Annotation Summary for Cell Line: MKN1  

Cell line primary name: MKN1
Cell line aliases:
Gender: M
Site Primary: stomach
Histology: carcinoma
Hist Subtype1: mixed_adenosquamous_carcinoma
Notes:
Source: HSRRB
Expression arrays: BUNDS_p_NCLE_RNA5_HG-U133_Plus_2_C02_419716
SNP arrays: PODIA_p_NCLE_DNAAffy7_GenomeWideSNP_6_B12_437554
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in MKN1

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 MKN1_STOMACH 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ABL2 1 179086419 179086420 MKN1_STOMACH 37 Intron Ins - A rs72207641 uc001gmj.3 ABL2_uc010pnf.1... Hybrid_Cap...
ADAM28 8 24211994 24211997 MKN1_STOMACH 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS20 p.D1497N 12 43777744 43777744 MKN1_STOMACH 37 Missense_Mutation SNP C T uc010skx.1 Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 MKN1_STOMACH 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 MKN1_STOMACH 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
ALPK1 4 113347609 113347610 MKN1_STOMACH 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 MKN1_STOMACH 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ATP8B1 p.R384H 18 55359108 55359108 MKN1_STOMACH 37 Missense_Mutation SNP C T rs2271260 uc002lgw.2 Hybrid_Cap... view
AURKC 19 57742494 57742507 MKN1_STOMACH 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BIRC6 p.S1545T 2 32678891 32678891 MKN1_STOMACH 37 Missense_Mutation SNP G C uc010ezu.2 Hybrid_Cap... view
BIRC6 p.T2365M 2 32703728 32703728 MKN1_STOMACH 37 Missense_Mutation SNP C T uc010ezu.2 Hybrid_Cap... view
BRIP1 p.L700_splice 17 59821954 59821954 MKN1_STOMACH 37 Splice_Site_SNP SNP T A uc002izk.1 BRIP1_uc002izl.... Hybrid_Cap... view
BRIP1 p.I633L 17 59857660 59857660 MKN1_STOMACH 37 Missense_Mutation SNP T G uc002izk.1 BRIP1_uc002izl.... Hybrid_Cap... view
CACNB2 10 18828721 18828722 MKN1_STOMACH 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CARD10 p.KE272del 22 37906309 37906314 MKN1_STOMACH 37 In_Frame_Del Del CTCCT... - uc003asx.1 CARD10_uc003ast... Hybrid_Cap...
CDH2 p.A418T 18 25572711 25572711 MKN1_STOMACH 37 Missense_Mutation SNP C T uc002kwg.2 CDH2_uc010xbn.1... Hybrid_Cap... view
CEP110 p.E1762K 9 123924410 123924410 MKN1_STOMACH 37 Missense_Mutation SNP G A uc004bkx.1 CEP110_uc004blb... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 MKN1_STOMACH 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 p.V166I 3 1337326 1337326 MKN1_STOMACH 37 Missense_Mutation SNP G A uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap... view
CNTN6 p.T720M 3 1418752 1418752 MKN1_STOMACH 37 Missense_Mutation SNP C T uc003boz.2 CNTN6_uc011asj.... Hybrid_Cap... view
CREB3L2 p.T100del 7 137612914 137612916 MKN1_STOMACH 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CXCL12 10 44873992 44873993 MKN1_STOMACH 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
DST p.I826V 6 56504771 56504771 MKN1_STOMACH 37 Missense_Mutation SNP T C uc003pdf.2 DST_uc003pcz.3_... Hybrid_Cap... view
EPHA6 3 97367230 97367231 MKN1_STOMACH 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ETV1 7 14028708 14028708 MKN1_STOMACH 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
F12 p.E244A 5 176831569 176831569 MKN1_STOMACH 37 Missense_Mutation SNP T G uc003mgo.3 F12_uc011dfy.1_... Hybrid_Cap... view
FBXW7 p.R465C 4 153249385 153249385 MKN1_STOMACH 37 Missense_Mutation SNP G A uc003ims.2 FBXW7_uc011cii.... Hybrid_Cap... view
FCRL4 p.R97C 1 157559012 157559012 MKN1_STOMACH 37 Missense_Mutation SNP G A uc001fqw.2 FCRL4_uc010phy.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 MKN1_STOMACH 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 MKN1_STOMACH 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FN1 2 216244182 216244185 MKN1_STOMACH 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 MKN1_STOMACH 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 MKN1_STOMACH 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRK7 p.V398F 3 141526628 141526628 MKN1_STOMACH 37 Missense_Mutation SNP G T uc011bnd.1 Hybrid_Cap... view
HNF1A 12 121434630 121434631 MKN1_STOMACH 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HOXC11 12 54369257 54369258 MKN1_STOMACH 37 3'UTR Ins - T uc001sem.2 Hybrid_Cap...
HSP90AB1 p.E555D 6 44219938 44219938 MKN1_STOMACH 37 Missense_Mutation SNP G C uc003oxa.1 HSP90AB1_uc011d... Hybrid_Cap... view
ILK 11 6630029 6630029 MKN1_STOMACH 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 MKN1_STOMACH 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KALRN p.P2265S 3 124390599 124390599 MKN1_STOMACH 37 Missense_Mutation SNP C T uc003ehg.2 KALRN_uc003ehi.... Hybrid_Cap... view
LATS2 13 21620222 21620223 MKN1_STOMACH 37 5'UTR Ins - A rs61240127;rs115723063 uc009zzs.2 LATS2_uc001unr.... Hybrid_Cap...
LRP1B p.R816L 2 141762960 141762960 MKN1_STOMACH 37 Missense_Mutation SNP C A uc002tvj.1 LRP1B_uc010fnl.... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 MKN1_STOMACH 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 MKN1_STOMACH 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 MKN1_STOMACH 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K14 p.P729R 17 43344913 43344913 MKN1_STOMACH 37 Missense_Mutation SNP G C uc002iiw.1 LOC100133991_uc... Hybrid_Cap... view
MCL1 1 150549737 150549744 MKN1_STOMACH 37 3'UTR Del GCTAG... - rs116997851 uc001euz.2 MCL1_uc010pch.1... Hybrid_Cap...
MYO3A p.R658G 10 26414395 26414395 MKN1_STOMACH 37 Missense_Mutation SNP A G rs34675245 uc001isn.2 MYO3A_uc009xko.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 MKN1_STOMACH 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 MKN1_STOMACH 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NEK9 p.567_575NQCMSGIIN>N 14 75570552 75570575 MKN1_STOMACH 37 In_Frame_Del Del TTGAT... - uc001xrl.2 NEK9_uc001xrk.2... Hybrid_Cap...
NPM1 5 170837734 170837734 MKN1_STOMACH 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 MKN1_STOMACH 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 MKN1_STOMACH 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NRBP1 p.H460R 2 27664043 27664043 MKN1_STOMACH 37 Missense_Mutation SNP A G rs34260196 uc002rko.2 NRBP1_uc002rkq.... Hybrid_Cap... view
PAK2 p.E467Q 3 196554115 196554115 MKN1_STOMACH 37 Missense_Mutation SNP G C uc003fwy.3 Hybrid_Cap... view
PAX5 p.A322D 9 36882048 36882048 MKN1_STOMACH 37 Missense_Mutation SNP G T uc003zzo.1 PAX5_uc011lpt.1... Hybrid_Cap... view
PDE4DIP p.E243fs 1 144923729 144923729 MKN1_STOMACH 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDZRN4 p.L88I 12 41900273 41900273 MKN1_STOMACH 37 Missense_Mutation SNP C A uc010skn.1 PDZRN4_uc001rmq... Hybrid_Cap... view
PGR 11 100933598 100933599 MKN1_STOMACH 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PI4K2B 4 25278811 25278811 MKN1_STOMACH 37 3'UTR SNP A C uc003grk.2 PI4K2B_uc011bxs... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 MKN1_STOMACH 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3CA p.E545K 3 178936091 178936091 MKN1_STOMACH 37 Missense_Mutation SNP G A rs104886003 uc003fjk.2 Hybrid_Cap... view
PKN2 p.R878G 1 89298496 89298496 MKN1_STOMACH 37 Missense_Mutation SNP A G uc001dmn.2 PKN2_uc010osp.1... Hybrid_Cap... view
PPP1R3A p.P741Q 7 113518925 113518925 MKN1_STOMACH 37 Missense_Mutation SNP G T uc010ljy.1 Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 MKN1_STOMACH 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PSMA4 15 78834600 78834600 MKN1_STOMACH 37 Intron SNP A T uc002bdu.3 PSMA4_uc010blf.... Hybrid_Cap... view
RAG1 p.Q466* 11 36596250 36596250 MKN1_STOMACH 37 Nonsense_Mutation SNP C T uc001mwu.3 RAG1_uc001mwt.2... Hybrid_Cap... view
RBM15 p.E187D 1 110882588 110882588 MKN1_STOMACH 37 Missense_Mutation SNP G C uc001dzl.1 RBM15_uc001dzm.... Hybrid_Cap... view
RBPJ 4 26431822 26431822 MKN1_STOMACH 37 Intron Del A - rs76214390 uc003grx.1 RBPJ_uc003gry.1... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 MKN1_STOMACH 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RPGRIP1 p.S601L 14 21792816 21792816 MKN1_STOMACH 37 Missense_Mutation SNP C T rs3748360 uc001wag.2 RPGRIP1_uc001wa... Hybrid_Cap... view
RPS6KA5 14 91360733 91360734 MKN1_STOMACH 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
SMG1 p.A3244P 16 18839364 18839364 MKN1_STOMACH 37 Missense_Mutation SNP C G uc002dfm.2 SMG1_uc010bwb.2... Hybrid_Cap... view
STK31 7 23872024 23872025 MKN1_STOMACH 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TEC 4 48139307 48139310 MKN1_STOMACH 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TIE1 1 43772711 43772711 MKN1_STOMACH 37 Intron SNP G C uc001ciu.2 TIE1_uc010okd.1... Hybrid_Cap... view
TMEM123 11 102269398 102269398 MKN1_STOMACH 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNRC6B 22 40574007 40574008 MKN1_STOMACH 37 5'UTR Del TC - uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TNRC6B p.I1368V 22 40697319 40697319 MKN1_STOMACH 37 Missense_Mutation SNP A G uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap... view
TP53 p.V143A 17 7578502 7578502 MKN1_STOMACH 37 Missense_Mutation SNP A G uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP63 3 189507518 189507519 MKN1_STOMACH 37 Intron Ins - AGAG rs62702062;rs79714037 uc003fry.2 TP63_uc003frx.2... Hybrid_Cap...
TRIB3 p.P142R 20 371983 371983 MKN1_STOMACH 37 Missense_Mutation SNP C G rs70961720 uc002wdn.2 TRIB3_uc002wdm.... Hybrid_Cap... view
TRIM24 p.S159* 7 138189146 138189146 MKN1_STOMACH 37 Nonsense_Mutation SNP C G uc003vuc.2 TRIM24_uc003vub... Hybrid_Cap... view
TRPS1 8 116635872 116635873 MKN1_STOMACH 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN 2 179391639 179391640 MKN1_STOMACH 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.E8973K 2 179565880 179565880 MKN1_STOMACH 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.F8778L 2 179569033 179569033 MKN1_STOMACH 37 Missense_Mutation SNP A G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.D8672V 2 179569452 179569452 MKN1_STOMACH 37 Missense_Mutation SNP T A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.L5418P 2 179592320 179592320 MKN1_STOMACH 37 Missense_Mutation SNP A G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 MKN1_STOMACH 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...