Annotation Summary for Cell Line: MCF7  

Cell line primary name: MCF7
Cell line aliases:
Gender: F
Site Primary: breast
Histology: carcinoma
Hist Subtype1: NS
Notes: Identical lines: MCF-7 and KPL-1 share high SNP identity
Source: ATCC
Expression arrays: MAKER_p_NCLE_RNA7_HG-U133_Plus_2_G05_454738
SNP arrays: PODIA_p_NCLE_DNAAffy7_GenomeWideSNP_6_B09_437556
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in MCF7

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 MCF7_BREAST 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACVR1 2 9630245 9630245 MCF7_BREAST 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAMTS18 p.P138A 16 77465275 77465275 MCF7_BREAST 37 Missense_Mutation SNP G C uc002ffc.3 ADAMTS18_uc002f... Hybrid_Cap... view
ADAMTS18 p.S102L 16 77465382 77465382 MCF7_BREAST 37 Missense_Mutation SNP G A uc002ffc.3 ADAMTS18_uc002f... Hybrid_Cap... view
ALPK1 4 113347609 113347610 MCF7_BREAST 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 MCF7_BREAST 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ARID1A 12 92537852 92537852 MCF7_BREAST 37 3'UTR SNP T C uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap... view
BCR p.I456T 22 23596073 23596073 MCF7_BREAST 37 Missense_Mutation SNP T C rs113693210 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap... view
C15ORF55 3 97367230 97367231 MCF7_BREAST 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
CACNB2 10 18828721 18828722 MCF7_BREAST 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CDC42BPA 14 64694202 64694203 MCF7_BREAST 37 3'UTR Ins - A uc001xgu.2 ESR2_uc001xgv.2... Hybrid_Cap...
CDK11B p.PPLPGAGIPPP939del 1 240370914 240370946 MCF7_BREAST 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
CLK1 2 201724746 201724746 MCF7_BREAST 37 Intron SNP A G uc010zhi.1 CLK1_uc002uwd.2... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 MCF7_BREAST 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CTBP2 p.K974fs 10 126678123 126678123 MCF7_BREAST 37 Frame_Shift_Del Del T - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
EIF2AK4 15 40284909 40284909 MCF7_BREAST 37 Intron SNP A T uc001zkm.1 EIF2AK4_uc010bb... Hybrid_Cap... view
EPHA5 p.L1009P 4 66189923 66189923 MCF7_BREAST 37 Missense_Mutation SNP A G uc011cah.1 EPHA5_uc003hcx.... Hybrid_Cap... view
EPS15 p.988_989insD 6 136913666 136913667 MCF7_BREAST 37 In_Frame_Ins Ins - GTC uc003qhc.2 MAP3K5_uc011edj... Hybrid_Cap...
ERBB4 p.Y1242C 2 212248542 212248542 MCF7_BREAST 37 Missense_Mutation SNP T C uc002veg.1 ERBB4_uc002veh.... Hybrid_Cap... view
ERCC6 p.V83I 10 50740764 50740764 MCF7_BREAST 37 Missense_Mutation SNP C T uc001jhs.3 PGBD3_uc009xoe.... Hybrid_Cap... view
FBN2 p.I1500N 5 127654666 127654666 MCF7_BREAST 37 Missense_Mutation SNP A T uc003kuu.2 Hybrid_Cap... view
FBN2 X 122318386 122318387 MCF7_BREAST 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GLI1 p.QQQ1272del 20 46279815 46279823 MCF7_BREAST 37 In_Frame_Del Del GCAGC... - uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
GPR112 p.R470_splice 12 26834804 26834805 MCF7_BREAST 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
GRIA3 1 153665919 153665920 MCF7_BREAST 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
GRIK1 p.R3990G 2 141093332 141093332 MCF7_BREAST 37 Missense_Mutation SNP T C uc002tvj.1 Hybrid_Cap... view
GUCY2C p.Y816fs 7 151945071 151945072 MCF7_BREAST 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
HERC2 p.Q767_splice 4 140651585 140651587 MCF7_BREAST 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
ILK 11 112832340 112832340 MCF7_BREAST 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
ILK 11 6630029 6630029 MCF7_BREAST 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.A1199del 6 161519351 161519353 MCF7_BREAST 37 In_Frame_Del Del CTG - uc003qtn.2 MAP3K4_uc010kkc... Hybrid_Cap...
LRRK2 p.Q1597* 9 8341851 8341851 MCF7_BREAST 37 Nonsense_Mutation SNP G A uc003zkk.2 PTPRD_uc003zkp.... Hybrid_Cap... view
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 MCF7_BREAST 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 7 116381122 116381122 MCF7_BREAST 37 Intron Del T - uc010lkh.2 MET_uc003vij.2_... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 MCF7_BREAST 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K13 p.D380N 3 185167815 185167815 MCF7_BREAST 37 Missense_Mutation SNP G A uc010hyf.2 MAP3K13_uc011br... Hybrid_Cap... view
MAP3K14 p.R218_splice 17 43364293 43364294 MCF7_BREAST 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K14 p.KLDPHL682del 22 36702074 36702091 MCF7_BREAST 37 In_Frame_Del Del GAGAT... - uc003apg.2 MYH9_uc003aph.1... Hybrid_Cap...
MECOM 3 168862826 168862826 MCF7_BREAST 37 Intron SNP C T uc011bpj.1 MECOM_uc003ffj.... Hybrid_Cap... view
MLL3 11 112832307 112832308 MCF7_BREAST 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
MLLT4 p.E545K 3 178936091 178936091 MCF7_BREAST 37 Missense_Mutation SNP G A rs104886003 uc003fjk.2 Hybrid_Cap... view
MMP1 p.A23795D 2 179431771 179431771 MCF7_BREAST 37 Missense_Mutation SNP G T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
MTCP1NB 2 39212889 39212889 MCF7_BREAST 37 3'UTR SNP T G uc002rrk.3 SOS1_uc002rrj.3... Hybrid_Cap... view
MYLK p.T151T 3 123457879 123457879 MCF7_BREAST 37 Silent SNP G A uc003ego.2 MYLK_uc011bjw.1... Hybrid_Cap... view
NLRP1 p.P242Q 17 5463291 5463291 MCF7_BREAST 37 Missense_Mutation SNP G T uc002gci.2 NLRP1_uc002gcg.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 MCF7_BREAST 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
TCERG1L p.E435fs 10 132915153 132915153 MCF7_BREAST 37 Frame_Shift_Del Del T - uc001lkp.2 TCERG1L_uc009ya... Hybrid_Cap...
TNIK p.G884V 3 170811698 170811698 MCF7_BREAST 37 Missense_Mutation SNP C A uc003fhh.2 TNIK_uc003fhi.2... Hybrid_Cap... view
TRIM33 1 114940211 114940212 MCF7_BREAST 37 3'UTR Ins - T rs66490349 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRPS1 8 116635872 116635873 MCF7_BREAST 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 MCF7_BREAST 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WNK2 p.L312Q 9 95993250 95993251 MCF7_BREAST 37 Missense_Mutation DNP TG AA uc004ati.1 WNK2_uc011lud.1... Hybrid_Cap...