNP A T uc010juh.2 BRD2_uc003ocn.3... Hybrid_Cap... view
C15ORF55 p.P470Q 15 34647268 34647268 LXF289_LUNG 37 Missense_Mutation SNP C A uc010ucc.1 C15orf55_uc010u... Hybrid_Cap... view
CACNB2 10 18828721 18828722 LXF289_LUNG 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CAMK1G 1 209768310 209768310 LXF289_LUNG 37 5'UTR SNP A G uc001hhd.2 CAMK1G_uc001hhf... Hybrid_Cap... view
CARD10 p.KE272del 22 37906309 37906314 LXF289_LUNG 37 In_Frame_Del Del CTCCT... - uc003asx.1 CARD10_uc003ast... Hybrid_Cap...
CASP7 10 115485612 115485612 LXF289_LUNG 37 Intron SNP C T uc001lao.2 CASP7_uc001lam.... Hybrid_Cap... view
CD160 1 145696411 145696411 LXF289_LUNG 37 3'UTR SNP A G uc001eol.1 NBPF10_uc001emp... Hybrid_Cap... view
CDKN2A p.R128S 9 21971142 21971142 LXF289_LUNG 37 Missense_Mutation SNP G T uc003zpl.2 MTAP_uc003zpi.1... Hybrid_Cap... view
CEP110 p.S222F 9 123860707 123860707 LXF289_LUNG 37 Missense_Mutation SNP C T uc004bkx.1 CEP110_uc004bkw... Hybrid_Cap... view
CEP110 p.H235N 9 123860745 123860745 LXF289_LUNG 37 Missense_Mutation SNP C A uc004bkx.1 CEP110_uc004bkw... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 LXF289_LUNG 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHD1 p.C1176S 5 98209342 98209342 LXF289_LUNG 37 Missense_Mutation SNP A T uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap... view
CSNK1A1 p.T109A 5 148904640 148904640 LXF289_LUNG 37 Missense_Mutation SNP T C uc003lqw.1 CSNK1A1_uc011dc... Hybrid_Cap... view
CSNK1A1 5 148930660 148930660 LXF289_LUNG 37 5'UTR SNP G C rs11556830 uc003lqw.1 CSNK1A1_uc011dc... Hybrid_Cap... view
CTNNB1 p.T41A 3 41266124 41266124 LXF289_LUNG 37 Missense_Mutation SNP A G uc010hia.1 CTNNB1_uc003ckp... Hybrid_Cap... view
DDR2 p.H110R 1 162724557 162724557 LXF289_LUNG 37 Missense_Mutation SNP A G uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap... view
DGKB 7 14216441 14216442 LXF289_LUNG 37 Intron Ins - G rs17167945 uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap...
DLL1 6 170597264 170597264 LXF289_LUNG 37 Intron SNP C A uc003qxm.2 DLL1_uc011ehc.1... Hybrid_Cap... view
DRD2 p.L113V 11 113288807 113288807 LXF289_LUNG 37 Missense_Mutation SNP G C uc001pnz.2 DRD2_uc010rwv.1... Hybrid_Cap... view
DYRK4 p.R255_splice 12 4705452 4705452 LXF289_LUNG 37 Splice_Site_SNP SNP G T uc009zeh.1 DYRK4_uc001qmx.... Hybrid_Cap... view
EIF2AK3 p.R718T 2 88874848 88874848 LXF289_LUNG 37 Missense_Mutation SNP C G uc002stc.3 Hybrid_Cap... view
EIF4E 4 99808137 99808141 LXF289_LUNG 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
EIF4G1 3 184038322 184038322 LXF289_LUNG 37 Intron SNP G C uc010hxx.2 EIF4G1_uc003fno... Hybrid_Cap... view
ELN 7 73483249 73483249 LXF289_LUNG 37 3'UTR SNP A T uc003tzw.2 RFC2_uc011kfa.1... Hybrid_Cap... view
EP300 22 41574970 41574972 LXF289_LUNG 37 3'UTR Del GTA - rs76489032 uc003azl.3 Hybrid_Cap...
EPHA4 2 222290469 222290469 LXF289_LUNG 37 3'UTR SNP A T uc002vmq.2 EPHA4_uc002vmr.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 LXF289_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ERCC3 p.D60N 2 128051145 128051145 LXF289_LUNG 37 Missense_Mutation SNP C T uc002toh.1 ERCC3_uc002toe.... Hybrid_Cap... view
ERCC6 p.S1345L 10 50668447 50668447 LXF289_LUNG 37 Missense_Mutation SNP G A uc001jhs.3 ERCC6_uc009xod.... Hybrid_Cap... view
ETV1 7 14028708 14028708 LXF289_LUNG 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
EXT1 8 118811867 118811867 LXF289_LUNG 37 3'UTR SNP C A uc003yok.1 Hybrid_Cap... view
EXT2 p.L345P 11 44146530 44146530 LXF289_LUNG 37 Missense_Mutation SNP T C uc001mya.2 EXT2_uc010rfo.1... Hybrid_Cap... view
EXT2 p.I748V 11 44265823 44265823 LXF289_LUNG 37 Missense_Mutation SNP A G uc001mya.2 EXT2_uc010rfo.1... Hybrid_Cap... view
FASN 17 80036878 80036878 LXF289_LUNG 37 3'UTR SNP T C uc002kdu.2 FASN_uc002kdv.1... Hybrid_Cap... view
FBN1 p.S2482R 15 48717573 48717573 LXF289_LUNG 37 Missense_Mutation SNP G T uc001zwx.1 FBN1_uc010beo.1... Hybrid_Cap... view
FBN2 5 127664268 127664268 LXF289_LUNG 37 Intron SNP T C uc003kuu.2 FBN2_uc003kuv.2... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 LXF289_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 LXF289_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNB p.G1072S 3 58108907 58108907 LXF289_LUNG 37 Missense_Mutation SNP G A uc010hne.2 FLNB_uc003djj.2... Hybrid_Cap... view
FN1 2 216244182 216244185 LXF289_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GPR112 p.G2697C X 135477557 135477557 LXF289_LUNG 37 Missense_Mutation SNP G T uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap... view
GRIA3 X 122318386 122318387 LXF289_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRK4 p.E515K 4 3039236 3039236 LXF289_LUNG 37 Missense_Mutation SNP G A uc003ggn.1 GRK4_uc003ggo.1... Hybrid_Cap... view
GRK6 p.D85H 5 176859100 176859100 LXF289_LUNG 37 Missense_Mutation SNP G C uc011dfz.1 GRK6_uc003mgp.2... Hybrid_Cap... view
GTSE1 p.D671N 22 46725339 46725339 LXF289_LUNG 37 Missense_Mutation SNP G A uc011aqy.1 GTSE1_uc011aqz.... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 LXF289_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A 14 62213929 62213930 LXF289_LUNG 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HIPK2 p.S317I 7 139415884 139415884 LXF289_LUNG 37 Missense_Mutation SNP C A uc003vvf.3 HIPK2_uc003vvd.... Hybrid_Cap... view
HNF1A 12 121434630 121434631 LXF289_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 LXF289_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INHBA 7 41729122 41729122 LXF289_LUNG 37 3'UTR SNP T G uc003thq.2 INHBA_uc003thr.... Hybrid_Cap... view
KLK7 19 51480672 51480675 LXF289_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KTN1 p.E400K 14 56096792 56096792 LXF289_LUNG 37 Missense_Mutation SNP G A uc001xcb.2 KTN1_uc001xce.2... Hybrid_Cap... view
LCP1 p.P266L 13 46725156 46725156 LXF289_LUNG 37 Missense_Mutation SNP G A uc001vaz.3 LCP1_uc001vba.3... Hybrid_Cap... view
LRP1B p.R3597P 2 141128833 141128833 LXF289_LUNG 37 Missense_Mutation SNP C G uc002tvj.1 Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 LXF289_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 LXF289_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 LXF289_LUNG 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPK14 6 36076345 36076354 LXF289_LUNG 37 3'UTR Del GTGTG... - rs80147786 uc003olp.2 MAPK14_uc003olq... Hybrid_Cap...
MDM2 p.E150E 12 69218358 69218358 LXF289_LUNG 37 Silent SNP A G uc001sui.2 MDM2_uc009zri.2... Hybrid_Cap... view
MGA p.Q1067* 15 42005463 42005463 LXF289_LUNG 37 Nonsense_Mutation SNP C T uc010ucy.1 MGA_uc001zog.1_... Hybrid_Cap... view
MLL p.E2419K 11 118373862 118373862 LXF289_LUNG 37 Missense_Mutation SNP G A uc001ptb.2 MLL_uc001pta.2_... Hybrid_Cap... view
MLLT3 9 20346377 20346378 LXF289_LUNG 37 3'UTR Ins - A rs66943046 uc003zoe.2 MLLT3_uc011lne.... Hybrid_Cap...
MYST4 p.V1545I 10 76789215 76789215 LXF289_LUNG 37 Missense_Mutation SNP G A uc001jwn.1 MYST4_uc001jwo.... Hybrid_Cap... view
NAV3 p.A1750V 12 78571045 78571045 LXF289_LUNG 37 Missense_Mutation SNP C T uc001syp.2 NAV3_uc001syo.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 LXF289_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 LXF289_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NLRP3 p.L971M 1 247608023 247608023 LXF289_LUNG 37 Missense_Mutation SNP C A uc001icr.2 NLRP3_uc001ics.... Hybrid_Cap... view
NR1H2 p.176_177insQ 19 50881822 50881823 LXF289_LUNG 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PAPPA p.G829A 9 118997670 118997670 LXF289_LUNG 37 Missense_Mutation SNP G C uc004bjn.2 PAPPA_uc011lxp.... Hybrid_Cap... view
PAX3 2 223158653 223158653 LXF289_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PCDH15 p.R1298G 10 55600186 55600186 LXF289_LUNG 37 Missense_Mutation SNP G C uc010qhy.1 PCDH15_uc010qhq... Hybrid_Cap... view
PCDH15 p.P381T 10 55955622 55955622 LXF289_LUNG 37 Missense_Mutation SNP G T uc010qhy.1 PCDH15_uc010qhq... Hybrid_Cap... view
PDE4DIP p.Q1665fs 1 144873963 144873963 LXF289_LUNG 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.V486fs 1 144917828 144917828 LXF289_LUNG 37 Frame_Shift_Del Del A - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 LXF289_LUNG 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PLEKHA5 p.E63* 12 19285344 19285344 LXF289_LUNG 37 Nonsense_Mutation SNP G T uc010sie.1 PLEKHA5_uc001re... Hybrid_Cap... view
PLEKHA5 p.E1139Q 12 19512427 19512427 LXF289_LUNG 37 Missense_Mutation SNP G C uc010sie.1 PLEKHA5_uc001re... Hybrid_Cap... view
PPARG p.V478L 3 12475558 12475558 LXF289_LUNG 37 Missense_Mutation SNP G T uc003bwx.2 PPARG_uc003bwr.... Hybrid_Cap... view
PPP1R3A p.L1086R 7 113517890 113517890 LXF289_LUNG 37 Missense_Mutation SNP A C uc010ljy.1 Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 LXF289_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RAD21 p.K358R 8 117866572 117866572 LXF289_LUNG 37 Missense_Mutation SNP T C uc003yod.2 Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 LXF289_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
SEPT3 p.*359* 22 42392970 42392970 LXF289_LUNG 37 Silent SNP G A uc003bbr.3 WBP2NL_uc011ape... Hybrid_Cap... view
SLCO4A1 20 61303398 61303398 LXF289_LUNG 37 3'UTR SNP C A uc002ydb.1 SLCO4A1_uc002yd... Hybrid_Cap... view
SOS1 p.N233Y 2 39281778 39281778 LXF289_LUNG 37 Missense_Mutation SNP T A uc002rrk.3 SOS1_uc010ynr.1... Hybrid_Cap... view
SPEN p.R206L 1 16202909 16202909 LXF289_LUNG 37 Missense_Mutation SNP G T uc001axk.1 SPEN_uc010obp.1... Hybrid_Cap... view
STK25 2 242435659 242435662 LXF289_LUNG 37 Intron Del AAGG - rs3215138;rs75497042 uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap...
TIE1 1 43779725 43779726 LXF289_LUNG 37 Intron Del TG - uc001ciu.2 TIE1_uc010oke.1... Hybrid_Cap...
TLK2 p.L321F 17 60642491 60642491 LXF289_LUNG 37 Missense_Mutation SNP C T uc010ddp.2 TLK2_uc002izx.3... Hybrid_Cap... view
TOP2A p.S1337L 17 38548548 38548548 LXF289_LUNG 37 Missense_Mutation SNP G A uc002huq.2 Hybrid_Cap... view
TP53 p.R248W 17 7577539 7577539 LXF289_LUNG 37 Missense_Mutation SNP G A uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM33 1 114940211 114940212 LXF289_LUNG 37 3'UTR Ins - T rs66490349 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRPM6 p.I2000M 9 77339598 77339598 LXF289_LUNG 37 Missense_Mutation SNP T C uc004ajl.1 TRPM6_uc004ajk.... Hybrid_Cap... view
TRPS1 8 116635872 116635873 LXF289_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN p.A14555G 2 179474885 179474885 LXF289_LUNG 37 Missense_Mutation SNP G C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
UNC13C p.S423C 15 54306368 54306368 LXF289_LUNG 37 Missense_Mutation SNP C G uc002ack.2 Hybrid_Cap... view
UNC13C p.H536L 15 54306707 54306707 LXF289_LUNG 37 Missense_Mutation SNP A T uc002ack.2 Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 LXF289_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WNK1 12 1018101 1018101 LXF289_LUNG 37 3'UTR SNP C A uc001qio.3 WNK1_uc001qip.3... Hybrid_Cap... view
ZNF276 16 89805448 89805448 LXF289_LUNG 37 3'UTR SNP A G uc002fos.3 ZNF276_uc010ciq... Hybrid_Cap... view