Annotation Summary for Cell Line: MDA-MB-468  

Cell line primary name: MDA-MB-468
Cell line aliases:
Gender: F
Site Primary: breast
Histology: carcinoma
Hist Subtype1: NS
Notes:
Source: ATCC
Expression arrays: PARES_p_NCLE_RNA_Redo_HG-U133_Plus_2_A02_257600
SNP arrays: LIMPS_p_NCLE_DNA2N_GenomeWideSNP_6_F07_246742
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in MDA-MB-468

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ADAM17 2 9630245 9630245 MDAMB468_BREAST 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 MDAMB468_BREAST 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 MDAMB468_BREAST 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 MDAMB468_BREAST 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
BCL2L11 p.R85T 2 111881576 111881576 MDAMB468_BREAST 37 Missense_Mutation SNP G C uc002tgv.1 BCL2L11_uc002tg... Hybrid_Cap... view
BLM p.D554V 15 91304264 91304264 MDAMB468_BREAST 37 Missense_Mutation SNP A T uc002bpr.2 BLM_uc010uqh.1_... Hybrid_Cap... view
BMP2K p.Q486del 4 79792083 79792085 MDAMB468_BREAST 37 In_Frame_Del Del CAG - uc003hlk.2 BMP2K_uc010ijl.... Hybrid_Cap...
CARS p.H147R 11 3062141 3062141 MDAMB468_BREAST 37 Missense_Mutation SNP T C uc001lxf.2 CARS_uc001lxe.2... Hybrid_Cap... view
CDKL2 p.T471I 4 76521435 76521435 MDAMB468_BREAST 37 Missense_Mutation SNP G A uc011cbp.1 CDKL2_uc003hiq.... Hybrid_Cap... view
CDKN2C 1 51436013 51436013 MDAMB468_BREAST 37 Intron SNP C A uc001csf.2 CDKN2C_uc001csg... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 MDAMB468_BREAST 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 MDAMB468_BREAST 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 MDAMB468_BREAST 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 MDAMB468_BREAST 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSNK1G1 p.K260fs 15 64497132 64497135 MDAMB468_BREAST 37 Frame_Shift_Del Del TCTT - uc002anh.1 CSNK1G1_uc002an... Hybrid_Cap...
CTBP2 p.Q175fs 10 126715804 126715805 MDAMB468_BREAST 37 Frame_Shift_Del Del CT - uc001lie.3 CTBP2_uc009yak.... Hybrid_Cap...
CYCS 7 25163255 25163255 MDAMB468_BREAST 37 3'UTR SNP G A uc003sxl.2 Hybrid_Cap... view
DDR2 p.V824A 1 162749939 162749939 MDAMB468_BREAST 37 Missense_Mutation SNP T C uc001gcf.2 DDR2_uc001gcg.2... Hybrid_Cap... view
DVL1 p.E138D 1 1277485 1277485 MDAMB468_BREAST 37 Missense_Mutation SNP C G uc001aer.3 DVL1_uc002quu.2... Hybrid_Cap... view
EDN1 6 12296150 12296151 MDAMB468_BREAST 37 Intron Ins - T rs66570617 uc003nae.3 EDN1_uc003nad.2... Hybrid_Cap...
EEF1D 8 144661906 144661907 MDAMB468_BREAST 37 3'UTR Ins - A uc003yyq.1 NAPRT1_uc003yym... Hybrid_Cap...
ELN p.G403D 7 73470658 73470658 MDAMB468_BREAST 37 Missense_Mutation SNP G A uc003tzw.2 RFC2_uc011kfa.1... Hybrid_Cap... view
EPHB6 p.176_177insS 7 142562051 142562052 MDAMB468_BREAST 37 In_Frame_Ins Ins - CAT rs72043374 uc011kst.1 EPHB6_uc011ksu.... Hybrid_Cap...
EPHB6 7 142568771 142568771 MDAMB468_BREAST 37 3'UTR Del C - uc011kst.1 EPHB6_uc011ksu.... Hybrid_Cap...
ERBB2 p.G152fs 17 37865585 37865585 MDAMB468_BREAST 37 Frame_Shift_Del Del G - uc002hso.2 ERBB2_uc002hsm.... Hybrid_Cap...
ETV1 7 14028708 14028708 MDAMB468_BREAST 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FANCA p.Q869* 16 89831471 89831471 MDAMB468_BREAST 37 Nonsense_Mutation SNP G A uc002fou.1 FANCA_uc010vpn.... Hybrid_Cap... view
FANCE p.G246del 6 35424008 35424010 MDAMB468_BREAST 37 In_Frame_Del Del GGA - rs78210100 uc003oko.1 FANCE_uc010jvw.... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 MDAMB468_BREAST 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLCN 17 17116847 17116847 MDAMB468_BREAST 37 3'UTR SNP C G uc002gra.3 PLD6_uc010cpn.2... Hybrid_Cap... view
FLI1 11 128638217 128638217 MDAMB468_BREAST 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FOXP1 3 71008341 71008342 MDAMB468_BREAST 37 3'UTR Ins - T rs11433724;rs114233617 uc003dol.2 FOXP1_uc003dom.... Hybrid_Cap...
GOPC p.Y462del 6 117884418 117884420 MDAMB468_BREAST 37 In_Frame_Del Del TAA - rs79419780 uc003pxu.2 GOPC_uc003pxq.1... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 MDAMB468_BREAST 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 MDAMB468_BREAST 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIN2B p.E531G 12 13768110 13768110 MDAMB468_BREAST 37 Missense_Mutation SNP T C uc001rbt.2 Hybrid_Cap... view
GRK1 p.Y315C 13 114325930 114325930 MDAMB468_BREAST 37 Missense_Mutation SNP A G uc010tkf.1 Hybrid_Cap... view
ILK 11 6630029 6630029 MDAMB468_BREAST 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INPP4B 4 143352508 143352508 MDAMB468_BREAST 37 5'UTR SNP A G uc003iix.3 INPP4B_uc003iiw... Hybrid_Cap... view
ITK 5 156607915 156607915 MDAMB468_BREAST 37 5'UTR SNP T G rs113811363 uc003lwo.1 Hybrid_Cap... view
JAZF1 7 27872323 27872323 MDAMB468_BREAST 37 3'UTR SNP T C uc003szn.2 JAZF1_uc003szm.... Hybrid_Cap... view
KLK7 19 51480672 51480675 MDAMB468_BREAST 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KTN1 p.E699Q 14 56107918 56107918 MDAMB468_BREAST 37 Missense_Mutation SNP G C uc001xcb.2 KTN1_uc001xce.2... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 MDAMB468_BREAST 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 MDAMB468_BREAST 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 MDAMB468_BREAST 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K4 p.A1199del 6 161519351 161519353 MDAMB468_BREAST 37 In_Frame_Del Del CTG - uc003qtn.2 MAP3K4_uc010kkc... Hybrid_Cap...
MAP3K5 6 136977434 136977434 MDAMB468_BREAST 37 Intron SNP A G uc003qhc.2 MAP3K5_uc011edj... Hybrid_Cap... view
MAP4K3 p.A163G 2 39559100 39559100 MDAMB468_BREAST 37 Missense_Mutation SNP G C uc002rro.2 MAP4K3_uc002rrp... Hybrid_Cap... view
MATK p.E222* 19 3783139 3783139 MDAMB468_BREAST 37 Nonsense_Mutation SNP C A uc002lyv.2 MATK_uc002lyt.2... Hybrid_Cap... view
MECOM 3 169381262 169381262 MDAMB468_BREAST 37 5'UTR SNP G C rs10581416 uc011bpj.1 MECOM_uc011bpk.... Hybrid_Cap... view
MELK p.G20V 9 36583624 36583624 MDAMB468_BREAST 37 Missense_Mutation SNP G T uc003zzn.2 MELK_uc011lpm.1... Hybrid_Cap... view
MLKL p.R449W 16 74708894 74708894 MDAMB468_BREAST 37 Missense_Mutation SNP G A uc002fdb.2 MLKL_uc002fdc.2... Hybrid_Cap... view
MLL3 p.Y816fs 7 151945071 151945072 MDAMB468_BREAST 37 Frame_Shift_Ins Ins - T uc003wla.2 Hybrid_Cap...
MN1 p.540_540Q>QQ 22 28194912 28194913 MDAMB468_BREAST 37 In_Frame_Ins Ins - TGC rs45520238 uc003adj.2 Hybrid_Cap...
MYO3B p.R1104W 2 171358315 171358315 MDAMB468_BREAST 37 Missense_Mutation SNP C T uc002ufy.2 MYO3B_uc002ufv.... Hybrid_Cap... view
MYST4 p.E1104del 10 76781906 76781908 MDAMB468_BREAST 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NCAM1 11 112832307 112832308 MDAMB468_BREAST 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 MDAMB468_BREAST 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279864 46279866 MDAMB468_BREAST 37 In_Frame_Del Del CAA - rs1132443;rs28529067 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEDD9 p.G569R 6 11190397 11190397 MDAMB468_BREAST 37 Missense_Mutation SNP C T uc003mzv.2 NEDD9_uc010joz.... Hybrid_Cap... view
NF1 p.Q1033R 17 29557385 29557385 MDAMB468_BREAST 37 Missense_Mutation SNP A G uc002hgg.2 NF1_uc002hgh.2_... Hybrid_Cap... view
NIN 14 51290090 51290090 MDAMB468_BREAST 37 Intron SNP T C uc001wyi.2 NIN_uc001wyj.2_... Hybrid_Cap... view
NOTCH4 p.15_16LL>L 6 32191659 32191661 MDAMB468_BREAST 37 In_Frame_Del Del AGC - uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881822 50881823 MDAMB468_BREAST 37 In_Frame_Ins Ins - CAG rs61751954;rs1052533 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUMA1 11 71718530 71718530 MDAMB468_BREAST 37 Intron Del T - uc001orl.1 NUMA1_uc001orj.... Hybrid_Cap...
OBSCN p.A2264E 1 228465491 228465491 MDAMB468_BREAST 37 Missense_Mutation SNP C A uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
OBSCN p.G7099R 1 228559774 228559774 MDAMB468_BREAST 37 Missense_Mutation SNP G A uc009xez.1 OBSCN_uc001hsr.... Hybrid_Cap... view
OMG p.W422L 17 29622085 29622085 MDAMB468_BREAST 37 Missense_Mutation SNP C A uc002hgj.2 NF1_uc002hgg.2_... Hybrid_Cap... view
PAX3 2 223066017 223066018 MDAMB468_BREAST 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PIK3C2A 11 17111198 17111199 MDAMB468_BREAST 37 3'UTR Del GT - uc001mmq.3 PIK3C2A_uc009yg... Hybrid_Cap...
PIK3C2B p.G1435S 1 204399144 204399144 MDAMB468_BREAST 37 Missense_Mutation SNP C T uc001haw.2 PIK3C2B_uc010pq... Hybrid_Cap... view
PLAG1 p.M361V 8 57079224 57079224 MDAMB468_BREAST 37 Missense_Mutation SNP T C uc003xsq.3 PLAG1_uc003xsr.... Hybrid_Cap... view
PMS1 2 190670539 190670540 MDAMB468_BREAST 37 Intron Ins - A rs3214425 uc002urh.3 PMS1_uc010zga.1... Hybrid_Cap...
PNCK X 152938180 152938183 MDAMB468_BREAST 37 Intron Del GGAA - uc011myu.1 PNCK_uc011myt.1... Hybrid_Cap...
POU5F1B p.C70fs 8 128428321 128428322 MDAMB468_BREAST 37 Frame_Shift_Ins Ins - G uc003ysf.2 LOC727677_uc003... Hybrid_Cap...
POU5F1B p.P339A 8 128429126 128429126 MDAMB468_BREAST 37 Missense_Mutation SNP C G uc003ysf.2 LOC727677_uc003... Hybrid_Cap... view
PRDM16 p.P937A 1 3334509 3334509 MDAMB468_BREAST 37 Missense_Mutation SNP C G uc001akf.2 PRDM16_uc001akc... Hybrid_Cap... view
PRKCZ 1 2116570 2116570 MDAMB468_BREAST 37 3'UTR SNP G A uc001aiq.2 PRKCZ_uc001air.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 MDAMB468_BREAST 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTEN p.V85_splice 10 89690847 89690847 MDAMB468_BREAST 37 Splice_Site_SNP SNP G T uc001kfb.2 Hybrid_Cap... view
RAPGEF2 4 160189200 160189201 MDAMB468_BREAST 37 5'UTR Ins - T rs72011511 uc003iqg.3 Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 MDAMB468_BREAST 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RNF130 p.R222M 5 179440089 179440089 MDAMB468_BREAST 37 Missense_Mutation SNP C A uc003mll.1 RNF130_uc003mlm... Hybrid_Cap... view
STK31 7 23872024 23872025 MDAMB468_BREAST 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TMEM123 11 102269398 102269398 MDAMB468_BREAST 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNRC6B p.Q1328del 22 40697177 40697179 MDAMB468_BREAST 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TRIM33 1 114940215 114940216 MDAMB468_BREAST 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TSSK6 19 19625333 19625333 MDAMB468_BREAST 37 3'UTR SNP T G uc002nmr.2 TSSK6_uc002nmq.... Hybrid_Cap... view
TTN p.P17703L 2 179455640 179455640 MDAMB468_BREAST 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.R15131G 2 179472320 179472320 MDAMB468_BREAST 37 Missense_Mutation SNP G C uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 MDAMB468_BREAST 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
ZFYVE9 p.F1090L 1 52761586 52761586 MDAMB468_BREAST 37 Missense_Mutation SNP C G uc001cto.2 ZFYVE9_uc001ctp... Hybrid_Cap... view