Annotation Summary for Cell Line: MDA-MB-415  

Cell line primary name: MDA-MB-415
Cell line aliases:
Gender: F
Site Primary: breast
Histology: carcinoma
Hist Subtype1: NS
Notes:
Source: ATCC
Expression arrays: NIECE_p_NCLE_RNA3_HG-U133_Plus_2_H09_296174
SNP arrays: FASTS_p_NCLE_DNAAffy4_S_GenomeWideSNP_6_C09_335252
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in MDA-MB-415

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 MDAMB415_BREAST 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM29 p.L691del 4 175898744 175898746 MDAMB415_BREAST 37 In_Frame_Del Del TTA - uc003iuc.2 ADAM29_uc003iud... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 MDAMB415_BREAST 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALK p.P236R 2 29940524 29940524 MDAMB415_BREAST 37 Missense_Mutation SNP G C uc002rmy.2 Hybrid_Cap... view
BCR 22 23631813 23631814 MDAMB415_BREAST 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BRAF p.P74A 7 140549931 140549931 MDAMB415_BREAST 37 Missense_Mutation SNP G C uc003vwc.3 Hybrid_Cap... view
C15ORF2 p.S811F 15 24923446 24923446 MDAMB415_BREAST 37 Missense_Mutation SNP C T uc001ywo.2 Hybrid_Cap... view
CASP2 p.V230V 7 142991809 142991809 MDAMB415_BREAST 37 Silent SNP C T uc003wco.2 CASP2_uc003wcp.... Hybrid_Cap... view
CBL p.S854L 11 119170331 119170331 MDAMB415_BREAST 37 Missense_Mutation SNP C T uc001pwe.2 Hybrid_Cap... view
CD44 p.S717S 11 35250802 35250802 MDAMB415_BREAST 37 Silent SNP G A uc001mvu.2 CD44_uc001mvv.2... Hybrid_Cap... view
CDC42BPB p.D241H 14 103450063 103450063 MDAMB415_BREAST 37 Missense_Mutation SNP C G uc001ymi.1 Hybrid_Cap... view
CDH11 p.E375* 16 65016081 65016081 MDAMB415_BREAST 37 Nonsense_Mutation SNP C A uc002eoi.2 CDH11_uc010cdn.... Hybrid_Cap... view
CDH11 p.D794E 16 64981515 64981515 MDAMB415_BREAST 37 Missense_Mutation SNP G C uc002eoi.2 CDH11_uc010cdn.... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 MDAMB415_BREAST 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CHD9 p.D1171H 16 53281261 53281261 MDAMB415_BREAST 37 Missense_Mutation SNP G C uc002ehb.2 CHD9_uc002egy.2... Hybrid_Cap... view
CHRNA5 p.Q376E 15 78882859 78882859 MDAMB415_BREAST 37 Missense_Mutation SNP C G uc002bdy.2 CHRNA5_uc002bdz... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 MDAMB415_BREAST 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CSF1R p.Q970* 5 149433643 149433643 MDAMB415_BREAST 37 Nonsense_Mutation SNP G A uc003lrl.2 CSF1R_uc011dcd.... Hybrid_Cap... view
CSMD3 p.Y3505N 8 113249533 113249533 MDAMB415_BREAST 37 Missense_Mutation SNP A T uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
DGKG p.G193S 3 186002466 186002466 MDAMB415_BREAST 37 Missense_Mutation SNP C T uc003fqa.2 DGKG_uc003fqb.2... Hybrid_Cap... view
DST p.E994K 6 56500494 56500494 MDAMB415_BREAST 37 Missense_Mutation SNP C T uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
ERBB4 p.W638* 2 212522511 212522511 MDAMB415_BREAST 37 Nonsense_Mutation SNP C T uc002veg.1 ERBB4_uc002veh.... Hybrid_Cap... view
ERCC3 2 128047500 128047500 MDAMB415_BREAST 37 Intron SNP G A uc002toh.1 ERCC3_uc002toe.... Hybrid_Cap... view
FANCC p.E218K 9 97912239 97912239 MDAMB415_BREAST 37 Missense_Mutation SNP C T uc004avh.2 FANCC_uc004avi.... Hybrid_Cap... view
FGFR4 p.S773N 5 176524586 176524586 MDAMB415_BREAST 37 Missense_Mutation SNP G A uc003mfl.2 FGFR4_uc003mfm.... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 MDAMB415_BREAST 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 MDAMB415_BREAST 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 MDAMB415_BREAST 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HECW1 p.R339P 7 43482199 43482199 MDAMB415_BREAST 37 Missense_Mutation SNP G C uc003tid.1 HECW1_uc011kbi.... Hybrid_Cap... view
HERC2 p.Q2664* 15 28443545 28443545 MDAMB415_BREAST 37 Nonsense_Mutation SNP G A uc001zbj.2 HERC2_uc001zbk.... Hybrid_Cap... view
IKZF3 p.S197C 17 37947671 37947671 MDAMB415_BREAST 37 Missense_Mutation SNP G C uc002hsu.2 IKZF3_uc002htd.... Hybrid_Cap... view
ILK 11 6630029 6630029 MDAMB415_BREAST 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
IRAK4 p.H390R 12 44177508 44177508 MDAMB415_BREAST 37 Missense_Mutation SNP A G rs4251583 uc001rnu.3 IRAK4_uc001rnt.... Hybrid_Cap... view
ITGA10 1 145528358 145528358 MDAMB415_BREAST 37 Intron SNP G C uc001eoa.2 NBPF10_uc001emp... Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 MDAMB415_BREAST 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KALRN p.D1395N 3 124196179 124196179 MDAMB415_BREAST 37 Missense_Mutation SNP G A uc003ehg.2 KALRN_uc010hrv.... Hybrid_Cap... view
KIAA1409 p.Q821* 14 94053214 94053214 MDAMB415_BREAST 37 Nonsense_Mutation SNP C T uc001ybv.1 KIAA1409_uc001y... Hybrid_Cap... view
LRP1B p.P2342A 2 141356370 141356370 MDAMB415_BREAST 37 Missense_Mutation SNP G C uc002tvj.1 Hybrid_Cap... view
LRP2 p.G522R 2 170135883 170135883 MDAMB415_BREAST 37 Missense_Mutation SNP C G uc002ues.2 LRP2_uc010zdf.1... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 MDAMB415_BREAST 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K4 p.S291* 17 12028636 12028636 MDAMB415_BREAST 37 Nonsense_Mutation SNP C A uc002gnk.2 MAP2K4_uc002gnj... Hybrid_Cap... view
MAP3K1 p.R162fs 5 56152429 56152429 MDAMB415_BREAST 37 Frame_Shift_Del Del G - uc003jqw.3 Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 MDAMB415_BREAST 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K3 p.E29K 17 61710121 61710121 MDAMB415_BREAST 37 Missense_Mutation SNP G A uc002jbe.2 MAP3K3_uc002jbf... Hybrid_Cap... view
MECOM p.Q341* 3 168838955 168838955 MDAMB415_BREAST 37 Nonsense_Mutation SNP G A uc011bpj.1 MECOM_uc010hwk.... Hybrid_Cap... view
MLL3 p.E3716K 7 151859516 151859516 MDAMB415_BREAST 37 Missense_Mutation SNP C T uc003wla.2 MLL3_uc003wkz.2... Hybrid_Cap... view
MLLT10 p.G483A 10 21962675 21962675 MDAMB415_BREAST 37 Missense_Mutation SNP G C uc001iqs.2 MLLT10_uc001iqt... Hybrid_Cap... view
MYST4 p.E1104del 10 76781906 76781908 MDAMB415_BREAST 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NAV3 p.S1054* 12 78513137 78513137 MDAMB415_BREAST 37 Nonsense_Mutation SNP C G uc001syp.2 NAV3_uc001syo.2... Hybrid_Cap... view
NCAM1 11 112832276 112832277 MDAMB415_BREAST 37 5'UTR Ins - G uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 MDAMB415_BREAST 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279837 46279839 MDAMB415_BREAST 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 MDAMB415_BREAST 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 MDAMB415_BREAST 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 MDAMB415_BREAST 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
PAX3 p.I191M 2 223158899 223158899 MDAMB415_BREAST 37 Missense_Mutation SNP G C uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 MDAMB415_BREAST 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PKN2 p.E281K 1 89237418 89237418 MDAMB415_BREAST 37 Missense_Mutation SNP G A uc001dmn.2 PKN2_uc001dmm.1... Hybrid_Cap... view
PLK2 5 57750365 57750365 MDAMB415_BREAST 37 3'UTR SNP C T uc003jrn.2 Hybrid_Cap... view
PNCK X 152936857 152936857 MDAMB415_BREAST 37 Intron SNP G A uc011myu.1 PNCK_uc011myt.1... Hybrid_Cap... view
PPM1E p.E261Q 17 57043252 57043252 MDAMB415_BREAST 37 Missense_Mutation SNP G C uc002iwx.2 PPM1E_uc010ddd.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 MDAMB415_BREAST 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTEN p.C136Y 10 89692923 89692923 MDAMB415_BREAST 37 Missense_Mutation SNP G A uc001kfb.2 Hybrid_Cap... view
RASGRF2 p.G1167R 5 80513239 80513239 MDAMB415_BREAST 37 Missense_Mutation SNP G C uc003kha.1 RNU5E_uc011cto.... Hybrid_Cap... view
RASGRF2 p.R1183T 5 80513288 80513288 MDAMB415_BREAST 37 Missense_Mutation SNP G C uc003kha.1 RNU5E_uc011cto.... Hybrid_Cap... view
RICTOR p.E1349K 5 38949905 38949905 MDAMB415_BREAST 37 Missense_Mutation SNP C T uc003jlo.2 RICTOR_uc003jlp... Hybrid_Cap... view
ROCK1 p.S662L 18 18572799 18572799 MDAMB415_BREAST 37 Missense_Mutation SNP G A uc002kte.2 Hybrid_Cap... view
SLC22A15 p.L298L 1 116574152 116574152 MDAMB415_BREAST 37 Silent SNP C T uc001egb.3 SLC22A15_uc001e... Hybrid_Cap... view
SMG1 p.H875D 16 18881186 18881186 MDAMB415_BREAST 37 Missense_Mutation SNP G C uc002dfm.2 SMG1_uc010bwb.2... Hybrid_Cap... view
SSX1 X 48116655 48116655 MDAMB415_BREAST 37 Splice_Site_SNP SNP A T uc004djb.1 Hybrid_Cap... view
TEX14 p.R412P 17 56682458 56682458 MDAMB415_BREAST 37 Missense_Mutation SNP C G uc010dcz.1 TEX14_uc002iwr.... Hybrid_Cap... view
TP53 p.Y236C 17 7577574 7577574 MDAMB415_BREAST 37 Missense_Mutation SNP T C uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 MDAMB415_BREAST 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TTN p.P22889S 2 179434490 179434490 MDAMB415_BREAST 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
UBE3B 12 109947357 109947358 MDAMB415_BREAST 37 Intron Ins - T uc001top.2 UBE3B_uc001toq.... Hybrid_Cap...
URB2 p.L1057V 1 229773529 229773529 MDAMB415_BREAST 37 Missense_Mutation SNP C G uc001hts.1 URB2_uc009xfd.1... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 MDAMB415_BREAST 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
ZNF423 p.K931M 16 49670271 49670271 MDAMB415_BREAST 37 Missense_Mutation SNP T A uc002efs.2 ZNF423_uc010vgn... Hybrid_Cap... view