Annotation Summary for Cell Line: MOLM-16  

Cell line primary name: MOLM-16
Cell line aliases:
Gender: F
Site Primary: haematopoietic_and_lymphoid_tissue
Histology: haematopoietic_neoplasm
Hist Subtype1: acute_myeloid_leukaemia
Notes:
Source: DSMZ
Expression arrays: WATCH_p_NCLE_RNA8_HG-U133_Plus_2_H04_474738
SNP arrays: AWASH_p_NCLE_DNAAffy10_GenomeWideSNP_6_F06_542882
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in MOLM-16

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 MOLM16_HAEMATOP... 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM28 8 24211994 24211997 MOLM16_HAEMATOP... 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADAMTS18 p.V341V 16 77397732 77397732 MOLM16_HAEMATOP... 37 Silent SNP A T uc002ffc.3 ADAMTS18_uc010c... Hybrid_Cap... view
AIFM1 p.R569R X 129264008 129264008 MOLM16_HAEMATOP... 37 Silent SNP C T rs2239772 uc004evg.2 AIFM1_uc011mur.... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 MOLM16_HAEMATOP... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
AKAP9 p.1335_1336insQ 7 91652178 91652179 MOLM16_HAEMATOP... 37 In_Frame_Ins Ins - AAC rs34756483 uc003ulg.2 AKAP9_uc003ule.... Hybrid_Cap...
AMHR2 p.R71G 12 53818233 53818233 MOLM16_HAEMATOP... 37 Missense_Mutation SNP C G uc001scx.1 AMHR2_uc009zmy.... Hybrid_Cap... view
ARNT p.P402L 1 150799056 150799056 MOLM16_HAEMATOP... 37 Missense_Mutation SNP G A uc001evr.1 ARNT_uc001evs.1... Hybrid_Cap... view
AURKC 19 57742494 57742507 MOLM16_HAEMATOP... 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
CIT p.G429S 12 120241020 120241020 MOLM16_HAEMATOP... 37 Missense_Mutation SNP C T uc001txj.1 CIT_uc001txh.1_... Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 MOLM16_HAEMATOP... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN6 3 1339681 1339686 MOLM16_HAEMATOP... 37 Intron Del GTTTT... - uc003boz.2 CNTN6_uc010hbo.... Hybrid_Cap...
CREB3L2 p.T100del 7 137612914 137612916 MOLM16_HAEMATOP... 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CREBBP p.2211_2213QQQ>Q 16 3778410 3778415 MOLM16_HAEMATOP... 37 In_Frame_Del Del TGCTG... - uc002cvv.2 CREBBP_uc002cvw... Hybrid_Cap...
DGKB 7 14216345 14216346 MOLM16_HAEMATOP... 37 Intron Ins - AGACT uc003ssz.2 DGKB_uc011jxt.1... Hybrid_Cap...
EDN1 6 12296150 12296151 MOLM16_HAEMATOP... 37 Intron Ins - T rs66570617 uc003nae.3 EDN1_uc003nad.2... Hybrid_Cap...
EGF p.E1134fs 4 110932389 110932390 MOLM16_HAEMATOP... 37 Frame_Shift_Ins Ins - C rs11569144 uc003hzy.3 EGF_uc011cfu.1_... Hybrid_Cap...
EML4 p.I284T 2 42510022 42510022 MOLM16_HAEMATOP... 37 Missense_Mutation SNP T C uc002rsi.2 EML4_uc010fap.2... Hybrid_Cap... view
EPHA6 3 97367230 97367231 MOLM16_HAEMATOP... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
EPHA8 p.E424K 1 22915654 22915654 MOLM16_HAEMATOP... 37 Missense_Mutation SNP G A uc001bfx.1 EPHA8_uc001bfw.... Hybrid_Cap... view
ETV1 p.F81L 7 13978866 13978866 MOLM16_HAEMATOP... 37 Missense_Mutation SNP A G uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap... view
ETV1 7 14028708 14028708 MOLM16_HAEMATOP... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FANCI p.S371G 15 89817534 89817534 MOLM16_HAEMATOP... 37 Missense_Mutation SNP A G uc010bnp.1 FANCI_uc002bnm.... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 MOLM16_HAEMATOP... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 MOLM16_HAEMATOP... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 MOLM16_HAEMATOP... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
GPR112 p.D2657del X 135474445 135474447 MOLM16_HAEMATOP... 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 MOLM16_HAEMATOP... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 MOLM16_HAEMATOP... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
GUCY2F p.Q638* X 108652277 108652277 MOLM16_HAEMATOP... 37 Nonsense_Mutation SNP G A uc004eod.3 GUCY2F_uc011msq... Hybrid_Cap... view
HERC2 p.A330T 15 28517456 28517456 MOLM16_HAEMATOP... 37 Missense_Mutation SNP C T uc001zbj.2 HERC2_uc001zbl.... Hybrid_Cap... view
HNF1A 12 121434630 121434631 MOLM16_HAEMATOP... 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSP90B1 p.E791del 12 104341188 104341190 MOLM16_HAEMATOP... 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 MOLM16_HAEMATOP... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
IRS1 p.882_883insQ 2 227660807 227660808 MOLM16_HAEMATOP... 37 In_Frame_Ins Ins - GCT uc002voh.3 Hybrid_Cap...
ITPR2 p.R470_splice 12 26834804 26834805 MOLM16_HAEMATOP... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KALRN p.P2255T 3 124390569 124390569 MOLM16_HAEMATOP... 37 Missense_Mutation SNP C A uc003ehg.2 KALRN_uc003ehi.... Hybrid_Cap... view
LIMK2 p.V514I 22 31669482 31669482 MOLM16_HAEMATOP... 37 Missense_Mutation SNP G A rs115349954 uc003akj.2 LIMK2_uc003akg.... Hybrid_Cap... view
MAML2 p.604_607QQQQ>Q 11 95825375 95825383 MOLM16_HAEMATOP... 37 In_Frame_Del Del TGCTG... - rs113349418 uc001pfw.1 Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 MOLM16_HAEMATOP... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAPK3 16 30133399 30133399 MOLM16_HAEMATOP... 37 Intron SNP G A uc002dws.2 BOLA2_uc010bzb.... Hybrid_Cap... view
MAPKBP1 15 42104865 42104865 MOLM16_HAEMATOP... 37 Intron SNP G T uc001zok.3 MAPKBP1_uc001zo... Hybrid_Cap... view
MLL p.V1368L 11 118354913 118354913 MOLM16_HAEMATOP... 37 Missense_Mutation SNP G C uc001ptb.2 MLL_uc001pta.2_... Hybrid_Cap... view
MSH3 p.63_64insAAP 5 79950724 79950725 MOLM16_HAEMATOP... 37 In_Frame_Ins Ins - CCGCAGCGC rs72432994 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MYLK p.E1066del 3 123419117 123419119 MOLM16_HAEMATOP... 37 In_Frame_Del Del TTC - rs72491150 uc003ego.2 MYLK_uc011bjw.1... Hybrid_Cap...
MYO3A p.G1424S 10 26463463 26463463 MOLM16_HAEMATOP... 37 Missense_Mutation SNP G A uc001isn.2 MYO3A_uc009xkp.... Hybrid_Cap... view
MYST3 p.S1637C 8 41790829 41790829 MOLM16_HAEMATOP... 37 Missense_Mutation SNP T A uc010lxb.2 MYST3_uc010lxc.... Hybrid_Cap... view
MYST4 p.E1104del 10 76781906 76781908 MOLM16_HAEMATOP... 37 In_Frame_Del Del GAA - rs79644703 uc001jwn.1 MYST4_uc001jwm.... Hybrid_Cap...
NCAM1 11 112832307 112832308 MOLM16_HAEMATOP... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 MOLM16_HAEMATOP... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.Q1276del 20 46279837 46279839 MOLM16_HAEMATOP... 37 In_Frame_Del Del CAG - rs2664555 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NPR1 1 153665919 153665920 MOLM16_HAEMATOP... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 MOLM16_HAEMATOP... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
OBSCN p.V1930M 1 228462377 228462377 MOLM16_HAEMATOP... 37 Missense_Mutation SNP G A uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
OBSCN p.S5344L 1 228521458 228521458 MOLM16_HAEMATOP... 37 Missense_Mutation SNP C T uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
OBSCN p.G6151V 1 228539054 228539054 MOLM16_HAEMATOP... 37 Missense_Mutation SNP G T uc009xez.1 OBSCN_uc001hsn.... Hybrid_Cap... view
OBSCN p.G7500R 1 228562288 228562288 MOLM16_HAEMATOP... 37 Missense_Mutation SNP G A uc009xez.1 OBSCN_uc001hsr.... Hybrid_Cap... view
PARP1 1 226549059 226549059 MOLM16_HAEMATOP... 37 3'UTR SNP G T uc001hqd.3 Hybrid_Cap... view
PAX3 2 223066017 223066018 MOLM16_HAEMATOP... 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDE4DIP 1 144863620 144863620 MOLM16_HAEMATOP... 37 Intron SNP A G uc001elw.3 NBPF10_uc009wir... Hybrid_Cap... view
PDE4DIP p.L601fs 1 144915624 144915624 MOLM16_HAEMATOP... 37 Frame_Shift_Del Del G - rs1778112 uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PDE4DIP p.E243fs 1 144923729 144923729 MOLM16_HAEMATOP... 37 Frame_Shift_Del Del T - uc001elw.3 NBPF10_uc009wir... Hybrid_Cap...
PIK3C2G p.P129del 12 18435399 18435401 MOLM16_HAEMATOP... 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PRKDC p.L1244fs 8 48805816 48805817 MOLM16_HAEMATOP... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTCH2 p.R175L 1 45297648 45297648 MOLM16_HAEMATOP... 37 Missense_Mutation SNP C A uc010olf.1 PTCH2_uc010olg.... Hybrid_Cap... view
PTCH2 p.R74H 1 45307563 45307563 MOLM16_HAEMATOP... 37 Missense_Mutation SNP C T uc010olf.1 PTCH2_uc010olg.... Hybrid_Cap... view
RASGRF1 15 79277150 79277151 MOLM16_HAEMATOP... 37 Intron Ins - C rs67045840;rs77640668 uc002beq.2 RASGRF1_uc002be... Hybrid_Cap...
RECQL4 p.R766fs 8 145738768 145738768 MOLM16_HAEMATOP... 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RIPK2 8 90770187 90770187 MOLM16_HAEMATOP... 37 5'UTR SNP C T uc003yee.2 RIPK2_uc003yef.... Hybrid_Cap... view
ROBO1 p.F472Y 3 78719379 78719379 MOLM16_HAEMATOP... 37 Missense_Mutation SNP A T uc003dqe.2 ROBO1_uc003dqb.... Hybrid_Cap... view
ROBO2 3 77666937 77666937 MOLM16_HAEMATOP... 37 Intron Del A - rs78745603 uc003dpz.2 ROBO2_uc003dpy.... Hybrid_Cap...
RPN1 3 128369705 128369705 MOLM16_HAEMATOP... 37 5'UTR SNP C T uc003ekr.1 RPN1_uc011bkq.1... Hybrid_Cap... view
RPS6KL1 14 75373626 75373627 MOLM16_HAEMATOP... 37 3'UTR Ins - TGAT uc001xqx.1 RPS6KL1_uc001xq... Hybrid_Cap...
SEPT6 X 118759335 118759335 MOLM16_HAEMATOP... 37 3'UTR SNP A G uc004ers.2 SEPT6_uc010nqk.... Hybrid_Cap... view
STK25 2 242435659 242435662 MOLM16_HAEMATOP... 37 Intron Del AAGG - rs3215138;rs75497042 uc002wbm.2 STK25_uc002wbk.... Hybrid_Cap...
TP53 p.C238S 17 7577568 7577568 MOLM16_HAEMATOP... 37 Missense_Mutation SNP C G uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TP53 p.V173M 17 7578413 7578413 MOLM16_HAEMATOP... 37 Missense_Mutation SNP C T uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM33 1 114940211 114940212 MOLM16_HAEMATOP... 37 3'UTR Ins - T rs66490349 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRPS1 8 116635872 116635873 MOLM16_HAEMATOP... 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TTN p.R31903Q 2 179397930 179397930 MOLM16_HAEMATOP... 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.R22789C 2 179434790 179434790 MOLM16_HAEMATOP... 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.I20401F 2 179442157 179442157 MOLM16_HAEMATOP... 37 Missense_Mutation SNP T A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 MOLM16_HAEMATOP... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...