Annotation Summary for Cell Line: MOLP-8  

Cell line primary name: MOLP-8
Cell line aliases:
Gender: M
Site Primary: haematopoietic_and_lymphoid_tissue
Histology: lymphoid_neoplasm
Hist Subtype1: plasma_cell_myeloma
Notes:
Source: DSMZ
Expression arrays: WATCH_p_NCLE_RNA8_HG-U133_Plus_2_H12_474618
SNP arrays: CHARY_p_NCLE_DNAAffy9_GenomeWideSNP_6_F10_490358
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in MOLP-8

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.541_542QQ>Q 2 69741754 69741756 MOLP8_HAEMATOPO... 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ADAM12 p.A327T 10 127787011 127787011 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP C T uc001ljk.2 ADAM12_uc010qul... Hybrid_Cap... view
AKAP12 p.1531_1532insE 6 151674116 151674117 MOLP8_HAEMATOPO... 37 In_Frame_Ins Ins - GAG rs34737819 uc011eep.1 AKAP12_uc003qoe... Hybrid_Cap...
ALPK1 4 113347609 113347610 MOLP8_HAEMATOPO... 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 MOLP8_HAEMATOPO... 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
AURKC 19 57742531 57742532 MOLP8_HAEMATOPO... 37 5'UTR Ins - C uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BMPR1A p.K177_splice 10 88659883 88659884 MOLP8_HAEMATOPO... 37 Splice_Site_DNP DNP AG TT uc001kdy.2 Hybrid_Cap...
BMX p.K59E X 15527488 15527488 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP A G uc004cww.2 BMX_uc004cwx.3_... Hybrid_Cap... view
BRD3 9 136898621 136898621 MOLP8_HAEMATOPO... 37 3'UTR SNP T C uc004cew.2 Hybrid_Cap... view
CDK17 p.M1R 12 96728613 96728613 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP A C uc001tep.1 CDK17_uc009ztk.... Hybrid_Cap... view
CHRNA5 15 78885615 78885616 MOLP8_HAEMATOPO... 37 3'UTR Ins - TA rs72534078 uc002bdy.2 CHRNA3_uc002bea... Hybrid_Cap...
CIC p.G555R 19 42794583 42794583 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP G C uc002otf.1 Hybrid_Cap... view
CIC p.C1084S 19 42796793 42796793 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP G C uc002otf.1 Hybrid_Cap... view
CLTCL1 p.V1201_splice 22 19189003 19189004 MOLP8_HAEMATOPO... 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
CNTN1 p.M561_splice 12 41337974 41337974 MOLP8_HAEMATOPO... 37 Splice_Site_SNP SNP T C uc001rmm.1 CNTN1_uc009zjy.... Hybrid_Cap... view
CREB3L2 p.T100del 7 137612914 137612916 MOLP8_HAEMATOPO... 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CUBN p.T2741N 10 16942812 16942812 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP G T uc001ioo.2 CUBN_uc009xjq.1... Hybrid_Cap... view
CUBN p.V794F 10 17113892 17113892 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP C A uc001ioo.2 Hybrid_Cap... view
DAB1 p.Q337R 1 57480990 57480990 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP T C uc001cys.1 DAB1_uc001cyt.1... Hybrid_Cap... view
DLC1 p.V1509I 8 12943382 12943382 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP C T uc003wwm.2 DLC1_uc003wwk.1... Hybrid_Cap... view
EIF3A 10 120797628 120797628 MOLP8_HAEMATOPO... 37 Intron SNP T C uc001ldu.2 EIF3A_uc010qsu.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 MOLP8_HAEMATOPO... 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ETV1 7 14028708 14028708 MOLP8_HAEMATOPO... 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
FBN2 5 127664340 127664340 MOLP8_HAEMATOPO... 37 Intron SNP A C uc003kuu.2 FBN2_uc003kuv.2... Hybrid_Cap... view
FBN2 p.P406S 5 127730830 127730830 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP G A uc003kuu.2 FBN2_uc003kuv.2... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 MOLP8_HAEMATOPO... 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FGFR3 4 1809128 1809129 MOLP8_HAEMATOPO... 37 3'UTR Del GT - uc003gdu.2 FGFR3_uc003gdr.... Hybrid_Cap...
FLI1 11 128638217 128638217 MOLP8_HAEMATOPO... 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNA X 153577115 153577116 MOLP8_HAEMATOPO... 37 3'UTR Ins - G uc004fkk.2 FLNA_uc004fki.2... Hybrid_Cap...
FMN2 p.K1625T 1 240555814 240555814 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP A C uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap... view
GNAS 20 57466852 57466852 MOLP8_HAEMATOPO... 37 Intron SNP A C uc002xzw.2 GNAS_uc002xzt.2... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 MOLP8_HAEMATOPO... 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 MOLP8_HAEMATOPO... 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GRIN2B p.K805T 12 13720143 13720143 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP T G uc001rbt.2 Hybrid_Cap... view
GRK4 4 2965725 2965725 MOLP8_HAEMATOPO... 37 5'UTR SNP G A uc003ggn.1 GRK4_uc003ggo.1... Hybrid_Cap... view
GRK4 p.E316G 4 3024155 3024155 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP A G uc003ggn.1 GRK4_uc003ggo.1... Hybrid_Cap... view
GUCY2C 12 14827464 14827466 MOLP8_HAEMATOPO... 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIPK1 p.Q823H 1 114510475 114510475 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP G C uc001eem.2 HIPK1_uc001eel.... Hybrid_Cap... view
HSP90B1 p.E791del 12 104341188 104341190 MOLP8_HAEMATOPO... 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 MOLP8_HAEMATOPO... 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
IRAK2 p.E159* 3 10251323 10251323 MOLP8_HAEMATOPO... 37 Nonsense_Mutation SNP G T uc003bve.1 Hybrid_Cap... view
ITGA10 1 145528457 145528457 MOLP8_HAEMATOPO... 37 Intron SNP A G uc001eoa.2 NBPF10_uc001emp... Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 MOLP8_HAEMATOPO... 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
JAG1 p.T1177M 20 10620273 10620273 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP G A uc002wnw.2 Hybrid_Cap... view
KIAA0802 p.G1467S 18 8825907 8825907 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP G A rs114602899 uc002knr.2 KIAA0802_uc002k... Hybrid_Cap... view
KLK7 19 51480672 51480675 MOLP8_HAEMATOPO... 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
KRAS 12 25362756 25362758 MOLP8_HAEMATOPO... 37 3'UTR Del CTT - uc001rgp.1 KRAS_uc001rgq.1... Hybrid_Cap...
LMNA p.A339A 1 156105772 156105772 MOLP8_HAEMATOPO... 37 Silent SNP G A rs17847242 uc001fni.2 LMNA_uc001fnf.1... Hybrid_Cap... view
MAML2 p.R422Q 11 95825930 95825930 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP C T uc001pfw.1 Hybrid_Cap... view
MAML3 p.Q767_splice 4 140651585 140651587 MOLP8_HAEMATOPO... 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP2K1 15 66679649 66679650 MOLP8_HAEMATOPO... 37 5'UTR Ins - C rs67229745 uc010bhq.2 Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 MOLP8_HAEMATOPO... 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MAP3K14 p.R218_splice 17 43364293 43364294 MOLP8_HAEMATOPO... 37 Splice_Site_Ins Ins - G rs66766023 uc002iiw.1 MAP3K14_uc010da... Hybrid_Cap...
MAP3K6 p.L786P 1 27685976 27685976 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP A G uc001bny.1 MAP3K6_uc009vsw... Hybrid_Cap... view
MLL p.P3178L 11 118376140 118376140 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP C T uc001ptb.2 MLL_uc001pta.2_... Hybrid_Cap... view
MMP9 p.P133R 20 44639148 44639148 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP C G uc002xqz.2 Hybrid_Cap... view
MSH5 p.D516_splice 6 31727290 31727290 MOLP8_HAEMATOPO... 37 Splice_Site_SNP SNP G T uc003nwt.1 MSH5_uc003nwu.1... Hybrid_Cap... view
MSI2 17 55709446 55709446 MOLP8_HAEMATOPO... 37 Intron SNP C T uc002iuz.1 MSI2_uc010wnm.1... Hybrid_Cap... view
MYT1 p.E284E 20 62839401 62839401 MOLP8_HAEMATOPO... 37 Silent SNP A G uc002yii.2 MYT1_uc002yih.2... Hybrid_Cap... view
N4BP2 p.P780Q 4 40122070 40122070 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP C A uc003guy.3 N4BP2_uc010ifq.... Hybrid_Cap... view
NCAM1 11 112832307 112832308 MOLP8_HAEMATOPO... 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 MOLP8_HAEMATOPO... 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.R317C 20 46262365 46262365 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP C T uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap... view
NCOA3 p.Q1276del 20 46279864 46279866 MOLP8_HAEMATOPO... 37 In_Frame_Del Del CAA - rs1132443;rs28529067 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK11 3 130893611 130893611 MOLP8_HAEMATOPO... 37 Intron SNP C T uc003eny.2 NEK11_uc003enx.... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 MOLP8_HAEMATOPO... 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NPR1 1 153665919 153665920 MOLP8_HAEMATOPO... 37 3'UTR Ins - C rs66682713 uc001fcs.3 NPR1_uc010pdz.1... Hybrid_Cap...
NPRL2 p.C96C 3 50387147 50387147 MOLP8_HAEMATOPO... 37 Silent SNP G A uc003daj.1 NPRL2_uc003dai.... Hybrid_Cap... view
NR1H2 p.176_177insQ 19 50881820 50881821 MOLP8_HAEMATOPO... 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NRAS p.Q61L 1 115256529 115256529 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP T A rs11554290 uc009wgu.2 Hybrid_Cap... view
NTRK2 9 87425622 87425622 MOLP8_HAEMATOPO... 37 Intron SNP A G uc004anz.1 NTRK2_uc004anv.... Hybrid_Cap... view
PAX3 2 223066017 223066018 MOLP8_HAEMATOPO... 37 Intron Ins - C rs115619343 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PAX3 2 223158653 223158653 MOLP8_HAEMATOPO... 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PIGU p.V344M 20 33169373 33169373 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP C T uc002xas.2 PIGU_uc010zul.1... Hybrid_Cap... view
PIK3C2A 11 17111198 17111199 MOLP8_HAEMATOPO... 37 3'UTR Del GT - uc001mmq.3 PIK3C2A_uc009yg... Hybrid_Cap...
PIK3C2A p.G1660R 11 17111368 17111368 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP C T uc001mmq.3 PIK3C2A_uc009yg... Hybrid_Cap... view
PIK3C2B p.G1452D 1 204399092 204399092 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP C T uc001haw.2 PIK3C2B_uc010pq... Hybrid_Cap... view
PIK3C2G p.P129del 12 18435399 18435401 MOLP8_HAEMATOPO... 37 In_Frame_Del Del CCC - uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3C2G 12 18800990 18800990 MOLP8_HAEMATOPO... 37 3'UTR Del A - rs16914368 uc010sib.1 PIK3C2G_uc001rd... Hybrid_Cap...
PIK3CG p.I888V 7 106523510 106523510 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP A G uc003vdv.3 PIK3CG_uc003vdu... Hybrid_Cap... view
PLK1 16 23701487 23701487 MOLP8_HAEMATOPO... 37 3'UTR SNP G A uc002dlz.1 Hybrid_Cap... view
PRKCA 17 64298959 64298960 MOLP8_HAEMATOPO... 37 5'UTR Ins - G rs71160558 uc002jfp.1 PRKCA_uc002jfo.... Hybrid_Cap...
PRKCA p.E295K 17 64685130 64685130 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP G A uc002jfp.1 PRKCA_uc002jfo.... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 MOLP8_HAEMATOPO... 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PRKX p.R304L X 3533896 3533896 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP C A uc010nde.2 Hybrid_Cap... view
PTEN p.D115Y 10 89692859 89692859 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP G T uc001kfb.2 Hybrid_Cap... view
RAC1 p.K135T 7 6441557 6441557 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP A C uc003spw.2 RAC1_uc003spx.2... Hybrid_Cap... view
ROR2 p.V136V 9 94519609 94519609 MOLP8_HAEMATOPO... 37 Silent SNP C G uc004arj.1 ROR2_uc004ari.1... Hybrid_Cap... view
RPS6KA5 14 91360733 91360734 MOLP8_HAEMATOPO... 37 Intron Ins - T rs77438853 uc001xys.2 RPS6KA5_uc010tw... Hybrid_Cap...
SNAPC5 15 66782833 66782833 MOLP8_HAEMATOPO... 37 3'UTR SNP C G uc002apu.1 MAP2K1_uc010bhq... Hybrid_Cap... view
SP110 2 231041357 231041357 MOLP8_HAEMATOPO... 37 Intron SNP G A uc002vqg.3 SP110_uc002vqh.... Hybrid_Cap... view
SPEN 1 16266066 16266066 MOLP8_HAEMATOPO... 37 3'UTR SNP G C uc001axk.1 SPEN_uc010obp.1... Hybrid_Cap... view
STK3 p.R489W 8 99468165 99468165 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP G A uc003yio.2 STK3_uc003yip.2... Hybrid_Cap... view
STK31 7 23872024 23872025 MOLP8_HAEMATOPO... 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
STK4 p.R117Q 20 43610574 43610574 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP G A uc002xnb.2 STK4_uc010ggx.2... Hybrid_Cap... view
TNFRSF13B p.G76S 17 16852271 16852271 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP C T uc002gqs.1 TNFRSF13B_uc010... Hybrid_Cap... view
TRIM28 p.P442L 19 59060108 59060108 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP C T uc002qtg.1 TRIM28_uc010eut... Hybrid_Cap... view
TRPS1 8 116635872 116635873 MOLP8_HAEMATOPO... 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TSC1 p.L242P 9 135796762 135796762 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP A G uc004cca.2 TSC1_uc004ccb.3... Hybrid_Cap... view
TTN 2 179391639 179391640 MOLP8_HAEMATOPO... 37 3'UTR Ins - T rs36037175 uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.A10280E 2 179538404 179538404 MOLP8_HAEMATOPO... 37 Missense_Mutation SNP G T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
UBE3B 12 109947357 109947358 MOLP8_HAEMATOPO... 37 Intron Ins - T uc001top.2 UBE3B_uc001toq.... Hybrid_Cap...
VEGFC p.S419_splice 4 177605082 177605084 MOLP8_HAEMATOPO... 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WBP4 13 41657102 41657102 MOLP8_HAEMATOPO... 37 3'UTR SNP A C uc001uxt.2 WBP4_uc010tfd.1... Hybrid_Cap... view