Annotation Summary for Cell Line: MFE-280  

Cell line primary name: MFE-280
Cell line aliases:
Gender: F
Site Primary: endometrium
Histology: carcinoma
Hist Subtype1: adenocarcinoma
Notes:
Source: DSMZ
Expression arrays: BRAKE_p_NCLE_RNA2_HG-U133_Plus_2_E10_241156
SNP arrays: LIMPS_p_NCLE_DNA2N_GenomeWideSNP_6_G09_246770
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in MFE-280

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 MFE280_ENDOMETR... 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ABCA3 p.S693L 16 2347515 2347515 MFE280_ENDOMETR... 37 Missense_Mutation SNP G A uc002cpy.1 ABCA3_uc010bsk.... Hybrid_Cap... view
ABCC4 p.A1288T 13 95686867 95686867 MFE280_ENDOMETR... 37 Missense_Mutation SNP C T uc001vmd.3 ABCC4_uc010afj.... Hybrid_Cap... view
ACSL6 5 131289859 131289859 MFE280_ENDOMETR... 37 3'UTR SNP A C uc003kvx.1 ACSL6_uc003kvv.... Hybrid_Cap... view
ACVRL1 12 52314716 52314716 MFE280_ENDOMETR... 37 3'UTR Del G - uc001rzj.2 ACVRL1_uc001rzk... Hybrid_Cap...
ADAM28 8 24211994 24211997 MFE280_ENDOMETR... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AKAP12 p.1531_1532insE 6 151674116 151674117 MFE280_ENDOMETR... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK1 4 113347609 113347610 MFE280_ENDOMETR... 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.1388_1389FF>F 18 56203253 56203255 MFE280_ENDOMETR... 37 In_Frame_Del Del AAG - uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ARFGEF1 p.D1655G 8 68115482 68115482 MFE280_ENDOMETR... 37 Missense_Mutation SNP T C uc003xxo.1 ARFGEF1_uc003xx... Hybrid_Cap... view
BCR 22 23631813 23631814 MFE280_ENDOMETR... 37 Intron Ins - C rs66503844 uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BTG1 12 92537706 92537707 MFE280_ENDOMETR... 37 3'UTR Ins - T rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
CACNA1F p.815_815E>EE X 49076224 49076225 MFE280_ENDOMETR... 37 In_Frame_Ins Ins - TCC uc004dnb.2 CACNA1F_uc010ni... Hybrid_Cap...
CDK11B 1 1654066 1654068 MFE280_ENDOMETR... 37 Intron Del GCG - uc001agv.1 CDK11B_uc001aha... Hybrid_Cap...
CDK18 1 205495890 205495891 MFE280_ENDOMETR... 37 Intron Del CT - uc001hcr.2 CDK18_uc010pri.... Hybrid_Cap...
CHIC2 4 54876132 54876132 MFE280_ENDOMETR... 37 3'UTR Del C - rs4437313 uc003haj.1 PDGFRA_uc003haa... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 MFE280_ENDOMETR... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
DACH1 13 72014625 72014626 MFE280_ENDOMETR... 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DFNA5 7 24783982 24783982 MFE280_ENDOMETR... 37 Intron Del C - uc010kus.1 DFNA5_uc003swz.... Hybrid_Cap...
DST 6 56484390 56484390 MFE280_ENDOMETR... 37 Intron SNP C A uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
DYRK1A 21 38884966 38884967 MFE280_ENDOMETR... 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EPHA6 3 97367230 97367231 MFE280_ENDOMETR... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ETV1 7 14028708 14028708 MFE280_ENDOMETR... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 MFE280_ENDOMETR... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR2 p.S252W 10 123279677 123279677 MFE280_ENDOMETR... 37 Missense_Mutation SNP G C rs79184941 uc010qtj.1 FGFR2_uc010qtg.... Hybrid_Cap... view
FLT4 5 180035183 180035185 MFE280_ENDOMETR... 37 Intron Del AGT - uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap...
GPC3 X 132888208 132888208 MFE280_ENDOMETR... 37 Intron Del A - uc010nrn.1 GPC3_uc004exd.1... Hybrid_Cap...
GRIA3 X 122318386 122318387 MFE280_ENDOMETR... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 MFE280_ENDOMETR... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HSP90B1 p.E791del 12 104341188 104341190 MFE280_ENDOMETR... 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 MFE280_ENDOMETR... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITGB1 10 33197131 33197134 MFE280_ENDOMETR... 37 Intron Del CTTT - rs116966876 uc001iwq.3 ITGB1_uc001iwp.... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 MFE280_ENDOMETR... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
LIFR p.Y697C 5 38490369 38490369 MFE280_ENDOMETR... 37 Missense_Mutation SNP T C uc010ive.1 LIFR_uc003jli.2... Hybrid_Cap... view
LMNA p.G400G 1 156106047 156106047 MFE280_ENDOMETR... 37 Silent SNP C T uc001fni.2 LMNA_uc001fnf.1... Hybrid_Cap... view
MAF 16 79628537 79628537 MFE280_ENDOMETR... 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 MFE280_ENDOMETR... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 MFE280_ENDOMETR... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 MFE280_ENDOMETR... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPKAPK3 3 50685575 50685575 MFE280_ENDOMETR... 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MLLT10 p.R704L 10 22016857 22016857 MFE280_ENDOMETR... 37 Missense_Mutation SNP G T uc001iqs.2 MLLT10_uc001iqt... Hybrid_Cap... view
MYT1 p.I146I 20 62838987 62838987 MFE280_ENDOMETR... 37 Silent SNP C T uc002yii.2 MYT1_uc002yih.2... Hybrid_Cap... view
NCAM1 11 112832307 112832308 MFE280_ENDOMETR... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 MFE280_ENDOMETR... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NFIA 1 61921185 61921186 MFE280_ENDOMETR... 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NPM1 5 170837734 170837734 MFE280_ENDOMETR... 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 MFE280_ENDOMETR... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 MFE280_ENDOMETR... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
OBSCN p.D2585H 1 228467969 228467969 MFE280_ENDOMETR... 37 Missense_Mutation SNP G C uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
PAX3 2 223158653 223158653 MFE280_ENDOMETR... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PCM1 8 17813218 17813218 MFE280_ENDOMETR... 37 Intron Del T - uc003wyi.3 PCM1_uc011kyh.1... Hybrid_Cap...
PDGFRA 4 55130162 55130162 MFE280_ENDOMETR... 37 Intron Del T - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PDK4 7 95221928 95221928 MFE280_ENDOMETR... 37 Intron Del A - uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap...
PGR 11 100933598 100933599 MFE280_ENDOMETR... 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 MFE280_ENDOMETR... 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3CA p.H1047Y 3 178952084 178952084 MFE280_ENDOMETR... 37 Missense_Mutation SNP C T uc003fjk.2 Hybrid_Cap... view
PIP5K1A p.S465F 1 151214629 151214629 MFE280_ENDOMETR... 37 Missense_Mutation SNP C T uc001exj.2 PIP5K1A_uc001ex... Hybrid_Cap... view
PRKCI 3 170021195 170021196 MFE280_ENDOMETR... 37 3'UTR Ins - A uc003fgs.2 PRKCI_uc003fgt.... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 MFE280_ENDOMETR... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTCH2 p.H622N 1 45293709 45293709 MFE280_ENDOMETR... 37 Missense_Mutation SNP G T rs11573586 uc010olf.1 PTCH2_uc010olg.... Hybrid_Cap... view
PTPRD 9 8733869 8733869 MFE280_ENDOMETR... 37 5'UTR SNP G T uc003zkk.2 PTPRD_uc003zkp.... Hybrid_Cap... view
RPS6KA5 14 91360733 91360734 MFE280_ENDOMETR... 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
RPS6KL1 14 75373626 75373627 MFE280_ENDOMETR... 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SERPINB1 p.A124V 6 2838169 2838169 MFE280_ENDOMETR... 37 Missense_Mutation SNP G A uc003mub.2 SERPINB1_uc003m... Hybrid_Cap... view
SRMS p.P42S 20 62178693 62178693 MFE280_ENDOMETR... 37 Missense_Mutation SNP G A uc002yfi.1 Hybrid_Cap... view
STK31 7 23872024 23872025 MFE280_ENDOMETR... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
STK36 2 219537477 219537477 MFE280_ENDOMETR... 37 5'UTR SNP T G uc002viu.2 STK36_uc002viv.... Hybrid_Cap... view
STRADA 17 61780877 61780877 MFE280_ENDOMETR... 37 3'UTR SNP C T uc002jbm.2 LIMD2_uc002jbl.... Hybrid_Cap... view
TEC 4 48139307 48139310 MFE280_ENDOMETR... 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TLK1 2 171850178 171850179 MFE280_ENDOMETR... 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TMEM123 11 102269398 102269398 MFE280_ENDOMETR... 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TP53 p.A307_splice 17 7577018 7577018 MFE280_ENDOMETR... 37 Splice_Site_SNP SNP C G uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP73 p.P24L 1 3599629 3599629 MFE280_ENDOMETR... 37 Missense_Mutation SNP C T uc001akp.2 TP73_uc001akq.2... Hybrid_Cap... view
TRIM33 1 114940215 114940216 MFE280_ENDOMETR... 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TTN 2 179611427 179611427 MFE280_ENDOMETR... 37 Intron SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 MFE280_ENDOMETR... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
ZBTB16 p.M137V 11 113934431 113934431 MFE280_ENDOMETR... 37 Missense_Mutation SNP A G uc001pop.2 ZBTB16_uc001poo... Hybrid_Cap... view