Annotation Summary for Cell Line: MOLM-13  

Cell line primary name: MOLM-13
Cell line aliases:
Gender: M
Site Primary: haematopoietic_and_lymphoid_tissue
Histology: haematopoietic_neoplasm
Hist Subtype1: acute_myeloid_leukaemia
Notes:
Source: DSMZ
Expression arrays: PARES_p_NCLE_RNA_Redo_HG-U133_Plus_2_E03_257698
SNP arrays: HONEY_p_NCLE_DNAAffy3_S_GenomeWideSNP_6_F05_293408
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in MOLM-13

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 MOLM13_HAEMATOP... 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACOXL p.A361S 2 111744706 111744706 MOLM13_HAEMATOP... 37 Missense_Mutation SNP G T uc010yxk.1 ACOXL_uc010fkc.... Hybrid_Cap... view
ADAM28 8 24211994 24211997 MOLM13_HAEMATOP... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTSL3 15 84706673 84706676 MOLM13_HAEMATOP... 37 3'UTR Del CAAA - uc002bjz.3 ADAMTSL3_uc010b... Hybrid_Cap...
ADCK2 7 140394736 140394736 MOLM13_HAEMATOP... 37 3'UTR SNP C T uc003vvy.1 ADCK2_uc003vvz.... Hybrid_Cap... view
AFF3 p.T257A 2 100623273 100623273 MOLM13_HAEMATOP... 37 Missense_Mutation SNP T C uc002taf.2 AFF3_uc002tag.2... Hybrid_Cap... view
AIFM1 p.R569R X 129264008 129264008 MOLM13_HAEMATOP... 37 Silent SNP C T rs2239772 uc004evg.2 AIFM1_uc011mur.... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 MOLM13_HAEMATOP... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 MOLM13_HAEMATOP... 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
AKAP9 p.S1848C 7 91682214 91682214 MOLM13_HAEMATOP... 37 Missense_Mutation SNP C G uc003ulg.2 AKAP9_uc003ulf.... Hybrid_Cap... view
ALPK3 15 85411713 85411713 MOLM13_HAEMATOP... 37 3'UTR Del C - uc002ble.2 ALPK3_uc010upc.... Hybrid_Cap...
AURKC 19 57742494 57742507 MOLM13_HAEMATOP... 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BIRC6 p.K1371E 2 32667396 32667396 MOLM13_HAEMATOP... 37 Missense_Mutation SNP A G uc010ezu.2 Hybrid_Cap... view
BRCA2 p.Q819R 13 32910948 32910948 MOLM13_HAEMATOP... 37 Missense_Mutation SNP A G uc001uub.1 Hybrid_Cap... view
CACNB2 10 18828721 18828722 MOLM13_HAEMATOP... 37 3'UTR Ins - AA rs3841459 uc001ipr.2 CACNB2_uc009xjz... Hybrid_Cap...
CBL p.Q409_splice 11 119149006 119149019 MOLM13_HAEMATOP... 37 Splice_Site_Del Del AGGTA... - uc001pwe.2 Hybrid_Cap...
CD40 20 44757839 44757839 MOLM13_HAEMATOP... 37 3'UTR SNP G A uc002xrg.1 CD40_uc002xrh.1... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 MOLM13_HAEMATOP... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 MOLM13_HAEMATOP... 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
DACH1 13 72014625 72014626 MOLM13_HAEMATOP... 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
EGF p.E1134fs 4 110932389 110932390 MOLM13_HAEMATOP... 37 Frame_Shift_Ins Ins - C rs11569144 uc003hzy.3 EGF_uc011cfu.1_... Hybrid_Cap...
EPHA6 3 97367230 97367231 MOLM13_HAEMATOP... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHA7 p.C250Y 6 94120302 94120302 MOLM13_HAEMATOP... 37 Missense_Mutation SNP C T uc003poe.2 EPHA7_uc003pof.... Hybrid_Cap... view
ESR2 14 64701617 64701617 MOLM13_HAEMATOP... 37 Intron SNP A G uc001xha.1 ESR2_uc001xgu.2... Hybrid_Cap... view
ETV1 7 14028708 14028708 MOLM13_HAEMATOP... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FBXO43 p.Y652C 8 101146202 101146202 MOLM13_HAEMATOP... 37 Missense_Mutation SNP T C uc003yjd.2 FBXO43_uc003yje... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 MOLM13_HAEMATOP... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 MOLM13_HAEMATOP... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 MOLM13_HAEMATOP... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 MOLM13_HAEMATOP... 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FN1 2 216244182 216244185 MOLM13_HAEMATOP... 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
FSCB p.P614R 14 44974350 44974350 MOLM13_HAEMATOP... 37 Missense_Mutation SNP G C uc001wvn.2 Hybrid_Cap... view
GRIA3 X 122318386 122318387 MOLM13_HAEMATOP... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIK1 p.F225I 21 31045356 31045356 MOLM13_HAEMATOP... 37 Missense_Mutation SNP A T uc011acs.1 GRIK1_uc002ynn.... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 MOLM13_HAEMATOP... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HDAC2 6 114262077 114262080 MOLM13_HAEMATOP... 37 3'UTR Del AAAC - rs3217728 uc003pwd.1 HDAC2_uc003pwc.... Hybrid_Cap...
HERC2 p.R2126L 15 28459400 28459400 MOLM13_HAEMATOP... 37 Missense_Mutation SNP C A uc001zbj.2 Hybrid_Cap... view
HSP90B1 p.E791del 12 104341188 104341190 MOLM13_HAEMATOP... 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 MOLM13_HAEMATOP... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
INPP5D p.D111N 2 233986949 233986949 MOLM13_HAEMATOP... 37 Missense_Mutation SNP G A uc010zmo.1 INPP5D_uc010zmp... Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 MOLM13_HAEMATOP... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
LATS2 13 21620222 21620223 MOLM13_HAEMATOP... 37 5'UTR Ins - A rs61240127;rs115723063 uc009zzs.2 LATS2_uc001unr.... Hybrid_Cap...
LMTK2 p.S559N 7 97821453 97821453 MOLM13_HAEMATOP... 37 Missense_Mutation SNP G A uc003upd.1 Hybrid_Cap... view
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 MOLM13_HAEMATOP... 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 MOLM13_HAEMATOP... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 MOLM13_HAEMATOP... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 MOLM13_HAEMATOP... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MECOM 3 169381200 169381201 MOLM13_HAEMATOP... 37 5'UTR Ins - T uc011bpj.1 MECOM_uc011bpk.... Hybrid_Cap...
MLL p.A1653T 11 118362596 118362596 MOLM13_HAEMATOP... 37 Missense_Mutation SNP G A uc001ptb.2 MLL_uc001pta.2_... Hybrid_Cap... view
MMP20 p.L407F 11 102464198 102464198 MOLM13_HAEMATOP... 37 Missense_Mutation SNP G A uc001phc.2 Hybrid_Cap... view
MSH2 p.P837T 2 47707885 47707885 MOLM13_HAEMATOP... 37 Missense_Mutation SNP C A uc002rvz.2 MSH2_uc010yoh.1... Hybrid_Cap... view
MSH3 p.63_64insAAP 5 79950724 79950725 MOLM13_HAEMATOP... 37 In_Frame_Ins Ins - CCGCAGCGC rs72432994 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MST1R 3 49941114 49941114 MOLM13_HAEMATOP... 37 5'UTR SNP C A uc003cxy.3 MST1R_uc011bdd.... Hybrid_Cap... view
MTOR p.T571K 1 11300434 11300434 MOLM13_HAEMATOP... 37 Missense_Mutation SNP G T uc001asd.2 Hybrid_Cap... view
MYLK p.E1066del 3 123419117 123419119 MOLM13_HAEMATOP... 37 In_Frame_Del Del TTC - rs72491150 uc003ego.2 MYLK_uc011bjw.1... Hybrid_Cap...
NCAM1 11 112832307 112832308 MOLM13_HAEMATOP... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 MOLM13_HAEMATOP... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.R353L 20 46262885 46262885 MOLM13_HAEMATOP... 37 Missense_Mutation SNP G T uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 MOLM13_HAEMATOP... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NEK5 p.Q132R 13 52684631 52684631 MOLM13_HAEMATOP... 37 Missense_Mutation SNP T C uc001vge.2 NEK5_uc001vgf.2... Hybrid_Cap... view
NLRP1 p.V937I 17 5442796 5442796 MOLM13_HAEMATOP... 37 Missense_Mutation SNP C T uc002gci.2 NLRP1_uc002gcg.... Hybrid_Cap... view
NOTCH4 p.A439P 6 32187906 32187906 MOLM13_HAEMATOP... 37 Missense_Mutation SNP C G uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap... view
NOTCH4 p.15_16LL>L 6 32191659 32191661 MOLM13_HAEMATOP... 37 In_Frame_Del Del AGC - uc003obb.2 NOTCH4_uc011dpu... Hybrid_Cap...
NPR1 1 153665919 153665920 MOLM13_HAEMATOP... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 MOLM13_HAEMATOP... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NUP98 11 3697276 3697276 MOLM13_HAEMATOP... 37 3'UTR SNP G A uc001lyh.2 NUP98_uc001lyi.... Hybrid_Cap... view
OBSCN p.R7417T 1 228560729 228560729 MOLM13_HAEMATOP... 37 Missense_Mutation SNP G C rs78693251 uc009xez.1 OBSCN_uc001hsr.... Hybrid_Cap... view
PAX3 2 223066017 223066018 MOLM13_HAEMATOP... 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 MOLM13_HAEMATOP... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP 1 144863620 144863620 MOLM13_HAEMATOP... 37 Intron SNP A G uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PDE4DIP p.L601fs 1 144915624 144915624 MOLM13_HAEMATOP... 37 Frame_Shift_Del Del G - rs1778112 uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.E243fs 1 144923729 144923729 MOLM13_HAEMATOP... 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PIK3C2G p.V264fs 12 18443818 18443827 MOLM13_HAEMATOP... 37 Frame_Shift_Del Del TTAAT... - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PLCG1 p.N1289D 20 39803138 39803138 MOLM13_HAEMATOP... 37 Missense_Mutation SNP A G uc002xjo.1 PLCG1_uc002xjp.... Hybrid_Cap... view
PML p.R689W 15 74336765 74336765 MOLM13_HAEMATOP... 37 Missense_Mutation SNP C T uc002awv.2 PML_uc002awu.2_... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 MOLM13_HAEMATOP... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKG1 p.K141Q 10 52913033 52913033 MOLM13_HAEMATOP... 37 Missense_Mutation SNP A C uc001jjo.2 PRKG1_uc001jjm.... Hybrid_Cap... view
SBDS p.P6A 7 66460389 66460389 MOLM13_HAEMATOP... 37 Missense_Mutation SNP G C uc003tvm.1 TYW1_uc003tvn.2... Hybrid_Cap... view
TEC 4 48139307 48139310 MOLM13_HAEMATOP... 37 3'UTR Del TTAT - rs79098351 uc003gxz.2 Hybrid_Cap...
TGFB2 1 218519928 218519929 MOLM13_HAEMATOP... 37 5'UTR Ins - AAAC uc001hln.2 TGFB2_uc001hll.... Hybrid_Cap...
TGS1 p.P597R 8 56711720 56711720 MOLM13_HAEMATOP... 37 Missense_Mutation SNP C G uc003xsj.3 TGS1_uc010lyh.2... Hybrid_Cap... view
TNFRSF13B p.A149T 17 16852052 16852052 MOLM13_HAEMATOP... 37 Missense_Mutation SNP C T rs72553880 uc002gqs.1 TNFRSF13B_uc010... Hybrid_Cap... view
TRPM6 p.R1088S 9 77390940 77390940 MOLM13_HAEMATOP... 37 Missense_Mutation SNP G T uc004ajl.1 TRPM6_uc004ajk.... Hybrid_Cap... view
TTN 2 179391639 179391640 MOLM13_HAEMATOP... 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.G28220S 2 179413991 179413991 MOLM13_HAEMATOP... 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.S20363N 2 179442361 179442361 MOLM13_HAEMATOP... 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.P9577L 2 179549988 179549988 MOLM13_HAEMATOP... 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
UNC13C 15 54919356 54919356 MOLM13_HAEMATOP... 37 3'UTR SNP C T uc002ack.2 UNC13C_uc002acm... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 MOLM13_HAEMATOP... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WNK2 9 96080121 96080121 MOLM13_HAEMATOP... 37 Intron SNP G A uc004ati.1 WNK2_uc011lud.1... Hybrid_Cap... view
ZNF608 p.P1134L 5 123982676 123982676 MOLM13_HAEMATOP... 37 Missense_Mutation SNP G A uc003ktq.1 ZNF608_uc003ktr... Hybrid_Cap... view