Annotation Summary for Cell Line: NCI-H1092  

Cell line primary name: NCI-H1092
Cell line aliases: H1092
Gender: M
Site Primary: lung
Histology: carcinoma
Hist Subtype1: small_cell_carcinoma
Notes:
Source: ATCC
Expression arrays: CRAZY_p_NCLE_RNA10_HG-U133_Plus_2_D11_569548
SNP arrays: AWASH_p_NCLE_DNAAffy10_GenomeWideSNP_6_G12_542958
Oncomap: yes
Hybrid Capture Sequencing: yes


Mutations in NCI-H1092

GeneProtein
Change
ChrStartEnd SampleNCBI
Build
Variant
Classification
Variant TypeReference
Allele
Tumor
Allele 1
dbSNP IDAnnotation
Transcript
Other
Transcripts
Method View
Reads
Mutation
Assessor
AAK1 p.R843G 2 69708034 69708034 NCIH1092_LUNG 37 Missense_Mutation SNP G C uc002sfp.2 Hybrid_Cap... view
AAK1 p.541_542QQ>Q 2 69741754 69741756 NCIH1092_LUNG 37 In_Frame_Del Del TGT - rs55712143 uc002sfp.2 AAK1_uc010fdk.2... Hybrid_Cap...
ACACA 17 35766564 35766564 NCIH1092_LUNG 37 5'UTR Del A - uc002hno.2 ACACA_uc002hnn.... Hybrid_Cap...
ADAM10 p.N551Y 15 58904051 58904051 NCIH1092_LUNG 37 Missense_Mutation SNP T A uc002afd.1 ADAM10_uc010bgc... Hybrid_Cap... view
ADAM28 8 24211994 24211997 NCIH1092_LUNG 37 3'UTR Del CTAT - rs10610134 uc003xdy.2 ADAM28_uc011laa... Hybrid_Cap...
ADCK4 p.A217T 19 41209688 41209688 NCIH1092_LUNG 37 Missense_Mutation SNP C T rs116013644 uc002oor.2 ADCK4_uc002oop.... Hybrid_Cap... view
ALPK1 4 113347609 113347610 NCIH1092_LUNG 37 Intron Ins - T rs68137453 uc003iap.3 ALPK1_uc003ian.... Hybrid_Cap...
ALPK2 p.EDTST1006del 18 56204388 56204402 NCIH1092_LUNG 37 In_Frame_Del Del CAGTT... - rs60644017;rs117623369 uc002lhj.3 ALPK2_uc002lhk.... Hybrid_Cap...
ASPH p.A264_splice 8 62550924 62550925 NCIH1092_LUNG 37 Splice_Site_Ins Ins - A rs5891816 uc003xuj.2 ASPH_uc011leg.1... Hybrid_Cap...
AURKC 19 57742494 57742507 NCIH1092_LUNG 37 5'UTR Del GGACG... - rs67926438;rs112039303;rs59094959 uc002qoe.2 AURKC_uc002qoc.... Hybrid_Cap...
BRIP1 p.R261* 17 59885965 59885965 NCIH1092_LUNG 37 Nonsense_Mutation SNP T A uc002izk.1 Hybrid_Cap... view
BRSK2 11 1480667 1480667 NCIH1092_LUNG 37 Intron SNP C T uc001ltm.2 BRSK2_uc001lth.... Hybrid_Cap... view
BRSK2 11 1482144 1482144 NCIH1092_LUNG 37 3'UTR SNP C T uc001ltm.2 BRSK2_uc001lti.... Hybrid_Cap... view
BTG1 12 92537706 92537707 NCIH1092_LUNG 37 3'UTR Ins - T rs33983967 uc001tby.3 BTG1_uc001tbv.1... Hybrid_Cap...
C1ORF86 1 2116266 2116266 NCIH1092_LUNG 37 3'UTR SNP C T uc001aix.1 PRKCZ_uc001aiq.... Hybrid_Cap... view
CABC1 1 227171585 227171585 NCIH1092_LUNG 37 Intron Del T - uc001hqm.1 CABC1_uc001hqn.... Hybrid_Cap...
CDH3 p.Q494K 16 68719163 68719163 NCIH1092_LUNG 37 Missense_Mutation SNP C A uc002ewf.2 CDH3_uc010vli.1... Hybrid_Cap... view
CDK11B p.K127_splice 1 1647893 1647894 NCIH1092_LUNG 37 Splice_Site_Ins Ins - TTTCTT rs114930018 uc001agv.1 CDK11B_uc001ags... Hybrid_Cap...
CEP110 p.R1387C 9 123914958 123914958 NCIH1092_LUNG 37 Missense_Mutation SNP C T uc004bkx.1 CEP110_uc004bla... Hybrid_Cap... view
CHD9 p.2164_2165SS>S 16 53338410 53338412 NCIH1092_LUNG 37 In_Frame_Del Del TTC - uc002ehb.2 CHD9_uc002egy.2... Hybrid_Cap...
CLTCL1 p.V1201_splice 22 19189003 19189004 NCIH1092_LUNG 37 Splice_Site_Ins Ins - C rs11386977 uc002zpb.2 CLTCL1_uc011agv... Hybrid_Cap...
COL14A1 p.R1402G 8 121301973 121301973 NCIH1092_LUNG 37 Missense_Mutation SNP C G uc003yox.2 COL14A1_uc003yo... Hybrid_Cap... view
CREB3L2 p.T100del 7 137612914 137612916 NCIH1092_LUNG 37 In_Frame_Del Del TGG - uc003vtw.2 CREB3L2_uc003vt... Hybrid_Cap...
CSMD3 p.T3022A 8 113301678 113301678 NCIH1092_LUNG 37 Missense_Mutation SNP T C uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CSMD3 p.W710* 8 113702123 113702123 NCIH1092_LUNG 37 Nonsense_Mutation SNP C T uc003ynu.2 CSMD3_uc003yns.... Hybrid_Cap... view
CTNNB1 p.D6G 3 41266020 41266020 NCIH1092_LUNG 37 Missense_Mutation SNP A G uc010hia.1 CTNNB1_uc003ckp... Hybrid_Cap... view
CTSS p.A254V 1 150722514 150722514 NCIH1092_LUNG 37 Missense_Mutation SNP G A uc001evn.2 CTSS_uc010pcj.1... Hybrid_Cap... view
CXCL12 10 44873992 44873993 NCIH1092_LUNG 37 Intron Ins - CT rs117617571 uc001jbh.2 CXCL12_uc001jbf... Hybrid_Cap...
DACH1 13 72014625 72014626 NCIH1092_LUNG 37 3'UTR Ins - T rs117109529 uc010thn.1 DACH1_uc010tho.... Hybrid_Cap...
DYRK1A 21 38884966 38884967 NCIH1092_LUNG 37 3'UTR Ins - T rs72430212 uc002ywk.2 DYRK1A_uc002ywi... Hybrid_Cap...
EDNRA 4 148406770 148406770 NCIH1092_LUNG 37 5'UTR SNP A T rs111420520 uc003iky.2 EDNRA_uc011cid.... Hybrid_Cap... view
EPHA6 3 97367230 97367231 NCIH1092_LUNG 37 Intron Ins - A rs115253553 uc010how.1 EPHA6_uc003drs.... Hybrid_Cap...
ERBB4 p.D1257E 2 212248496 212248496 NCIH1092_LUNG 37 Missense_Mutation SNP G T rs79337074 uc002veg.1 ERBB4_uc002veh.... Hybrid_Cap... view
ETV1 7 14028708 14028708 NCIH1092_LUNG 37 5'UTR Del A - rs77190713 uc011jxq.1 ETV1_uc011jxn.1... Hybrid_Cap...
F8 p.R2016L X 154130394 154130394 NCIH1092_LUNG 37 Missense_Mutation SNP C A uc004fmt.2 F8_uc010nvi.1_I... Hybrid_Cap... view
FGFR1OP 6 167453519 167453520 NCIH1092_LUNG 37 3'UTR Ins - T rs115519488 uc003qvj.2 CCR6_uc003qvl.2... Hybrid_Cap...
FLI1 11 128638217 128638217 NCIH1092_LUNG 37 Intron Del G - uc010sbu.1 FLI1_uc010sbt.1... Hybrid_Cap...
FLNA X 153577132 153577133 NCIH1092_LUNG 37 3'UTR Ins - CA rs10692455;rs71733538 uc004fkk.2 FLNA_uc004fki.2... Hybrid_Cap...
FLT4 p.P605Q 5 180048748 180048748 NCIH1092_LUNG 37 Missense_Mutation SNP G T uc003mlz.3 FLT4_uc003mma.3... Hybrid_Cap... view
FMN2 p.PPLPGAGIPPP939del 1 240370914 240370946 NCIH1092_LUNG 37 In_Frame_Del Del GCCCC... - rs4997328;rs4997329 uc010pye.1 FMN2_uc010pyd.1... Hybrid_Cap...
FN1 2 216244182 216244185 NCIH1092_LUNG 37 Intron Del GTAC - uc002vfa.2 FN1_uc002vfb.2_... Hybrid_Cap...
GLI3 p.M111I 7 42187859 42187859 NCIH1092_LUNG 37 Missense_Mutation SNP C T uc011kbh.1 GLI3_uc011kbg.1... Hybrid_Cap... view
GPR112 p.D2657del X 135474445 135474447 NCIH1092_LUNG 37 In_Frame_Del Del GAT - rs3030295 uc004ezu.1 GPR112_uc010nsb... Hybrid_Cap...
GRIA3 X 122318386 122318387 NCIH1092_LUNG 37 Splice_Site_Ins Ins - G rs66632982 uc004etq.3 GRIA3_uc004etr.... Hybrid_Cap...
GUCY2C 12 14827464 14827466 NCIH1092_LUNG 37 Intron Del ATC - rs72525754;rs3083879 uc001rcd.2 GUCY2C_uc009zhz... Hybrid_Cap...
HIF1A p.D662fs 14 62207796 62207796 NCIH1092_LUNG 37 Frame_Shift_Del Del T - uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HIF1A 14 62213929 62213930 NCIH1092_LUNG 37 3'UTR Ins - T rs67890419 uc001xfs.2 HIF1A_uc001xfq.... Hybrid_Cap...
HNF1A 12 121434630 121434631 NCIH1092_LUNG 37 Intron Ins - TCATTCAT rs75100977 uc010szn.1 HNF1A_uc001tze.... Hybrid_Cap...
HSP90B1 p.E791del 12 104341188 104341190 NCIH1092_LUNG 37 In_Frame_Del Del GAA - rs117491163 uc001tkb.1 HSP90B1_uc010sw... Hybrid_Cap...
ILK 11 6630029 6630029 NCIH1092_LUNG 37 Intron Del C - uc001mee.2 ILK_uc001mef.2_... Hybrid_Cap...
IRAK3 12 66641959 66641959 NCIH1092_LUNG 37 3'UTR SNP C T uc001sth.2 IRAK3_uc010ssy.... Hybrid_Cap... view
ITGB1 p.I319M 10 33211649 33211649 NCIH1092_LUNG 37 Missense_Mutation SNP A C uc001iwq.3 ITGB1_uc001iwp.... Hybrid_Cap... view
ITPR2 p.R470_splice 12 26834804 26834805 NCIH1092_LUNG 37 Splice_Site_Ins Ins - ACTC rs66696203;rs59199365 uc001rhg.2 Hybrid_Cap...
KDR p.D392N 4 55976651 55976651 NCIH1092_LUNG 37 Missense_Mutation SNP C T rs2034964 uc003has.2 KDR_uc003hat.1_... Hybrid_Cap... view
KLK7 19 51480672 51480675 NCIH1092_LUNG 37 3'UTR Del GGTT - uc002puo.2 KLK7_uc002pup.2... Hybrid_Cap...
LRP1 p.R2309fs 12 57581135 57581135 NCIH1092_LUNG 37 Frame_Shift_Del Del C - uc001snd.2 Hybrid_Cap...
LRP1B p.L1135F 2 141665561 141665561 NCIH1092_LUNG 37 Missense_Mutation SNP C A uc002tvj.1 LRP1B_uc010fnl.... Hybrid_Cap... view
LRP2 2 169985141 169985141 NCIH1092_LUNG 37 3'UTR SNP G T uc002ues.2 Hybrid_Cap... view
LRRK2 p.S473_splice 12 40651180 40651180 NCIH1092_LUNG 37 Splice_Site_SNP SNP G T uc001rmg.3 LRRK2_uc001rmh.... Hybrid_Cap... view
MAF 16 79628537 79628537 NCIH1092_LUNG 37 Intron Del T - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAF 16 79628325 79628325 NCIH1092_LUNG 37 3'UTR Del A - uc002ffm.2 MAF_uc002ffn.2_... Hybrid_Cap...
MAML3 p.Q767_splice 4 140651585 140651587 NCIH1092_LUNG 37 Splice_Site_Del Del CTG - uc003ihz.1 MGST2_uc010ioi.... Hybrid_Cap...
MAP3K1 p.T949del 5 56177849 56177851 NCIH1092_LUNG 37 In_Frame_Del Del CAA - uc003jqw.3 Hybrid_Cap...
MKL1 p.I88V 22 40825649 40825649 NCIH1092_LUNG 37 Missense_Mutation SNP T C uc003ayv.1 MKL1_uc003ayw.1... Hybrid_Cap... view
MMP20 p.G217_splice 11 102479830 102479830 NCIH1092_LUNG 37 Splice_Site_SNP SNP C A uc001phc.2 Hybrid_Cap... view
MSH3 p.PPA66del 5 79950742 79950750 NCIH1092_LUNG 37 In_Frame_Del Del CCCCC... - rs60484572;rs1047489 uc003kgz.2 DHFR_uc011ctl.1... Hybrid_Cap...
MYLK p.E1066del 3 123419117 123419119 NCIH1092_LUNG 37 In_Frame_Del Del TTC - rs72491150 uc003ego.2 MYLK_uc011bjw.1... Hybrid_Cap...
MYLK p.E921K 3 123419554 123419554 NCIH1092_LUNG 37 Missense_Mutation SNP C T uc003ego.2 MYLK_uc011bjw.1... Hybrid_Cap... view
NAV3 p.E1999V 12 78582498 78582498 NCIH1092_LUNG 37 Missense_Mutation SNP A T uc001syp.2 NAV3_uc001syo.2... Hybrid_Cap... view
NCAM1 11 112832276 112832277 NCIH1092_LUNG 37 5'UTR Ins - G uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832307 112832308 NCIH1092_LUNG 37 5'UTR Ins - A rs117108942 uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCAM1 11 112832340 112832340 NCIH1092_LUNG 37 5'UTR Del C - uc009yyq.1 NCAM1_uc001pno.... Hybrid_Cap...
NCOA3 p.QQ1275del 20 46279861 46279866 NCIH1092_LUNG 37 In_Frame_Del Del CAGCA... - rs11472494;rs67218125;rs1132443;rs28529067 uc002xtk.2 NCOA3_uc010ght.... Hybrid_Cap...
NEK11 3 130893765 130893765 NCIH1092_LUNG 37 Intron SNP A T uc003eny.2 NEK11_uc003enx.... Hybrid_Cap... view
NEK2 p.R361W 1 211840478 211840478 NCIH1092_LUNG 37 Missense_Mutation SNP G A uc001hir.1 NEK2_uc001hiq.1... Hybrid_Cap... view
NEK3 p.K313_splice 13 52718050 52718051 NCIH1092_LUNG 37 Splice_Site_Ins Ins - T rs72514762 uc001vgh.2 NEK3_uc001vgg.2... Hybrid_Cap...
NFATC1 18 77287653 77287654 NCIH1092_LUNG 37 3'UTR Del AA - uc010xfg.1 NFATC1_uc002lnd... Hybrid_Cap...
NFIA 1 61921185 61921186 NCIH1092_LUNG 37 3'UTR Ins - T rs57270124;rs76131997 uc010oos.1 NFIA_uc001czy.2... Hybrid_Cap...
NR1H2 p.176_177insQ 19 50881820 50881821 NCIH1092_LUNG 37 In_Frame_Ins Ins - AAC rs66783852;rs112359270 uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap...
NR1H2 p.V186L 19 50881859 50881859 NCIH1092_LUNG 37 Missense_Mutation SNP G T uc010enw.2 NR1H2_uc002prv.... Hybrid_Cap... view
NTRK3 p.D411N 15 88670455 88670455 NCIH1092_LUNG 37 Missense_Mutation SNP C T uc002bme.1 NTRK3_uc002bmh.... Hybrid_Cap... view
PAX3 2 223158653 223158653 NCIH1092_LUNG 37 Intron Del T - rs112753212 uc002vmt.1 PAX3_uc002vmy.1... Hybrid_Cap...
PDK4 7 95221928 95221928 NCIH1092_LUNG 37 Intron Del A - uc003uoa.2 PDK4_uc003unz.2... Hybrid_Cap...
PGGT1B 5 114548071 114548072 NCIH1092_LUNG 37 3'UTR Ins - C uc003kqw.3 PGGT1B_uc003kqx... Hybrid_Cap...
PGR 11 100933598 100933599 NCIH1092_LUNG 37 Intron Ins - AATGA rs35148438 uc001pgh.2 PGR_uc001pgg.2_... Hybrid_Cap...
PIP4K2A p.A120S 10 22880692 22880692 NCIH1092_LUNG 37 Missense_Mutation SNP C A uc001irl.3 PIP4K2A_uc010qc... Hybrid_Cap... view
PKN3 p.D880D 9 131482855 131482855 NCIH1092_LUNG 37 Silent SNP C T uc004bvw.2 PKN3_uc010myh.2... Hybrid_Cap... view
PRKDC p.L1244fs 8 48805816 48805817 NCIH1092_LUNG 37 Frame_Shift_Ins Ins - G rs67588121 uc003xqi.2 PRKDC_uc003xqj.... Hybrid_Cap...
PTPRD 9 8454584 8454584 NCIH1092_LUNG 37 Intron SNP C A uc003zkk.2 PTPRD_uc003zkp.... Hybrid_Cap... view
RECQL4 p.R766fs 8 145738768 145738768 NCIH1092_LUNG 37 Frame_Shift_Del Del G - uc003zdj.2 Hybrid_Cap...
RET p.Y791N 10 43613907 43613907 NCIH1092_LUNG 37 Missense_Mutation SNP T A uc001jal.2 RET_uc001jak.1_... Hybrid_Cap... view
RET p.A1105V 10 43623686 43623686 NCIH1092_LUNG 37 Missense_Mutation SNP C T uc001jal.2 Hybrid_Cap... view
RPN1 p.T144A 3 128356845 128356845 NCIH1092_LUNG 37 Missense_Mutation SNP T C uc003ekr.1 RPN1_uc011bkq.1... Hybrid_Cap... view
SEPT5 22 19709595 19709595 NCIH1092_LUNG 37 Intron Del C - uc002zpv.1 SEPT5_uc002zpw.... Hybrid_Cap...
SETDB1 p.A1090D 1 150935173 150935173 NCIH1092_LUNG 37 Missense_Mutation SNP C A rs75743857 uc001evu.2 SETDB1_uc001evv... Hybrid_Cap... view
SMARCA4 p.G784E 19 11123701 11123701 NCIH1092_LUNG 37 Missense_Mutation SNP G A uc010dxo.2 SMARCA4_uc002mq... Hybrid_Cap... view
STK10 5 171615068 171615073 NCIH1092_LUNG 37 5'UTR Del GGCTC... - uc003mbo.1 Hybrid_Cap...
STK31 7 23872024 23872025 NCIH1092_LUNG 37 3'UTR Ins - TTTG rs66787534 uc003sws.3 STK31_uc003swt.... Hybrid_Cap...
TCF21 6 134210497 134210498 NCIH1092_LUNG 37 5'UTR Ins - TCTC rs35199378 uc003qei.3 TCF21_uc003qej.... Hybrid_Cap...
TEK p.S164S 9 27169491 27169491 NCIH1092_LUNG 37 Silent SNP A G uc003zqi.3 TEK_uc010mjc.1_... Hybrid_Cap... view
TLE1 p.G559A 9 84205903 84205903 NCIH1092_LUNG 37 Missense_Mutation SNP C G uc004alz.2 TLE1_uc004aly.2... Hybrid_Cap... view
TLN1 p.N251K 9 35723978 35723978 NCIH1092_LUNG 37 Missense_Mutation SNP A T uc003zxt.2 TLN1_uc003zxu.3... Hybrid_Cap... view
TMEM123 11 102269398 102269398 NCIH1092_LUNG 37 3'UTR Del G - uc001pha.2 TMEM123_uc009yx... Hybrid_Cap...
TNFRSF10B p.T393S 8 22880329 22880329 NCIH1092_LUNG 37 Missense_Mutation SNP G C uc003xcu.2 TNFRSF10B_uc003... Hybrid_Cap... view
TNRC6B p.Q1328del 22 40697177 40697179 NCIH1092_LUNG 37 In_Frame_Del Del GCA - rs114291931 uc011aor.1 TNRC6B_uc003aym... Hybrid_Cap...
TP53 p.V225_splice 17 7577610 7577610 NCIH1092_LUNG 37 Splice_Site_SNP SNP T G uc002gim.2 TP53_uc002gig.1... Hybrid_Cap... view
TRIM33 1 114940215 114940216 NCIH1092_LUNG 37 3'UTR Ins - G rs68133208 uc001eew.2 TRIM33_uc010owr... Hybrid_Cap...
TRPS1 8 116635872 116635873 NCIH1092_LUNG 37 5'UTR Ins - A rs76893349 uc003yny.2 TRPS1_uc011lhy.... Hybrid_Cap...
TRRAP p.S1987N 7 98553812 98553812 NCIH1092_LUNG 37 Missense_Mutation SNP G A uc003upp.2 TRRAP_uc011kis.... Hybrid_Cap... view
TTN p.T22746E 2 179434918 179434919 NCIH1092_LUNG 37 Missense_Mutation DNP GT TC uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap...
TTN p.P18402L 2 179453543 179453543 NCIH1092_LUNG 37 Missense_Mutation SNP G A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.E10026* 2 179543492 179543492 NCIH1092_LUNG 37 Nonsense_Mutation SNP C A uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.A2606T 2 179637875 179637875 NCIH1092_LUNG 37 Missense_Mutation SNP C T uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
TTN p.K223_splice 2 179664550 179664550 NCIH1092_LUNG 37 Splice_Site_SNP SNP A G uc010zfg.1 TTN_uc010zfh.1_... Hybrid_Cap... view
VEGFC p.S419_splice 4 177605082 177605084 NCIH1092_LUNG 37 Splice_Site_Del Del TCA - uc003ius.1 Hybrid_Cap...
WHSC1 p.E683D 4 1953870 1953870 NCIH1092_LUNG 37 Missense_Mutation SNP A T uc003gdz.3 WHSC1_uc003geb.... Hybrid_Cap... view