Annotation Summary for Cell Line: MKN7  

Cell line primary name: MKN7
Cell line aliases:
Gender: M
Site Primary: stomach
Histology: carcinoma
Hist Subtype1: tubular_adenocarcinoma
Notes:
Source: RIKEN
Expression arrays: SILOS_p_NCLE_RNA9_HG-U133_Plus_2_A08_523516
SNP arrays: FIEFS_p_NCLE_DNA_Affy5_GenomeWideSNP_6_F07_410980
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in MKN7

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
ABCA3 p.F664L 16 2347829 2347829 MKN7_STOMACH 37 Missense_Mutation SNP A G uc002cpy.1 ABCA3_uc010bsk.... Hybrid_Cap... view
ABI1 p.A390T 10 27040710 27040710 MKN7_STOMACH 37 Missense_Mutation SNP C T uc001isx.2 ABI1_uc001ite.2... Hybrid_Cap... view
ADAM28 8 24211994 24211997 MKN7_STOMACH 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
AGAP2 p.A10T 12 58135827 58135827 MKN7_STOMACH 37 Missense_Mutation SNP C T uc001spr.2 TSPAN31_uc001sp... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 MKN7_STOMACH 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 MKN7_STOMACH 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
AKAP9 p.R3712Q 7 91731945 91731945 MKN7_STOMACH 37 Missense_Mutation SNP G A uc003ulg.2 AKAP9_uc003ulf.... Hybrid_Cap... view
AKT3 1 243668379 243668379 MKN7_STOMACH 37 3'UTR SNP C T uc001iab.1 AKT3_uc001hzz.1... Hybrid_Cap... view
AR p.A52T X 66765142 66765142 MKN7_STOMACH 37 Missense_Mutation SNP G A uc004dwu.1 AR_uc011mpd.1_M... Hybrid_Cap... view
ARHGEF10 8 1824649 1824649 MKN7_STOMACH 37 Intron SNP A G uc003wpr.2 ARHGEF10_uc003w... Hybrid_Cap... view
AURKC 19 57742494 57742507 MKN7_STOMACH 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BCL9 1 147083420 147083420 MKN7_STOMACH 37 De_novo_Start_OutOfFrame SNP C T uc001epq.2 BCL9_uc010ozr.1... Hybrid_Cap... view
BIRC2 p.K19fs 11 102220640 102220640 MKN7_STOMACH 37 Frame_Shift_Del Del A - uc001pgy.2 BIRC2_uc010ruq.... Hybrid_Cap...
BIRC6 p.L2833H 2 32724643 32724643 MKN7_STOMACH 37 Missense_Mutation SNP T A uc010ezu.2 Hybrid_Cap... view
BMPR1A 10 88635671 88635671 MKN7_STOMACH 37 5'UTR SNP G A uc001kdy.2 Hybrid_Cap... view
BRCA1 p.V939L 17 41244733 41244733 MKN7_STOMACH 37 Missense_Mutation SNP C G uc002ict.2 BRCA1_uc010whp.... Hybrid_Cap... view
CACNB2 p.S557L 10 18828340 18828340 MKN7_STOMACH 37 Missense_Mutation SNP C T uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap... view
CHD1 5 98192031 98192031 MKN7_STOMACH 37 3'UTR SNP T C uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap... view
CHD1 p.P1684del 5 98192165 98192167 MKN7_STOMACH 37 In_Frame_Del Del AGG - rs79267787;rs61749618 uc003knf.2 CHD1_uc010jbn.2... Hybrid_Cap...
CIT p.V1727F 12 120146016 120146016 MKN7_STOMACH 37 Missense_Mutation SNP C A uc001txj.1 CIT_uc001txh.1_... Hybrid_Cap... view
CLTCL1 p.Y1574fs 22 19171000 19171009 MKN7_STOMACH 37 Frame_Shift_Del Del AGCAG... - uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 MKN7_STOMACH 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 MKN7_STOMACH 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CYP24A1 p.R120H 20 52789538 52789538 MKN7_STOMACH 37 Missense_Mutation SNP C T rs114476330 uc002xwv.2 CYP24A1_uc002xw... Hybrid_Cap... view
DAXX p.E469del 6 33287881 33287883 MKN7_STOMACH 37 In_Frame_Del Del CCT - uc011dre.1 ZBTB22_uc003oeb... Hybrid_Cap...
DCLK2 p.D496N 4 151153849 151153849 MKN7_STOMACH 37 Missense_Mutation SNP G A uc003ilo.3 DCLK2_uc003ilm.... Hybrid_Cap... view
DGKB 7 14216345 14216346 MKN7_STOMACH 37 Intron Ins - AGACT uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap...
DVL1 p.P595P 1 1271750 1271750 MKN7_STOMACH 37 Silent SNP C T uc001aer.3 DVL1_uc002quu.2... Hybrid_Cap... view
DYRK1A 21 38884966 38884967 MKN7_STOMACH 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EDN1 6 12290729 12290729 MKN7_STOMACH 37 5'UTR Del A - uc003nae.3 EDN1_uc010jpb.2... Hybrid_Cap...
EML4 2 42488567 42488567 MKN7_STOMACH 37 Intron SNP G T uc002rsi.2 EML4_uc002rsh.3... Hybrid_Cap... view
EPHA6 3 97367230 97367231 MKN7_STOMACH 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ETV1 7 14028708 14028708 MKN7_STOMACH 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FGFR3 4 1809128 1809129 MKN7_STOMACH 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 MKN7_STOMACH 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FOXP1 p.H53Q 3 71247374 71247374 MKN7_STOMACH 37 Missense_Mutation SNP G T uc003dol.2 FOXP1_uc003dom.... Hybrid_Cap... view
GATS 7 99799059 99799059 MKN7_STOMACH 37 3'UTR SNP A G uc003uua.3 STAG3_uc010lgs.... Hybrid_Cap... view
GPC3 X 132888208 132888208 MKN7_STOMACH 37 Intron Del A - uc010nrn.1 GPC3_uc004exd.1... Hybrid_Cap...
GPR112 p.I2298V X 135438289 135438289 MKN7_STOMACH 37 Missense_Mutation SNP A G uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 MKN7_STOMACH 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 MKN7_STOMACH 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
HECW1 p.Q1213H 7 43546743 43546743 MKN7_STOMACH 37 Missense_Mutation SNP G C uc003tid.1 HECW1_uc011kbi.... Hybrid_Cap... view
HNF1A 12 121434630 121434631 MKN7_STOMACH 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HNF1A p.A544T 12 121437271 121437271 MKN7_STOMACH 37 Missense_Mutation SNP G A uc010szn.1 HNF1A_uc001tzg.... Hybrid_Cap... view
IGF1R 15 99192755 99192763 MKN7_STOMACH 37 5'UTR Del TTTTT... - uc002bul.2 IGF1R_uc010urq.... Hybrid_Cap...
ILK 11 6630029 6630029 MKN7_STOMACH 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 MKN7_STOMACH 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
JAG2 p.V537V 14 105615649 105615649 MKN7_STOMACH 37 Silent SNP G A uc001yqg.2 JAG2_uc010axf.2... Hybrid_Cap... view
KLK7 19 51480672 51480675 MKN7_STOMACH 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LAMA1 p.S1160L 18 7012022 7012022 MKN7_STOMACH 37 Missense_Mutation SNP G A uc002knm.2 LAMA1_uc010wzj.... Hybrid_Cap... view
LRP1 p.V2089M 12 57578700 57578700 MKN7_STOMACH 37 Missense_Mutation SNP G A uc001snd.2 Hybrid_Cap... view
LRRK1 p.I1257V 15 101593206 101593206 MKN7_STOMACH 37 Missense_Mutation SNP A G uc002bwr.2 LRRK1_uc010usb.... Hybrid_Cap... view
MAF 16 79628537 79628537 MKN7_STOMACH 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MALT1 p.E388K 18 56390423 56390423 MKN7_STOMACH 37 Missense_Mutation SNP G A uc002lhm.1 MALT1_uc002lhn.... Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 MKN7_STOMACH 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 MKN7_STOMACH 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAST3 p.L286M 19 18235174 18235174 MKN7_STOMACH 37 Missense_Mutation SNP C A uc002nhz.3 Hybrid_Cap... view
MED13L p.G1817D 12 116413458 116413458 MKN7_STOMACH 37 Missense_Mutation SNP C T uc001tvw.2 Hybrid_Cap... view
MEF2A p.Q430del 15 100252710 100252712 MKN7_STOMACH 37 In_Frame_Del Del CAG - uc010urw.1 MEF2A_uc010urv.... Hybrid_Cap...
MYLK p.E1066del 3 123419117 123419119 MKN7_STOMACH 37 In_Frame_Del Del TTC - rs72491150 uc003ego.2 MYLK_uc011bjw.1... Hybrid_Cap...
MYO3A p.Q283P 10 26315356 26315356 MKN7_STOMACH 37 Missense_Mutation SNP A C uc001isn.2 MYO3A_uc009xko.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 MKN7_STOMACH 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 MKN7_STOMACH 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA1 p.S668F 2 24930342 24930342 MKN7_STOMACH 37 Missense_Mutation SNP C T uc002rfk.2 NCOA1_uc010eye.... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 MKN7_STOMACH 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFIA 1 61921185 61921186 MKN7_STOMACH 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NLRP3 p.G811S 1 247597508 247597508 MKN7_STOMACH 37 Missense_Mutation SNP G A uc001icr.2 NLRP3_uc001ics.... Hybrid_Cap... view
NPAT p.D166D 11 108059891 108059891 MKN7_STOMACH 37 Silent SNP A G uc001pjz.3 NPAT_uc001pka.2... Hybrid_Cap... view
NPM1 5 170837734 170837734 MKN7_STOMACH 37 3'UTR Del T - uc011dex.1 NPM1_uc003mbi.2... Hybrid_Cap...
NPR1 1 153665919 153665920 MKN7_STOMACH 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 MKN7_STOMACH 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP214 p.S2006L 9 134103661 134103661 MKN7_STOMACH 37 Missense_Mutation SNP C T uc004cag.2 NUP214_uc004cah... Hybrid_Cap... view
OBSCN p.G2687G 1 228468361 228468361 MKN7_STOMACH 37 Silent SNP C A uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
PAK7 p.E468K 20 9546620 9546620 MKN7_STOMACH 37 Missense_Mutation SNP C T uc002wnl.2 PAK7_uc002wnk.2... Hybrid_Cap... view
PAX3 2 223066017 223066018 MKN7_STOMACH 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 MKN7_STOMACH 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX5 9 36840427 36840427 MKN7_STOMACH 37 3'UTR Del G - uc003zzo.1 PAX5_uc011lpt.1... Hybrid_Cap...
PDGFRA 4 55130162 55130162 MKN7_STOMACH 37 Intron Del T - uc003han.3 PDGFRA_uc003haa... Hybrid_Cap...
PGR 11 100933598 100933599 MKN7_STOMACH 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIK3C2A 11 17111198 17111199 MKN7_STOMACH 37 3'UTR Del GT - uc001mmq.3 PIK3C2A_uc009yg... Hybrid_Cap...
PIK3R1 5 67586702 67586702 MKN7_STOMACH 37 Intron SNP G T uc003jva.2 PIK3R1_uc003jvb... Hybrid_Cap... view
PKN3 p.Y664C 9 131480609 131480609 MKN7_STOMACH 37 Missense_Mutation SNP A G uc004bvw.2 PKN3_uc010myh.2... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 MKN7_STOMACH 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
RALBP1 p.V625I 18 9535840 9535840 MKN7_STOMACH 37 Missense_Mutation SNP G A uc002kob.2 RALBP1_uc002koc... Hybrid_Cap... view
RARB p.I132T 3 25542740 25542740 MKN7_STOMACH 37 Missense_Mutation SNP T C uc011awl.1 RARB_uc003cdi.1... Hybrid_Cap... view
RASGRF1 p.F266L 15 79339168 79339168 MKN7_STOMACH 37 Missense_Mutation SNP G T uc002beq.2 RASGRF1_uc002be... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 MKN7_STOMACH 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
SACS p.L3453R 13 23907657 23907657 MKN7_STOMACH 37 Missense_Mutation SNP A C uc001uon.2 SACS_uc001uoo.2... Hybrid_Cap... view
SKP2 5 36152261 36152261 MKN7_STOMACH 37 5'UTR SNP C A uc003jkc.1 SKP2_uc011cou.1... Hybrid_Cap... view
SNX19 p.R100W 11 130785537 130785537 MKN7_STOMACH 37 Missense_Mutation SNP G A uc001qgk.3 SNX19_uc010sce.... Hybrid_Cap... view
SS18L1 20 60754484 60754488 MKN7_STOMACH 37 3'UTR Del GTATT - uc002ycb.2 SS18L1_uc002ybz... Hybrid_Cap...
STAT5A 17 40462797 40462800 MKN7_STOMACH 37 3'UTR Del TGTG - uc002hzj.1 STAT5A_uc010cya... Hybrid_Cap...
SULF2 p.L522P 20 46300953 46300953 MKN7_STOMACH 37 Missense_Mutation SNP A G uc002xto.2 SULF2_uc002xtr.... Hybrid_Cap... view
TAB1 p.P465T 22 39824046 39824046 MKN7_STOMACH 37 Missense_Mutation SNP C A uc003axr.2 TAB1_uc003axt.2... Hybrid_Cap... view
TG p.V845F 8 133900585 133900585 MKN7_STOMACH 37 Missense_Mutation SNP G T rs115070736 uc003ytw.2 Hybrid_Cap... view
TLK1 2 171850178 171850179 MKN7_STOMACH 37 3'UTR Ins - AA rs71008739 uc002ugo.2 TLK1_uc002ugn.2... Hybrid_Cap...
TMEM123 11 102269398 102269398 MKN7_STOMACH 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNFRSF13B p.G76S 17 16852271 16852271 MKN7_STOMACH 37 Missense_Mutation SNP C T uc002gqs.1 TNFRSF13B_uc010... Hybrid_Cap... view
TNFRSF1B p.R345Q 1 12262157 12262157 MKN7_STOMACH 37 Missense_Mutation SNP G A uc001att.2 TNFRSF1B_uc001a... Hybrid_Cap... view
TP53 p.P278S 17 7577106 7577106 MKN7_STOMACH 37 Missense_Mutation SNP G A rs17849781 uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRPS1 8 116635872 116635873 MKN7_STOMACH 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TRRAP p.R119C 7 98490140 98490140 MKN7_STOMACH 37 Missense_Mutation SNP C T uc003upp.2 TRRAP_uc011kis.... Hybrid_Cap... view
TTN p.V27855I 2 179416360 179416360 MKN7_STOMACH 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.K10732M 2 179516230 179516230 MKN7_STOMACH 37 Missense_Mutation SNP T A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 MKN7_STOMACH 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
ZAK p.H651R 2 174131027 174131027 MKN7_STOMACH 37 Missense_Mutation SNP A G uc002uhz.2 Hybrid_Cap... view
ZNF608 p.G463V 5 123984689 123984689 MKN7_STOMACH 37 Missense_Mutation SNP C A uc003ktq.1 ZNF608_uc003ktr... Hybrid_Cap... view