Annotation Summary for Cell Line: MC116  

Cell line primary name: MC116
Cell line aliases:
Gender: M
Site Primary: haematopoietic_and_lymphoid_tissue
Histology: lymphoid_neoplasm
Hist Subtype1: B_cell_lymphoma_unspecified
Notes:
Source: ATCC
Expression arrays: CASED_p_NCLE_RNA4_HG-U133_Plus_2_A07_383728
SNP arrays: FASTS_p_NCLE_DNAAffy4_S_GenomeWideSNP_6_D11_335280
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in MC116

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 MC116_HAEMATOPO... 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM17 2 9630245 9630245 MC116_HAEMATOPO... 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 p.A15S 8 24151705 24151705 MC116_HAEMATOPO... 37 Missense_Mutation SNP G T uc003xdy.2 ADAM28_uc003xdx... Hybrid_Cap... view
ADAM28 8 24211994 24211997 MC116_HAEMATOPO... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 MC116_HAEMATOPO... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK1 4 113347609 113347610 MC116_HAEMATOPO... 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 MC116_HAEMATOPO... 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
BCL6 p.A587D 3 187443366 187443366 MC116_HAEMATOPO... 37 Missense_Mutation SNP G T uc003frp.3 BCL6_uc011bsf.1... Hybrid_Cap... view
BCL9 p.S655R 1 147091926 147091926 MC116_HAEMATOPO... 37 Missense_Mutation SNP C A uc001epq.2 BCL9_uc010ozr.1... Hybrid_Cap... view
BCR 22 23631813 23631814 MC116_HAEMATOPO... 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BMP4 14 54416601 54416602 MC116_HAEMATOPO... 37 3'UTR Ins - AT rs74495140;rs76335800 uc001xal.3 BMP4_uc010aoh.2... Hybrid_Cap...
BRSK2 11 1482094 1482094 MC116_HAEMATOPO... 37 3'UTR SNP G A uc001ltm.2 BRSK2_uc001lti.... Hybrid_Cap... view
BTG1 12 92537706 92537707 MC116_HAEMATOPO... 37 3'UTR Ins - T rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
CABC1 1 227171736 227171737 MC116_HAEMATOPO... 37 Intron Ins - T rs1574184 uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CACNB2 10 18828721 18828722 MC116_HAEMATOPO... 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CCND3 p.I290fs 6 41903683 41903689 MC116_HAEMATOPO... 37 Frame_Shift_Del Del GGTGT... - uc003orn.2 CCND3_uc003orp.... Hybrid_Cap...
CDK11B 1 1654066 1654068 MC116_HAEMATOPO... 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CDKL2 p.N457D 4 76521478 76521478 MC116_HAEMATOPO... 37 Missense_Mutation SNP T C uc011cbp.1 CDKL2_uc003hiq.... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 MC116_HAEMATOPO... 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHN1 p.E49A 2 175783262 175783262 MC116_HAEMATOPO... 37 Missense_Mutation SNP T G uc002uji.2 CHN1_uc010zeq.1... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 MC116_HAEMATOPO... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
COL14A1 p.R283R 8 121211777 121211777 MC116_HAEMATOPO... 37 Silent SNP T C uc003yox.2 COL14A1_uc003yo... Hybrid_Cap... view
CSNK1G3 5 122950255 122950255 MC116_HAEMATOPO... 37 3'UTR Del T - uc003ktl.2 CSNK1G3_uc003kt... Hybrid_Cap...
CTBP2 p.K974fs 10 126678123 126678123 MC116_HAEMATOPO... 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
DACH1 13 72014625 72014626 MC116_HAEMATOPO... 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DDR2 1 162750211 162750212 MC116_HAEMATOPO... 37 3'UTR Del TT - uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap...
DYRK1A 21 38884966 38884967 MC116_HAEMATOPO... 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EIF4E 4 99808137 99808141 MC116_HAEMATOPO... 37 Intron Del TTAAA - uc011ceb.1 EIF4E_uc011cea.... Hybrid_Cap...
EPHA5 p.S235Y 4 66467565 66467565 MC116_HAEMATOPO... 37 Missense_Mutation SNP G T uc011cah.1 EPHA5_uc003hcx.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 MC116_HAEMATOPO... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ERBB3 12 56487760 56487760 MC116_HAEMATOPO... 37 Intron SNP T C uc001sjh.2 ERBB3_uc009zoj.... Hybrid_Cap... view
ETV1 7 14028708 14028708 MC116_HAEMATOPO... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FASN 17 80036961 80036961 MC116_HAEMATOPO... 37 3'UTR SNP G C uc002kdu.2 FASN_uc002kdv.1... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 MC116_HAEMATOPO... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 MC116_HAEMATOPO... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FN1 2 216244182 216244185 MC116_HAEMATOPO... 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GOPC p.A215P 6 117896347 117896347 MC116_HAEMATOPO... 37 Missense_Mutation SNP C G uc003pxu.2 GOPC_uc003pxq.1... Hybrid_Cap... view
GOPC p.H134R 6 117900112 117900112 MC116_HAEMATOPO... 37 Missense_Mutation SNP T C uc003pxu.2 GOPC_uc003pxv.2... Hybrid_Cap... view
GPC3 X 132888207 132888208 MC116_HAEMATOPO... 37 Intron Ins - A uc010nrn.1 GPC3_uc004exd.1... Hybrid_Cap...
GRIA3 X 122318386 122318387 MC116_HAEMATOPO... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIK1 p.F708L 21 30949292 30949292 MC116_HAEMATOPO... 37 Missense_Mutation SNP A G uc011acs.1 GRIK1_uc002ynn.... Hybrid_Cap... view
GRIN2A p.V489L 16 9934825 9934825 MC116_HAEMATOPO... 37 Missense_Mutation SNP C G uc002czo.3 GRIN2A_uc010uym... Hybrid_Cap... view
GUCY1A2 p.G681V 11 106579280 106579280 MC116_HAEMATOPO... 37 Missense_Mutation SNP C A uc009yxn.1 GUCY1A2_uc001pj... Hybrid_Cap... view
HIF1A 14 62213929 62213930 MC116_HAEMATOPO... 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 MC116_HAEMATOPO... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
IL1RAP p.A61V 3 190322034 190322034 MC116_HAEMATOPO... 37 Missense_Mutation SNP C T uc003fsq.2 IL1RAP_uc003fsk... Hybrid_Cap... view
IL1RAP p.R277C 3 190345165 190345165 MC116_HAEMATOPO... 37 Missense_Mutation SNP C T uc003fsq.2 IL1RAP_uc003fsk... Hybrid_Cap... view
ILK 11 6630029 6630029 MC116_HAEMATOPO... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 MC116_HAEMATOPO... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
JAK2 p.P811T 9 5080680 5080680 MC116_HAEMATOPO... 37 Missense_Mutation SNP C A uc010mhm.2 JAK2_uc003ziw.2... Hybrid_Cap... view
KLK7 19 51480672 51480675 MC116_HAEMATOPO... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LETM2 8 38265796 38265798 MC116_HAEMATOPO... 37 3'UTR Del ACT - uc003xlm.1 LETM2_uc003xll.... Hybrid_Cap...
LRP1B p.C516W 2 141812689 141812689 MC116_HAEMATOPO... 37 Missense_Mutation SNP G C uc002tvj.1 LRP1B_uc010fnl.... Hybrid_Cap... view
LRRC7 p.A789G 1 70503987 70503987 MC116_HAEMATOPO... 37 Missense_Mutation SNP C G uc001dep.2 LRRC7_uc009wbg.... Hybrid_Cap... view
MAF 16 79628537 79628537 MC116_HAEMATOPO... 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 MC116_HAEMATOPO... 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 MC116_HAEMATOPO... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K1 15 66679649 66679650 MC116_HAEMATOPO... 37 5'UTR Ins - C rs67229745 uc010bhq.2 Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 MC116_HAEMATOPO... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 MC116_HAEMATOPO... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MARK1 p.I40N 1 220752763 220752763 MC116_HAEMATOPO... 37 Missense_Mutation SNP T A uc009xdw.2 MARK1_uc001hml.... Hybrid_Cap... view
MET p.L530V 7 116380966 116380966 MC116_HAEMATOPO... 37 Missense_Mutation SNP C G uc010lkh.2 MET_uc003vij.2_... Hybrid_Cap... view
NCAM1 11 112832307 112832308 MC116_HAEMATOPO... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 MC116_HAEMATOPO... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK2 p.N66K 1 211847754 211847754 MC116_HAEMATOPO... 37 Missense_Mutation SNP G T uc001hir.1 NEK2_uc001hiq.1... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 MC116_HAEMATOPO... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFATC1 18 77287653 77287654 MC116_HAEMATOPO... 37 3'UTR Del AA - uc010xfg.1 NFATC1_uc002lnd... Hybrid_Cap...
NPR1 1 153665919 153665920 MC116_HAEMATOPO... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 MC116_HAEMATOPO... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUMA1 p.Q1170P 11 71725040 71725040 MC116_HAEMATOPO... 37 Missense_Mutation SNP T G uc001orl.1 NUMA1_uc009ysw.... Hybrid_Cap... view
NUP214 9 134067556 134067557 MC116_HAEMATOPO... 37 Intron Ins - T rs66652901 uc004cag.2 NUP214_uc004cah... Hybrid_Cap...
PAPPA p.R408H 9 118950240 118950240 MC116_HAEMATOPO... 37 Missense_Mutation SNP G A uc004bjn.2 PAPPA_uc011lxp.... Hybrid_Cap... view
PAWR p.R189Q 12 80014938 80014938 MC116_HAEMATOPO... 37 Missense_Mutation SNP C T uc001syx.2 Hybrid_Cap... view
PAX3 2 223158653 223158653 MC116_HAEMATOPO... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAXIP1 p.L523M 7 154760344 154760344 MC116_HAEMATOPO... 37 Missense_Mutation SNP G T uc003wlp.2 PAXIP1_uc003wlq... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 MC116_HAEMATOPO... 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIKFYVE p.S1474F 2 209200825 209200825 MC116_HAEMATOPO... 37 Missense_Mutation SNP C T uc002vcz.2 Hybrid_Cap... view
PMS1 2 190670539 190670540 MC116_HAEMATOPO... 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PREX2 p.Q1234H 8 69033262 69033262 MC116_HAEMATOPO... 37 Missense_Mutation SNP G T uc003xxv.1 Hybrid_Cap... view
PRKCB 16 24231502 24231502 MC116_HAEMATOPO... 37 3'UTR SNP G A uc002dme.2 PRKCB_uc002dmd.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 MC116_HAEMATOPO... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTEN p.W111R 10 89692847 89692847 MC116_HAEMATOPO... 37 Missense_Mutation SNP T C uc001kfb.2 Hybrid_Cap... view
RAD50 p.C681F 5 131931337 131931337 MC116_HAEMATOPO... 37 Missense_Mutation SNP G T uc003kxi.2 RAD50_uc003kxh.... Hybrid_Cap... view
RAPGEF2 4 160189200 160189201 MC116_HAEMATOPO... 37 5'UTR Ins - T rs72011511 uc003iqg.3 Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 MC116_HAEMATOPO... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
ROBO2 p.Q474K 3 77607271 77607271 MC116_HAEMATOPO... 37 Missense_Mutation SNP C A uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap... view
RPS6KA5 14 91360733 91360734 MC116_HAEMATOPO... 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
RPS6KL1 14 75373626 75373627 MC116_HAEMATOPO... 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SMARCA4 p.EEQD1254del 19 11144179 11144190 MC116_HAEMATOPO... 37 In_Frame_Del Del GAGGA... - uc010dxo.2 SMARCA4_uc002mq... Hybrid_Cap...
SMG1 p.P1306S 16 18870915 18870915 MC116_HAEMATOPO... 37 Missense_Mutation SNP G A uc002dfm.2 SMG1_uc010bwb.2... Hybrid_Cap... view
SPRY2 13 80910832 80910832 MC116_HAEMATOPO... 37 3'UTR SNP T C uc001vli.2 SPRY2_uc001vlj.... Hybrid_Cap... view
STK17A p.R221* 7 43659292 43659292 MC116_HAEMATOPO... 37 Nonsense_Mutation SNP C T uc003tih.2 C7orf44_uc003ti... Hybrid_Cap... view
STK31 7 23872024 23872025 MC116_HAEMATOPO... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TLK1 2 171850178 171850179 MC116_HAEMATOPO... 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TP53 p.C238Y 17 7577568 7577568 MC116_HAEMATOPO... 37 Missense_Mutation SNP C T uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 MC116_HAEMATOPO... 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIM33 1 114940215 114940216 MC116_HAEMATOPO... 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRPS1 8 116635872 116635873 MC116_HAEMATOPO... 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTBK1 p.E771del 6 43250726 43250728 MC116_HAEMATOPO... 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
TTN 2 179391639 179391640 MC116_HAEMATOPO... 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 MC116_HAEMATOPO... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...