Annotation Summary for Cell Line: MG-63  

Cell line primary name: MG-63
Cell line aliases:
Gender: M
Site Primary: bone
Histology: osteosarcoma
Hist Subtype1: NS
Notes:
Source: ATCC
Expression arrays: MAKER_p_NCLE_RNA7_HG-U133_Plus_2_D05_454642
SNP arrays: LOBBY_p_NCLE_DNAAffy6_GenomeWideSNP_6_E02_437246
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in MG-63

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 MG63_BONE 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACACA 17 35766564 35766564 MG63_BONE 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ACACB p.E2424K 12 109704060 109704060 MG63_BONE 37 Missense_Mutation SNP G A uc001tob.2 ACACB_uc001toc.... Hybrid_Cap... view
ADAM17 2 9630245 9630245 MG63_BONE 37 3'UTR Del T - uc002qzu.2 IAH1_uc010yiz.1... Hybrid_Cap...
ADAM18 p.C423W 8 39521352 39521352 MG63_BONE 37 Missense_Mutation SNP T G uc003xni.2 ADAM18_uc010lww... Hybrid_Cap... view
ADAM28 8 24211994 24211997 MG63_BONE 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAM29 p.L691del 4 175898744 175898746 MG63_BONE 37 In_Frame_Del Del TTA - uc003iuc.2 ADAM29_uc003iud... Hybrid_Cap...
AGAP2 p.P819H 12 58123523 58123523 MG63_BONE 37 Missense_Mutation SNP G T uc001spq.2 AGAP2_uc001spp.... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 MG63_BONE 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 MG63_BONE 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ARAF X 47430911 47430911 MG63_BONE 37 3'UTR SNP G A uc011mlq.1 Hybrid_Cap... view
ASPH p.A264_splice 8 62550924 62550925 MG63_BONE 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
BCR 22 23632777 23632778 MG63_BONE 37 Intron Ins - T uc002zww.2 BCR_uc002zwx.2_... Hybrid_Cap...
BIRC5 17 76219784 76219785 MG63_BONE 37 3'UTR Ins - AA uc002jvf.2 BIRC5_uc002jvg.... Hybrid_Cap...
CABC1 1 227171585 227171585 MG63_BONE 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CABC1 1 227171736 227171737 MG63_BONE 37 Intron Ins - T rs1574184 uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CAMK2A 5 149602223 149602224 MG63_BONE 37 3'UTR Del AC - uc003lrt.2 CAMK2A_uc003lrs... Hybrid_Cap...
CDK18 p.T234T 1 205495535 205495535 MG63_BONE 37 Silent SNP C T uc001hcr.2 CDK18_uc010pri.... Hybrid_Cap... view
CDK20 9 90582329 90582329 MG63_BONE 37 3'UTR SNP G A uc004apr.2 CDK20_uc004aps.... Hybrid_Cap... view
CEP110 p.I1554T 9 123920284 123920284 MG63_BONE 37 Missense_Mutation SNP T C uc004bkx.1 CEP110_uc010mvo... Hybrid_Cap... view
CHIC2 4 54876132 54876132 MG63_BONE 37 3'UTR Del C - rs4437313 uc003haj.1 PDGFRA_uc003haa... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 MG63_BONE 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CSMD3 p.A1134G 8 113651050 113651050 MG63_BONE 37 Missense_Mutation SNP G C uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CSPP1 p.I1140_splice 8 68102995 68102995 MG63_BONE 37 Splice_Site_SNP SNP G C uc003xxi.2 ARFGEF1_uc003xx... Hybrid_Cap... view
CYLD 16 50830558 50830558 MG63_BONE 37 3'UTR SNP G A uc002egp.1 CYLD_uc002egq.1... Hybrid_Cap... view
DFNA5 p.R238* 7 24749993 24749993 MG63_BONE 37 Nonsense_Mutation SNP G A uc010kus.1 DFNA5_uc003swz.... Hybrid_Cap... view
DNAH8 6 38952247 38952250 MG63_BONE 37 Intron Del CACA - uc003ooe.1 DNAH8_uc003oog.... Hybrid_Cap...
EDN1 6 12290729 12290729 MG63_BONE 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EPHA6 3 97367230 97367231 MG63_BONE 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPS15 1 51822219 51822220 MG63_BONE 37 3'UTR Ins - A rs111272942 uc001csq.1 EPS15_uc009vyz.... Hybrid_Cap...
FGFR1OP 6 167453519 167453520 MG63_BONE 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 MG63_BONE 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 MG63_BONE 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 MG63_BONE 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GLI3 p.S1473R 7 42004252 42004252 MG63_BONE 37 Missense_Mutation SNP G C uc011kbh.1 GLI3_uc011kbg.1... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 MG63_BONE 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 MG63_BONE 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 MG63_BONE 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HDAC1 1 32793286 32793286 MG63_BONE 37 Intron SNP C T uc001bvb.1 HDAC1_uc010ohd.... Hybrid_Cap... view
HERC2 p.R2821C 15 28436381 28436381 MG63_BONE 37 Missense_Mutation SNP G A uc001zbj.2 HERC2_uc001zbk.... Hybrid_Cap... view
HNF1A 12 121434630 121434631 MG63_BONE 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
ILK 11 6630029 6630029 MG63_BONE 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INSRR p.R289C 1 156821756 156821756 MG63_BONE 37 Missense_Mutation SNP G A uc010pht.1 NTRK1_uc001fqf.... Hybrid_Cap... view
ISG15 1 948846 948847 MG63_BONE 37 5'UTR Ins - A rs33916361 uc001acj.3 Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 MG63_BONE 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KLK7 19 51480672 51480675 MG63_BONE 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LRRK1 p.I1945T 15 101606910 101606910 MG63_BONE 37 Missense_Mutation SNP T C uc002bwr.2 LRRK1_uc010usb.... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 MG63_BONE 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 MG63_BONE 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 MG63_BONE 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAPK14 6 36076345 36076354 MG63_BONE 37 3'UTR Del GTGTG... - rs80147786 uc003olp.2 MAPK14_uc003olq... Hybrid_Cap...
MAPKAPK3 3 50685575 50685575 MG63_BONE 37 3'UTR Del A - rs76026164 uc003day.1 MAPKAPK3_uc003d... Hybrid_Cap...
MARK3 p.I345V 14 103933451 103933451 MG63_BONE 37 Missense_Mutation SNP A G uc001ymz.3 MARK3_uc001ymx.... Hybrid_Cap... view
MAST2 p.S121T 1 46295147 46295147 MG63_BONE 37 Missense_Mutation SNP G C uc001cov.2 MAST2_uc001cow.... Hybrid_Cap... view
MAST3 p.R150L 19 18234163 18234163 MG63_BONE 37 Missense_Mutation SNP G T uc002nhz.3 Hybrid_Cap... view
MLLT6 17 36881873 36881873 MG63_BONE 37 3'UTR Del C - uc002hqi.3 MLLT6_uc002hqk.... Hybrid_Cap...
MYST4 p.E1104del 10 76781906 76781908 MG63_BONE 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NCAM1 11 112832307 112832308 MG63_BONE 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 MG63_BONE 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279837 46279839 MG63_BONE 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NCOA3 20 46282339 46282340 MG63_BONE 37 3'UTR Ins - AT uc002xtk.2 NCOA3_uc002xtl.... Hybrid_Cap...
NEK3 p.K313_splice 13 52718050 52718051 MG63_BONE 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NPM1 5 170837734 170837734 MG63_BONE 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 MG63_BONE 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
OBSCN p.S970F 1 228412415 228412415 MG63_BONE 37 Missense_Mutation SNP C T uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
PAX3 2 223158653 223158653 MG63_BONE 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 MG63_BONE 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PLCG2 p.H1072Q 16 81972423 81972423 MG63_BONE 37 Missense_Mutation SNP T G uc002fgt.2 Hybrid_Cap... view
PLCG2 16 81954996 81954997 MG63_BONE 37 Intron Ins - T uc002fgt.2 PLCG2_uc010chg.... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 MG63_BONE 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTPRT p.L830P 20 40827939 40827939 MG63_BONE 37 Missense_Mutation SNP A G uc010ggj.2 PTPRT_uc002xkg.... Hybrid_Cap... view
RGL4 p.E469E 22 24041055 24041055 MG63_BONE 37 Silent SNP G A uc002zxn.2 LOC91316_uc002z... Hybrid_Cap... view
RHPN2 p.R405C 19 33490504 33490504 MG63_BONE 37 Missense_Mutation SNP G A uc002nuf.2 RHPN2_uc010xro.... Hybrid_Cap... view
RPS6 9 19379656 19379656 MG63_BONE 37 Intron SNP T C uc003znv.1 RPS6_uc003znu.1... Hybrid_Cap... view
RPTOR p.R899Q 17 78897361 78897361 MG63_BONE 37 Missense_Mutation SNP G A uc002jyt.1 RPTOR_uc010wug.... Hybrid_Cap... view
SMAD7 18 46447623 46447624 MG63_BONE 37 3'UTR Ins - A uc002ldg.2 SMAD7_uc002ldf.... Hybrid_Cap...
SORL1 p.R904W 11 121429346 121429346 MG63_BONE 37 Missense_Mutation SNP C T uc001pxx.2 Hybrid_Cap... view
TAF15 p.G507D 17 34171823 34171823 MG63_BONE 37 Missense_Mutation SNP G A uc002hkd.2 TAF15_uc002hkc.... Hybrid_Cap... view
TOPBP1 p.N316S 3 133371449 133371449 MG63_BONE 37 Missense_Mutation SNP T C uc003eps.2 Hybrid_Cap... view
TRIM33 1 114940211 114940212 MG63_BONE 37 3'UTR Ins - T rs66490349 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TTBK1 p.E771del 6 43250726 43250728 MG63_BONE 37 In_Frame_Del Del GAA - uc003ouq.1 Hybrid_Cap...
TTN p.K15606N 2 179468892 179468892 MG63_BONE 37 Missense_Mutation SNP T G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 MG63_BONE 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
VPS13B 8 100887922 100887923 MG63_BONE 37 3'UTR Del TG - uc003yiv.2 VPS13B_uc003yiw... Hybrid_Cap...
WNK4 p.P169P 17 40933223 40933223 MG63_BONE 37 Silent SNP C A rs61754328 uc002ibj.2 WNK4_uc010wgx.1... Hybrid_Cap... view